GO:0001869

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Name negative regulation of complement activation, lectin pathway
Categary Process
Go Slim No
Go Link GO:0001869
Unique Molecular Interactions 34
Total Molecular Interactions 41
Total Single Events 710
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of complement activation, lectin pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of complement activation, lectin pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
2 INT106074 IL1B Positive_regulation of Gene_expression of A2M 1 0.03 0.75 0.49
3 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49
4 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32
5 INT94849 A2M Negative_regulation of Gene_expression of COL7A1 1 0.01 0.27 0.28
6 INT24222 Ifng Positive_regulation of Gene_expression of Serping1 1 0.00 0 0.26
7 INT41950 Ptger1 Positive_regulation of Localization of A2m 1 0.19 0.46 0.24
8 INT41949 Ptger1 Positive_regulation of Gene_expression of A2m 1 0.19 0.46 0.24
9 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19
10 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19
11 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18
12 INT131304 Binding of Serping1 and Sele 1 0.01 1.07 0.15
13 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14
14 INT94850 A2M Negative_regulation of Gene_expression of PIP 1 0.01 0.14 0.14
15 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12
16 INT281042 Serping1 Regulation of MBL2 1 0.01 0.74 0.11
17 INT279511 Binding of Serping1 and C1ra 1 0.01 0.3 0.11
18 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1
19 INT232011 SERPING1 Regulation of Negative_regulation of SERPINE1 1 0.01 0.45 0.07
20 INT251645 Binding of SERPING1 and CD79A 1 0.10 1.31 0.06
21 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04
22 INT232013 SERPING1 Negative_regulation of C1S 1 0.24 0.72 0.04
23 INT232012 SERPING1 Negative_regulation of C1R 1 0.18 0.72 0.04
24 INT349287 A2m Negative_regulation of Prtn3 1 0.00 0.4 0.03
25 INT232016 SERPING1 Regulation of C1S 1 0.15 0.57 0
26 INT127731 Binding of A2m and Mif 1 0.19 0 0
27 INT281041 Binding of MASP2 and Serping1 1 0.00 1.2 0
28 INT310200 Binding of Serping1 and F12 1 0.21 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of complement activation, lectin pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of complement activation, lectin pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17
2 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92
3 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75
4 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75
5 INT41942 Gene_expression of A2m 9 0.36 9.98 3.96
6 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75
7 INT64843 Gene_expression of Serping1 19 0.67 8.88 2.72
8 INT156130 Binding of SERPING1 29 0.42 26.16 2.52
9 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5
10 INT4585 Gene_expression of Serping1 19 0.46 12.4 2.35
11 INT23352 Negative_regulation of A2M 10 0.33 8.35 2.16
12 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14
13 INT40954 Regulation of Serping1 5 0.32 3.71 1.88
14 INT41639 Positive_regulation of A2m 7 0.46 4.52 1.74
15 INT3249 Regulation of A2M 7 0.39 3.29 1.61
16 INT41944 Positive_regulation of Gene_expression of A2m 2 0.23 2.56 1.29
17 INT156672 Localization of SERPING1 10 0.74 12.15 1.25
18 INT41947 Regulation of A2m 2 0.29 1.08 1.14
19 INT86931 Gene_expression of A2m 3 0.16 4.81 1.04
20 INT144482 Negative_regulation of Gene_expression of SERPING1 8 0.43 6.06 0.89
21 INT41946 Localization of A2m 1 0.38 1.81 0.89
22 INT74260 Positive_regulation of Serping1 5 0.64 6.05 0.8
23 INT41943 Positive_regulation of Positive_regulation of A2m 2 0.22 1.19 0.74
24 INT146109 Positive_regulation of Serping1 4 0.59 2.73 0.68
25 INT41945 Negative_regulation of A2m 2 0.27 0.35 0.68
26 INT189322 Binding of A2M 7 0.29 12.1 0.66
27 INT146108 Regulation of Positive_regulation of Serping1 1 0.05 1.04 0.6
28 INT81371 Binding of Serping1 3 0.37 2.67 0.55
29 INT167366 Positive_regulation of A2m 1 0.02 0.43 0.49
30 INT94026 Regulation of SERPING1 12 0.61 10.28 0.37
31 INT288336 Positive_regulation of Gene_expression of A2m 1 0.12 1.73 0.37
32 INT64842 Negative_regulation of Gene_expression of Serping1 2 0.35 0.56 0.36
33 INT48772 Localization of A2M 3 0.78 2.83 0.35
34 INT316315 Negative_regulation of Binding of SERPING1 2 0.37 1.4 0.34
35 INT232021 Positive_regulation of Gene_expression of SERPING1 8 0.49 4.99 0.31
36 INT131301 Binding of Serping1 3 0.28 1.86 0.3
37 INT4586 Negative_regulation of Gene_expression of Serping1 3 0.30 2.12 0.28
38 INT142433 Regulation of Serping1 1 0.00 0 0.25
39 INT311965 Positive_regulation of Gene_expression of Serping1 2 0.16 1.33 0.24
40 INT46524 Negative_regulation of Gene_expression of A2M 2 0.02 1.45 0.23
41 INT41948 Negative_regulation of Localization of A2m 1 0.20 0.46 0.23
42 INT228644 Positive_regulation of Negative_regulation of SERPING1 5 0.46 4.21 0.21
43 INT3248 Positive_regulation of Positive_regulation of A2M 1 0.46 0.25 0.17
44 INT23708 Regulation of Regulation of A2M 1 0.02 0.68 0.17
45 INT232025 Regulation of Gene_expression of SERPING1 3 0.56 1.75 0.15
46 INT167367 Binding of A2m 1 0.01 0.13 0.15
47 INT316318 Phosphorylation of SERPING1 2 0.81 1.7 0.13
48 INT193490 Negative_regulation of Gene_expression of A2m 1 0.06 0.56 0.1
49 INT37864 Regulation of Negative_regulation of Serping1 1 0.10 0.69 0.09
50 INT232027 Positive_regulation of Positive_regulation of SERPING1 2 0.46 1.48 0.08
51 INT310196 Localization of Serping1 2 0.39 2.64 0.04
52 INT199219 Negative_regulation of Positive_regulation of A2M 1 0.29 1.94 0.03
53 INT279452 Negative_regulation of Negative_regulation of Serping1 1 0.06 0.3 0.03
54 INT45413 Transcription of Serping1 1 0.68 0.9 0
55 INT236257 Regulation of Gene_expression of A2m 1 0.14 0 0
56 INT326636 Positive_regulation of Gene_expression of Serping1 1 0.23 0.54 0
57 INT111831 Positive_regulation of Positive_regulation of Serping1 1 0.64 0 0
58 INT328285 Negative_regulation of Localization of SERPING1 1 0.37 0.95 0
59 INT204875 Negative_regulation of Positive_regulation of SERPING1 1 0.42 0.1 0
60 INT281038 Positive_regulation of Negative_regulation of Serping1 1 0.10 2.63 0
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