GO:0001666

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Name response to hypoxia
Categary Process
Go Slim No
Go Link GO:0001666
Unique Molecular Interactions 7302
Total Molecular Interactions 10389
Total Single Events 104749
Pain Genes Associated 325

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to hypoxia. They are ordered first by their pain relevance and then by number of times they were reported for response to hypoxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
5 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
6 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
7 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
8 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
9 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
10 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
11 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
12 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
13 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
14 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
15 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
16 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
17 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
18 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
19 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
20 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
21 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
22 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
23 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
24 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
25 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
26 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05
27 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
28 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
29 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
30 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
31 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
32 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
33 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
34 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
35 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
36 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
37 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
38 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
39 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
40 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
41 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
42 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
43 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
44 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
45 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
46 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
47 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
48 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
49 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
50 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
51 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
52 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
53 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27
54 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26
55 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
56 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
57 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
58 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
59 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
60 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
61 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
62 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
63 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
64 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
65 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
66 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
67 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
68 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
69 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
70 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
71 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
72 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
73 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
74 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
75 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01
76 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
77 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
78 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
79 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97
80 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
81 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
82 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
83 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
84 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
85 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
86 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
87 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
88 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
89 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
90 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
91 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
92 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
93 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
94 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
95 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
96 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
97 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
98 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
99 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
100 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
101 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
102 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
103 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
104 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
105 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
106 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
107 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
108 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
109 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
110 INT14910 Binding of GPR182 and SIT1 1 0.02 1.87 1.73
111 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
112 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
113 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
114 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
115 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
116 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
117 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
118 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
119 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
120 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
121 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
122 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
123 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
124 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
125 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
126 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
127 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
128 INT32839 Binding of Trh and Penk 2 0.42 0 1.63
129 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
130 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
131 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
132 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
133 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
134 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
135 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
136 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
137 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
138 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
139 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
140 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
141 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
142 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
143 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
144 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
145 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
146 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
147 INT40887 Penk Regulation of Th 1 0.04 0 1.53
148 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
149 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
150 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
151 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
152 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
153 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
154 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
155 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
156 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
157 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
158 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
159 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
160 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
161 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
162 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
163 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
164 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
165 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
166 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
167 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
168 INT30872 Abat Positive_regulation of Localization of Gast 1 0.26 0 1.43
169 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
170 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
171 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42
172 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
173 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
174 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
175 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
176 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
177 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
178 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
179 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
180 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
181 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
182 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
183 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
184 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
185 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
186 INT33988 TRH Regulation of Localization of IGKV1D-39 1 0.12 0.47 1.35
187 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
188 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
189 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
190 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
191 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
192 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
193 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
194 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
195 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
196 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
197 INT2641 Binding of Pomc and Lct 2 0.31 0.57 1.32
198 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
199 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
200 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to hypoxia. They are ordered first by their pain relevance and then by number of times they were reported in response to hypoxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT3439 Localization of Abat 1017 0.78 112.39 727.06
3 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
4 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
5 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
6 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
7 INT6852 Localization of TNF 883 0.81 705.95 270.84
8 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
9 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
10 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43
11 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34
12 INT6481 Binding of TNF 624 0.48 510.2 214.82
13 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
14 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
15 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
16 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
17 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98
18 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36
19 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
20 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
21 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
22 INT2910 Regulation of Abat 169 0.62 36.95 153.53
23 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48
24 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
25 INT9660 Regulation of TNF 363 0.62 312.94 139.99
26 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
27 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
28 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
29 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
30 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
31 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
32 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
33 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
34 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
35 INT7327 Regulation of Th 164 0.62 29.67 110.14
36 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
37 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
38 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
39 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
40 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
41 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
42 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
43 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
44 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
45 INT10166 Localization of Tnf 237 0.81 153.95 88.64
46 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59
47 INT339 Regulation of Trh 156 0.62 39.27 83.55
48 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
49 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
50 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
51 INT403 Localization of Trh 241 0.81 28.55 81.45
52 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
53 INT920 Localization of PLOD1 223 0.81 42.25 78.7
54 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
55 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
56 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
57 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
58 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
59 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
60 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
61 INT1376 Binding of Trh 121 0.48 20 69.86
62 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
63 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
64 INT6849 Localization of IL1B 229 0.81 112.56 69.63
65 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
66 INT2212 Binding of Abat 89 0.48 18.36 63.99
67 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
68 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
69 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
70 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36
71 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
72 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
73 INT3920 Localization of Ldha 241 0.81 83.08 58.72
74 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
75 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35
76 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
77 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
78 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
79 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
80 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
81 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
82 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
83 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
84 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
85 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
86 INT122041 Binding of Ppara 308 0.48 189.17 51.48
87 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
88 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
89 INT19488 Localization of ABAT 56 0.69 21.51 50.56
90 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5
91 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
92 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
93 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43
94 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
95 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
96 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
97 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
98 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
99 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
100 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63
101 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
102 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
103 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
104 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
105 INT13354 Transcription of TNF 108 0.72 85.81 42.32
106 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
107 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03
108 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
109 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
110 INT350 Localization of Th 79 0.80 10.26 41.17
111 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
112 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55
113 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33
114 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
115 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
116 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
117 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
118 INT30817 Gene_expression of Th 142 0.76 33.56 38.12
119 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
120 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81
121 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
122 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
123 INT13501 Binding of Drd2 65 0.48 23.76 35.6
124 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
125 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
126 INT7326 Transcription of Th 83 0.72 13.5 35.33
127 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
128 INT6484 Binding of IL1B 122 0.47 75.84 35.07
129 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
130 INT103094 Binding of PPARA 308 0.47 177.26 34.75
131 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
132 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
133 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
134 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07
135 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
136 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4
137 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
138 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72
139 INT65698 Localization of CCL2 118 0.81 77.54 32.69
140 INT99610 Localization of MMP9 126 0.79 48.46 32.67
141 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
142 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
143 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
144 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
145 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72
146 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
147 INT9347 Localization of Il1b 58 0.81 26.13 31.53
148 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
149 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
150 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
151 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
152 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
153 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
154 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51
155 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
156 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
157 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
158 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
159 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
160 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
161 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
162 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
163 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
164 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
165 INT82882 Localization of Ccl2 61 0.80 41.96 28
166 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
167 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
168 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54
169 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
170 INT10799 Localization of ENG 63 0.78 18.67 27.28
171 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
172 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
173 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79
174 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
175 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61
176 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
177 INT5966 Localization of Il1a 50 0.78 22.91 26.54
178 INT100861 Binding of CRP 179 0.48 175.2 26.45
179 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
180 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29
181 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
182 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
183 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9
184 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74
185 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
186 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
187 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
188 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
189 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
190 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
191 INT12484 Binding of Drd2 45 0.48 15.17 24.72
192 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
193 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
194 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
195 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
196 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
197 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
198 INT89854 Regulation of Nos2 49 0.61 42.58 24.1
199 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
200 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
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