GO:0001837

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Name epithelial to mesenchymal transition
Categary Process
Go Slim No
Go Link GO:0001837
Unique Molecular Interactions 471
Total Molecular Interactions 594
Total Single Events 4371
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported for epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
3 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
4 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
5 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
6 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
7 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
8 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94
9 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
10 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
11 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
12 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
13 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
14 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
15 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
16 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
17 INT106312 NFKB1 Regulation of S100A4 1 0.14 1.1 0.83
18 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
19 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
20 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
21 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
22 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
23 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
24 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
25 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
26 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
27 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
28 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
29 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
30 INT182156 Binding of HGF and IL3RA 1 0.03 1.31 0.62
31 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
32 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
33 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
34 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
35 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
36 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
37 INT143861 Nfatc1 Regulation of Gene_expression of NUP214 1 0.00 0.61 0.52
38 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
39 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
40 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
41 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
42 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
43 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
44 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
45 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47
46 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
47 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
48 INT102556 HGF Positive_regulation of Phosphorylation of ELK1 1 0.10 0.46 0.47
49 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
50 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
51 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
52 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
53 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
54 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
55 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
56 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44
57 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
58 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43
59 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
60 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
61 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
62 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
63 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
64 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
65 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
66 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
67 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
68 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
69 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
70 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
71 INT294117 HGF Positive_regulation of PTGER2 1 0.02 0.36 0.31
72 INT243631 Binding of Hand1 and Nfatc1 1 0.04 0.76 0.3
73 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
74 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
75 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
76 INT74940 HGF Positive_regulation of CPOX 1 0.13 0.25 0.3
77 INT74942 HGF Positive_regulation of PTGS1 1 0.11 0.25 0.29
78 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29
79 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
80 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
81 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
82 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
83 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
84 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
85 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
86 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26
87 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
88 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
89 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
90 INT194810 Il4 Regulation of Positive_regulation of Nfatc1 1 0.02 0.15 0.25
91 INT254283 Il10 Negative_regulation of Nfatc1 1 0.02 0.31 0.25
92 INT128432 HTR1B Regulation of S100A4 1 0.49 0.28 0.24
93 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
94 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
95 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
96 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
97 INT80704 CAMP Positive_regulation of Gene_expression of HGF 1 0.50 0.46 0.22
98 INT80706 IL4I1 Positive_regulation of Gene_expression of HGF 1 0.06 0.43 0.22
99 INT80705 IL4I1 Positive_regulation of HGF 1 0.03 0.43 0.22
100 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
101 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
102 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
103 INT118434 HGF Positive_regulation of TRPV1 1 0.54 0.13 0.2
104 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
105 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
106 INT118435 HGF Positive_regulation of TRPV4 1 0.54 0.13 0.2
107 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
108 INT301290 Tnfsf11 Positive_regulation of Nfatc1 1 0.15 0.65 0.2
109 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
110 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
111 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
112 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
113 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
114 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
115 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
116 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
117 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
118 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
119 INT192902 HGF Regulation of Kdm5d 1 0.00 0.36 0.19
120 INT194830 MAPK1 Positive_regulation of Gene_expression of Nfatc1 1 0.02 0.08 0.19
121 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
122 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
123 INT57612 Binding of ALB and HGF 1 0.20 0.52 0.18
124 INT175596 Binding of ACAT1 and HGF 1 0.01 1.58 0.18
125 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
126 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
127 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
128 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
129 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
130 INT226503 BTPs Negative_regulation of Phosphorylation of Nfatc1 1 0.07 0.29 0.16
131 INT243632 Il12a Positive_regulation of Nfatc1 1 0.03 0.44 0.16
132 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
133 INT194838 Binding of CREB1 and Nfatc1 1 0.01 0.07 0.16
134 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
135 INT194816 MAPK1 Negative_regulation of Phosphorylation of Nfatc1 1 0.01 0.07 0.15
136 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
137 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
138 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
139 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
140 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
141 INT301278 Nfatc1 Regulation of Acp5 1 0.05 0.19 0.15
142 INT194836 MAPK1 Negative_regulation of Nfatc1 1 0.01 0.07 0.15
143 INT316479 Il6 Positive_regulation of Snai1 1 0.24 0.33 0.15
144 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
145 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
146 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
147 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
148 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
149 INT290444 S100A4 Regulation of TIMP1 1 0.00 1.3 0.14
150 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
151 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
152 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
153 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
154 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
155 INT301283 Nfatc1 Regulation of Ctsk 1 0.06 0.19 0.13
156 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
157 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
158 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
159 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
160 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
161 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
162 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
163 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
164 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12
165 INT243642 Binding of Nfatc1 and Twist1 1 0.08 0.23 0.12
166 INT69688 Tgfb1 Positive_regulation of Rel 1 0.50 0 0.12
167 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12
168 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
169 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
170 INT334863 Positive_regulation of Binding of Mpz and Nfatc1 1 0.08 0 0.11
171 INT301284 Tnfsf11 Positive_regulation of Localization of Nfatc1 1 0.16 0.32 0.11
172 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
173 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11
174 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
175 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
176 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
177 INT334866 Binding of Mpz and Nfatc1 1 0.06 0 0.11
178 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1
179 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
180 INT102245 TNF Positive_regulation of Binding of HIF1A 1 0.18 1.09 0.1
181 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
182 INT301288 Clec5a Regulation of Nfatc1 1 0.21 0.25 0.1
183 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
184 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
185 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
186 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
187 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1
188 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
189 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
190 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09
191 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
192 INT173062 Binding of HIF1A and VHLL 1 0.04 1.26 0.09
193 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
194 INT173057 Positive_regulation of HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.24 1.49 0.08
195 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
196 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
197 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
198 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
199 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08
200 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported in epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
2 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
3 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
4 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
5 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
6 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
7 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99
8 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
9 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
10 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
11 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
12 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
13 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
14 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68
15 INT86805 Localization of HGF 49 0.71 28.48 6.35
16 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
17 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
18 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
19 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
20 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
21 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
22 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
23 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
24 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
25 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
26 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
27 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
28 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
29 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
30 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
31 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
32 INT38033 Regulation of HGF 26 0.45 14.96 3.81
33 INT111532 Gene_expression of Nfatc1 15 0.75 5.27 3.73
34 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
35 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
36 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
37 INT74946 Negative_regulation of Gene_expression of HGF 14 0.58 6.29 3.39
38 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
39 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
40 INT106318 Gene_expression of S100A4 21 0.75 12.13 3.23
41 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
42 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
43 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
44 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
45 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
46 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
47 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
48 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
49 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
50 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
51 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
52 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
53 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
54 INT111528 Positive_regulation of Gene_expression of Nfatc1 5 0.67 3.24 2.52
55 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
56 INT194748 Positive_regulation of Nfatc1 16 0.64 5.07 2.44
57 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26
58 INT217447 Positive_regulation of Positive_regulation of Nfatc1 4 0.46 3.34 2.2
59 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
60 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
61 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
62 INT106317 Negative_regulation of Gene_expression of S100A4 6 0.41 2.86 2.11
63 INT62711 Binding of HGF 27 0.31 15.23 2.08
64 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
65 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
66 INT128453 Positive_regulation of S100A4 8 0.67 3.24 1.84
67 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
68 INT111534 Regulation of Nfatc1 11 0.29 2.11 1.77
69 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7
70 INT62712 Negative_regulation of HGF 19 0.58 7.21 1.67
71 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
72 INT112506 Transcription of HGF 14 0.64 16.71 1.64
73 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
74 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
75 INT55302 Binding of Snai1 2 0.31 1.94 1.63
76 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
77 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
78 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
79 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
80 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
81 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
82 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
83 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
84 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
85 INT992 Regulation of S100A4 21 0.60 1.47 1.46
86 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
87 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
88 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
89 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
90 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
91 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
92 INT86804 Protein_catabolism of HGF 3 0.14 1.53 1.3
93 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
94 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
95 INT110780 Localization of Notch1 2 0.06 0.47 1.19
96 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
97 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
98 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
99 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
100 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
101 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
102 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
103 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
104 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
105 INT74945 Regulation of Gene_expression of HGF 3 0.62 1.21 1.07
106 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
107 INT97032 Gene_expression of Snai1 3 0.52 0.58 1.04
108 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
109 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
110 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
111 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
112 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
113 INT6833 Binding of Notch1 4 0.36 0.05 0.94
114 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
115 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
116 INT114664 Binding of BMP2 12 0.37 6.54 0.91
117 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
118 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
119 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
120 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
121 INT190678 Binding of Nfatc1 6 0.26 1.04 0.83
122 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
123 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
124 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
125 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
126 INT106319 Negative_regulation of S100A4 2 0.41 0.89 0.82
127 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
128 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
129 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
130 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
131 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
132 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
133 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
134 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
135 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
136 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
137 INT180361 Positive_regulation of AMELX 7 0.12 6.03 0.76
138 INT190675 Phosphorylation of Nfatc1 6 0.56 0.68 0.76
139 INT141150 Localization of BMP7 4 0.56 2.84 0.76
140 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
141 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
142 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
143 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
144 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
145 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
146 INT242137 Negative_regulation of Positive_regulation of Gsk3b 7 0.39 2.99 0.67
147 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
148 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
149 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
150 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
151 INT106320 Positive_regulation of Gene_expression of S100A4 2 0.48 0.84 0.65
152 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
153 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
154 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
155 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
156 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
157 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
158 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
159 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
160 INT204006 Negative_regulation of Localization of Gsk3b 6 0.40 1.66 0.6
161 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
162 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
163 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
164 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
165 INT89126 Regulation of BMP7 7 0.45 2.5 0.58
166 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
167 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58
168 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
169 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
170 INT230679 Positive_regulation of Binding of Gsk3b 3 0.42 1.42 0.58
171 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
172 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
173 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
174 INT207380 Transcription of Nfatc1 6 0.67 1.32 0.54
175 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
176 INT102562 Positive_regulation of Positive_regulation of HGF 3 0.36 0.92 0.53
177 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
178 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
179 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
180 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
181 INT208537 Regulation of Gene_expression of Gsk3b 4 0.36 2.15 0.52
182 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
183 INT85808 Localization of BMP2 7 0.77 1.94 0.51
184 INT159214 Positive_regulation of Gene_expression of BMP7 6 0.46 2.16 0.51
185 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
186 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
187 INT61947 Positive_regulation of Regulation of HGF 2 0.46 1.35 0.48
188 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
189 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
190 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
191 INT207376 Positive_regulation of Transcription of Nfatc1 3 0.49 1.15 0.47
192 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
193 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
194 INT288540 Negative_regulation of Binding of Gsk3b 4 0.53 2.12 0.43
195 INT208552 Negative_regulation of Negative_regulation of Gsk3b 3 0.31 1.8 0.43
196 INT235064 Regulation of Positive_regulation of Gsk3b 3 0.41 1.5 0.42
197 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
198 INT180353 Binding of AMELX 10 0.04 15.34 0.4
199 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
200 INT204012 Regulation of Negative_regulation of Gsk3b 4 0.42 4.51 0.39
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