GO:0001714

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Name endodermal cell fate specification
Categary Process
Go Slim No
Go Link GO:0001714
Unique Molecular Interactions 41
Total Molecular Interactions 56
Total Single Events 627
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endodermal cell fate specification. They are ordered first by their pain relevance and then by number of times they were reported for endodermal cell fate specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
2 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37
3 INT26669 Nanog Regulation of Binding of Tlyr1 1 0.02 0 0.28
4 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 0.20 0.42 0.19
5 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 0.40 0.9 0.07
6 INT201172 Sox2 Positive_regulation of Localization of Ca2 1 0.47 0.9 0.07
7 INT282552 POU5F1 Positive_regulation of FGF4 1 0.29 0.29 0.05
8 INT213562 Ctnnd2 Regulation of Gene_expression of Sox2 1 0.35 0.07 0.05
9 INT282555 POU5F1 Positive_regulation of Positive_regulation of MAPK1 1 0.11 0.28 0.04
10 INT282556 POU5F1 Positive_regulation of GOPC 1 0.06 0.06 0.04
11 INT285936 IL17A Positive_regulation of Gene_expression of POU5F1 1 0.10 0.34 0.04
12 INT282561 POU5F1 Positive_regulation of Gene_expression of NANOG 1 0.11 0.26 0.04
13 INT282543 KDM4C Regulation of POU5F1 1 0.06 0.08 0.03
14 INT282542 KDM3A Regulation of POU5F1 1 0.06 0.08 0.03
15 INT282553 POU5F1 Positive_regulation of REXO1 1 0.21 0.1 0.03
16 INT282559 NANOG Regulation of POU5F1 1 0.14 0.45 0
17 INT282557 NANOG Regulation of REXO1 1 0.07 0.23 0
18 INT282554 Binding of POU5F1 and SOX2 1 0.19 0.1 0
19 INT282551 SOX2 Regulation of POU5F1 1 0.24 0.45 0
20 INT282541 SOX2 Regulation of Transcription of POU5F1 1 0.24 0.05 0
21 INT282558 POU5F1 Positive_regulation of MAPK1 1 0.16 0.26 0
22 INT282547 SOX2 Regulation of REXO1 1 0.12 0.23 0
23 INT282607 POU5F1 Positive_regulation of Mdk 1 0.08 0.26 0
24 INT285946 IL6 Regulation of POU5F1 1 0.05 0.12 0
25 INT190427 NANOG Regulation of SOX2 1 0.11 0.16 0
26 INT282545 SOX2 Regulation of Gene_expression of NANOG 1 0.10 0 0
27 INT282549 POU5F1 Regulation of Transcription of SOX2 1 0.32 0.05 0
28 INT262942 Binding of PAX6 and SOX2 1 0.18 0.9 0
29 INT282539 POU5F1 Regulation of Gene_expression of NANOG 1 0.17 0 0
30 INT262943 Regulation of Binding of PAX6 and SOX2 1 0.17 0.91 0
31 INT190426 SOX2 Regulation of NANOG 1 0.11 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for endodermal cell fate specification. They are ordered first by their pain relevance and then by number of times they were reported in endodermal cell fate specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
2 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
3 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34
4 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
5 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
6 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
7 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
8 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
9 INT62692 Localization of Nanog 3 0.73 0.82 1.85
10 INT282590 Positive_regulation of Gene_expression of POU5F1 40 0.70 8.42 1.32
11 INT143759 Gene_expression of SOX2 46 0.55 11.12 1.24
12 INT282572 Positive_regulation of POU5F1 24 0.70 5.8 1.13
13 INT304863 Negative_regulation of Gene_expression of Nanog 4 0.41 0.91 0.84
14 INT282599 Regulation of Gene_expression of POU5F1 10 0.62 4.89 0.71
15 INT54497 Binding of Nanog 1 0.35 0 0.67
16 INT62732 Positive_regulation of Gene_expression of Nanog 2 0.45 0.27 0.63
17 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
18 INT230634 Negative_regulation of POU5F1 10 0.43 1.03 0.46
19 INT304861 Regulation of Gene_expression of Nanog 3 0.43 0.13 0.46
20 INT185255 Positive_regulation of Sox2 3 0.26 1.22 0.42
21 INT84326 Protein_catabolism of Nanog 1 0.02 0 0.41
22 INT190451 Gene_expression of NANOG 33 0.59 3.28 0.29
23 INT282571 Negative_regulation of Positive_regulation of POU5F1 1 0.38 0 0.28
24 INT201143 Regulation of Sox2 6 0.44 2.71 0.26
25 INT310483 Positive_regulation of Eomes 2 0.38 0.85 0.19
26 INT310478 Positive_regulation of Transcription of Eomes 1 0.23 0.42 0.19
27 INT310466 Positive_regulation of Positive_regulation of Eomes 1 0.23 0.42 0.19
28 INT170390 Transcription of Eomes 2 0.31 0.51 0.18
29 INT190454 Regulation of NANOG 2 0.30 1.29 0.17
30 INT282576 Negative_regulation of Gene_expression of POU5F1 12 0.43 2.79 0.16
31 INT310481 Regulation of Eomes 1 0.28 0.1 0.15
32 INT190458 Positive_regulation of Gene_expression of NANOG 4 0.35 0.75 0.14
33 INT278790 Binding of POU5F1 8 0.43 0.67 0.11
34 INT190447 Transcription of SOX2 5 0.36 0.84 0.11
35 INT201144 Regulation of Gene_expression of Sox2 3 0.44 0.82 0.11
36 INT201140 Transcription of Sox2 4 0.67 1.31 0.1
37 INT190456 Positive_regulation of SOX2 6 0.35 2.94 0.09
38 INT190445 Positive_regulation of NANOG 6 0.52 0.58 0.09
39 INT282591 Positive_regulation of Gene_expression of SOX2 4 0.36 1.07 0.08
40 INT190448 Transcription of NANOG 1 0.47 0 0.08
41 INT190452 Negative_regulation of Gene_expression of SOX2 4 0.27 1.61 0.07
42 INT278785 Positive_regulation of Binding of POU5F1 2 0.45 0.19 0.07
43 INT282954 Negative_regulation of NANOG 1 0.14 0.05 0.07
44 INT216377 Transcription of POU5F1 9 0.69 0.58 0.05
45 INT185260 Positive_regulation of Positive_regulation of Sox2 1 0.15 0 0.05
46 INT282603 Positive_regulation of Positive_regulation of POU5F1 1 0.45 0 0.05
47 INT213537 Positive_regulation of Gene_expression of Sox2 3 0.48 1.34 0.04
48 INT213528 Negative_regulation of Gene_expression of Sox2 1 0.30 0.07 0.04
49 INT282578 Negative_regulation of Positive_regulation of SOX2 1 0.22 0.05 0.04
50 INT170377 Gene_expression of Eomes 2 0.42 0.37 0.03
51 INT282944 Negative_regulation of Negative_regulation of POU5F1 1 0.11 0 0.03
52 INT190450 Negative_regulation of Gene_expression of NANOG 1 0.44 0 0.03
53 INT282597 Regulation of SOX2 1 0.31 0.14 0.03
54 INT336415 Positive_regulation of Gene_expression of Eomes 1 0.38 0.17 0.03
55 INT190460 Regulation of Gene_expression of NANOG 1 0.34 0 0.03
56 INT282948 Negative_regulation of Negative_regulation of NANOG 1 0.11 0 0.03
57 INT282605 Regulation of POU5F1 4 0.55 0.4 0
58 INT201142 Negative_regulation of Sox2 4 0.57 0.59 0
59 INT201141 Binding of Sox2 3 0.36 0.53 0
60 INT282585 Localization of POU5F1 3 0.67 0.08 0
61 INT339594 Localization of SOX2 2 0.69 0.7 0
62 INT336412 Negative_regulation of Gene_expression of Eomes 1 0.23 0.11 0
63 INT278808 Regulation of Binding of POU5F1 1 0.01 0 0
64 INT309646 Negative_regulation of Transcription of POU5F1 1 0.43 0 0
65 INT294844 Negative_regulation of SOX2 1 0.15 0.49 0
66 INT190461 Localization of NANOG 1 0.49 0.15 0
67 INT294843 Phosphorylation of NANOG 1 0.08 0.54 0
68 INT201146 Negative_regulation of Binding of Sox2 1 0.41 0.28 0
69 INT282582 Binding of SOX2 1 0.24 0.11 0
70 INT294842 Positive_regulation of Negative_regulation of POU5F1 1 0.41 0.49 0
71 INT201139 Localization of Sox2 1 0.73 0.15 0
72 INT294845 Positive_regulation of Negative_regulation of SOX2 1 0.18 0.49 0
73 INT336413 Negative_regulation of Eomes 1 0.32 0.11 0
74 INT284880 Binding of Eomes 1 0.03 0 0
75 INT190455 Positive_regulation of Transcription of NANOG 1 0.35 0 0
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