GO:0001726

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Name ruffle
Categary Component
Go Slim No
Go Link GO:0001726
Unique Molecular Interactions 369
Total Molecular Interactions 513
Total Single Events 4020
Pain Genes Associated 70

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ruffle. They are ordered first by their pain relevance and then by number of times they were reported for ruffle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
2 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
3 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
4 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
5 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
6 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
7 INT76378 Binding of Cit and Flvcr2 1 0.09 0.17 1.15
8 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
9 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
10 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
11 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
12 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8
13 INT152867 HTR1A Negative_regulation of Localization of S100b 1 0.46 0 0.75
14 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
15 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
16 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71
17 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
18 INT282664 Binding of Aif1 and Gfap 1 0.06 0 0.69
19 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
20 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
21 INT346412 Binding of Tesc and Sv2a 1 0.02 0.6 0.59
22 INT76379 Negative_regulation of Binding of Cit and Flvcr2 1 0.11 0.08 0.58
23 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
24 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
25 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57
26 INT76377 Regulation of Binding of Cit and Flvcr2 1 0.07 0.09 0.57
27 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
28 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
29 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
30 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
31 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
32 INT306936 Binding of Tnfsf12 and Tnfrsf12a 1 0.05 4.84 0.45
33 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
34 INT354235 Aif1 Regulation of P2ry12 1 0.20 0.49 0.45
35 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 0.02 0 0.44
36 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
37 INT168132 Binding of Yy1 and Tln2 1 0.01 0 0.43
38 INT346416 Binding of Tesc and Svs1 1 0.00 0.07 0.42
39 INT269448 HHIP Positive_regulation of Binding of RAB5A 1 0.04 0 0.42
40 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
41 INT110744 Faah Positive_regulation of Positive_regulation of Aif1 1 0.10 0.36 0.4
42 INT345006 CSF2 Regulation of GSN 1 0.16 0.82 0.39
43 INT118919 Binding of FRTS and Sh2b2 1 0.24 0 0.39
44 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
45 INT269456 RAB5A Regulation of Binding of HHIP 1 0.04 0 0.38
46 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37
47 INT129769 Binding of LYZ and S100B 1 0.33 0.86 0.37
48 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
49 INT345012 GSN Regulation of CCBE1 1 0.00 0.82 0.36
50 INT345010 GSN Regulation of DBP 1 0.26 0.81 0.36
51 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
52 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
53 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
54 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
55 INT254391 Binding of F13A1 and GSN 1 0.00 1.08 0.34
56 INT254393 Binding of FN1 and GSN 1 0.01 1.08 0.34
57 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
58 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
59 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
60 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33
61 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31
62 INT175017 Negative_regulation of Binding of REN and S100A6 1 0.13 0.45 0.29
63 INT175018 Positive_regulation of Binding of REN and S100A6 1 0.15 0.45 0.29
64 INT44091 Binding of ACTN1 and CAMSAP2 1 0.08 0 0.28
65 INT213798 Sh2b2 Regulation of tf 1 0.12 0.53 0.27
66 INT213799 Sh2b2 Regulation of Tfeb 1 0.26 0.54 0.27
67 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27
68 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
69 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
70 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
71 INT345008 Binding of ACTN1 and CSF2 1 0.02 0.53 0.26
72 INT312726 AASS Positive_regulation of FGD1 1 0.02 0.08 0.24
73 INT101312 Samhd1 Positive_regulation of Gene_expression of Aif1 1 0.03 0.38 0.23
74 INT208084 Tlr4 Positive_regulation of Eps8l1 1 0.00 0.5 0.23
75 INT346409 Negative_regulation of Binding of mn and Tesc 1 0.00 0.29 0.22
76 INT285639 Col3a1 Regulation of Tnfrsf12a 1 0.19 0.16 0.22
77 INT285640 Eln Regulation of Tnfrsf12a 1 0.14 0.16 0.22
78 INT346408 Binding of mn and Tesc 1 0.00 0.29 0.22
79 INT266405 S100b Positive_regulation of Gene_expression of TFAM 1 0.00 1.02 0.21
80 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21
81 INT213812 Sh2b2 Positive_regulation of Tfeb 1 0.44 0.45 0.2
82 INT257398 Binding of FGD1 and GHRH 1 0.03 0.27 0.2
83 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
84 INT110745 Bphl Positive_regulation of Positive_regulation of Aif1 1 0.03 0.18 0.2
85 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
86 INT326390 Binding of PROC and Ezr 1 0.00 1 0.17
87 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
88 INT316123 Binding of HLA-DRA and BCAR1 1 0.02 0.48 0.16
89 INT148563 Ngf Positive_regulation of GNAS 1 0.06 0.07 0.16
90 INT269450 Binding of RAB5A and ISM2 1 0.00 0 0.16
91 INT208083 Binding of Arid3b and Eps8l1 1 0.01 0.4 0.16
92 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16
93 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
94 INT254392 Binding of CRP and GSN 1 0.12 0.33 0.16
95 INT143505 Aif1 Positive_regulation of CETN1 1 0.01 0.35 0.16
96 INT211311 Trav6-3 Positive_regulation of Gene_expression of Lcp1 1 0.13 0.2 0.15
97 INT346414 Thy1 Positive_regulation of Binding of Tesc 1 0.00 0.16 0.15
98 INT269451 Negative_regulation of Binding of RAB5A and HHIP 1 0.03 0 0.15
99 INT325952 Gene_expression of Ezr Positive_regulation of Mapk1 1 0.02 1.69 0.15
100 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
101 INT269452 RAB5A Regulation of Localization of HHIP 1 0.04 0 0.15
102 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
103 INT346410 Binding of Caprin1 and Tesc 1 0.00 0.17 0.14
104 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
105 INT287262 Binding of Cyth3 and Shbdp1 1 0.00 0.15 0.14
106 INT326379 Binding of Ezr and Slc9a3r2 2 0.03 0.34 0.13
107 INT96590 Mog Regulation of S100B 1 0.32 0.97 0.13
108 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
109 INT261381 Nsdhl Regulation of Gene_expression of S100b 1 0.06 0.82 0.13
110 INT237442 Ass1 Positive_regulation of S100b 1 0.00 0.18 0.13
111 INT330800 Binding of S100A1 and S100B 1 0.32 0.5 0.13
112 INT269445 Localization of HHIP Regulation of Gene_expression of RAB5A 1 0.03 0 0.13
113 INT269457 RAB5A Regulation of Regulation of HHIP 1 0.02 0 0.13
114 INT96589 Mbp Regulation of S100B 1 0.34 0.97 0.13
115 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13
116 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
117 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12
118 INT269491 Racgap1 Negative_regulation of RAB5A 1 0.01 0 0.12
119 INT326380 Binding of Cxcr4 and Podxl 1 0.05 0.36 0.12
120 INT345011 Binding of GSN and PTAFR 1 0.09 0.83 0.12
121 INT207112 Sh2b2 Positive_regulation of Phosphorylation of Akt2 1 0.68 0.24 0.12
122 INT101310 Samhd1 Positive_regulation of Gene_expression of Aif1 1 0.04 0.19 0.12
123 INT207115 Sh2b2 Positive_regulation of Akt2 1 0.49 0.24 0.12
124 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
125 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
126 INT27814 CD2AP Positive_regulation of PADI1 1 0.19 0.06 0.11
127 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
128 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11
129 INT255811 Binding of GNAS and MAPT 1 0.00 0.67 0.11
130 INT27815 Regulation of CD2AP Positive_regulation of PADI1 1 0.11 0.06 0.11
131 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
132 INT269458 HHIP Regulation of Gene_expression of RAB5A 1 0.04 0 0.1
133 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1
134 INT352303 Binding of AIF1 and CD68 1 0.01 0.71 0.1
135 INT272389 Bcar1 Negative_regulation of Gene_expression of Trpv6 1 0.01 0 0.1
136 INT303166 Binding of Dlgap1 and Psd 1 0.08 0.31 0.1
137 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09
138 INT137395 Binding of CD99 and S100B 1 0.17 1.04 0.09
139 INT255289 Snap25 Regulation of Gene_expression of Gnas 1 0.00 0 0.09
140 INT269460 ISM2 Positive_regulation of Binding of RAB5A 1 0.00 0 0.09
141 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
142 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
143 INT191814 PDLIM7 Positive_regulation of TNFRSF8 1 0.08 1.16 0.08
144 INT180200 Binding of BCAR1 and MMVP1 1 0.11 8.57 0.08
145 INT191813 PDLIM7 Positive_regulation of FUT4 1 0.09 1.16 0.08
146 INT284303 Mir155 Negative_regulation of Gnas 1 0.00 0.49 0.08
147 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
148 INT20957 Binding of Pak1 and Pak2 1 0.27 0.65 0.08
149 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
150 INT316112 Binding of S100B and SAE1 1 0.05 1.5 0.08
151 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08
152 INT159852 Gene_expression of IL2 Regulation of Gene_expression of ACTN1 1 0.03 0.16 0.07
153 INT266389 Binding of C2 and S100a6 1 0.04 0.5 0.07
154 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
155 INT231676 Binding of CD47 and ITGA5 1 0.02 0.08 0.07
156 INT325954 Binding of Cttn and Ezr 1 0.22 1.61 0.07
157 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
158 INT333243 Gene_expression of Cxcl12 Negative_regulation of Bcar1 1 0.15 1 0.07
159 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
160 INT267000 Mdk Negative_regulation of Positive_regulation of Baiap2 1 0.03 0.1 0.06
161 INT246441 Ccl5 Positive_regulation of Gene_expression of Aif1 1 0.03 0.71 0.06
162 INT246436 Ccl5 Regulation of Aif1 1 0.01 0.67 0.06
163 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06
164 INT326377 Ezr Positive_regulation of Positive_regulation of Rhoa 1 0.05 0.16 0.06
165 INT196125 Trpm7 Negative_regulation of Gene_expression of Trpc3 1 0.35 0.08 0.06
166 INT267040 Negative_regulation of NOS1 Negative_regulation of Positive_regulation of Baiap2 1 0.02 0.1 0.06
167 INT167271 Binding of Ezr and Clic5 1 0.54 0.07 0.06
168 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
169 INT326378 Binding of Rhoa and Ezr 1 0.04 0.17 0.06
170 INT196135 Trpm7 Negative_regulation of Trpc3 1 0.35 0.08 0.06
171 INT196131 Trpm7 Negative_regulation of Trpv4 1 0.14 0.08 0.06
172 INT196129 Trpm7 Negative_regulation of Gene_expression of Trpv4 1 0.32 0.08 0.06
173 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
174 INT317416 Binding of FN1 and ITGB1 1 0.47 0.69 0.05
175 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
176 INT237351 Binding of Mtm1 and Gopc 1 0.19 0.17 0.05
177 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
178 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05
179 INT173477 Bcar1 Regulation of Localization of Ins1 1 0.16 0.07 0.05
180 INT194688 PAK1 Positive_regulation of GADD45A 1 0.11 0 0.05
181 INT316109 TEAD1 Regulation of S100B 1 0.00 1.16 0.04
182 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
183 INT346418 Sv2a Positive_regulation of Binding of Tesc 1 0.02 0.1 0.04
184 INT263377 Abl1 Regulation of Src 1 0.15 0 0.04
185 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04
186 INT225230 Ad Positive_regulation of Nf2 1 0.04 1.37 0.04
187 INT345182 Binding of Lpar1 and Gsn 1 0.04 0 0.04
188 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04
189 INT263428 Abl1 Regulation of Pdgfra 1 0.00 0 0.04
190 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
191 INT263432 Trib3 Regulation of Abl1 1 0.00 0 0.04
192 INT263379 Abl1 Regulation of Bmx 1 0.04 0 0.04
193 INT204247 S100B Regulation of CD68 1 0.03 1.05 0.04
194 INT346407 Negative_regulation of Binding of Tesc and Sv2a 1 0.02 0 0.03
195 INT303248 LILRA3 Positive_regulation of Protein_catabolism of Psd 1 0.01 0.2 0.03
196 INT269453 HHIP Positive_regulation of RAB5A 1 0.04 0 0.03
197 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03
198 INT287234 PDLIM7 Positive_regulation of Gene_expression of BMP7 1 0.14 0.12 0.03
199 INT194707 RAC1 Positive_regulation of PAK1 1 0.01 0 0.03
200 INT194738 Binding of PAK1 and RAC1 1 0.01 0 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for ruffle. They are ordered first by their pain relevance and then by number of times they were reported in ruffle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68
2 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4
3 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
4 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
5 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17
6 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03
7 INT75684 Regulation of Aif1 32 0.47 8.03 7.89
8 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
9 INT189230 Gene_expression of GSN 12 0.75 25.04 7.6
10 INT112986 Positive_regulation of S100b 19 0.70 17.61 6.86
11 INT79770 Regulation of Gene_expression of Aif1 13 0.45 5.28 6.82
12 INT117299 Localization of S100b 19 0.78 1.58 6.8
13 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
14 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
15 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
16 INT38595 Localization of BCAR1 8 0.73 2.9 6.25
17 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2
18 INT254400 Negative_regulation of GSN 22 0.57 18.15 5.89
19 INT43524 Positive_regulation of Sh2b2 16 0.58 2.95 5.78
20 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
21 INT89959 Positive_regulation of Gene_expression of Aif1 14 0.58 7.44 5.05
22 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
23 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
24 INT269476 Binding of RAB5A 1 0.41 0 4.76
25 INT79767 Negative_regulation of Aif1 30 0.42 5.14 4.73
26 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
27 INT17742 Localization of S100B 44 0.80 17.14 4.65
28 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59
29 INT79768 Negative_regulation of Gene_expression of Aif1 8 0.58 5.15 4.52
30 INT98357 Binding of Gnas 11 0.41 1.87 4.35
31 INT34184 Localization of FGD1 7 0.65 2.68 4.21
32 INT58875 Positive_regulation of FGD1 20 0.60 3.88 4.19
33 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
34 INT325930 Gene_expression of Ezr 75 0.77 59.77 4.06
35 INT101301 Gene_expression of Aif1 17 0.42 16.43 4.06
36 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
37 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02
38 INT26368 Positive_regulation of S100A6 30 0.45 9.72 3.89
39 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81
40 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8
41 INT57397 Binding of Aif1 15 0.28 4.06 3.49
42 INT48292 Negative_regulation of Sh2b2 9 0.26 2.14 3.26
43 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23
44 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
45 INT346398 Binding of Tesc 1 0.02 1.88 3.14
46 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08
47 INT38594 Positive_regulation of Localization of BCAR1 3 0.63 0.44 3.07
48 INT115348 Localization of Baiap2 1 0.68 1.76 2.99
49 INT61714 Binding of FGD1 12 0.35 7.72 2.91
50 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
51 INT131929 Positive_regulation of Gene_expression of S100B 25 0.67 12.61 2.83
52 INT158083 Gene_expression of FGD1 24 0.67 6.82 2.83
53 INT76375 Binding of Cit 6 0.12 0.39 2.77
54 INT27207 Gene_expression of Psd 31 0.73 15.44 2.75
55 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
56 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
57 INT182893 Gene_expression of Sh2b2 8 0.65 1.74 2.65
58 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
59 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63
60 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
61 INT23775 Regulation of S100B 24 0.62 16.75 2.57
62 INT98871 Regulation of Psd 8 0.42 4.55 2.57
63 INT152865 Positive_regulation of Localization of S100b 3 0.68 0 2.53
64 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45
65 INT195085 Gene_expression of S100b 12 0.56 12.26 2.33
66 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
67 INT168115 Transcription of Tln2 1 0.02 0 2.06
68 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
69 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
70 INT134916 Localization of Aif1 3 0.73 1.58 2
71 INT110003 Phosphorylation of Plcg1 2 0.37 0.91 1.96
72 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96
73 INT189239 Binding of GSN 11 0.36 9.34 1.93
74 INT99416 Negative_regulation of Bcar1 1 0.34 0.64 1.84
75 INT26369 Gene_expression of S100A6 19 0.65 5.39 1.81
76 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77
77 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
78 INT134915 Binding of Aif1 4 0.36 1.72 1.72
79 INT189226 Protein_catabolism of GSN 3 0.54 7.1 1.7
80 INT53532 Gene_expression of Lcp1 10 0.70 11.57 1.69
81 INT23881 Gene_expression of Bcar1 8 0.52 2.48 1.69
82 INT234827 Positive_regulation of RAB5A 3 0.59 0.54 1.69
83 INT152864 Regulation of Localization of S100b 2 0.52 0 1.66
84 INT263398 Positive_regulation of Abl1 1 0.60 1.44 1.66
85 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
86 INT323984 Regulation of Trpm7 2 0.61 0.66 1.64
87 INT76376 Negative_regulation of Binding of Cit 1 0.15 0.22 1.64
88 INT199222 Gene_expression of SAMSN1 14 0.57 18.97 1.61
89 INT325940 Positive_regulation of Gene_expression of Ezr 42 0.69 27.79 1.56
90 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
91 INT125767 Positive_regulation of Gene_expression of S100b 6 0.49 4.08 1.52
92 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
93 INT196105 Gene_expression of Trpm7 8 0.77 3.03 1.51
94 INT335495 Regulation of Regulation of Aif1 5 0.21 1.22 1.51
95 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
96 INT77311 Localization of Aif1 10 0.75 4.21 1.5
97 INT345015 Positive_regulation of Gene_expression of GSN 1 0.49 3.58 1.5
98 INT121347 Binding of GNAS 8 0.13 3.99 1.47
99 INT14916 Binding of RASA1 15 0.37 13.64 1.44
100 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
101 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42
102 INT162308 Phosphorylation of GNAS 3 0.01 1.71 1.4
103 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
104 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
105 INT112988 Positive_regulation of Transcription of S100b 2 0.47 1.62 1.36
106 INT115350 Positive_regulation of Localization of Baiap2 1 0.45 0.76 1.36
107 INT112987 Transcription of S100b 2 0.53 1.61 1.35
108 INT51064 Regulation of Gene_expression of S100B 13 0.60 5.02 1.34
109 INT3404 Binding of BCAR1 10 0.33 7.97 1.33
110 INT125766 Regulation of S100b 7 0.38 4.31 1.33
111 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32
112 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
113 INT254397 Negative_regulation of Gene_expression of GSN 2 0.41 3.56 1.28
114 INT72147 Phosphorylation of Cttn 3 0.28 0.64 1.27
115 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25
116 INT126812 Gene_expression of Cttn 9 0.57 0.81 1.23
117 INT101302 Positive_regulation of Gene_expression of Aif1 5 0.37 3.56 1.23
118 INT110001 Binding of Plcg1 2 0.36 0.44 1.21
119 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
120 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
121 INT345013 Regulation of GSN 4 0.51 3.49 1.11
122 INT272172 Regulation of Positive_regulation of Aif1 3 0.26 0 1.11
123 INT102758 Negative_regulation of Abl1 2 0.51 1.13 1.1
124 INT167182 Binding of Psd 9 0.41 13.08 1.06
125 INT161706 Negative_regulation of Gene_expression of S100B 8 0.43 2.69 1.06
126 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06
127 INT293678 Positive_regulation of Gene_expression of S100A6 1 0.34 2.42 1.04
128 INT211723 Binding of Rasa1 3 0.07 0.85 1.03
129 INT110000 Positive_regulation of Phosphorylation of Plcg1 1 0.23 0.49 1.02
130 INT316159 Regulation of FGD1 1 0.01 0.59 0.99
131 INT126672 Binding of Bcar1 7 0.20 2.67 0.98
132 INT78014 Negative_regulation of ITGA5 1 0.01 1.71 0.98
133 INT51066 Binding of S100B 24 0.48 13.5 0.97
134 INT77639 Phosphorylation of Plcg1 5 0.68 0.47 0.97
135 INT250699 Binding of CDK6 3 0.33 2.54 0.97
136 INT43919 Negative_regulation of S100A6 19 0.16 4.45 0.96
137 INT161766 Localization of Psd 7 0.75 3.53 0.96
138 INT71917 Gene_expression of ACTN1 4 0.24 2.27 0.96
139 INT191478 Negative_regulation of Positive_regulation of Aif1 2 0.25 0.31 0.95
140 INT162167 Negative_regulation of Gene_expression of ARF6 1 0.38 0 0.94
141 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
142 INT204136 Regulation of Gene_expression of BCAR1 2 0.21 0.62 0.93
143 INT144087 Positive_regulation of Trpm7 3 0.69 1.23 0.92
144 INT162168 Gene_expression of ARF6 1 0.68 0 0.92
145 INT269471 Positive_regulation of Binding of RAB5A 1 0.43 0 0.92
146 INT263387 Binding of Abl1 8 0.42 0.86 0.91
147 INT199226 Positive_regulation of SAMSN1 6 0.57 10.2 0.9
148 INT134918 Positive_regulation of Localization of Aif1 1 0.49 0.32 0.88
149 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87
150 INT34188 Positive_regulation of Localization of FGD1 1 0.01 0 0.87
151 INT34185 Negative_regulation of Localization of FGD1 1 0.00 0 0.87
152 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
153 INT269481 Positive_regulation of Localization of RAB5A 1 0.43 0 0.86
154 INT168118 Negative_regulation of Transcription of Tln2 1 0.02 0 0.84
155 INT167424 Positive_regulation of Pak1 1 0.14 1.43 0.83
156 INT225221 Negative_regulation of Nf2 1 0.57 18.06 0.83
157 INT208060 Positive_regulation of Eps8l1 1 0.05 0.86 0.8
158 INT355888 Negative_regulation of Trpm7 1 0.58 0.87 0.8
159 INT254401 Positive_regulation of GSN 4 0.38 2 0.79
160 INT180300 Positive_regulation of Positive_regulation of S100B 3 0.50 2.07 0.79
161 INT128447 Positive_regulation of Localization of S100B 2 0.67 0.9 0.79
162 INT257400 Positive_regulation of Gene_expression of FGD1 3 0.50 0.79 0.78
163 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
164 INT237991 Positive_regulation of Aif1 4 0.04 4.87 0.77
165 INT142083 Positive_regulation of AIF1 4 0.12 4.86 0.77
166 INT73433 Gene_expression of S100a6 10 0.71 2.74 0.76
167 INT287270 Binding of Ezr 8 0.36 1.78 0.76
168 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76
169 INT72149 Regulation of Cttn 3 0.31 0.95 0.76
170 INT139945 Transcription of Aif1 2 0.65 0.89 0.76
171 INT215783 Localization of Gnas 1 0.12 1.64 0.76
172 INT269483 Regulation of Gene_expression of RAB5A 1 0.38 0.14 0.76
173 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75
174 INT241499 Binding of Abl1 23 0.47 8.86 0.75
175 INT114035 Negative_regulation of Gene_expression of Psd 3 0.26 1.06 0.75
176 INT152863 Negative_regulation of Localization of S100b 1 0.42 0 0.75
177 INT147008 Negative_regulation of Gene_expression of S100b 2 0.27 0.55 0.74
178 INT67252 Regulation of Pdpn 1 0.00 0.9 0.74
179 INT195107 Localization of S100b 3 0.51 2.63 0.73
180 INT284739 Positive_regulation of Gene_expression of Sh2b2 2 0.26 0.83 0.71
181 INT321007 Protein_catabolism of Cttn 1 0.03 0.05 0.71
182 INT158084 Negative_regulation of FGD1 4 0.21 1.82 0.69
183 INT309322 Gene_expression of AIF1 7 0.14 2.64 0.68
184 INT182036 Gene_expression of Sh2b2 2 0.13 1.74 0.67
185 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66
186 INT279647 Regulation of Cit 1 0.27 0 0.64
187 INT202848 Gene_expression of Nf2 5 0.59 4.93 0.63
188 INT254402 Localization of GSN 2 0.78 2.73 0.63
189 INT44092 Binding of ACTN1 7 0.20 1.52 0.62
190 INT3501 Localization of Sh2b2 6 0.73 0.88 0.62
191 INT115347 Regulation of Localization of Baiap2 1 0.23 0.38 0.62
192 INT195095 Positive_regulation of Gene_expression of S100b 4 0.36 5.37 0.61
193 INT318499 Regulation of AIF1 2 0.03 4.89 0.6
194 INT249551 Negative_regulation of Transcription of GNAS 1 0.06 0.16 0.6
195 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
196 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
197 INT130971 Binding of Slc9a3r1 2 0.39 0.32 0.59
198 INT110002 Regulation of Positive_regulation of Plcg1 1 0.11 0.4 0.59
199 INT172054 Binding of PDLIM7 1 0.17 1.29 0.59
200 INT199225 Localization of SAMSN1 1 0.62 6.07 0.57
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