GO:0001755

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Name neural crest cell migration
Categary Process
Go Slim No
Go Link GO:0001755
Unique Molecular Interactions 514
Total Molecular Interactions 692
Total Single Events 3986
Pain Genes Associated 49

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neural crest cell migration. They are ordered first by their pain relevance and then by number of times they were reported for neural crest cell migration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
2 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
3 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
4 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
5 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
6 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
7 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
8 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
9 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
10 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
11 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
12 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
13 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
14 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
15 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
16 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
17 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
18 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
19 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
20 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
21 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
22 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
23 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
24 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
25 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
26 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
27 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
28 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
29 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
30 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
31 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
32 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
33 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
34 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
35 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
36 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
37 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
38 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
39 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
40 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
41 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
42 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
43 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
44 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
45 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
46 INT53844 Penk Regulation of Kitl 1 0.00 0.9 1
47 INT53845 Positive_regulation of Penk Regulation of Kitl 1 0.00 0.9 1
48 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
49 INT180770 Gdnf Positive_regulation of Zbtb38 1 0.00 0.27 0.99
50 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
51 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
52 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
53 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
54 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
55 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
56 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
57 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
58 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
59 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92
60 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
61 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
62 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
63 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
64 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
65 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
66 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
67 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
68 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
69 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
70 INT108128 GDNF Regulation of Localization of GRHL3 1 0.24 0.18 0.83
71 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
72 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
73 INT189018 Nka1 Regulation of Pax3 1 0.01 0.1 0.81
74 INT103331 Ngf Positive_regulation of Gdnf 1 0.01 0.57 0.8
75 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
76 INT103334 Gdnf Regulation of Gene_expression of TRPV1 1 0.02 0.53 0.77
77 INT103333 Gdnf Regulation of TRPV1 1 0.02 0.53 0.77
78 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
79 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76
80 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
81 INT344383 Olfr360 Regulation of Gene_expression of Efnb1 1 0.01 1.27 0.74
82 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
83 INT180783 Binding of Gdnf and Man2a2 1 0.00 0.52 0.71
84 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
85 INT180775 Binding of Gdnf and Gfra1 1 0.06 0.52 0.71
86 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
87 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
88 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
89 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
90 INT213971 Mthfd1 Positive_regulation of Gene_expression of Pax3 1 0.00 0.14 0.68
91 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
92 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67
93 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
94 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65
95 INT114845 RET Regulation of Gene_expression of Lgals1 1 0.02 0.84 0.65
96 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
97 INT122777 Gdnf Negative_regulation of Gene_expression of Trpv1 1 0.36 0.8 0.62
98 INT74395 Htr2b Negative_regulation of Pdyn 1 0.03 0 0.61
99 INT122774 Gdnf Negative_regulation of Positive_regulation of Trpv1 1 0.32 0.78 0.61
100 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
101 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
102 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
103 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58
104 INT1211 Binding of Kitl and Cpz 1 0.27 0 0.58
105 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58
106 INT91267 Gdnf Negative_regulation of Gdnf 1 0.05 0.81 0.58
107 INT98034 Binding of Ret and Trpv1 1 0.43 0.42 0.58
108 INT1210 Negative_regulation of Binding of Kitl and Cpz 1 0.33 0 0.58
109 INT145431 Pax3 Positive_regulation of Positive_regulation of Ros1 1 0.02 0.07 0.57
110 INT260821 NRP2 Positive_regulation of Gene_expression of TNF 1 0.01 1.48 0.56
111 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54
112 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
113 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52
114 INT194916 Kitl Positive_regulation of Gene_expression of Mmp1a 1 0.00 0.85 0.52
115 INT130157 Pomc Regulation of Gene_expression of Ednrb 1 0.14 0 0.52
116 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
117 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51
118 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
119 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
120 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51
121 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
122 INT97950 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of ST3GAL3 1 0.02 0.72 0.5
123 INT98117 Gdnf Regulation of SCN11A 1 0.05 0.39 0.5
124 INT242597 Gene_expression of Gdnf Negative_regulation of Trpv1 1 0.27 0.08 0.5
125 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5
126 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
127 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49
128 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
129 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49
130 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
131 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
132 INT242604 Gdnf Regulation of Gene_expression of Trpv1 1 0.17 0.36 0.48
133 INT94018 Binding of EDN2 and EDN3 1 0.19 0 0.48
134 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
135 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
136 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
137 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
138 INT151456 Binding of KITLG and Insrr 1 0.00 0.21 0.46
139 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
140 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
141 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45
142 INT98118 Gdnf Regulation of SCN11A 1 0.01 0.34 0.45
143 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45
144 INT104459 Gdnf Regulation of Ngf 1 0.26 0.56 0.45
145 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
146 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
147 INT126339 Pax3 Regulation of Insrr 1 0.00 0.56 0.44
148 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
149 INT127074 Gdnf Regulation of Gene_expression of Jun 1 0.10 0.28 0.43
150 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
151 INT127072 Gdnf Regulation of Gene_expression of Fos 1 0.38 0.28 0.43
152 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
153 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
154 INT294910 Pax3 Regulation of Positive_regulation of Il1 1 0.02 2.03 0.42
155 INT338059 Nrtn Positive_regulation of Gene_expression of F2r 1 0.12 0.45 0.41
156 INT148436 Binding of Gdnf and Ngf 1 0.35 1.14 0.4
157 INT36340 Binding of NRP2 and Penk 1 0.04 0.07 0.39
158 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
159 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
160 INT78627 Gdnf Negative_regulation of Negative_regulation of P2rx3 1 0.00 0.42 0.38
161 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
162 INT2428 Pag1 Regulation of Kitl 1 0.00 0.41 0.38
163 INT15104 Binding of Pax3 and Penk 1 0.01 0 0.37
164 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37
165 INT140869 Binding of Gdnf and Trib3 1 0.04 0.15 0.37
166 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
167 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
168 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
169 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
170 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
171 INT137437 Nrtn Regulation of Sema3a 1 0.36 0.82 0.35
172 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
173 INT137442 Nrtn Regulation of Sema3a 1 0.04 0.81 0.34
174 INT137440 Nrtn Negative_regulation of Sema3a 1 0.34 0.77 0.34
175 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
176 INT304339 Negative_regulation of CD79A Positive_regulation of NRP2 1 0.06 0.86 0.33
177 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32
178 INT304338 CD79A Positive_regulation of NRP2 1 0.08 0.84 0.32
179 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31
180 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
181 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
182 INT97549 KITLG Negative_regulation of Mc1r 1 0.01 0.15 0.3
183 INT356282 Gdnf Positive_regulation of Trib3 1 0.00 0.17 0.3
184 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
185 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
186 INT260841 Il6 Positive_regulation of Localization of NRP2 1 0.00 0.7 0.29
187 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
188 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
189 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
190 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
191 INT347531 Binding of Nrp2 and Sema3b 1 0.04 0.99 0.28
192 INT180788 Gdnf Regulation of Trpv1 1 0.13 0.2 0.28
193 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
194 INT54639 Edn3 Negative_regulation of Edn2 1 0.00 0 0.28
195 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27
196 INT294905 Binding of Hgf and Pax3 1 0.01 1.54 0.25
197 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25
198 INT335028 Fgf15 Positive_regulation of Fgfr4 1 0.40 0.31 0.25
199 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
200 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24

Single Events

The table below shows the top 100 pain related interactions that have been reported for neural crest cell migration. They are ordered first by their pain relevance and then by number of times they were reported in neural crest cell migration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8534 Localization of Pax3 85 0.59 28.71 82.82
2 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
3 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
4 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85
5 INT4913 Binding of Pax3 52 0.28 9.57 42.67
6 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
7 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
8 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
9 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
10 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
11 INT256285 Gene_expression of Efnb1 32 0.70 36.25 24.73
12 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
13 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
14 INT344368 Positive_regulation of Gene_expression of Efnb1 13 0.63 18.39 13.31
15 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
16 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
17 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
18 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
19 INT150285 Positive_regulation of Efnb1 6 0.29 10.22 11.44
20 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77
21 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
22 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43
23 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
24 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
25 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62
26 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29
27 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
28 INT77795 Localization of Gdnf 26 0.81 6.29 8.55
29 INT77794 Binding of Gdnf 15 0.48 8.38 8.22
30 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84
31 INT87546 Transcription of Gdnf 15 0.71 7.49 7.76
32 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47
33 INT83531 Gene_expression of KITLG 54 0.65 26 7.07
34 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
35 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65
36 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37
37 INT4911 Negative_regulation of Binding of Pax3 7 0.22 1.89 6.17
38 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
39 INT13352 Regulation of Kitl 11 0.45 3.91 6.07
40 INT87548 Negative_regulation of Gene_expression of Gdnf 9 0.54 5.67 5.94
41 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75
42 INT145188 Gene_expression of Efnb1 4 0.32 6.07 5.74
43 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73
44 INT7524 Localization of Kitl 9 0.74 3.45 5.49
45 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
46 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
47 INT25832 Negative_regulation of Kitl 9 0.43 3.59 5.07
48 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
49 INT78626 Regulation of Gdnf 7 0.45 3.3 4.64
50 INT29519 Gene_expression of Ednrb 8 0.66 1.99 4.55
51 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44
52 INT1209 Binding of Kitl 14 0.37 6.72 4.3
53 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
54 INT75688 Binding of KITLG 24 0.30 11.73 4.06
55 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04
56 INT28983 Regulation of Htr2b 3 0.22 0.26 3.96
57 INT5782 Gene_expression of Edn3 17 0.67 3.38 3.65
58 INT76815 Regulation of Gene_expression of Pax3 4 0.12 3.81 3.65
59 INT133590 Gene_expression of Nrtn 17 0.55 6.1 3.64
60 INT88008 Positive_regulation of Gene_expression of GDNF 14 0.70 8.9 3.61
61 INT242569 Positive_regulation of Ret 17 0.55 3.61 3.54
62 INT78625 Regulation of Gene_expression of Gdnf 7 0.37 2.5 3.47
63 INT88255 Regulation of Positive_regulation of Kitl 2 0.00 1.72 3.47
64 INT170438 Negative_regulation of Gene_expression of Pax3 4 0.04 1.03 3.42
65 INT344366 Negative_regulation of Gene_expression of Efnb1 1 0.53 5.02 3.29
66 INT84222 Regulation of Ednrb 4 0.45 2.24 3.25
67 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
68 INT55033 Localization of Edn3 7 0.80 1.4 3.05
69 INT99574 Positive_regulation of KITLG 10 0.39 6.74 2.96
70 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
71 INT209744 Transcription of Gdnf 5 0.67 1.36 2.84
72 INT344371 Phosphorylation of Efnb1 1 0.57 3.35 2.81
73 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
74 INT48807 Regulation of Binding of Pax3 2 0.13 0 2.59
75 INT128774 Regulation of Gene_expression of Ednrb 3 0.46 1 2.56
76 INT150288 Positive_regulation of Gene_expression of Efnb1 2 0.21 2.73 2.53
77 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52
78 INT63333 Gene_expression of RET 24 0.76 30.09 2.41
79 INT144366 Negative_regulation of Positive_regulation of Gdnf 4 0.41 1.43 2.41
80 INT36338 Gene_expression of NRP2 29 0.67 6.47 2.4
81 INT121224 Positive_regulation of Positive_regulation of Pax3 5 0.14 2.32 2.4
82 INT126473 Regulation of KITLG 5 0.14 7.86 2.34
83 INT242548 Regulation of Gene_expression of Ret 7 0.49 1.2 2.33
84 INT70558 Regulation of Localization of Pax3 1 0.20 0.07 2.29
85 INT98650 Positive_regulation of Localization of Gdnf 4 0.68 0.94 2.27
86 INT344367 Regulation of Gene_expression of Efnb1 1 0.41 4.64 2.24
87 INT50392 Regulation of Ret 6 0.54 3.51 2.22
88 INT242551 Negative_regulation of Gene_expression of Ret 5 0.41 1.01 2.21
89 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
90 INT78177 Negative_regulation of Gene_expression of Ednrb 4 0.41 1.04 2.16
91 INT88006 Positive_regulation of GDNF 5 0.45 2.55 2.14
92 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
93 INT102896 Binding of Ret 8 0.35 1.55 2.03
94 INT180801 Regulation of Binding of Gdnf 1 0.20 1.31 2.03
95 INT334975 Gene_expression of Fgf15 1 0.74 7.12 2.02
96 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
97 INT209745 Positive_regulation of Transcription of Gdnf 4 0.58 0.97 1.91
98 INT150284 Negative_regulation of Positive_regulation of Efnb1 1 0.18 1.53 1.86
99 INT178130 Binding of EDNRB 12 0.36 6.18 1.84
100 INT280889 Gene_expression of Sox10 19 0.72 3.45 1.78
101 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
102 INT196158 Binding of NRP2 16 0.06 7.03 1.73
103 INT201475 Negative_regulation of Positive_regulation of Ednrb 6 0.42 3.74 1.66
104 INT93182 Binding of Gdnf 7 0.35 1.96 1.64
105 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
106 INT98651 Regulation of Positive_regulation of Gdnf 3 0.44 0.97 1.58
107 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
108 INT161217 Positive_regulation of Htr2b 1 0.67 2.55 1.58
109 INT21951 Negative_regulation of Gene_expression of GDNF 5 0.43 2.82 1.57
110 INT242572 Positive_regulation of Gene_expression of Ret 6 0.40 0.29 1.56
111 INT146511 Gene_expression of Nrp2 25 0.78 8.67 1.55
112 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
113 INT213959 Transcription of Pax3 2 0.03 0.68 1.54
114 INT139514 Localization of EDNRB 7 0.73 4.63 1.52
115 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
116 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
117 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
118 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
119 INT114298 Positive_regulation of Gene_expression of Ednrb 4 0.36 0.79 1.42
120 INT237409 Localization of Erbb4 3 0.57 1.31 1.41
121 INT316075 Negative_regulation of Negative_regulation of Kitl 1 0.06 0.42 1.41
122 INT87547 Negative_regulation of Transcription of Gdnf 1 0.58 1.24 1.4
123 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39
124 INT108130 Localization of GDNF 3 0.74 1.36 1.38
125 INT98653 Negative_regulation of Localization of Gdnf 1 0.57 0.31 1.35
126 INT228036 Negative_regulation of Cfl1 1 0.09 1.1 1.34
127 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
128 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
129 INT189015 Negative_regulation of Positive_regulation of Pax3 1 0.12 0.31 1.31
130 INT44746 Localization of Ret 3 0.48 1.23 1.28
131 INT170442 Positive_regulation of Binding of Pax3 2 0.17 2.05 1.24
132 INT223448 Localization of Ret 2 0.60 0.58 1.23
133 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
134 INT118779 Positive_regulation of Protein_catabolism of Pax3 1 0.47 0.05 1.2
135 INT200838 Positive_regulation of Isl1 6 0.60 0.73 1.19
136 INT161216 Positive_regulation of Gene_expression of Htr2b 1 0.49 1.87 1.16
137 INT161219 Gene_expression of Htr2b 4 0.75 2.01 1.14
138 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
139 INT172809 Gene_expression of ISL1 33 0.40 21.63 1.12
140 INT21670 Localization of Lama5 1 0.31 1.11 1.1
141 INT180795 Positive_regulation of Positive_regulation of Gdnf 2 0.29 0.1 1.07
142 INT109396 Negative_regulation of RET 12 0.42 14.92 1.06
143 INT134859 Gene_expression of Lama5 3 0.39 4.47 1.06
144 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
145 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
146 INT108985 Negative_regulation of Regulation of Gdnf 1 0.43 1.11 1.04
147 INT133842 Binding of SOX10 3 0.38 5.79 1.02
148 INT156991 Positive_regulation of EFNB1 1 0.01 0.91 1
149 INT86559 Negative_regulation of KITLG 8 0.41 3.54 0.99
150 INT208932 Regulation of Ret 6 0.49 1.49 0.97
151 INT78181 Negative_regulation of EDNRB 6 0.57 4.46 0.95
152 INT2425 Negative_regulation of Ret 3 0.58 1.77 0.94
153 INT30157 Gene_expression of Htr2b 2 0.48 0 0.94
154 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93
155 INT107609 Regulation of EFNB1 1 0.00 0 0.93
156 INT148861 Gene_expression of EFNB1 3 0.55 1.23 0.92
157 INT243533 Positive_regulation of SOX10 1 0.35 3.93 0.92
158 INT92002 Transcription of Ret 3 0.43 1.58 0.9
159 INT118783 Negative_regulation of Protein_catabolism of Pax3 1 0.35 0.09 0.89
160 INT83461 Binding of RET 8 0.47 9.7 0.87
161 INT15247 Negative_regulation of Negative_regulation of Pax3 1 0.16 0 0.86
162 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
163 INT6243 Regulation of Edn3 2 0.35 0.2 0.83
164 INT173472 Positive_regulation of Isl1 1 0.03 0.2 0.83
165 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
166 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
167 INT133841 Gene_expression of SOX10 18 0.67 9.96 0.8
168 INT196182 Localization of NRP2 9 0.46 3.61 0.8
169 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
170 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
171 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78
172 INT270447 Binding of Smo 2 0.07 2.61 0.78
173 INT63912 Regulation of Negative_regulation of Kitl 1 0.00 0.59 0.77
174 INT121947 Negative_regulation of Positive_regulation of Gdnf 1 0.20 0.07 0.76
175 INT61122 Regulation of Regulation of Edn3 1 0.35 0.2 0.75
176 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
177 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
178 INT79784 Positive_regulation of RET 15 0.57 17.43 0.71
179 INT114842 Localization of RET 3 0.71 5.98 0.71
180 INT249511 Binding of Efnb1 1 0.01 0.67 0.7
181 INT63556 Binding of Edn3 1 0.24 0.63 0.7
182 INT66940 Regulation of RET 7 0.52 5.61 0.69
183 INT236094 Localization of Gdnf 4 0.70 2.51 0.68
184 INT209746 Regulation of Positive_regulation of Gdnf 2 0.37 0.11 0.68
185 INT243779 Negative_regulation of Gene_expression of Isl1 2 0.30 2.62 0.68
186 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
187 INT335005 Regulation of Gene_expression of Fgf15 1 0.58 0.8 0.66
188 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
189 INT50061 Negative_regulation of Edn3 4 0.58 0.77 0.65
190 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
191 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
192 INT237411 Negative_regulation of Localization of Erbb4 1 0.25 0.08 0.64
193 INT57127 Binding of Htr2b 2 0.36 0.05 0.63
194 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
195 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
196 INT139513 Negative_regulation of Localization of EDNRB 2 0.41 0 0.62
197 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
198 INT241673 Phosphorylation of GDNF 2 0.79 1.06 0.61
199 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
200 INT139259 Gene_expression of Kitlg 4 0.62 1.32 0.6
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