GO:0001771

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Name immunological synapse formation
Categary Process
Go Slim No
Go Link GO:0001771
Unique Molecular Interactions 21
Total Molecular Interactions 35
Total Single Events 301
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for immunological synapse formation. They are ordered first by their pain relevance and then by number of times they were reported for immunological synapse formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
2 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38
3 INT252292 CCL21 Regulation of Binding of Mthfd1 1 0.03 0.41 0.33
4 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
5 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
6 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18
7 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
8 INT181842 PHB2 Regulation of CCR7 1 0.00 0.7 0.14
9 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
10 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13
11 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13
12 INT265388 CCL21 Positive_regulation of Gene_expression of CXCL9 1 0.13 0.88 0.1
13 INT265389 CCL21 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.88 0.1
14 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
15 INT337174 Binding of TLR3 and Positive_regulation of CCR7 1 0.15 0.31 0.03
16 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 0.17 0.74 0.03
17 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
18 INT256988 Binding of Dlg1 and Rpe 1 0.06 0 0
19 INT263737 Binding of Dlg1 and Neto1 1 0.07 0 0
20 INT352082 Binding of CCR7 and ADAM11 1 0.15 0.76 0
21 INT256981 Binding of Dlg1 and Slc9a3r1 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for immunological synapse formation. They are ordered first by their pain relevance and then by number of times they were reported in immunological synapse formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
2 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
3 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48
4 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
5 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
6 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
7 INT126514 Positive_regulation of CCR7 16 0.43 16.21 2.79
8 INT182224 Binding of CCL21 6 0.34 5.91 2.54
9 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45
10 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
11 INT177509 Regulation of CCL21 6 0.45 5.43 1.66
12 INT221059 Negative_regulation of CCL21 5 0.28 2.48 1.58
13 INT145921 Localization of CCL21 4 0.73 2.41 1.58
14 INT33299 Binding of CCR7 3 0.31 2.88 1.45
15 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
16 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
17 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
18 INT182239 Negative_regulation of Gene_expression of CCR7 1 0.36 1.16 0.91
19 INT145922 Positive_regulation of Positive_regulation of CCL21 1 0.39 0.82 0.69
20 INT116716 Positive_regulation of Gene_expression of CCR7 5 0.68 6.92 0.67
21 INT208591 Negative_regulation of Gene_expression of CCL21 2 0.40 0.92 0.6
22 INT221052 Positive_regulation of Negative_regulation of CCL21 1 0.22 0.85 0.48
23 INT182236 Transcription of CCR7 2 0.58 1.07 0.47
24 INT354384 Regulation of CCL19 1 0.23 1.89 0.47
25 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43
26 INT177505 Regulation of CCR7 3 0.38 2.19 0.42
27 INT208587 Transcription of CCL21 2 0.49 0.84 0.3
28 INT177508 Regulation of Gene_expression of CCL21 1 0.27 1.23 0.3
29 INT319280 Positive_regulation of Dlg1 1 0.45 0.42 0.28
30 INT305840 Positive_regulation of Gene_expression of Ccr7 1 0.27 0.25 0.24
31 INT209224 Binding of Dlg1 3 0.13 0.22 0.23
32 INT265418 Negative_regulation of Negative_regulation of CCL21 1 0.20 0.32 0.22
33 INT227245 Localization of CCR7 4 0.47 0.74 0.18
34 INT220167 Localization of Ccr7 1 0.31 0.39 0.18
35 INT265420 Negative_regulation of Transcription of CCL21 1 0.23 0.52 0.08
36 INT256975 Binding of Dlg1 7 0.36 0 0.06
37 INT352112 Transcription of CCL19 1 0.38 1.37 0.06
38 INT352100 Positive_regulation of Transcription of CCL19 1 0.37 1.38 0.06
39 INT216078 Negative_regulation of CCR7 2 0.27 0.36 0.03
40 INT352095 Regulation of Gene_expression of CCL19 1 0.21 0.68 0.03
41 INT337244 Positive_regulation of Binding of CCR7 1 0.31 0.6 0.03
42 INT256961 Regulation of Gene_expression of Dlg1 1 0.33 0 0
43 INT352097 Positive_regulation of Positive_regulation of CCR7 1 0.25 1.06 0
44 INT256978 Positive_regulation of Dlg1 1 0.34 0 0
45 INT352113 Positive_regulation of Positive_regulation of CCL19 1 0.27 1.06 0
46 INT256952 Localization of Dlg1 1 0.55 0 0
47 INT237846 Positive_regulation of Localization of CCL21 1 0.23 0.94 0
48 INT256974 Gene_expression of Dlg1 1 0.50 0.08 0
49 INT166967 Negative_regulation of Ccr7 1 0.09 0 0
50 INT352098 Negative_regulation of Gene_expression of CCL19 1 0.23 1.48 0
51 INT263679 Transcription of Dlg1 1 0.12 0.07 0
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