GO:0001696

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Name gastric acid secretion
Categary Process
Go Slim No
Go Link GO:0001696
Unique Molecular Interactions 133
Total Molecular Interactions 218
Total Single Events 1067
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for gastric acid secretion. They are ordered first by their pain relevance and then by number of times they were reported for gastric acid secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
2 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
3 INT353717 Binding of Ghrl and Vta1 1 0.15 0 1.68
4 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
5 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
6 INT226128 Positive_regulation of Ghrl Regulation of Prkag1 1 0.06 0.28 0.97
7 INT89828 Atp4b Positive_regulation of Localization of Grip2 1 0.10 0.54 0.97
8 INT295530 Ghrl Regulation of Gene_expression of Ghrh 1 0.30 0.21 0.95
9 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92
10 INT295547 Ghrl Regulation of Ghrh 1 0.30 0.06 0.9
11 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88
12 INT137563 Ghrl Positive_regulation of Gene_expression of Npy 1 0.59 0 0.87
13 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84
14 INT295546 Ghrl Positive_regulation of Ghsr 3 0.39 0.09 0.77
15 INT226122 Ghrl Regulation of Cnr1 1 0.25 0.09 0.76
16 INT353716 Ghrl Positive_regulation of Vta1 1 0.33 0 0.74
17 INT353722 Rbm39 Positive_regulation of Localization of Ghrl 1 0.01 0 0.65
18 INT167139 Binding of Ghrl and Mln 1 0.04 0.56 0.65
19 INT105971 GH1 Regulation of Ghrl 1 0.03 0.75 0.52
20 INT110300 Cartpt Regulation of Adarb1 1 0.14 0 0.49
21 INT226125 Ghrl Positive_regulation of Cnr1 1 0.44 0.06 0.46
22 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45
23 INT349686 Nmu Positive_regulation of Nmur1 1 0.36 0.2 0.45
24 INT295548 Ghrl Regulation of Regulation of Ghrh 1 0.30 0 0.45
25 INT226126 Negative_regulation of Ghrl Regulation of Prkag1 1 0.06 0.17 0.45
26 INT118208 Ghrl Negative_regulation of Localization of Prl 1 0.39 0 0.44
27 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43
28 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43
29 INT226127 Regulation of Ghrl Regulation of Prkag1 1 0.05 0.07 0.42
30 INT295533 Ghrl Regulation of Npy 1 0.23 0.09 0.42
31 INT226116 Ghrl Regulation of Positive_regulation of Npy 1 0.17 0 0.41
32 INT134761 Ghrl Regulation of Localization of Tnf 1 0.20 0.76 0.4
33 INT226129 Ghrl Regulation of Localization of Prkag1 1 0.05 0.07 0.4
34 INT118210 Ghrl Negative_regulation of Prl 1 0.53 0 0.33
35 INT226124 Ghrl Positive_regulation of Prkag1 1 0.06 0.24 0.33
36 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33
37 INT137561 Ghrl Regulation of Gene_expression of Npy 1 0.53 0 0.32
38 INT168948 Binding of CCK and CCKAR 1 0.23 0 0.3
39 INT137386 Ghrl Regulation of Gene_expression of Pigm 1 0.00 0.36 0.3
40 INT188288 Ghrl Regulation of Gene_expression of Pou1f1 1 0.07 0 0.3
41 INT137385 Ghrl Negative_regulation of Gene_expression of Pigm 1 0.01 0.36 0.3
42 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29
43 INT295549 Ghrl Positive_regulation of Gene_expression of Ghsr 1 0.29 0 0.29
44 INT295526 Ghrl Positive_regulation of Gene_expression of Fos 1 0.41 0.08 0.29
45 INT157082 Ghrl Positive_regulation of Localization of Gh1 2 0.22 0.18 0.28
46 INT137562 Ghrl Positive_regulation of Gene_expression of Agrp 1 0.30 0 0.28
47 INT295531 Ghrl Negative_regulation of Gene_expression of Ghrh 1 0.25 0 0.27
48 INT157080 Ghrl Positive_regulation of Localization of Gnrhr 2 0.23 0.7 0.26
49 INT295541 Ghrl Positive_regulation of Ghrh 1 0.31 0 0.26
50 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25
51 INT118211 Ghrl Positive_regulation of Localization of Prl 1 0.63 0 0.24
52 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23
53 INT164251 Ghrl Negative_regulation of Localization of Gnrh1 1 0.34 0 0.22
54 INT352961 Ghrl Positive_regulation of Localization of GHSR 1 0.18 1.19 0.21
55 INT157083 Ghrl Regulation of Gene_expression of Ppt1 1 0.40 0 0.2
56 INT295542 Ghrl Positive_regulation of Gene_expression of Ghrh 1 0.33 0 0.19
57 INT325390 Binding of Ghrl and Gpr39 1 0.19 0 0.18
58 INT323494 Ghrl Regulation of Ins1 1 0.16 2.12 0.17
59 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17
60 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16
61 INT118209 Ghrl Regulation of Localization of Prl 1 0.56 0 0.15
62 INT172256 Binding of NMU and GPR87 1 0.31 0 0.14
63 INT172241 Binding of NMUR1 and NMU 1 0.40 0 0.14
64 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13
65 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13
66 INT295540 Binding of Gh and Ghrl 2 0.10 0.13 0.12
67 INT226132 Ghrl Positive_regulation of Gene_expression of Prkag1 1 0.06 0 0.12
68 INT226117 Ghrl Positive_regulation of Gene_expression of Mastl 1 0.02 0 0.12
69 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
70 INT295545 Ghrl Positive_regulation of Gh 1 0.15 0 0.11
71 INT295551 Ghrl Positive_regulation of Localization of Gh 1 0.15 0 0.1
72 INT293627 GHRL Positive_regulation of EDNRA 1 0.00 0.96 0.1
73 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1
74 INT222501 Cartpt Negative_regulation of Localization of Prl 1 0.08 0 0.1
75 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1
76 INT139250 CCKAR Positive_regulation of Localization of POMC 1 0.35 0.61 0.09
77 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
78 INT41574 POMC Regulation of CCKAR 1 0.00 0 0.09
79 INT143399 Binding of INSRR and NMU 1 0.01 0.12 0.09
80 INT157079 Ghrl Positive_regulation of Gnrhr 1 0.23 0 0.09
81 INT157081 Ghrl Positive_regulation of Gh1 1 0.22 0 0.09
82 INT295527 Gene_expression of Ghrl Positive_regulation of Gene_expression of Fos 1 0.29 0 0.09
83 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08
84 INT188291 Ghrl Regulation of Localization of LH 1 0.03 0 0.08
85 INT325418 Ghrl Positive_regulation of Ghsr 1 0.16 0 0.08
86 INT162762 Ghrl Regulation of Son 1 0.36 0 0.07
87 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07
88 INT323486 Ghrl Regulation of Localization of Ins1 1 0.21 2.07 0.07
89 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07
90 INT295550 Binding of Ghrh and Ghrl 1 0.21 0.06 0.07
91 INT295529 Ghrl Regulation of Localization of Gh 1 0.20 0 0.06
92 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05
93 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05
94 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05
95 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05
96 INT323482 Ghrl Negative_regulation of Ins1 1 0.13 0.24 0.05
97 INT229820 Fos Positive_regulation of Gene_expression of Ghrl 1 0.02 0.05 0.05
98 INT323503 STARD7 Positive_regulation of Ghrl 1 0.24 1.92 0.05
99 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05
100 INT323485 Ghrl Negative_regulation of Localization of Ins1 1 0.15 1.99 0.05
101 INT222498 Ghrh Positive_regulation of Gene_expression of Ghrl 1 0.10 0.19 0.04
102 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04
103 INT222497 Negative_regulation of Gh1 Negative_regulation of Ghrl 1 0.01 0.2 0.04
104 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04
105 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03
106 INT175560 Binding of GPER and GHRL 1 0.01 1.14 0.03
107 INT97896 Ghrl Positive_regulation of Localization of Gh 1 0.48 0.37 0.03
108 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03
109 INT28372 CPM Regulation of GHRL 2 0.05 0 0
110 INT222536 Ghrl Positive_regulation of Transcription of Pou1f1 1 0.03 0.13 0
111 INT188289 Ghrl Negative_regulation of Gnrh1 1 0.08 0.17 0
112 INT188295 Binding of KITLG and Ghrl 1 0.02 0.09 0
113 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0
114 INT28371 CPN2 Regulation of GHRL 1 0.00 0 0
115 INT323489 Ghrl Regulation of Regulation of Ins1 1 0.09 0.07 0
116 INT323493 Binding of Ins1 and Ghrl 1 0.12 1.25 0
117 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
118 INT323499 Ghrl Positive_regulation of Ins1 1 0.21 0.25 0
119 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0
120 INT163696 Ghrl Regulation of Efs 1 0.05 0 0
121 INT188292 Ghrl Regulation of Gnrhr 1 0.01 0.19 0
122 INT323500 Ghrl Positive_regulation of Grb2 1 0.13 0.5 0
123 INT323495 Ghrl Positive_regulation of Irs1 1 0.20 0.5 0
124 INT188287 Ghrl Regulation of Gh1 1 0.01 0.19 0
125 INT188293 Ghrl Negative_regulation of LH 1 0.03 0.17 0
126 INT188290 Ghrl Regulation of Gene_expression of Kitlg 1 0.02 0.15 0
127 INT323487 Ghrl Positive_regulation of Phosphorylation of Akt1 1 0.09 0.77 0
128 INT222537 Binding of Nmu and Hpse 1 0.01 0.15 0
129 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0
130 INT222547 Cartpt Positive_regulation of Localization of Prl 1 0.08 0 0
131 INT163697 Ghrl Regulation of Gene_expression of Efs 1 0.09 0 0
132 INT222419 Nmu Positive_regulation of Localization of Pomc 1 0.03 0.17 0
133 INT325420 Ghrl Regulation of Mag 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for gastric acid secretion. They are ordered first by their pain relevance and then by number of times they were reported in gastric acid secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61893 Gene_expression of Ghrl 125 0.75 71.49 15.14
2 INT14513 Localization of Ghrl 52 0.78 29.26 11.63
3 INT82984 Gene_expression of Cartpt 27 0.78 3.93 11.55
4 INT97891 Gene_expression of Ghrl 108 0.77 24.85 9.7
5 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68
6 INT224964 Localization of Ghrl 30 0.59 7.71 8.77
7 INT226106 Negative_regulation of Ghrl 12 0.40 3.98 5.39
8 INT23725 Gene_expression of CCKAR 14 0.55 0.14 5.3
9 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5
10 INT128069 Localization of Cartpt 6 0.81 0.65 4.75
11 INT141285 Positive_regulation of Localization of Ghrl 11 0.63 9.38 3.86
12 INT132317 Positive_regulation of Gene_expression of Ghrl 20 0.49 21 3.57
13 INT226114 Binding of Ghrl 18 0.36 4.34 3.54
14 INT23728 Negative_regulation of CCKAR 6 0.42 0.48 3.53
15 INT118207 Binding of Ghrl 11 0.47 7.39 3.52
16 INT85947 Regulation of Cckar 2 0.36 2.4 2.86
17 INT112093 Transcription of Nmu 2 0.68 1.09 2.8
18 INT35251 Regulation of Ghrl 21 0.60 8.26 2.6
19 INT132411 Positive_regulation of Ghrl 25 0.69 12.05 2.59
20 INT23534 Regulation of CCKAR 8 0.32 0.17 2.56
21 INT323469 Negative_regulation of Localization of Ghrl 4 0.29 0.4 2.49
22 INT40505 Positive_regulation of CCKAR 3 0.40 0 2.42
23 INT226105 Regulation of Ghrl 10 0.50 2.36 2.26
24 INT152538 Gene_expression of Nmu 7 0.74 1.12 2.25
25 INT30202 Positive_regulation of GHRL 5 0.44 3.04 2.22
26 INT300587 Negative_regulation of Gene_expression of Cartpt 3 0.36 0.58 2.19
27 INT85464 Positive_regulation of Cartpt 5 0.70 0.62 2.18
28 INT188282 Regulation of Gene_expression of Ghrl 16 0.31 10.08 1.95
29 INT164017 Negative_regulation of Localization of Ghrl 2 0.53 3.12 1.88
30 INT82983 Transcription of Cartpt 2 0.66 0.17 1.86
31 INT30373 Localization of CCKAR 5 0.68 0.17 1.79
32 INT4786 Gene_expression of GHRL 7 0.78 7.94 1.76
33 INT97892 Positive_regulation of Gene_expression of Ghrl 31 0.49 13.43 1.7
34 INT160619 Regulation of Cartpt 4 0.45 0.96 1.49
35 INT54775 Binding of Cckar 1 0.34 0 1.43
36 INT224947 Positive_regulation of Localization of Ghrl 3 0.34 0.48 1.4
37 INT168954 Binding of CCKAR 1 0.28 0 1.36
38 INT23727 Positive_regulation of Gene_expression of CCKAR 4 0.31 0 1.34
39 INT349696 Positive_regulation of Nmu 1 0.66 0 1.33
40 INT19388 Regulation of Nmu 2 0.61 0.25 1.28
41 INT161750 Transcription of Ghrl 14 0.67 7.05 1.23
42 INT323462 Regulation of Gene_expression of Ghrl 2 0.27 0.15 1
43 INT135937 Positive_regulation of Positive_regulation of Cartpt 2 0.50 0.14 0.92
44 INT349712 Regulation of Transcription of Nmu 1 0.43 0.32 0.92
45 INT23726 Positive_regulation of Negative_regulation of CCKAR 1 0.08 0 0.82
46 INT161751 Positive_regulation of Transcription of Ghrl 3 0.49 3.89 0.81
47 INT323980 Regulation of Localization of Ghrl 5 0.60 3.04 0.8
48 INT323979 Negative_regulation of Negative_regulation of Ghrl 2 0.42 0.98 0.76
49 INT23953 Gene_expression of Cckar 3 0.65 0.2 0.74
50 INT35926 Gene_expression of NMU 5 0.75 1.34 0.66
51 INT166886 Negative_regulation of Gene_expression of Ghrl 3 0.41 4.11 0.66
52 INT163329 Negative_regulation of GHRL 5 0.58 7.34 0.65
53 INT168965 Negative_regulation of Binding of CCKAR 1 0.22 0 0.63
54 INT168966 Positive_regulation of Localization of CCKAR 1 0.29 0 0.62
55 INT25006 Negative_regulation of Gene_expression of CCKAR 1 0.30 0 0.62
56 INT4783 Localization of GHRL 5 0.11 1.28 0.61
57 INT62101 Protein_catabolism of CCKAR 1 0.01 0 0.54
58 INT39113 Negative_regulation of Cckar 2 0.41 0.28 0.5
59 INT349710 Regulation of Gene_expression of Nmu 1 0.43 0 0.48
60 INT202229 Regulation of GHRL 3 0.07 1.8 0.47
61 INT4780 Positive_regulation of Gene_expression of GHRL 2 0.06 1.03 0.45
62 INT136414 Regulation of NMU 2 0.26 1.28 0.44
63 INT325380 Positive_regulation of Positive_regulation of Ghrl 2 0.45 1.35 0.35
64 INT137559 Negative_regulation of Regulation of Ghrl 1 0.32 0 0.34
65 INT349723 Positive_regulation of Transcription of Nmu 1 0.48 0 0.34
66 INT41640 Binding of GHRL 2 0.15 1.78 0.32
67 INT85466 Regulation of Transcription of Cartpt 1 0.27 0 0.32
68 INT349699 Positive_regulation of Gene_expression of Nmu 1 0.44 0 0.32
69 INT287775 Transcription of Ghrl 3 0.41 1.27 0.31
70 INT137851 Positive_regulation of Atp4b 1 0.01 0 0.3
71 INT295517 Negative_regulation of Gene_expression of Ghrl 2 0.32 0.91 0.28
72 INT300577 Regulation of Gene_expression of Cartpt 1 0.14 0.13 0.28
73 INT300603 Binding of Cartpt 1 0.10 0.08 0.28
74 INT35927 Positive_regulation of Gene_expression of NMU 2 0.67 0.17 0.26
75 INT295520 Regulation of Positive_regulation of Ghrl 1 0.24 0.16 0.26
76 INT112094 Negative_regulation of Nmu 1 0.42 0.23 0.22
77 INT85465 Positive_regulation of Gene_expression of Cartpt 1 0.50 0 0.22
78 INT30371 Regulation of Localization of CCKAR 1 0.18 0.17 0.22
79 INT10042 Protein_catabolism of Cckar 1 0.08 0 0.18
80 INT76880 Localization of Cckar 2 0.07 0.08 0.17
81 INT121057 Binding of Nmu 1 0.36 0.23 0.17
82 INT325379 Regulation of Positive_regulation of Ghrl 1 0.26 0.23 0.17
83 INT293628 Regulation of Transcription of Ghrl 1 0.31 0.96 0.13
84 INT293629 Negative_regulation of Gene_expression of GHRL 1 0.02 0.79 0.13
85 INT323468 Negative_regulation of Negative_regulation of Ghrl 1 0.21 0.14 0.12
86 INT131055 Positive_regulation of Cckar 1 0.36 0 0.09
87 INT328361 Positive_regulation of Negative_regulation of Ghrl 1 0.24 0.12 0.07
88 INT323466 Negative_regulation of Binding of Ghrl 1 0.21 0.36 0.07
89 INT287774 Negative_regulation of Transcription of Ghrl 1 0.02 1.28 0.05
90 INT302734 Negative_regulation of Positive_regulation of Ghrl 2 0.41 1.58 0.04
91 INT226110 Positive_regulation of Binding of Ghrl 1 0.30 0 0.04
92 INT323471 Regulation of Localization of Ghrl 1 0.22 0 0.04
93 INT293630 Regulation of Gene_expression of GHRL 1 0.01 0.54 0.03
94 INT293631 Negative_regulation of Positive_regulation of GHRL 1 0.02 0.89 0.03
95 INT323464 Phosphorylation of Ghrl 1 0.40 0.19 0.03
96 INT222614 Negative_regulation of Gene_expression of Nmu 1 0.14 0.18 0
97 INT328291 Protein_catabolism of Ghrl 1 0.13 0.17 0
98 INT328352 Protein_catabolism of Ghrl 1 0.86 0.15 0
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