GO:0001865

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Name NK T cell differentiation
Categary Process
Go Slim No
Go Link GO:0001865
Unique Molecular Interactions 83
Total Molecular Interactions 102
Total Single Events 432
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for NK T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for NK T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT192332 UBR7 Negative_regulation of TXK 1 0.00 1.38 0.63
2 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58
3 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31
4 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25
5 INT349653 Nfe2l2 Positive_regulation of Itk 1 0.00 0.79 0.22
6 INT285076 CCL16 Positive_regulation of Gene_expression of ITK 1 0.05 1.8 0.14
7 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09
8 INT309904 Binding of ERBB2 and TXK 1 0.01 0.23 0.08
9 INT110856 TXK Negative_regulation of Egf 1 0.02 1.2 0.08
10 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
11 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
12 INT309903 Binding of EGF and TXK 1 0.03 0.23 0.08
13 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07
14 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
15 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07
16 INT251776 Negative_regulation of TXK Negative_regulation of ERBB4 1 0.04 1.07 0.06
17 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
18 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06
19 INT251774 Negative_regulation of TXK Negative_regulation of EGFR 1 0.07 1.06 0.06
20 INT279281 TXK Regulation of CDCP1 1 0.00 1.61 0.05
21 INT251778 Negative_regulation of TXK Positive_regulation of KDR 1 0.03 0.99 0.05
22 INT251779 TXK Positive_regulation of KDR 1 0.03 0.99 0.05
23 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04
24 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04
25 INT292084 Binding of FLT3 and TXK 1 0.02 1.53 0.04
26 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04
27 INT292083 Binding of KDR and TXK 1 0.04 1.52 0.04
28 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04
29 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04
30 INT347300 Binding of ITK and CCL16 1 0.02 0.97 0.04
31 INT292085 Negative_regulation of Binding of FLT3 and TXK 1 0.02 1.54 0.04
32 INT292094 Binding of FLT4 and TXK 1 0.02 1.53 0.04
33 INT292095 Negative_regulation of Binding of KDR and TXK 1 0.04 1.53 0.04
34 INT292080 Binding of FLT1 and TXK 1 0.04 1.47 0.04
35 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04
36 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04
37 INT292086 Negative_regulation of Binding of FLT1 and TXK 1 0.04 1.48 0.04
38 INT347299 Binding of AKT1 and ITK 1 0.04 0.99 0.04
39 INT292093 Negative_regulation of Binding of FLT4 and TXK 1 0.03 1.53 0.04
40 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04
41 INT285068 ITK Regulation of CCL16 1 0.02 1.86 0.03
42 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03
43 INT208410 IGF1 Positive_regulation of TXK 1 0.08 0.9 0.03
44 INT285067 Negative_regulation of ITK Regulation of CCL16 1 0.04 1.1 0.03
45 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
46 INT351090 Phosphorylation of TXK Positive_regulation of EGFR 1 0.04 0.33 0
47 INT292680 Negative_regulation of TXK Negative_regulation of ABL1 1 0.00 0.26 0
48 INT223577 TXK Negative_regulation of EGFR 1 0.08 0.18 0
49 INT351602 TXK Positive_regulation of ERBB2 1 0.02 0.58 0
50 INT341631 EGFR Positive_regulation of TXK 1 0.05 0.42 0
51 INT279289 TXK Regulation of SRC 1 0.04 0.68 0
52 INT351604 TXK Positive_regulation of EGFR 1 0.02 1.78 0
53 INT324056 Binding of Itk and Furin 1 0.03 0.48 0
54 INT298437 Binding of ITK and SNAI1 1 0.05 1.16 0
55 INT326727 Sox10 Regulation of Regulation of Itk 1 0.02 0.06 0
56 INT347294 CCL16 Positive_regulation of Binding of ITK 1 0.02 0.78 0
57 INT294095 Binding of TXK and Gtf3a 1 0.00 2.33 0
58 INT285074 Positive_regulation of ITK Regulation of CCL16 1 0.04 0.77 0
59 INT268599 Mir10a Regulation of TXK 1 0.01 1.09 0
60 INT223583 TXK Negative_regulation of ERBB2 1 0.07 0.18 0
61 INT279283 TXK Regulation of PDGFRB 1 0.06 0.68 0
62 INT223581 TXK Negative_regulation of DBP 1 0.00 0.47 0
63 INT298449 Binding of ITK and Vim 1 0.01 0.58 0
64 INT303947 Binding of LEPR and TXK 1 0.00 0.63 0
65 INT298435 Binding of ITK and KNG1 1 0.01 0.58 0
66 INT285072 EGF Positive_regulation of ITK 1 0.03 0.77 0
67 INT236933 Ppara Positive_regulation of Itk 1 0.01 0.31 0
68 INT351085 Binding of EGFR and Positive_regulation of Phosphorylation of TXK 1 0.04 0.35 0
69 INT326726 Twist1 Regulation of Itk 1 0.02 0.84 0
70 INT294094 Binding of TXK and Eltd1 1 0.00 0.56 0
71 INT236935 Negative_regulation of Ppara Positive_regulation of Itk 1 0.01 0.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for NK T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in NK T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59
2 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09
3 INT118291 Binding of TXK 19 0.10 11.77 1.94
4 INT119520 Gene_expression of TXK 19 0.19 17.54 1.45
5 INT120075 Gene_expression of Itk 11 0.43 6.39 1.27
6 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1
7 INT119519 Positive_regulation of Gene_expression of TXK 3 0.09 2.92 1.02
8 INT109470 Negative_regulation of ITK 3 0.24 2.13 0.96
9 INT267894 Gene_expression of ITK 13 0.57 9.71 0.9
10 INT169706 Positive_regulation of Gene_expression of Itk 2 0.32 2.08 0.81
11 INT142184 Regulation of TXK 10 0.11 8.25 0.59
12 INT171683 Negative_regulation of Negative_regulation of TXK 3 0.06 1.28 0.46
13 INT269220 Positive_regulation of Gene_expression of ITK 4 0.14 3.07 0.41
14 INT269226 Positive_regulation of ITK 13 0.12 11.23 0.4
15 INT192343 Positive_regulation of Phosphorylation of TXK 4 0.06 1.42 0.37
16 INT192347 Phosphorylation of TXK 12 0.22 6.71 0.36
17 INT233845 Negative_regulation of Itk 7 0.18 4.81 0.22
18 INT279293 Localization of TXK 3 0.18 1.52 0.22
19 INT277845 Negative_regulation of Gene_expression of TXK 2 0.04 0.92 0.16
20 INT285096 Transcription of ITK 1 0.17 0.77 0.1
21 INT276373 Localization of ITK 1 0.78 1.42 0.08
22 INT285664 Regulation of Itk 3 0.05 1.66 0.07
23 INT331613 Regulation of Positive_regulation of Itk 1 0.02 0.87 0.06
24 INT176589 Negative_regulation of Binding of TXK 6 0.09 2.06 0.05
25 INT285094 Binding of ITK 4 0.11 2.14 0.05
26 INT269229 Regulation of ITK 3 0.10 3.62 0.05
27 INT307937 Negative_regulation of Positive_regulation of Itk 1 0.18 2.5 0.05
28 INT269221 Regulation of Positive_regulation of ITK 1 0.07 0.91 0.03
29 INT279299 Positive_regulation of Localization of TXK 1 0.12 0.5 0.03
30 INT324054 Negative_regulation of Gene_expression of Itk 1 0.08 0.39 0
31 INT266933 Regulation of Gene_expression of TXK 1 0.08 0.31 0
32 INT307933 Binding of Itk 1 0.15 0.71 0
33 INT326710 Regulation of Gene_expression of Itk 1 0.03 0.06 0
34 INT266929 Positive_regulation of Negative_regulation of TXK 1 0.07 0.2 0
35 INT307934 Localization of Itk 1 0.36 2.65 0
36 INT279300 Negative_regulation of Phosphorylation of TXK 1 0.11 0.92 0
37 INT176568 Protein_catabolism of TXK 1 0.01 0.13 0
38 INT266930 Positive_regulation of Positive_regulation of TXK 1 0.12 0 0
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