GO:0001678

From wiki-pain
Jump to: navigation, search
Name cellular glucose homeostasis
Categary Process
Go Slim No
Go Link GO:0001678
Unique Molecular Interactions 116
Total Molecular Interactions 136
Total Single Events 1185
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular glucose homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for cellular glucose homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
2 INT144153 Socs6 Positive_regulation of Gene_expression of Gabrg1 1 0.07 0 1.16
3 INT253827 Cck Regulation of Cartpt 1 0.41 0 1.16
4 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
5 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
6 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
7 INT253829 Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72
8 INT253833 Positive_regulation of Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72
9 INT253831 Cck Positive_regulation of Gene_expression of Cartpt 1 0.48 0.23 0.69
10 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67
11 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
12 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
13 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
14 INT110300 Cartpt Regulation of Adarb1 1 0.14 0 0.49
15 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
16 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29
17 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18
18 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18
19 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
20 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17
21 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17
22 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17
23 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
24 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
25 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
26 INT338449 Nps Regulation of Alms1 1 0.04 0.13 0.14
27 INT308534 Binding of HIVEP1 and Alms1 1 0.00 0.96 0.13
28 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13
29 INT100478 Binding of Camk1d and Alms1 1 0.17 0 0.12
30 INT187468 Alms1 Positive_regulation of H2-D1 1 0.02 0.32 0.11
31 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
32 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11
33 INT222501 Cartpt Negative_regulation of Localization of Prl 1 0.08 0 0.1
34 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
35 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
36 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
37 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
38 INT348971 Binding of MOG and CARTPT 1 0.06 0.73 0.08
39 INT243213 Myst2 Negative_regulation of Alms1 1 0.01 0.91 0.08
40 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
41 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
42 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
43 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
44 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
45 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
46 INT256570 Bglap Positive_regulation of Gene_expression of Gck 1 0.48 0.43 0.04
47 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
48 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
49 INT251067 Plvap Regulation of Protein_catabolism of Alms1 1 0.03 0 0.03
50 INT251074 Cldn3 Regulation of Protein_catabolism of Alms1 1 0.09 0 0.03
51 INT184131 Binding of Socs6 and Irs2 1 0.11 0.2 0.03
52 INT214171 Binding of DST and Cartpt 1 0.01 0.21 0.03
53 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
54 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
55 INT214148 Binding of Lepr and Cartpt 1 0.09 0.21 0.03
56 INT184081 Binding of Irs4 and Socs6 1 0.11 0.2 0.03
57 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
58 INT228592 Pck1 Regulation of Positive_regulation of Gck 1 0.02 0.05 0
59 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
60 INT251071 Cldn3 Negative_regulation of Alms1 1 0.09 0.26 0
61 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
62 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
63 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
64 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
65 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0
66 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
67 INT86001 Binding of Pnp and Alms1 1 0.03 0 0
68 INT284391 Binding of AMT and Alms1 1 0.00 0 0
69 INT305884 Atp6v0a2 Regulation of Alms1 1 0.00 0 0
70 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
71 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
72 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0
73 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
74 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0
75 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
76 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
77 INT86004 Binding of PBCA and Alms1 1 0.01 0 0
78 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0
79 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
80 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
81 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
82 INT351623 APRT Positive_regulation of Pfkm 1 0.00 0.15 0
83 INT228589 G6pc Regulation of Positive_regulation of Gck 1 0.03 0.05 0
84 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
85 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0
86 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
87 INT235692 Clcn1 Positive_regulation of Binding of Alms1 1 0.05 0.9 0
88 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
89 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0
90 INT289523 Binding of Foxo1 and Positive_regulation of Sirt1 1 0.36 0.13 0
91 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
92 INT314132 Sirt1 Positive_regulation of Ppargc1a 1 0.50 2.3 0
93 INT299451 Foxl2 Negative_regulation of Gene_expression of Sirt1 1 0.25 0.32 0
94 INT289531 Acsm3 Positive_regulation of Sirt1 1 0.01 0.27 0
95 INT222547 Cartpt Positive_regulation of Localization of Prl 1 0.08 0 0
96 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
97 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0
98 INT305882 Binding of Pcx and Alms1 1 0.03 0.62 0
99 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0
100 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
101 INT289535 Negative_regulation of Sirt1 Negative_regulation of Binding of Foxo1 1 0.29 0.14 0
102 INT289529 Lep Regulation of Sirt1 1 0.28 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular glucose homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in cellular glucose homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
2 INT36177 Binding of Alms1 70 0.31 35.47 13.81
3 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
4 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
5 INT82984 Gene_expression of Cartpt 27 0.78 3.93 11.55
6 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
7 INT214106 Gene_expression of Cartpt 21 0.73 3.68 7.84
8 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
9 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
10 INT128069 Localization of Cartpt 6 0.81 0.65 4.75
11 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
12 INT32553 Regulation of Pfkm 7 0.62 0.64 3.89
13 INT108761 Localization of Alms1 24 0.70 13.92 3.74
14 INT253819 Negative_regulation of Cartpt 1 0.40 0.34 3.49
15 INT11202 Positive_regulation of Pfkm 8 0.57 1.74 3.06
16 INT35465 Negative_regulation of Pfkm 8 0.57 3.84 2.6
17 INT11201 Gene_expression of Pfkm 3 0.18 0.43 2.33
18 INT95621 Gene_expression of Gck 6 0.64 1.06 2.26
19 INT300587 Negative_regulation of Gene_expression of Cartpt 3 0.36 0.58 2.19
20 INT129871 Positive_regulation of Gene_expression of Gck 1 0.28 0.15 2.19
21 INT85464 Positive_regulation of Cartpt 5 0.70 0.62 2.18
22 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
23 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95
24 INT253822 Binding of Cartpt 1 0.35 0.16 1.92
25 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88
26 INT82983 Transcription of Cartpt 2 0.66 0.17 1.86
27 INT214096 Localization of Cartpt 3 0.76 0.62 1.8
28 INT214126 Negative_regulation of Gene_expression of Cartpt 5 0.35 0.66 1.57
29 INT104015 Regulation of Gene_expression of Pfkm 1 0.01 0 1.54
30 INT253814 Regulation of Cartpt 1 0.37 0.28 1.52
31 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
32 INT160619 Regulation of Cartpt 4 0.45 0.96 1.49
33 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
34 INT144152 Gene_expression of Socs6 2 0.39 0.19 1.16
35 INT105346 Gene_expression of Gck 5 0.71 3.05 1.14
36 INT92106 Localization of Socs6 2 0.16 1.54 1.1
37 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
38 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
39 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02
40 INT43145 Regulation of Regulation of Pfkm 1 0.45 0 0.97
41 INT135937 Positive_regulation of Positive_regulation of Cartpt 2 0.50 0.14 0.92
42 INT173514 Negative_regulation of Gene_expression of Alms1 3 0.06 3.49 0.91
43 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
44 INT230493 Regulation of Binding of Alms1 3 0.12 1.89 0.76
45 INT92107 Positive_regulation of Localization of Socs6 1 0.05 0.86 0.74
46 INT92104 Positive_regulation of Socs6 1 0.08 0.85 0.73
47 INT253817 Positive_regulation of Gene_expression of Cartpt 1 0.47 0.15 0.71
48 INT106573 Phosphorylation of Pfkm 1 0.43 0.1 0.64
49 INT253818 Negative_regulation of Localization of Cartpt 1 0.40 0 0.58
50 INT289903 Regulation of Localization of Alms1 2 0.14 1.48 0.56
51 INT253820 Positive_regulation of Binding of Cartpt 1 0.47 0 0.56
52 INT253812 Regulation of Gene_expression of Cartpt 1 0.43 0 0.55
53 INT320849 Binding of CARTPT 5 0.14 1.85 0.54
54 INT230495 Regulation of Gene_expression of Alms1 4 0.04 4.53 0.53
55 INT253821 Negative_regulation of Negative_regulation of Cartpt 1 0.35 0 0.52
56 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
57 INT354813 Positive_regulation of Negative_regulation of Alms1 1 0.04 0.82 0.48
58 INT242443 Positive_regulation of Localization of Alms1 2 0.09 0.66 0.46
59 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
60 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
61 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
62 INT253824 Positive_regulation of Cartpt 1 0.38 0.06 0.41
63 INT340755 Negative_regulation of CARTPT 2 0.30 2.08 0.4
64 INT308524 Regulation of Protein_catabolism of Alms1 1 0.06 1.04 0.4
65 INT105342 Positive_regulation of Gene_expression of Gck 2 0.46 0.83 0.36
66 INT105343 Negative_regulation of Gene_expression of Gck 1 0.39 0 0.36
67 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
68 INT105345 Localization of Gck 1 0.60 0 0.33
69 INT154243 Positive_regulation of Binding of Alms1 4 0.42 1.86 0.32
70 INT85466 Regulation of Transcription of Cartpt 1 0.27 0 0.32
71 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
72 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
73 INT105341 Regulation of Gck 1 0.25 0 0.3
74 INT300577 Regulation of Gene_expression of Cartpt 1 0.14 0.13 0.28
75 INT300603 Binding of Cartpt 1 0.10 0.08 0.28
76 INT243208 Negative_regulation of Protein_catabolism of Alms1 2 0.06 2.21 0.26
77 INT85465 Positive_regulation of Gene_expression of Cartpt 1 0.50 0 0.22
78 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
79 INT295891 Positive_regulation of Positive_regulation of Alms1 1 0.02 0.48 0.2
80 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19
81 INT35464 Positive_regulation of Positive_regulation of Pfkm 1 0.38 0.71 0.19
82 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
83 INT95619 Negative_regulation of Gck 3 0.39 0.88 0.16
84 INT11199 Positive_regulation of Gene_expression of Pfkm 1 0.12 0 0.15
85 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
86 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
87 INT150107 Negative_regulation of Gck 2 0.31 0.89 0.12
88 INT243206 Negative_regulation of Localization of Alms1 1 0.05 0.98 0.12
89 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
90 INT297431 Phosphorylation of Gck 2 0.54 0.29 0.11
91 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
92 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
93 INT269505 Binding of Socs6 1 0.02 1.02 0.1
94 INT289567 Regulation of Negative_regulation of Sirt1 1 0.45 0.74 0.09
95 INT348977 Positive_regulation of Negative_regulation of CARTPT 1 0.08 0.69 0.08
96 INT204332 Positive_regulation of PPARGC1A 7 0.67 1.42 0.07
97 INT289574 Negative_regulation of Positive_regulation of Sirt1 1 0.42 0.42 0.07
98 INT344823 Negative_regulation of Negative_regulation of Alms1 1 0.04 1.04 0.07
99 INT344812 Negative_regulation of Binding of Alms1 1 0.04 1.04 0.07
100 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
101 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
102 INT95623 Negative_regulation of Gene_expression of Gck 3 0.39 0.91 0.05
103 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
104 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
105 INT289587 Negative_regulation of Negative_regulation of Sirt1 1 0.42 0.65 0.05
106 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
107 INT240929 Positive_regulation of Gck 1 0.42 0 0.04
108 INT289584 Binding of Sirt1 3 0.48 1.35 0.03
109 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
110 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
111 INT231013 Protein_catabolism of Socs6 1 0.17 0.93 0.03
112 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
113 INT204349 Regulation of SIRT1 8 0.61 1.99 0
114 INT256134 Localization of Sirt1 5 0.50 2.99 0
115 INT204353 Transcription of SIRT1 3 0.68 0.67 0
116 INT204372 Transcription of PPARGC1A 3 0.67 0.28 0
117 INT228573 Transcription of Gck 2 0.26 0.05 0
118 INT228582 Positive_regulation of Gck 2 0.13 0.88 0
119 INT204346 Positive_regulation of Transcription of PPARGC1A 2 0.49 0.28 0
120 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0
121 INT289569 Transcription of Sirt1 1 0.71 0.25 0
122 INT239508 Transcription of Alms1 1 0.20 0 0
123 INT300686 Regulation of Binding of Sirt1 1 0.44 0.06 0
124 INT345441 Positive_regulation of Transcription of Gck 1 0.18 0 0
125 INT300287 Localization of Sirt1 1 0.66 1.46 0
126 INT204350 Negative_regulation of Transcription of PPARGC1A 1 0.41 0.1 0
127 INT345448 Binding of Gck 1 0.13 0 0
128 INT345449 Regulation of Transcription of Gck 1 0.16 0 0
129 INT256565 Regulation of Gene_expression of Gck 1 0.45 1.64 0
130 INT289583 Regulation of Transcription of Sirt1 1 0.27 0.25 0
131 INT204333 Regulation of PPARGC1A 1 0.26 0.34 0
132 INT348976 Positive_regulation of CARTPT 1 0.08 0.61 0
133 INT300683 Positive_regulation of Negative_regulation of Sirt1 1 0.45 0 0
134 INT204357 Positive_regulation of Positive_regulation of PPARGC1A 1 0.49 0.07 0
135 INT204371 Positive_regulation of Transcription of SIRT1 1 0.49 0.13 0
136 INT204347 Positive_regulation of Negative_regulation of PPARGC1A 1 0.49 0 0
137 INT204369 Negative_regulation of Positive_regulation of PPARGC1A 1 0.41 0.07 0
138 INT318239 Regulation of Transcription of SIRT1 1 0.26 0.45 0
139 INT320850 Positive_regulation of Binding of CARTPT 1 0.14 0.16 0
140 INT240932 Negative_regulation of Transcription of Sirt1 1 0.34 0.29 0
141 INT289594 Regulation of Regulation of Sirt1 1 0.45 0.15 0
142 INT350520 Phosphorylation of SIRT1 1 0.25 0.72 0
143 INT204356 Regulation of Gene_expression of SIRT1 1 0.61 0.29 0
144 INT204366 Positive_regulation of Gene_expression of PPARGC1A 1 0.67 1.44 0
145 INT204337 Regulation of Gene_expression of PPARGC1A 1 0.44 0.48 0
146 INT204339 Binding of PPARGC1A 1 0.35 0.19 0
147 INT204329 Positive_regulation of Regulation of PPARGC1A 1 0.45 0.07 0
148 INT204341 Negative_regulation of Gene_expression of PPARGC1A 1 0.41 0 0
149 INT204331 Binding of SIRT1 1 0.47 0.39 0
150 INT204351 Negative_regulation of PPARGC1A 1 0.42 0.25 0
151 INT300685 Positive_regulation of Binding of Sirt1 1 0.67 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox