GO:0001772

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Name immunological synapse
Categary Component
Go Slim No
Go Link GO:0001772
Unique Molecular Interactions 278
Total Molecular Interactions 472
Total Single Events 4104
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for immunological synapse. They are ordered first by their pain relevance and then by number of times they were reported for immunological synapse. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
2 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
3 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
4 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
5 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
6 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
7 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
8 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
9 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
10 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
11 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
12 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
13 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
14 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
15 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
16 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
17 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
18 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
19 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
20 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
21 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
22 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
23 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82
24 INT119772 Binding of Cd53 and Gfap 1 0.04 1.01 0.81
25 INT237204 Binding of LGALS4 and Cd3e 1 0.15 2.61 0.8
26 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78
27 INT81717 ITGAL Regulation of Gene_expression of ITGAM 1 0.30 0.17 0.78
28 INT81718 ITGAL Regulation of Gene_expression of FCGR3B 1 0.28 0.17 0.78
29 INT81711 ITGAL Regulation of Gene_expression of ITGB2 1 0.30 0.17 0.78
30 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
31 INT81713 ITGAL Regulation of ITGAM 1 0.30 0.17 0.77
32 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75
33 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
34 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
35 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66
36 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
37 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
38 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
39 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
40 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
41 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
42 INT265651 Binding of ITGAL and MYCN 1 0.00 0.46 0.62
43 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
44 INT73073 Binding of Cd3e and Oprk1 1 0.28 0.06 0.59
45 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
46 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
47 INT182348 Binding of Cd3e and Crp 1 0.15 2.33 0.56
48 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
49 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
50 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51
51 INT137137 Binding of HIVEP1 and ICAM1 1 0.01 0.68 0.51
52 INT92997 Positive_regulation of SFTPA1 Positive_regulation of Binding of ICAM1 1 0.15 0.26 0.51
53 INT56449 Aap Positive_regulation of Icam1 1 0.31 0.75 0.5
54 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
55 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
56 INT333151 asa Regulation of Gene_expression of Icam1 1 0.09 0.59 0.48
57 INT333156 Tlx2 Regulation of Gene_expression of Icam1 1 0.06 0.59 0.48
58 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
59 INT103929 Cps1 Negative_regulation of Gene_expression of Icam1 1 0.01 0.13 0.47
60 INT103931 Cps1 Negative_regulation of Icam1 1 0.01 0.07 0.46
61 INT102691 RETNLB Positive_regulation of ITGAL 1 0.01 0.45 0.45
62 INT321860 Timp1 Negative_regulation of Icam1 1 0.22 1.13 0.39
63 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37
64 INT210952 Il1 Positive_regulation of Gene_expression of Icam1 1 0.01 0.86 0.37
65 INT230499 Gene_expression of Il1rn Negative_regulation of Gene_expression of Icam1 1 0.01 0.85 0.36
66 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36
67 INT78893 TNF Regulation of Gene_expression of ICAM1 1 0.24 0.38 0.35
68 INT94473 Binding of Cd3e and Trav6-3 2 0.05 0 0.34
69 INT193492 Binding of Icam1 and Sele 1 0.06 1.05 0.34
70 INT94474 Binding of Cd3e and Il27ra 1 0.02 0 0.34
71 INT329954 Binding of PRKCQ and SNRNP70 1 0.07 0.65 0.33
72 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
73 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29
74 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28
75 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28
76 INT62550 Il1f5 Regulation of Gene_expression of Icam1 1 0.05 0.44 0.28
77 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27
78 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27
79 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26
80 INT324064 Olfr1328 Negative_regulation of Gene_expression of Icam1 1 0.02 0.58 0.26
81 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25
82 INT129220 IFNG Positive_regulation of ICAM1 1 0.09 0.1 0.25
83 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
84 INT62549 Il1b Regulation of Icam1 1 0.13 0.39 0.25
85 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
86 INT62548 Il1b Regulation of Gene_expression of Icam1 1 0.22 0.39 0.25
87 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
88 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25
89 INT129219 IFNG Positive_regulation of Gene_expression of ICAM1 1 0.13 0.1 0.25
90 INT284589 Binding of ICAM1 and Crp 1 0.00 1.08 0.22
91 INT343910 TLR4 Regulation of Gene_expression of Icam1 1 0.04 1.3 0.22
92 INT237201 Cd3e Positive_regulation of KIT 1 0.03 0 0.21
93 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
94 INT141490 Negative_regulation of TNF Positive_regulation of ICAM1 1 0.29 0.58 0.21
95 INT202809 Cd3e Positive_regulation of Positive_regulation of Cxcl5 1 0.00 0.5 0.21
96 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21
97 INT158199 Negative_regulation of Binding of ICAM1 and AHSA1 1 0.15 0.3 0.2
98 INT158220 Positive_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
99 INT158223 Binding of ICAM1 and TNFSF14 1 0.04 0.3 0.2
100 INT158218 Binding of ICAM1 and AHSA1 1 0.14 0.3 0.2
101 INT158227 Negative_regulation of Binding of ICAM1 and MAPK1 1 0.16 0.3 0.2
102 INT158236 Positive_regulation of Binding of ICAM1 and MAPK1 1 0.19 0.3 0.2
103 INT158226 Binding of ICAM1 and MAPK1 1 0.14 0.3 0.2
104 INT158213 Positive_regulation of Binding of ICAM1 and AHSA1 1 0.18 0.3 0.2
105 INT158229 Negative_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
106 INT125152 IL1B Regulation of Gene_expression of ICAM1 1 0.50 0.1 0.2
107 INT158215 TNFSF14 Positive_regulation of ICAM1 1 0.05 0.3 0.2
108 INT214590 TIMP1 Regulation of ICAM1 1 0.10 0.29 0.19
109 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
110 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
111 INT273723 Binding of Icam1 and Trav6-3 1 0.05 1.97 0.19
112 INT214592 OAP Regulation of Gene_expression of ICAM1 1 0.02 0.77 0.19
113 INT316072 Binding of Cd3e and Ncam1 1 0.01 0.4 0.18
114 INT316074 Binding of Cd19 and Cd3e 1 0.02 0.39 0.17
115 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
116 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
117 INT277791 Binding of Icam1 and Itgal 1 0.03 0.37 0.17
118 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
119 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16
120 INT171945 PECAM1 Positive_regulation of Gene_expression of ICAM1 1 0.06 1.66 0.16
121 INT171544 PECAM1 Positive_regulation of ICAM1 1 0.01 0.47 0.16
122 INT171944 ICAM1 Positive_regulation of Gene_expression of PECAM1 1 0.06 1.66 0.16
123 INT117191 Binding of CXCR4 and Coro1a 1 0.39 0.28 0.16
124 INT273715 Positive_regulation of Binding of Icam1 and Trav6-3 1 0.07 1.51 0.16
125 INT273714 Positive_regulation of Binding of Icam1 and Itgb2 1 0.17 1.46 0.15
126 INT273717 Binding of Icam1 and Itgb2 1 0.17 1.45 0.15
127 INT63981 Sele Regulation of Positive_regulation of Icam1 1 0.17 0.71 0.15
128 INT213010 Hdl1 Negative_regulation of Gene_expression of Icam1 1 0.15 1.01 0.15
129 INT63980 Icam1 Regulation of Positive_regulation of Sele 1 0.17 0.71 0.15
130 INT79229 Binding of Icam1 and Ltbr 1 0.09 0.37 0.14
131 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
132 INT275983 Binding of Lat and Lcp2 1 0.23 0.41 0.13
133 INT173406 Binding of ITGAL and Itgb2 1 0.02 0.41 0.13
134 INT211313 Binding of Cd3e and Cd8a 1 0.02 0.19 0.13
135 INT194814 Cd3e Positive_regulation of Gene_expression of Il4 1 0.05 0 0.12
136 INT342406 AAVS1 Positive_regulation of Icam1 1 0.26 0.19 0.11
137 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
138 INT269785 Crp Positive_regulation of ICAM1 1 0.00 1.68 0.11
139 INT297938 Binding of ICAM1 and PAOD1 1 0.06 0.86 0.11
140 INT243215 Myst2 Negative_regulation of Gene_expression of Icam1 1 0.01 0.68 0.1
141 INT120700 PRSS1 Positive_regulation of ICAM1 1 0.15 0.29 0.1
142 INT277089 VEGFA Positive_regulation of Icam1 1 0.02 1.74 0.09
143 INT232652 Binding of CD2 and ITGAL 1 0.03 0.28 0.09
144 INT355580 VEGFA Positive_regulation of ICAM1 1 0.09 1.39 0.09
145 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
146 INT279400 GANAB Regulation of ITGAL 1 0.01 0.75 0.09
147 INT267626 Il1 Positive_regulation of ICAM1 1 0.00 0.79 0.09
148 INT173371 GPER Regulation of ITGAL 1 0.01 0.23 0.08
149 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
150 INT323640 Vcam1 Positive_regulation of Gene_expression of Icam1 1 0.42 1.75 0.08
151 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
152 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07
153 INT231863 Binding of ARHGDIA and Akt1 1 0.02 0.23 0.07
154 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 0.06 0.2 0.07
155 INT284503 Binding of ICAM1 and ITGAM 1 0.05 0.2 0.07
156 INT351142 Binding of Cd3e and Ighg2b 1 0.03 0.6 0.07
157 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07
158 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
159 INT313506 Binding of ICAM1 and SNRNP70 1 0.02 1.08 0.06
160 INT293220 Cd3e Regulation of Gene_expression of CNR2 1 0.03 0.06 0.06
161 INT284504 ITGAL Positive_regulation of Gene_expression of ITGAM 1 0.03 0.2 0.06
162 INT293221 Cd3e Regulation of Gene_expression of CNR1 1 0.03 0.06 0.06
163 INT287695 Binding of Cd53 and Use1 1 0.00 0.12 0.06
164 INT237190 Cd3e Positive_regulation of LPT 1 0.00 0.15 0.06
165 INT252338 Binding of Cd28 and Lat 1 0.30 0 0.06
166 INT252335 Regulation of Binding of Cd28 and Lat 1 0.37 0 0.06
167 INT178574 IL2RA Positive_regulation of Gene_expression of Cd3e 1 0.04 0.16 0.05
168 INT256984 Binding of Cd81 and Cd19 1 0.18 0.36 0.05
169 INT256990 Binding of Cd81 and Cr2 1 0.18 0.36 0.05
170 INT348818 Coro1a Positive_regulation of Gene_expression of TFDP3 1 0.19 0.42 0.04
171 INT199108 Akt1 Negative_regulation of Gene_expression of Arhgdia 1 0.02 0.07 0.04
172 INT249170 Binding of AKT1 and ARHGDIA 1 0.00 0.15 0.04
173 INT231806 ARHGDIA Negative_regulation of ARHGEF1 1 0.02 0.11 0.04
174 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04
175 INT348816 Coro1a Positive_regulation of Positive_regulation of Cd4 1 0.16 0.42 0.04
176 INT231865 ARHGDIA Negative_regulation of Sergef 1 0.01 0.05 0.04
177 INT336404 Binding of Cd3e and ALPK1 1 0.01 0.55 0.03
178 INT260811 Binding of ITGA4 and ITGAL 1 0.02 0 0.03
179 INT313501 Binding of ALOX12 and ICAM1 1 0.10 0.54 0.03
180 INT285407 ELF3 Regulation of ICAM1 1 0.03 0.91 0.03
181 INT251006 ICAM1 Positive_regulation of SELL 1 0.02 0.56 0
182 INT342094 Binding of Lat and Ie 1 0.05 1.9 0
183 INT221621 Binding of Lat and Fer 1 0.02 0 0
184 INT334471 Arhgdia Negative_regulation of Cdc42ep3 1 0.00 0 0
185 INT342095 Regulation of Binding of Lat and Ie 1 0.07 2.03 0
186 INT170121 ITGAL Regulation of CD44 1 0.07 1.07 0
187 INT325942 Binding of Icam1 and Ezr 1 0.15 0.39 0
188 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
189 INT331089 Binding of Cd3e and Itga2 1 0.09 0.2 0
190 INT256982 Binding of Cd81 and Rpe 1 0.13 0 0
191 INT256988 Binding of Dlg1 and Rpe 1 0.06 0 0
192 INT285289 TNF Positive_regulation of Icam1 1 0.23 1.44 0
193 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
194 INT91832 CD81 Negative_regulation of Gene_expression of Hbegf 1 0.01 0.07 0
195 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0
196 INT263737 Binding of Dlg1 and Neto1 1 0.07 0 0
197 INT194698 Binding of ZAP70 and LAT 1 0.04 0 0
198 INT341485 Binding of CD8A and GZMB 1 0.01 0.7 0
199 INT170587 GOPC Regulation of Gene_expression of ICAM1 1 0.13 0 0
200 INT321642 Binding of Cd3e and Spn 1 0.00 1.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for immunological synapse. They are ordered first by their pain relevance and then by number of times they were reported in immunological synapse. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
2 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
3 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71
4 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
5 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
6 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
7 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
8 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
9 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9
10 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16
11 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97
12 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21
13 INT88114 Gene_expression of Cd53 20 0.77 10.99 12.38
14 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
15 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
16 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
17 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
18 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
19 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
20 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
21 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
22 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08
23 INT61417 Gene_expression of ITGAL 36 0.75 29.62 6.15
24 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
25 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
26 INT144946 Localization of Icam1 21 0.75 21.84 5.33
27 INT56445 Regulation of Icam1 14 0.39 15.4 5.32
28 INT49405 Gene_expression of Itgal 40 0.75 27.3 4.8
29 INT87322 Binding of ITGAL 23 0.47 15.73 4.68
30 INT170738 Binding of Icam1 23 0.37 25.49 4.09
31 INT62545 Regulation of Gene_expression of Icam1 17 0.49 14.26 4.06
32 INT119250 Positive_regulation of Cd53 8 0.37 3.46 3.81
33 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
34 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41
35 INT36286 Binding of Cd3e 33 0.36 10.11 3.21
36 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12
37 INT74216 Binding of Icam1 16 0.48 10.11 2.69
38 INT63846 Gene_expression of Prkcq 1 0.73 1.11 2.58
39 INT135470 Transcription of Icam1 10 0.63 12.04 2.41
40 INT61418 Positive_regulation of ITGAL 24 0.14 12.86 2.3
41 INT88113 Positive_regulation of Gene_expression of Cd53 6 0.50 1.32 2.3
42 INT172078 Localization of Cd3e 22 0.37 9.88 2.27
43 INT72865 Localization of Icam1 12 0.68 8.18 2.24
44 INT51658 Regulation of GZMA 1 0.00 1.48 2.03
45 INT90584 Gene_expression of GZMB 15 0.14 13.81 1.86
46 INT56446 Positive_regulation of Positive_regulation of Icam1 7 0.40 8.84 1.64
47 INT12942 Regulation of ITGAL 8 0.35 3.29 1.57
48 INT70993 Regulation of Positive_regulation of Icam1 2 0.45 1.22 1.57
49 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55
50 INT49404 Binding of Itgal 11 0.36 9.16 1.53
51 INT93005 Positive_regulation of Binding of ICAM1 5 0.68 4.55 1.42
52 INT83464 Positive_regulation of Localization of Icam1 3 0.46 3.71 1.4
53 INT62824 Negative_regulation of Positive_regulation of ICAM1 7 0.53 2.94 1.39
54 INT63339 Transcription of ICAM1 6 0.69 3.92 1.37
55 INT70954 Negative_regulation of Cd3e 11 0.41 4.22 1.31
56 INT63849 Regulation of Gene_expression of Prkcq 1 0.58 0.62 1.24
57 INT63847 Regulation of Prkcq 1 0.42 0.5 1.23
58 INT63856 Positive_regulation of Gene_expression of Prkcq 1 0.47 0.53 1.16
59 INT261599 Transcription of Icam1 6 0.50 4.55 1.07
60 INT51657 Negative_regulation of Regulation of GZMA 1 0.00 0.72 1.07
61 INT91830 Gene_expression of CD81 4 0.31 2.24 1.03
62 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
63 INT49406 Positive_regulation of Itgal 7 0.43 8.58 0.95
64 INT199009 Negative_regulation of Transcription of Icam1 4 0.38 3.81 0.95
65 INT81723 Regulation of Gene_expression of ITGAL 2 0.32 0.2 0.92
66 INT53710 Regulation of Negative_regulation of Arhgdia 1 0.18 0 0.92
67 INT57370 Gene_expression of Coro1a 4 0.58 1.36 0.91
68 INT53711 Negative_regulation of Arhgdia 1 0.28 0 0.91
69 INT89669 Negative_regulation of Positive_regulation of Prkcq 1 0.08 0.23 0.87
70 INT115964 Negative_regulation of ITGAL 7 0.34 3.76 0.86
71 INT89668 Positive_regulation of Prkcq 1 0.09 0.22 0.86
72 INT277329 Positive_regulation of Regulation of Cd53 1 0.03 0.4 0.83
73 INT119768 Positive_regulation of Binding of Cd53 1 0.05 1.01 0.8
74 INT119771 Binding of Cd53 1 0.04 1 0.8
75 INT277330 Regulation of Cd53 1 0.02 0.4 0.8
76 INT347211 Regulation of Localization of Icam1 1 0.54 7.36 0.79
77 INT174492 Positive_regulation of Gene_expression of Cd3e 8 0.39 5.08 0.77
78 INT186135 Negative_regulation of Binding of ITGAL 5 0.34 3.27 0.74
79 INT66607 Regulation of Positive_regulation of ICAM1 3 0.42 2.81 0.71
80 INT287685 Negative_regulation of Cd53 2 0.01 0.92 0.62
81 INT102695 Localization of ITGAL 2 0.73 1.26 0.61
82 INT297304 Regulation of Transcription of Icam1 2 0.21 2.08 0.6
83 INT87458 Binding of CD81 4 0.18 6.02 0.59
84 INT63357 Negative_regulation of Gene_expression of ITGAL 3 0.33 1.88 0.56
85 INT261598 Positive_regulation of Transcription of Icam1 3 0.24 2.56 0.55
86 INT74724 Regulation of Ptprj 2 0.05 0.35 0.51
87 INT157574 Positive_regulation of Localization of Icam1 1 0.46 0.56 0.51
88 INT91829 Positive_regulation of CD81 1 0.01 0.44 0.51
89 INT78813 Positive_regulation of Transcription of ICAM1 1 0.46 0.16 0.5
90 INT74725 Localization of Ptprj 1 0.14 0.15 0.5
91 INT133729 Positive_regulation of Gene_expression of ITGAL 8 0.49 2.96 0.48
92 INT172077 Positive_regulation of Localization of Cd3e 3 0.09 3.18 0.47
93 INT112949 Negative_regulation of Binding of Icam1 2 0.24 1.75 0.47
94 INT174159 Regulation of Binding of Icam1 1 0.03 1.31 0.47
95 INT155265 Regulation of Cd3e 7 0.17 2.62 0.46
96 INT63850 Negative_regulation of Prkcq 1 0.40 0 0.46
97 INT98072 Gene_expression of LAT 5 0.68 5.37 0.44
98 INT87456 Regulation of CD81 1 0.17 1.71 0.43
99 INT199011 Binding of Lat 11 0.32 6.03 0.42
100 INT87457 Negative_regulation of CD81 3 0.37 1.73 0.42
101 INT277788 Negative_regulation of Gene_expression of Itgal 4 0.29 2.05 0.39
102 INT158244 Phosphorylation of ICAM1 2 0.67 1.33 0.39
103 INT236453 Negative_regulation of Positive_regulation of Icam1 2 0.43 1.95 0.38
104 INT94933 Positive_regulation of Gene_expression of Bcl10 1 0.01 1.74 0.38
105 INT275954 Regulation of Lat 4 0.54 0.75 0.37
106 INT177231 Regulation of Regulation of ICAM1 1 0.06 0.66 0.37
107 INT30049 Gene_expression of Bcl10 4 0.51 2.36 0.35
108 INT214059 Binding of GZMB 2 0.02 1.36 0.35
109 INT267145 Negative_regulation of Binding of ICAM1 5 0.57 4.12 0.33
110 INT79260 Negative_regulation of Itgal 2 0.37 2.11 0.33
111 INT214613 Regulation of Binding of ICAM1 2 0.28 1.41 0.32
112 INT204566 Negative_regulation of Localization of Icam1 2 0.19 2.11 0.3
113 INT199087 Gene_expression of Arhgdia 2 0.10 0.07 0.29
114 INT114900 Negative_regulation of Positive_regulation of ITGAL 1 0.01 1.32 0.29
115 INT297295 Negative_regulation of Transcription of Icam1 1 0.27 1.57 0.29
116 INT319280 Positive_regulation of Dlg1 1 0.45 0.42 0.28
117 INT18505 Negative_regulation of Coro1a 4 0.57 0.9 0.26
118 INT205898 Negative_regulation of Gene_expression of Arhgdia 1 0.05 0 0.26
119 INT12940 Positive_regulation of Transcription of ITGAL 1 0.02 0.09 0.26
120 INT12941 Transcription of ITGAL 1 0.03 0.09 0.26
121 INT294738 Positive_regulation of Transcription of Icam1 2 0.44 1.74 0.24
122 INT136287 Regulation of Positive_regulation of Icam1 1 0.39 1.32 0.24
123 INT61416 Positive_regulation of Positive_regulation of ITGAL 4 0.11 0.85 0.23
124 INT79259 Regulation of Itgal 4 0.40 2.94 0.23
125 INT117808 Positive_regulation of Gene_expression of Itgal 3 0.10 2.12 0.23
126 INT209224 Binding of Dlg1 3 0.13 0.22 0.23
127 INT278687 Regulation of Positive_regulation of Cd3e 1 0.10 0.51 0.23
128 INT231829 Negative_regulation of ARHGDIA 2 0.09 1.01 0.21
129 INT256958 Positive_regulation of Cd81 1 0.66 0.67 0.18
130 INT146186 Negative_regulation of Negative_regulation of Icam1 1 0.11 0.86 0.17
131 INT270152 Positive_regulation of Lat 6 0.44 11.1 0.16
132 INT145856 Positive_regulation of GZMB 3 0.10 2.64 0.15
133 INT117316 Positive_regulation of GZMA 3 0.59 3.11 0.15
134 INT235724 Localization of Itgal 2 0.07 0.94 0.15
135 INT112950 Positive_regulation of Binding of Icam1 1 0.28 0.73 0.15
136 INT288159 Regulation of Gene_expression of Itgal 1 0.15 1.16 0.14
137 INT256967 Gene_expression of Cd81 1 0.74 0.75 0.13
138 INT270171 Positive_regulation of Positive_regulation of Lat 2 0.32 1.91 0.12
139 INT211285 Positive_regulation of Positive_regulation of Cd3e 1 0.25 0.35 0.11
140 INT214610 Regulation of Localization of ICAM1 1 0.28 0 0.11
141 INT256955 Binding of Cd81 1 0.46 1.19 0.11
142 INT211299 Regulation of Gene_expression of Cd3e 3 0.23 0.79 0.1
143 INT330980 Regulation of Negative_regulation of Icam1 1 0.21 0.68 0.09
144 INT70955 Negative_regulation of Negative_regulation of Cd3e 1 0.41 0.47 0.09
145 INT312847 Regulation of Localization of Cd3e 1 0.06 1.61 0.09
146 INT98071 Localization of LAT 1 0.62 0.63 0.09
147 INT231830 Negative_regulation of Phosphorylation of ARHGDIA 1 0.09 0 0.09
148 INT117809 Positive_regulation of Positive_regulation of Itgal 1 0.04 0.84 0.09
149 INT231831 Phosphorylation of ARHGDIA 2 0.17 0.15 0.08
150 INT180504 Phosphorylation of Cd3e 2 0.49 0.38 0.07
151 INT268730 Localization of Cd53 1 0.01 0.31 0.07
152 INT277786 Negative_regulation of Binding of Itgal 1 0.29 0.22 0.07
153 INT180505 Positive_regulation of Phosphorylation of Cd3e 1 0.06 0.38 0.07
154 INT256975 Binding of Dlg1 7 0.36 0 0.06
155 INT267150 Regulation of Transcription of ICAM1 2 0.26 0.86 0.06
156 INT275923 Gene_expression of Lat 6 0.59 13.31 0.05
157 INT149758 Binding of Coro1a 2 0.36 0.61 0.05
158 INT107191 Positive_regulation of Regulation of Icam1 1 0.44 0.87 0.05
159 INT267251 Gene_expression of Ptprj 1 0.12 2.02 0.05
160 INT83483 Regulation of Regulation of ITGAL 2 0.01 0.3 0.04
161 INT260808 Negative_regulation of Gene_expression of Cd3e 2 0.21 0.81 0.04
162 INT275933 Negative_regulation of Lat 1 0.51 0.07 0.04
163 INT277327 Transcription of Cd53 1 0.04 0 0.04
164 INT348794 Positive_regulation of Coro1a 1 0.17 0.64 0.04
165 INT194775 Positive_regulation of Positive_regulation of LAT 1 0.10 0 0.04
166 INT330788 Protein_catabolism of Cd3e 1 0.07 0 0.04
167 INT249236 Positive_regulation of Phosphorylation of ARHGDIA 1 0.05 0.15 0.04
168 INT199097 Positive_regulation of Gene_expression of Arhgdia 1 0.06 0.07 0.04
169 INT249284 Localization of ARHGDIA 1 0.07 0.15 0.04
170 INT349238 Negative_regulation of LAT 1 0.23 0.11 0.03
171 INT265385 Negative_regulation of Binding of Cd3e 1 0.04 0.23 0.03
172 INT194788 Positive_regulation of LAT 1 0.10 0 0.03
173 INT267249 Positive_regulation of Gene_expression of Ptprj 1 0.08 0.39 0.03
174 INT275949 Negative_regulation of Positive_regulation of Lat 2 0.37 2.34 0
175 INT221574 Transcription of Lat 2 0.44 1.3 0
176 INT211290 Regulation of Binding of Cd3e 2 0.23 0 0
177 INT256961 Regulation of Gene_expression of Dlg1 1 0.33 0 0
178 INT342086 Regulation of Positive_regulation of Lat 1 0.29 1.99 0
179 INT342092 Regulation of Transcription of Lat 1 0.29 0.6 0
180 INT83476 Positive_regulation of Regulation of ITGAL 1 0.00 0 0
181 INT186844 Gene_expression of GZMA 1 0.01 0.51 0
182 INT190021 Negative_regulation of Gene_expression of Bcl10 1 0.32 0.77 0
183 INT256978 Positive_regulation of Dlg1 1 0.34 0 0
184 INT256976 Negative_regulation of Cd81 1 0.18 0 0
185 INT342076 Localization of Lat 1 0.47 2.56 0
186 INT242531 Negative_regulation of Bcl10 1 0.02 1.09 0
187 INT256952 Localization of Dlg1 1 0.55 0 0
188 INT275930 Positive_regulation of Protein_catabolism of Lat 1 0.44 0.12 0
189 INT294502 Transcription of Cd3e 1 0.27 0 0
190 INT342083 Negative_regulation of Binding of Lat 1 0.27 0.78 0
191 INT79661 Phosphorylation of ITGAL 1 0.01 0 0
192 INT275948 Regulation of Protein_catabolism of Lat 1 0.39 0.12 0
193 INT256969 Negative_regulation of Localization of Cd81 1 0.41 0.1 0
194 INT342088 Negative_regulation of Localization of Lat 1 0.27 1.61 0
195 INT275934 Regulation of Binding of Lat 1 0.34 0 0
196 INT186845 Binding of GZMA 1 0.01 0.66 0
197 INT349232 Positive_regulation of Gene_expression of LAT 1 0.27 0.99 0
198 INT256953 Regulation of Cd81 1 0.26 0.22 0
199 INT256960 Positive_regulation of Gene_expression of Cd81 1 0.44 0 0
200 INT342080 Positive_regulation of Transcription of Lat 1 0.32 0.32 0
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