GO:0001812

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Name positive regulation of type I hypersensitivity
Categary Process
Go Slim No
Go Link GO:0001812
Unique Molecular Interactions 42
Total Molecular Interactions 48
Total Single Events 422
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of type I hypersensitivity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of type I hypersensitivity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
2 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
3 INT119030 Binding of POMC and Ighg1 1 0.06 0 0.52
4 INT203150 Binding of Ighg2b and IgG2a 1 0.11 1.35 0.47
5 INT68252 Penk Positive_regulation of Transcription of Ighg1 1 0.44 0 0.44
6 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39
7 INT112020 Binding of Ighg1 and IgG2a 2 0.25 0.36 0.36
8 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33
9 INT112019 Binding of Ifng and Ighg1 1 0.10 0.3 0.33
10 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
11 INT241138 Ighg1 Positive_regulation of Hand1 1 0.06 0.64 0.32
12 INT284047 Vtcn1 Negative_regulation of Gene_expression of Ighg2b 1 0.05 0.68 0.3
13 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
14 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
15 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
16 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16
17 INT107647 Ighg1 Negative_regulation of Arigg4 1 0.01 0.5 0.14
18 INT107645 Arigg4 Negative_regulation of Ighg1 1 0.01 0.5 0.14
19 INT351144 Binding of Ighg2b and Ighg2a 1 0.00 0.78 0.12
20 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
21 INT185073 Bpifa2 Positive_regulation of Ighg1 1 0.27 0.93 0.09
22 INT351142 Binding of Cd3e and Ighg2b 1 0.03 0.6 0.07
23 INT338429 Il9 Positive_regulation of Gene_expression of Fcer1a 1 0.05 0.31 0.07
24 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06
25 INT320353 IFNA1 Positive_regulation of Gene_expression of Ighg2b 1 0.02 0 0.05
26 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04
27 INT202546 Binding of FCER1A and IGHE 1 0.02 0.49 0.04
28 INT320351 Pnp Regulation of Ighg2b 1 0.02 0.31 0
29 INT215128 Ighm Regulation of Ighg1 1 0.12 0.27 0
30 INT215131 Ighg1 Regulation of Ighg2b 1 0.16 0.27 0
31 INT215127 Ighg1 Regulation of Ighm 1 0.12 0.27 0
32 INT84739 Binding of Ighg1 and Cea 1 0.31 0.43 0
33 INT320352 Pnp Positive_regulation of Ighg2b 1 0.03 0.08 0
34 INT284829 Binding of FCGR3A and Ighg1 1 0.00 0.13 0
35 INT289295 Binding of CD59 and Fcgr3 1 0.01 1.06 0
36 INT215129 Ighg1 Regulation of Gene_expression of Ctsd 1 0.35 0.26 0
37 INT194243 Binding of SFSWAP and Ighg1 1 0.01 0.46 0
38 INT215132 Ighm Regulation of Ighg2b 1 0.11 0.27 0
39 INT215130 Ighg1 Regulation of Negative_regulation of Ctsd 1 0.21 0.27 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of type I hypersensitivity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of type I hypersensitivity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92
2 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01
3 INT9223 Localization of Ighg1 22 0.78 11.03 3.67
4 INT49930 Binding of Ighg1 21 0.37 13.27 2.43
5 INT173504 Positive_regulation of Gene_expression of Ighg1 16 0.47 7.2 2.36
6 INT184006 Gene_expression of Ighg2b 21 0.71 7.97 1.86
7 INT68250 Regulation of Gene_expression of Ighg1 7 0.40 2.99 1.56
8 INT107641 Negative_regulation of Ighg1 19 0.39 11.44 1.54
9 INT112013 Negative_regulation of Gene_expression of Ighg1 7 0.38 3.57 1.42
10 INT68248 Transcription of Ighg1 3 0.61 3.02 1.25
11 INT139679 Positive_regulation of Ighg2b 11 0.55 10.57 1.1
12 INT180382 Gene_expression of Fcgr3 9 0.34 7.94 1.1
13 INT171113 Binding of Ighg2b 3 0.47 2.85 0.96
14 INT138683 Regulation of Ighg1 15 0.30 7.95 0.94
15 INT181711 Positive_regulation of Gene_expression of Fcgr3 2 0.08 1.67 0.74
16 INT184049 Positive_regulation of Gene_expression of Ighg2b 2 0.40 1.54 0.53
17 INT203131 Regulation of Binding of Ighg2b 1 0.31 1.36 0.49
18 INT68237 Positive_regulation of Transcription of Ighg1 1 0.44 0 0.43
19 INT39350 Positive_regulation of Ighg2a 2 0.35 2.39 0.37
20 INT220962 Positive_regulation of Localization of Ighg1 2 0.46 2.58 0.37
21 INT224714 Localization of Ighg2b 4 0.73 0.48 0.33
22 INT323835 Negative_regulation of Binding of Ighg1 1 0.23 0.67 0.31
23 INT323834 Regulation of Binding of Ighg1 1 0.24 0.69 0.31
24 INT215118 Negative_regulation of Ighg2b 2 0.30 0.93 0.28
25 INT238679 Negative_regulation of Localization of Ighg1 2 0.39 0.61 0.15
26 INT317803 Negative_regulation of Ighg2a 1 0.02 0.71 0.15
27 INT317802 Regulation of Ighg2a 1 0.01 0.49 0.14
28 INT317804 Regulation of Gene_expression of Ighg2a 1 0.01 0.5 0.14
29 INT317801 Gene_expression of Ighg2a 1 0.03 0.49 0.13
30 INT79184 Positive_regulation of Fcgr3 2 0.13 0.52 0.1
31 INT303410 Regulation of Ighg2b 2 0.25 1.22 0.09
32 INT303412 Positive_regulation of Regulation of Ighg2b 2 0.43 1.23 0.09
33 INT107642 Positive_regulation of Positive_regulation of Ighg1 2 0.30 1.35 0.08
34 INT133448 Gene_expression of Fcer1a 2 0.17 0.47 0.07
35 INT192405 Positive_regulation of Regulation of Ighg1 1 0.26 0 0.04
36 INT211289 Binding of Fcgr3 1 0.19 0.28 0.03
37 INT320337 Regulation of Gene_expression of Ighg2b 1 0.25 0 0.03
38 INT320331 Negative_regulation of Gene_expression of Ighg2b 1 0.39 0.05 0.03
39 INT211301 Negative_regulation of Binding of Fcgr3 1 0.22 0.34 0.03
40 INT277787 Protein_catabolism of Ighg1 1 0.35 0.11 0.03
41 INT133447 Positive_regulation of Fcer1a 1 0.01 0.19 0
42 INT133445 Negative_regulation of Gene_expression of Fcer1a 1 0.01 0.16 0
43 INT156795 Gene_expression of FCER1A 1 0.31 0 0
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