GO:0001701

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Name in utero embryonic development
Categary Process
Go Slim No
Go Link GO:0001701
Unique Molecular Interactions 2736
Total Molecular Interactions 3740
Total Single Events 28410
Pain Genes Associated 220

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for in utero embryonic development. They are ordered first by their pain relevance and then by number of times they were reported for in utero embryonic development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
3 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
4 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
5 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
6 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
7 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
8 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
9 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
10 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
11 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
12 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
13 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
14 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
15 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
16 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
17 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
18 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
19 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
20 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
21 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
22 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
23 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
24 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
25 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
26 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
27 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
28 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
29 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
30 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
31 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
32 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
33 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
34 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
35 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
36 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
37 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
38 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
39 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
40 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
41 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
42 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
43 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
44 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
45 INT1619 Binding of Gad1 and Oprl1 1 0.14 0 1.13
46 INT1620 Negative_regulation of Binding of Gad1 and Oprl1 1 0.16 0 1.13
47 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
48 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
49 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
50 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
51 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
52 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
53 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
54 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
55 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
56 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
57 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
58 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
59 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
60 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
61 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
62 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
63 INT250085 Coq7 Positive_regulation of Ltp 1 0.00 0.52 1
64 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
65 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
66 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
67 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
68 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
69 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
70 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98
71 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
72 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
73 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
74 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
75 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
76 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
77 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
78 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
79 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
80 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
81 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
82 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
83 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
84 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
85 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
86 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
87 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
88 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
89 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
90 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
91 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
92 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
93 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
94 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
95 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
96 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
97 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
98 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
99 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
100 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
101 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
102 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
103 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
104 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
105 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
106 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
107 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
108 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
109 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
110 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
111 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
112 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
113 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
114 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
115 INT12137 Ngf Regulation of Gad1 1 0.27 0.67 0.83
116 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
117 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
118 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
119 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
120 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
121 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
122 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
123 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
124 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
125 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
126 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
127 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
128 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
129 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
130 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
131 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
132 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
133 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
134 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
135 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
136 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
137 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
138 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
139 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
140 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
141 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
142 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
143 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
144 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
145 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
146 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
147 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
148 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
149 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
150 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73
151 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
152 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
153 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
154 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
155 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
156 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
157 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
158 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
159 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
160 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
161 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
162 INT326457 Runx1 Regulation of Mrgpra3 1 0.37 0.1 0.71
163 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
164 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
165 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
166 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
167 INT326456 Runx1 Regulation of Pip4k2b 1 0.09 0.11 0.71
168 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
169 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
170 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
171 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
172 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
173 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
174 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
175 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
176 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
177 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
178 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
179 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
180 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
181 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
182 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
183 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
184 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
185 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
186 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67
187 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
188 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
189 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
190 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
191 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
192 INT89875 Pdyn Positive_regulation of Localization of Myh6 1 0.09 0 0.66
193 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
194 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
195 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
196 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
197 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
198 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
199 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
200 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63

Single Events

The table below shows the top 100 pain related interactions that have been reported for in utero embryonic development. They are ordered first by their pain relevance and then by number of times they were reported in in utero embryonic development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
3 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
4 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
5 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
6 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
7 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
8 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
9 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
10 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
11 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
12 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
13 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71
14 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
15 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
16 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
17 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
18 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
19 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
20 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
21 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9
22 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
23 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
24 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
25 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
26 INT1616 Regulation of Gad1 46 0.61 10.2 28.64
27 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
28 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
29 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
30 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
31 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
32 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
33 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
34 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
35 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
36 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
37 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
38 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
39 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
40 INT16326 Transcription of Gad1 58 0.71 15.78 20.45
41 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
42 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
43 INT5048 Binding of Edn1 55 0.47 18.86 19.16
44 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
45 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
46 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
47 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
48 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
49 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
50 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
51 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
52 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
53 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
54 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
55 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4
56 INT41558 Localization of Sp1 9 0.48 0.56 14.9
57 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
58 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
59 INT9191 Localization of EDN1 94 0.81 57.01 14.78
60 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
61 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
62 INT6365 Localization of Edn1 56 0.81 18.84 13.83
63 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
64 INT173505 Localization of Hand2 63 0.57 45.32 13.66
65 INT20378 Localization of Hand1 53 0.71 41.96 13.31
66 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
67 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
68 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
69 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
70 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
71 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
72 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
73 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42
74 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39
75 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
76 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08
77 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
78 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
79 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
80 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
81 INT138639 Gene_expression of Hcn4 32 0.75 13.85 11.25
82 INT171253 Positive_regulation of BMI1 23 0.53 39.41 11.23
83 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
84 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
85 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88
86 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
87 INT133210 Positive_regulation of Runx1 33 0.69 18.25 10.12
88 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
89 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
90 INT245538 Negative_regulation of Gene_expression of Runx1 20 0.58 11.68 9.97
91 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
92 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
93 INT6361 Localization of Edn1 30 0.81 19.09 9.7
94 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
95 INT336 Negative_regulation of Gad1 19 0.58 7.71 9.51
96 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
97 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
98 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
99 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
100 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
101 INT26789 Positive_regulation of Gene_expression of Gad1 22 0.70 7.39 9.02
102 INT35366 Binding of AR 87 0.47 30.52 8.9
103 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
104 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
105 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
106 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
107 INT10237 Binding of EDN1 40 0.48 16 8.48
108 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
109 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
110 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
111 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
112 INT165228 Binding of BMI1 13 0.47 25.36 7.97
113 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
114 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
115 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
116 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
117 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
118 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
119 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
120 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
121 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
122 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
123 INT9478 Positive_regulation of Gene_expression of Junb 19 0.70 2.34 7.41
124 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
125 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
126 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
127 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
128 INT167049 Binding of Ednra 3 0.07 3.47 6.84
129 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
130 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
131 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
132 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
133 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
134 INT169596 Transcription of Runx1 12 0.71 5.55 6.27
135 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
136 INT245515 Regulation of Runx1 14 0.61 5.07 6.22
137 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
138 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
139 INT49011 Regulation of Gene_expression of Gad1 10 0.62 0.55 6.07
140 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
141 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
142 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
143 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
144 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
145 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
146 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
147 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
148 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
149 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
150 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
151 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
152 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
153 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
154 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
155 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
156 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
157 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
158 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
159 INT60585 Regulation of TP53 59 0.59 54.55 5.21
160 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
161 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
162 INT36256 Regulation of Ada 9 0.62 4.99 5.07
163 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06
164 INT99091 Regulation of AR 70 0.45 31.68 5.05
165 INT141275 Negative_regulation of Gene_expression of Hand1 18 0.34 15.83 5.05
166 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
167 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
168 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
169 INT131152 Gene_expression of Cr1l 17 0.75 10.83 4.88
170 INT245536 Regulation of Gene_expression of Runx1 11 0.58 6.22 4.88
171 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81
172 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
173 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
174 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
175 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
176 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
177 INT66388 Positive_regulation of Transcription of Gad1 14 0.67 2.45 4.67
178 INT246315 Localization of Ednra 22 0.15 2.73 4.64
179 INT5205 Localization of AR 43 0.80 12.87 4.63
180 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
181 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
182 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
183 INT21953 Binding of Ednra 12 0.33 4.72 4.56
184 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
185 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
186 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
187 INT198736 Binding of Sp3 23 0.40 4.77 4.42
188 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
189 INT30031 Gene_expression of Hba-a1 7 0.60 7.46 4.41
190 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
191 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
192 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
193 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
194 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
195 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
196 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
197 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
198 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
199 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
200 INT171252 Gene_expression of BMI1 21 0.70 26.98 4.11
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