GO:0001867

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Name complement activation, lectin pathway
Categary Process
Go Slim No
Go Link GO:0001867
Unique Molecular Interactions 52
Total Molecular Interactions 63
Total Single Events 612
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for complement activation, lectin pathway. They are ordered first by their pain relevance and then by number of times they were reported for complement activation, lectin pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT239064 Binding of Mbl1 and IgG 1 0.03 2.59 0.78
2 INT299745 Binding of Masp1 and IgG 1 0.03 0.69 0.26
3 INT281042 Serping1 Regulation of MBL2 1 0.01 0.74 0.11
4 INT306452 Binding of MBL2 and TLR4 1 0.38 0.37 0.1
5 INT306453 MBL2 Regulation of Binding of TLR4 1 0.48 0.37 0.1
6 INT281029 MASP2 Positive_regulation of C4A 1 0.00 0.72 0.1
7 INT97314 Binding of ETFA and KRT1 1 0.07 0.75 0.08
8 INT332017 Binding of Ighm and Mbl1 1 0.11 0.26 0.06
9 INT344225 Binding of fc and Krt1 1 0.00 0.39 0.06
10 INT279531 Binding of LPA and MBL2 1 0.02 0.54 0.04
11 INT339708 MBL2 Regulation of MAP3K2 1 0.00 0.1 0
12 INT344223 Positive_regulation of Binding of fc and Krt1 1 0.00 0 0
13 INT279535 Binding of C1QC and MBL2 1 0.01 2.79 0
14 INT279530 MBL2 Positive_regulation of Positive_regulation of C3 1 0.26 1.71 0
15 INT289408 Binding of Masp1 and Masp2 1 0.07 0.06 0
16 INT281041 Binding of MASP2 and Serping1 1 0.00 1.2 0
17 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0
18 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0
19 INT279539 Binding of CFD and MBL2 1 0.09 0.08 0
20 INT344221 Binding of C4bp and Krt1 1 0.01 0.5 0
21 INT221124 Binding of KRT1 and IGKV1-22 1 0.02 0 0
22 INT344227 Binding of C4b and Krt1 1 0.01 0.51 0
23 INT186548 Binding of KRT1 and MAX 1 0.01 0.15 0
24 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0
25 INT339704 MBL2 Regulation of SGK2 1 0.06 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for complement activation, lectin pathway. They are ordered first by their pain relevance and then by number of times they were reported in complement activation, lectin pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT239050 Negative_regulation of Mbl1 1 0.45 15 4.24
2 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12
3 INT146693 Gene_expression of Mbl1 17 0.59 10.99 3.13
4 INT35242 Negative_regulation of MBL2 17 0.48 12.53 1.73
5 INT247102 Binding of MBL2 16 0.38 14.18 1.54
6 INT279572 Gene_expression of MBL2 27 0.64 20.88 1.51
7 INT239060 Binding of Mbl1 5 0.32 4.89 1.27
8 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16
9 INT41873 Positive_regulation of Mbl1 4 0.39 2.1 0.9
10 INT11919 Regulation of KRT1 9 0.10 4.97 0.77
11 INT34723 Regulation of Mbl1 2 0.41 2.26 0.63
12 INT281033 Regulation of MBL2 6 0.34 4.96 0.52
13 INT70445 Binding of KRT1 10 0.35 5.38 0.47
14 INT29637 Localization of KRT1 6 0.20 5.55 0.4
15 INT35901 Positive_regulation of Masp1 1 0.00 0.53 0.35
16 INT239056 Transcription of Mbl1 1 0.46 0.94 0.29
17 INT306469 Negative_regulation of Gene_expression of MBL2 1 0.40 1.72 0.29
18 INT289396 Binding of Masp1 3 0.19 0.8 0.26
19 INT299742 Gene_expression of Masp1 1 0.12 0.68 0.26
20 INT239058 Negative_regulation of Negative_regulation of Mbl1 1 0.29 0.57 0.22
21 INT306468 Positive_regulation of Gene_expression of MBL2 7 0.47 4.3 0.17
22 INT341341 Regulation of Gene_expression of MBL2 1 0.18 0.58 0.1
23 INT322065 Localization of MBL2 1 0.56 1.34 0.1
24 INT281031 Localization of MASP2 1 0.04 0.72 0.1
25 INT279580 Positive_regulation of Binding of MBL2 4 0.48 2.15 0.08
26 INT306465 Negative_regulation of MASP2 1 0.34 1.3 0.08
27 INT306472 Positive_regulation of Negative_regulation of MASP2 1 0.40 1.31 0.08
28 INT344213 Binding of Krt1 1 0.03 2.24 0.08
29 INT103445 Gene_expression of Krt1 2 0.15 2.03 0.07
30 INT175895 Negative_regulation of KRT1 5 0.37 3.23 0.05
31 INT306467 Transcription of MBL2 1 0.44 0.7 0.05
32 INT281035 Regulation of MASP2 1 0.03 0.22 0.04
33 INT221854 Regulation of Positive_regulation of KRT1 1 0.03 0.86 0.04
34 INT281032 Gene_expression of MASP2 2 0.48 0.67 0.03
35 INT306473 Negative_regulation of Binding of MBL2 1 0.36 0.07 0.03
36 INT279576 Positive_regulation of MBL2 4 0.38 4.1 0
37 INT303344 Localization of Krt1 2 0.20 0 0
38 INT289384 Binding of Masp2 1 0.19 0.12 0
39 INT344206 Positive_regulation of Krt1 1 0.03 0.81 0
40 INT344198 Negative_regulation of Localization of Krt1 1 0.02 0 0
41 INT232879 Protein_catabolism of KRT1 1 0.64 0.92 0
42 INT303378 Regulation of Krt1 1 0.12 0 0
43 INT344210 Positive_regulation of Gene_expression of Krt1 1 0.03 0.43 0
44 INT344203 Transcription of Krt1 1 0.04 0 0
45 INT281034 Binding of MASP2 1 0.02 0.34 0
46 INT344195 Positive_regulation of Positive_regulation of Krt1 1 0.03 0.41 0
47 INT344215 Protein_catabolism of Krt1 1 0.04 0 0
48 INT239057 Negative_regulation of Gene_expression of Mbl1 1 0.28 0.05 0
49 INT344207 Negative_regulation of Binding of Krt1 1 0.02 0 0
50 INT188175 Positive_regulation of Gene_expression of KRT1 1 0.06 0.16 0
51 INT344216 Positive_regulation of Binding of Krt1 1 0.03 0.41 0
52 INT299636 Protein_catabolism of Masp2 1 0.28 0.07 0
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