GO:0001768

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Name establishment of T cell polarity
Categary Process
Go Slim No
Go Link GO:0001768
Unique Molecular Interactions 26
Total Molecular Interactions 28
Total Single Events 324
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for establishment of T cell polarity. They are ordered first by their pain relevance and then by number of times they were reported for establishment of T cell polarity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
2 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86
3 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38
4 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38
5 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
6 INT252292 CCL21 Regulation of Binding of Mthfd1 1 0.03 0.41 0.33
7 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
8 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
9 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18
10 INT181842 PHB2 Regulation of CCR7 1 0.00 0.7 0.14
11 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
12 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13
13 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13
14 INT265388 CCL21 Positive_regulation of Gene_expression of CXCL9 1 0.13 0.88 0.1
15 INT265389 CCL21 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.88 0.1
16 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
17 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
18 INT337174 Binding of TLR3 and Positive_regulation of CCR7 1 0.15 0.31 0.03
19 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 0.17 0.74 0.03
20 INT352082 Binding of CCR7 and ADAM11 1 0.15 0.76 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for establishment of T cell polarity. They are ordered first by their pain relevance and then by number of times they were reported in establishment of T cell polarity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
2 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
3 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48
4 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
5 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11
6 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
7 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
8 INT126514 Positive_regulation of CCR7 16 0.43 16.21 2.79
9 INT182224 Binding of CCL21 6 0.34 5.91 2.54
10 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45
11 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01
12 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
13 INT177509 Regulation of CCL21 6 0.45 5.43 1.66
14 INT221059 Negative_regulation of CCL21 5 0.28 2.48 1.58
15 INT145921 Localization of CCL21 4 0.73 2.41 1.58
16 INT33299 Binding of CCR7 3 0.31 2.88 1.45
17 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
18 INT181400 Negative_regulation of Ccl19 3 0.43 1.97 1.13
19 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
20 INT181367 Negative_regulation of Ccl21b 1 0.01 1.72 0.98
21 INT182239 Negative_regulation of Gene_expression of CCR7 1 0.36 1.16 0.91
22 INT184687 Transcription of Ccl19 1 0.68 1.04 0.9
23 INT181370 Positive_regulation of Ccl19 2 0.37 2.28 0.77
24 INT145922 Positive_regulation of Positive_regulation of CCL21 1 0.39 0.82 0.69
25 INT181366 Regulation of Ccl21b 1 0.01 0.52 0.69
26 INT116716 Positive_regulation of Gene_expression of CCR7 5 0.68 6.92 0.67
27 INT208591 Negative_regulation of Gene_expression of CCL21 2 0.40 0.92 0.6
28 INT252284 Binding of Ccl19 1 0.17 0.54 0.48
29 INT221052 Positive_regulation of Negative_regulation of CCL21 1 0.22 0.85 0.48
30 INT182236 Transcription of CCR7 2 0.58 1.07 0.47
31 INT354384 Regulation of CCL19 1 0.23 1.89 0.47
32 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43
33 INT177505 Regulation of CCR7 3 0.38 2.19 0.42
34 INT225008 Gene_expression of Ccl21 1 0.27 0.07 0.36
35 INT225010 Positive_regulation of Ccl21 1 0.20 0.12 0.33
36 INT208587 Transcription of CCL21 2 0.49 0.84 0.3
37 INT177508 Regulation of Gene_expression of CCL21 1 0.27 1.23 0.3
38 INT305840 Positive_regulation of Gene_expression of Ccr7 1 0.27 0.25 0.24
39 INT184699 Localization of Ccl19 1 0.72 0.47 0.24
40 INT265418 Negative_regulation of Negative_regulation of CCL21 1 0.20 0.32 0.22
41 INT227245 Localization of CCR7 4 0.47 0.74 0.18
42 INT220167 Localization of Ccr7 1 0.31 0.39 0.18
43 INT184666 Negative_regulation of Localization of Ccl19 1 0.41 0.25 0.15
44 INT285485 Negative_regulation of Gene_expression of Ccl19 1 0.07 1.15 0.1
45 INT285481 Positive_regulation of Gene_expression of Ccl19 1 0.08 1.15 0.1
46 INT265420 Negative_regulation of Transcription of CCL21 1 0.23 0.52 0.08
47 INT225009 Transcription of Ccl21 1 0.24 0 0.06
48 INT225005 Positive_regulation of Transcription of Ccl21 1 0.18 0 0.06
49 INT352112 Transcription of CCL19 1 0.38 1.37 0.06
50 INT352100 Positive_regulation of Transcription of CCL19 1 0.37 1.38 0.06
51 INT216078 Negative_regulation of CCR7 2 0.27 0.36 0.03
52 INT352095 Regulation of Gene_expression of CCL19 1 0.21 0.68 0.03
53 INT337244 Positive_regulation of Binding of CCR7 1 0.31 0.6 0.03
54 INT352097 Positive_regulation of Positive_regulation of CCR7 1 0.25 1.06 0
55 INT352113 Positive_regulation of Positive_regulation of CCL19 1 0.27 1.06 0
56 INT237846 Positive_regulation of Localization of CCL21 1 0.23 0.94 0
57 INT166967 Negative_regulation of Ccr7 1 0.09 0 0
58 INT352098 Negative_regulation of Gene_expression of CCL19 1 0.23 1.48 0
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