GO:0001845

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Name phagolysosome assembly
Categary Process
Go Slim No
Go Link GO:0001845
Unique Molecular Interactions 69
Total Molecular Interactions 78
Total Single Events 880
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phagolysosome assembly. They are ordered first by their pain relevance and then by number of times they were reported for phagolysosome assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
2 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
3 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
4 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
5 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
6 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
7 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
8 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
9 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
10 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
11 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
12 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
13 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
14 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
15 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
16 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
17 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
18 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
19 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
20 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
21 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
22 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
23 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
24 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
25 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
26 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
27 INT117191 Binding of CXCR4 and Coro1a 1 0.39 0.28 0.16
28 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
29 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
30 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
31 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
32 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
33 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
34 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
35 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
36 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
37 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
38 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
39 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
40 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
41 INT348818 Coro1a Positive_regulation of Gene_expression of TFDP3 1 0.19 0.42 0.04
42 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
43 INT348816 Coro1a Positive_regulation of Positive_regulation of Cd4 1 0.16 0.42 0.04
44 INT321772 Binding of Myo7a and Twf2 1 0.00 0 0
45 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
46 INT290104 Myo7a Regulation of RPE 1 0.03 0.75 0
47 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
48 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0
49 INT307460 P2rx7 Positive_regulation of Phosphorylation of Gsk3a 1 0.02 0 0
50 INT255019 Myo7a Positive_regulation of F10 1 0.00 0.06 0
51 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phagolysosome assembly. They are ordered first by their pain relevance and then by number of times they were reported in phagolysosome assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
2 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
3 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
4 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
5 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
6 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
7 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
8 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
9 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
10 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
11 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
12 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
13 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
14 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
15 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
16 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
17 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
18 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
19 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
20 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
21 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
22 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
23 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
24 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
25 INT57370 Gene_expression of Coro1a 4 0.58 1.36 0.91
26 INT92428 Regulation of Myo7a 2 0.44 1.23 0.91
27 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
28 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
29 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
30 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
31 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
32 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
33 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
34 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
35 INT129456 Positive_regulation of MYO7A 3 0.20 3.15 0.36
36 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
37 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
38 INT18505 Negative_regulation of Coro1a 4 0.57 0.9 0.26
39 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
40 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
41 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
42 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
43 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
44 INT124527 Positive_regulation of Myo7a 1 0.00 0.15 0.1
45 INT168521 Localization of Myo7a 1 0.18 0.17 0.1
46 INT307481 Phosphorylation of P2rx7 1 0.15 0.35 0.08
47 INT307480 Positive_regulation of Phosphorylation of P2rx7 1 0.09 0.35 0.08
48 INT129457 Regulation of Localization of MYO7A 1 0.19 0.33 0.08
49 INT129455 Localization of MYO7A 1 0.32 0.33 0.08
50 INT149758 Binding of Coro1a 2 0.36 0.61 0.05
51 INT348794 Positive_regulation of Coro1a 1 0.17 0.64 0.04
52 INT269884 Negative_regulation of Gene_expression of Coro1a 1 0.35 0.24 0
53 INT67802 Binding of MYO7A 1 0.05 0.07 0
54 INT264146 Gene_expression of MYO7A 1 0.05 1.36 0
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