GO:0001848

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Name complement binding
Categary Function
Go Slim No
Go Link GO:0001848
Unique Molecular Interactions 30
Total Molecular Interactions 35
Total Single Events 692
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for complement binding. They are ordered first by their pain relevance and then by number of times they were reported for complement binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
2 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7
3 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
4 INT187333 Binding of C4bpa and Car1 1 0.08 0 0.52
5 INT24222 Ifng Positive_regulation of Gene_expression of Serping1 1 0.00 0 0.26
6 INT238263 pma Positive_regulation of Gene_expression of Cd59 1 0.02 0.57 0.26
7 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19
8 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19
9 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18
10 INT131304 Binding of Serping1 and Sele 1 0.01 1.07 0.15
11 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14
12 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12
13 INT281042 Serping1 Regulation of MBL2 1 0.01 0.74 0.11
14 INT279511 Binding of Serping1 and C1ra 1 0.01 0.3 0.11
15 INT232011 SERPING1 Regulation of Negative_regulation of SERPINE1 1 0.01 0.45 0.07
16 INT251645 Binding of SERPING1 and CD79A 1 0.10 1.31 0.06
17 INT187332 C4bpa Regulation of Positive_regulation of Car1 1 0.13 0 0.04
18 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04
19 INT232013 SERPING1 Negative_regulation of C1S 1 0.24 0.72 0.04
20 INT232012 SERPING1 Negative_regulation of C1R 1 0.18 0.72 0.04
21 INT232016 SERPING1 Regulation of C1S 1 0.15 0.57 0
22 INT299709 S100A12 Regulation of CFB 1 0.00 0.05 0
23 INT299700 FGL1 Regulation of CFB 1 0.00 0.05 0
24 INT187336 Binding of C4bpa and Sec22b 1 0.01 0.06 0
25 INT299698 Binding of CFB and PSMC2 1 0.00 0.14 0
26 INT281041 Binding of MASP2 and Serping1 1 0.00 1.2 0
27 INT299707 ECB2 Regulation of CFB 1 0.00 0 0
28 INT310200 Binding of Serping1 and F12 1 0.21 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for complement binding. They are ordered first by their pain relevance and then by number of times they were reported in complement binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17
2 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92
3 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75
4 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75
5 INT83623 Gene_expression of Cd59 7 0.76 7.35 4.7
6 INT64843 Gene_expression of Serping1 19 0.67 8.88 2.72
7 INT156130 Binding of SERPING1 29 0.42 26.16 2.52
8 INT4585 Gene_expression of Serping1 19 0.46 12.4 2.35
9 INT83622 Positive_regulation of Gene_expression of Cd59 4 0.49 3.77 2.35
10 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14
11 INT186872 Gene_expression of C4bpa 6 0.24 1.33 2.07
12 INT40954 Regulation of Serping1 5 0.32 3.71 1.88
13 INT207035 Gene_expression of CFB 4 0.63 18.4 1.72
14 INT156672 Localization of SERPING1 10 0.74 12.15 1.25
15 INT144482 Negative_regulation of Gene_expression of SERPING1 8 0.43 6.06 0.89
16 INT83624 Positive_regulation of Cd59 2 0.49 1.41 0.82
17 INT74260 Positive_regulation of Serping1 5 0.64 6.05 0.8
18 INT146109 Positive_regulation of Serping1 4 0.59 2.73 0.68
19 INT186873 Positive_regulation of Gene_expression of C4bpa 4 0.18 0.39 0.62
20 INT146108 Regulation of Positive_regulation of Serping1 1 0.05 1.04 0.6
21 INT81371 Binding of Serping1 3 0.37 2.67 0.55
22 INT333326 Localization of C4bpa 1 0.06 0.08 0.42
23 INT94026 Regulation of SERPING1 12 0.61 10.28 0.37
24 INT186871 Regulation of C4bpa 4 0.16 1.08 0.37
25 INT187324 Binding of C4bpa 5 0.14 0.15 0.36
26 INT64842 Negative_regulation of Gene_expression of Serping1 2 0.35 0.56 0.36
27 INT316315 Negative_regulation of Binding of SERPING1 2 0.37 1.4 0.34
28 INT232021 Positive_regulation of Gene_expression of SERPING1 8 0.49 4.99 0.31
29 INT131301 Binding of Serping1 3 0.28 1.86 0.3
30 INT4586 Negative_regulation of Gene_expression of Serping1 3 0.30 2.12 0.28
31 INT187327 Positive_regulation of C4bpa 2 0.14 0.29 0.27
32 INT160768 Negative_regulation of Cd59 2 0.36 1.12 0.26
33 INT187328 Negative_regulation of C4bpa 2 0.12 0.07 0.26
34 INT142433 Regulation of Serping1 1 0.00 0 0.25
35 INT311965 Positive_regulation of Gene_expression of Serping1 2 0.16 1.33 0.24
36 INT228644 Positive_regulation of Negative_regulation of SERPING1 5 0.46 4.21 0.21
37 INT291074 Positive_regulation of Gene_expression of CFB 1 0.45 3.77 0.18
38 INT238251 Transcription of Cd59 1 0.30 0.19 0.18
39 INT232025 Regulation of Gene_expression of SERPING1 3 0.56 1.75 0.15
40 INT316318 Phosphorylation of SERPING1 2 0.81 1.7 0.13
41 INT238252 Negative_regulation of Gene_expression of Cd59 1 0.24 0.26 0.13
42 INT238254 Positive_regulation of Positive_regulation of Cd59 1 0.28 0.34 0.11
43 INT187325 Transcription of C4bpa 1 0.15 0.06 0.1
44 INT333322 Regulation of Gene_expression of C4bpa 1 0.03 0.24 0.09
45 INT37864 Regulation of Negative_regulation of Serping1 1 0.10 0.69 0.09
46 INT232027 Positive_regulation of Positive_regulation of SERPING1 2 0.46 1.48 0.08
47 INT160767 Regulation of Cd59 1 0.37 0.93 0.08
48 INT187331 Phosphorylation of C4bpa 1 0.23 0 0.07
49 INT333323 Positive_regulation of Localization of C4bpa 1 0.03 0 0.05
50 INT310196 Localization of Serping1 2 0.39 2.64 0.04
51 INT333320 Positive_regulation of Positive_regulation of C4bpa 1 0.03 0 0.04
52 INT207034 Binding of CFB 3 0.17 0.61 0.03
53 INT279452 Negative_regulation of Negative_regulation of Serping1 1 0.06 0.3 0.03
54 INT187330 Negative_regulation of Phosphorylation of C4bpa 1 0.12 0 0.03
55 INT229958 Negative_regulation of CFB 3 0.01 0.06 0
56 INT45413 Transcription of Serping1 1 0.68 0.9 0
57 INT326636 Positive_regulation of Gene_expression of Serping1 1 0.23 0.54 0
58 INT111831 Positive_regulation of Positive_regulation of Serping1 1 0.64 0 0
59 INT328285 Negative_regulation of Localization of SERPING1 1 0.37 0.95 0
60 INT204875 Negative_regulation of Positive_regulation of SERPING1 1 0.42 0.1 0
61 INT299680 Positive_regulation of CFB 1 0.01 0.13 0
62 INT281038 Positive_regulation of Negative_regulation of Serping1 1 0.10 2.63 0
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