GO:0001660

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Name fever generation
Categary Process
Go Slim No
Go Link GO:0001660
Unique Molecular Interactions 868
Total Molecular Interactions 1288
Total Single Events 13571
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fever generation. They are ordered first by their pain relevance and then by number of times they were reported for fever generation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
5 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
6 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
7 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
8 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
9 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
10 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
11 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
12 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
13 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
14 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
15 INT158752 Binding of TRPV1 and Rvm 1 0.05 1.6 3.1
16 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08
17 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
18 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
19 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
20 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
21 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
22 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
23 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
24 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
25 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
26 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
27 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
28 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
29 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
30 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
31 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
32 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
33 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28
34 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
35 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
36 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
37 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
38 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
39 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
40 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
41 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
42 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
43 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
44 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
45 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
46 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
47 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
48 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
49 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
50 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
51 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
52 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
53 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
54 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
55 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
56 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
57 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
58 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
59 INT147654 DYT10 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.93 1.62
60 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
61 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
62 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
63 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
64 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
65 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
66 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
67 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
68 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
69 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
70 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
71 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
72 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
73 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
74 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
75 INT139768 Binding of TRPV1 and ICK 1 0.41 1.59 1.42
76 INT139767 ICK Regulation of TRPV1 1 0.30 1.59 1.42
77 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
78 INT116827 Binding of UCHL1 and TRPV1 1 0.41 0.88 1.39
79 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
80 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
81 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
82 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
83 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
84 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
85 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35
86 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
87 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
88 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
89 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
90 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
91 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29
92 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
93 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
94 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
95 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
96 INT342990 TRPV1 Positive_regulation of Gene_expression of SFTPA1 1 0.06 1.44 1.26
97 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
98 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24
99 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
100 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
101 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
102 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23
103 INT342988 HCL1 Positive_regulation of TRPV1 1 0.04 1.15 1.21
104 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
105 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
106 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
107 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
108 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
109 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
110 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
111 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
112 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
113 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
114 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
115 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
116 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
117 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
118 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12
119 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
120 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
121 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
122 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
123 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
124 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
125 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
126 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
127 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
128 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
129 INT105690 Ngf Positive_regulation of TRPV1 1 0.05 1.43 1.08
130 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
131 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
132 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
133 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
134 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
135 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
136 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
137 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
138 INT162250 Binding of TRPV1 and Grm5 1 0.01 0.8 1.03
139 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
140 INT114553 Binding of Trpv1 and Col4a4 1 0.01 0.44 1.03
141 INT114554 Binding of St3gal3 and Trpv1 1 0.01 0.44 1.03
142 INT182561 Ptger3 Positive_regulation of Ptger1 1 0.15 1.31 1.02
143 INT182566 Ptger3 Positive_regulation of Ptgir 1 0.08 1.31 1.02
144 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
145 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
146 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97
147 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
148 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
149 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
150 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
151 INT93307 CAP1 Positive_regulation of TRPV1 1 0.15 0.07 0.96
152 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
153 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
154 INT156608 Trpv1 Regulation of Nav1 1 0.51 0.52 0.95
155 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
156 INT144902 Binding of Trpv1 and Pars2 1 0.17 0 0.95
157 INT199396 Prok2 Regulation of Trpv1 1 0.43 1.23 0.94
158 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94
159 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94
160 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
161 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
162 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
163 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
164 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
165 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9
166 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
167 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
168 INT21944 Il1a Negative_regulation of Gnrh1 1 0.34 0 0.89
169 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
170 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
171 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
172 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
173 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
174 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
175 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
176 INT138073 Binding of TRPV1 and TUFMP1 1 0.03 0.46 0.86
177 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
178 INT193278 Brs3 Positive_regulation of Gene_expression of Trpv1 1 0.04 0.09 0.86
179 INT114546 Ins1 Positive_regulation of Positive_regulation of Trpv1 1 0.39 0.19 0.86
180 INT182555 Ptgir Regulation of Trpv1 1 0.12 0.61 0.85
181 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
182 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84
183 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84
184 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
185 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
186 INT10275 Il1b Positive_regulation of Gene_expression of Penk 1 0.49 0.75 0.83
187 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
188 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
189 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
190 INT84717 Il1b Regulation of Cpox 1 0.00 0.37 0.83
191 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
192 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
193 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
194 INT299987 SPANXB1 Positive_regulation of TRPV1 1 0.20 0.71 0.82
195 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
196 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
197 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
198 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
199 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
200 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8

Single Events

The table below shows the top 100 pain related interactions that have been reported for fever generation. They are ordered first by their pain relevance and then by number of times they were reported in fever generation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
2 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
3 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
4 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81
5 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05
6 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
7 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
8 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
9 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
10 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
11 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
12 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
13 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98
14 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46
15 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
16 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
17 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
18 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
19 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
20 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
21 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
22 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35
23 INT49436 Binding of TRPV1 145 0.48 38.35 55.08
24 INT9383 Localization of TRPV1 98 0.81 33.23 46.24
25 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
26 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
27 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
28 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
29 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
30 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
31 INT9347 Localization of Il1b 58 0.81 26.13 31.53
32 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
33 INT5966 Localization of Il1a 50 0.78 22.91 26.54
34 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28
35 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
36 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
37 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
38 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
39 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
40 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47
41 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
42 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
43 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
44 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
45 INT48081 Localization of Il1b 46 0.80 21.59 22.4
46 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
47 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
48 INT77902 Negative_regulation of Positive_regulation of TRPV1 30 0.59 9.36 19.2
49 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
50 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
51 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
52 INT101501 Phosphorylation of TRPV1 31 0.82 9.26 17.27
53 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82
54 INT103828 Negative_regulation of Gene_expression of TRPV1 23 0.59 13.63 13.81
55 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
56 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36
57 INT101494 Regulation of Positive_regulation of Trpv1 18 0.62 6.57 12.9
58 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
59 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
60 INT97237 Transcription of TRPV1 33 0.72 10.56 12.4
61 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
62 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08
63 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
64 INT23122 Gene_expression of Ptger3 31 0.72 11.94 11.37
65 INT112037 Negative_regulation of Positive_regulation of Trpv1 19 0.59 8.9 10.55
66 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
67 INT2828 Positive_regulation of Ptger3 26 0.68 8.01 9.63
68 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
69 INT89053 Positive_regulation of Phosphorylation of Trpv1 16 0.70 8.89 9.39
70 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78
71 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
72 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
73 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
74 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
75 INT49932 Gene_expression of Ptger3 33 0.71 8.77 7.39
76 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
77 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71
78 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7
79 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
80 INT50130 Positive_regulation of Ptger3 13 0.67 5.23 6.47
81 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
82 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
83 INT23034 Positive_regulation of Il1a 15 0.70 8.75 6.29
84 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
85 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
86 INT262 Localization of Ptger3 17 0.61 3.03 6.1
87 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99
88 INT80750 Binding of Il1b 11 0.47 7.97 5.95
89 INT107441 Positive_regulation of Gene_expression of Il1rn 7 0.46 3.24 5.95
90 INT125187 Positive_regulation of Transcription of Trpv1 9 0.69 8.98 5.77
91 INT116490 Positive_regulation of Localization of TRPV1 9 0.68 3.86 5.67
92 INT58468 Negative_regulation of Gene_expression of IL1A 10 0.58 9.39 5.57
93 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
94 INT10705 Binding of Il1b 9 0.36 2.8 5.53
95 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
96 INT58338 Negative_regulation of Localization of Il1a 8 0.25 3.13 5.18
97 INT94357 Positive_regulation of Transcription of Trpv1 11 0.50 3.63 5.05
98 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05
99 INT101502 Positive_regulation of Phosphorylation of TRPV1 5 0.70 2.38 4.83
100 INT134610 Positive_regulation of Phosphorylation of Trpv1 9 0.69 4.51 4.74
101 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
102 INT50309 Binding of Il1a 22 0.40 5.4 4.49
103 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48
104 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41
105 INT9378 Regulation of Positive_regulation of TRPV1 9 0.45 2.36 4.26
106 INT23035 Regulation of Il1a 6 0.60 5.69 4.25
107 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
108 INT15462 Negative_regulation of Il1a 4 0.59 4.68 4.17
109 INT19189 Localization of IL1A 14 0.78 9.02 3.78
110 INT76707 Negative_regulation of Gene_expression of Ptger3 6 0.20 2.56 3.73
111 INT64203 Positive_regulation of Negative_regulation of Trpv1 5 0.47 3.39 3.67
112 INT99186 Negative_regulation of Negative_regulation of TRPV1 4 0.41 2.49 3.65
113 INT141253 Regulation of Transcription of Trpv1 7 0.62 3.54 3.62
114 INT111362 Regulation of Localization of TRPV1 5 0.44 1.76 3.54
115 INT83646 Binding of Il1rn 12 0.37 4.41 3.51
116 INT40232 Transcription of Il1rn 8 0.53 9.6 3.37
117 INT114733 Regulation of Binding of TRPV1 3 0.48 0.3 3.22
118 INT58063 Negative_regulation of Binding of Trpv1 6 0.59 1.54 3.21
119 INT138350 Regulation of Phosphorylation of Trpv1 6 0.58 1.87 3.16
120 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14
121 INT54619 Negative_regulation of Positive_regulation of Il1a 6 0.42 5.68 3.12
122 INT120490 Regulation of Regulation of TRPV1 4 0.45 2.36 3.02
123 INT196872 Negative_regulation of Localization of Trpv1 4 0.42 1.47 2.98
124 INT69822 Binding of Ptger3 9 0.39 2.98 2.97
125 INT114263 Negative_regulation of Negative_regulation of Trpv1 6 0.43 2.71 2.92
126 INT16447 Binding of IL1A 10 0.45 4.01 2.78
127 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
128 INT66630 Transcription of Ptger3 4 0.67 1.74 2.74
129 INT116819 Negative_regulation of Localization of TRPV1 3 0.43 1.75 2.71
130 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
131 INT118888 Regulation of Localization of Trpv1 5 0.44 1.43 2.64
132 INT125191 Regulation of Transcription of Trpv1 6 0.45 4.54 2.62
133 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
134 INT76679 Positive_regulation of Transcription of Il1rn 1 0.37 9.13 2.55
135 INT62064 Negative_regulation of Gene_expression of Il1rn 6 0.32 4.81 2.53
136 INT108691 Regulation of Binding of Trpv1 3 0.58 1.91 2.51
137 INT169785 Localization of Ptger3 9 0.57 1.35 2.5
138 INT69981 Positive_regulation of Negative_regulation of Il1rn 2 0.09 3.28 2.48
139 INT49984 Localization of Il1a 5 0.77 3.61 2.42
140 INT5968 Positive_regulation of Localization of Il1a 4 0.65 1.36 2.42
141 INT108395 Positive_regulation of Binding of Trpv1 5 0.50 1.26 2.39
142 INT195917 Regulation of Phosphorylation of Trpv1 2 0.52 1.86 2.29
143 INT262548 Regulation of Localization of Trpv1 2 0.45 0.73 2.25
144 INT131928 Localization of Il1rn 3 0.74 2.22 2.24
145 INT76706 Positive_regulation of Gene_expression of Ptger3 5 0.22 0.49 2.23
146 INT150884 Transcription of Il1a 6 0.47 3.12 2.19
147 INT116784 Regulation of Regulation of Trpv1 5 0.60 1.76 2.18
148 INT261812 Positive_regulation of Negative_regulation of Trpv1 3 0.46 1.26 2.11
149 INT49988 Positive_regulation of Gene_expression of Il1a 2 0.47 1.49 2.11
150 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02
151 INT168275 Phosphorylation of Il1b 1 0.79 2.39 2.01
152 INT116033 Negative_regulation of Transcription of Il1b 4 0.42 2.05 1.94
153 INT144944 Positive_regulation of Negative_regulation of TRPV1 3 0.46 0.84 1.89
154 INT126539 Negative_regulation of Transcription of Trpv1 9 0.59 1.52 1.8
155 INT124014 Negative_regulation of Positive_regulation of Ptger3 1 0.05 0 1.78
156 INT89926 Regulation of IL1A 10 0.60 7.12 1.72
157 INT2826 Negative_regulation of Localization of Ptger3 6 0.37 0.9 1.64
158 INT149510 Negative_regulation of Transcription of Trpv1 5 0.56 3.74 1.5
159 INT172870 Negative_regulation of Ptger3 6 0.23 2.96 1.48
160 INT49987 Transcription of Il1a 1 0.68 0.66 1.4
161 INT330442 Negative_regulation of Regulation of Trpv1 1 0.37 1.69 1.38
162 INT29997 Binding of Ptger3 5 0.17 3.32 1.34
163 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32
164 INT129253 Positive_regulation of Positive_regulation of Il1a 5 0.49 2.97 1.31
165 INT162037 Negative_regulation of Regulation of TRPV1 2 0.43 2.47 1.31
166 INT2829 Negative_regulation of Ptger3 5 0.43 1.63 1.29
167 INT2825 Regulation of Localization of Ptger3 3 0.23 0.3 1.29
168 INT182548 Regulation of Regulation of Trpv1 1 0.26 1.52 1.27
169 INT94744 Regulation of Transcription of Il1b 3 0.44 2.83 1.26
170 INT9376 Positive_regulation of Regulation of TRPV1 3 0.47 1.42 1.26
171 INT162757 Regulation of Localization of Il1a 3 0.37 1.22 1.25
172 INT122662 Negative_regulation of Negative_regulation of Trpv1 1 0.59 1.74 1.22
173 INT101022 Regulation of Il1rn 5 0.44 2.15 1.21
174 INT59082 Regulation of Gene_expression of IL1A 3 0.45 2.07 1.2
175 INT155676 Positive_regulation of Regulation of Trpv1 2 0.47 0.97 1.17
176 INT54830 Regulation of Ptger3 4 0.39 1.31 1.16
177 INT9348 Regulation of Localization of Il1b 2 0.27 0.14 1.04
178 INT50989 Regulation of Positive_regulation of Il1b 2 0.42 0.86 1.02
179 INT332476 Protein_catabolism of Trpv1 1 0.65 0.1 1.02
180 INT161368 Protein_catabolism of TRPV1 2 0.68 1.32 1.01
181 INT53571 Negative_regulation of Localization of Il1a 2 0.50 1.59 0.99
182 INT190077 Regulation of Transcription of Il1a 2 0.02 0.87 0.99
183 INT292529 Phosphorylation of Il1rn 1 0.09 1 0.97
184 INT16446 Transcription of IL1A 4 0.69 1.76 0.96
185 INT152082 Negative_regulation of Phosphorylation of Trpv1 2 0.43 0.28 0.95
186 INT145851 Negative_regulation of Positive_regulation of Il1rn 1 0.08 0.7 0.95
187 INT140787 Regulation of Ptger3 3 0.43 0.32 0.93
188 INT145852 Negative_regulation of Negative_regulation of Il1rn 1 0.08 0.69 0.93
189 INT168280 Positive_regulation of Phosphorylation of Il1b 1 0.49 1.1 0.93
190 INT344365 Phosphorylation of Il1a 1 0.61 1.01 0.92
191 INT103183 Regulation of Phosphorylation of TRPV1 2 0.41 0.44 0.84
192 INT83454 Positive_regulation of Negative_regulation of IL1A 1 0.50 0.62 0.81
193 INT269642 Binding of EPHA3 4 0.10 0.22 0.8
194 INT23033 Negative_regulation of Positive_regulation of Il1a 2 0.42 0.76 0.78
195 INT118441 Positive_regulation of Transcription of TRPV1 3 0.70 0.57 0.73
196 INT160378 Protein_catabolism of Trpv1 2 0.89 0.61 0.73
197 INT53576 Regulation of Gene_expression of Il1a 2 0.41 0.6 0.73
198 INT127822 Negative_regulation of Transcription of Il1b 2 0.42 1.2 0.72
199 INT169791 Negative_regulation of Localization of Ptger3 1 0.30 0.77 0.72
200 INT169787 Regulation of Localization of Ptger3 1 0.32 0.77 0.72
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