GO:0001889

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Name liver development
Categary Process
Go Slim No
Go Link GO:0001889
Unique Molecular Interactions 1162
Total Molecular Interactions 1683
Total Single Events 13450
Pain Genes Associated 110

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for liver development. They are ordered first by their pain relevance and then by number of times they were reported for liver development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
3 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
4 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
5 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
6 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
7 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
8 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
9 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
10 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
11 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
12 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
13 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
14 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
15 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
16 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
17 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
18 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
19 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
20 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
21 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
22 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
23 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
24 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
25 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
26 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
27 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
28 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
29 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
30 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
31 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
32 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
33 INT25837 Binding of Dbp and Oprl1 1 0.10 0 1.05
34 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
35 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04
36 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
37 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
38 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
39 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
40 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
41 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
42 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
43 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
44 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
45 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
46 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
47 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
48 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
49 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
50 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
51 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
52 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
53 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
54 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
55 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
56 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
57 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94
58 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
59 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
60 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
61 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
62 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
63 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
64 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
65 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
66 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
67 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
68 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
69 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
70 INT25239 Ugt1a2 Positive_regulation of Ugt2b 1 0.30 0 0.85
71 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
72 INT151409 Binding of Cp and Cd8b 1 0.16 0 0.84
73 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
74 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
75 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
76 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
77 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
78 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
79 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 0.00 0.07 0.77
80 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
81 INT104748 Ugt1a1 Regulation of Positive_regulation of LOC100359830 1 0.01 0.07 0.77
82 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
83 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
84 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
85 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
86 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
87 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
88 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
89 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
90 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
91 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
92 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
93 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
94 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
95 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
96 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
97 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
98 INT326457 Runx1 Regulation of Mrgpra3 1 0.37 0.1 0.71
99 INT326456 Runx1 Regulation of Pip4k2b 1 0.09 0.11 0.71
100 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
101 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
102 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
103 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
104 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
105 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
106 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
107 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
108 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
109 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
110 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
111 INT172698 Ugt1a6 Negative_regulation of Localization of Acot1 1 0.01 0 0.68
112 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
113 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
114 INT94241 Binding of Cp and Slc2a2 1 0.13 0.81 0.67
115 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
116 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
117 INT335456 Binding of PDX1 and hb 1 0.02 2.59 0.66
118 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
119 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
120 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
121 INT98955 Positive_regulation of Binding of SP3 and CFHR4 1 0.00 0 0.62
122 INT182156 Binding of HGF and IL3RA 1 0.03 1.31 0.62
123 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
124 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
125 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
126 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
127 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
128 INT98952 Binding of SP3 and CFHR4 1 0.00 0 0.61
129 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
130 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
131 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
132 INT73654 Binding of Jun and Pim3 1 0.02 0.99 0.58
133 INT94240 Binding of Cp and Ins1 1 0.02 0.7 0.58
134 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
135 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
136 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
137 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
138 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
139 INT73368 Ang1 Negative_regulation of Fabp6 1 0.00 0.44 0.56
140 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
141 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
142 INT60481 Binding of Ugt1a1 and UGT1A6 1 0.23 0 0.55
143 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
144 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
145 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
146 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
147 INT10079 Cp Regulation of Trh 1 0.01 0.59 0.53
148 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
149 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
150 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
151 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
152 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
153 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
154 INT138353 Foxm1 Positive_regulation of Phosphorylation of Trpv1 1 0.10 0.31 0.51
155 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
156 INT138352 Foxm1 Positive_regulation of Trpa1 1 0.05 0.33 0.51
157 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
158 INT352521 Cnn1 Positive_regulation of Cp 1 0.00 1.45 0.5
159 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
160 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
161 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
162 INT86088 Foxm1 Positive_regulation of Binding of Crygs 1 0.04 0 0.49
163 INT98734 Egf Negative_regulation of Tk1 1 0.13 0.15 0.49
164 INT86089 Foxm1 Regulation of Binding of Crygs 1 0.02 0 0.49
165 INT107803 Ugt1a5 Positive_regulation of Prl 2 0.44 0.48 0.48
166 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
167 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
168 INT58663 Binding of KNG1 and Ugt1a2 1 0.02 0.4 0.47
169 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47
170 INT102556 HGF Positive_regulation of Phosphorylation of ELK1 1 0.10 0.46 0.47
171 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
172 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
173 INT177784 PDCD2 Positive_regulation of ASNS 1 0.04 0.76 0.46
174 INT296114 Il4 Regulation of Gene_expression of Arg1 1 0.00 0.65 0.46
175 INT39870 Odc1 Negative_regulation of Tk1 1 0.36 0.8 0.46
176 INT233668 Cebpd Negative_regulation of Cebpg 1 0.43 0.66 0.46
177 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
178 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
179 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
180 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
181 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
182 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
183 INT349853 Binding of Hspb1 and Jun 1 0.14 2.3 0.45
184 INT80053 Negative_regulation of Binding of ACAT1 and NA 1 0.01 0.25 0.45
185 INT247639 Binding of Jun and Atf3 2 0.09 3.06 0.44
186 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
187 INT256356 Binding of Nfkb1 and Rela 1 0.21 0 0.44
188 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
189 INT80052 Binding of ACAT1 and NA 1 0.01 0.24 0.44
190 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
191 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
192 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
193 INT103132 Positive_regulation of DCSTAMP Positive_regulation of JUN 1 0.03 0.73 0.43
194 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43
195 INT127074 Gdnf Regulation of Gene_expression of Jun 1 0.10 0.28 0.43
196 INT127075 Bdnf Regulation of Gene_expression of Jun 1 0.11 0.28 0.43
197 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43
198 INT326458 Runx1 Negative_regulation of Gene_expression of Calca 1 0.18 0.05 0.43
199 INT298287 Runx1 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
200 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43

Single Events

The table below shows the top 100 pain related interactions that have been reported for liver development. They are ordered first by their pain relevance and then by number of times they were reported in liver development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
2 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
3 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
4 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
5 INT47764 Binding of Jun 106 0.48 22.62 31.39
6 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
7 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
8 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
9 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
10 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
11 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
12 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
13 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
14 INT2432 Positive_regulation of Cp 41 0.67 31.1 16.68
15 INT41558 Localization of Sp1 9 0.48 0.56 14.9
16 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
17 INT93482 Localization of Rela 56 0.78 24.52 14.82
18 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
19 INT2758 Binding of Dbp 36 0.44 8.3 14.47
20 INT17593 Regulation of Jun 37 0.60 5.5 14.35
21 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43
22 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
23 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25
24 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
25 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
26 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
27 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
28 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99
29 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
30 INT52233 Transcription of Jun 37 0.66 6.39 11.15
31 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
32 INT192967 Gene_expression of Hp 14 0.43 8.06 11.01
33 INT273123 Binding of Hp 1 0.25 3.56 10.9
34 INT27687 Regulation of Cp 20 0.53 9.75 10.8
35 INT60198 Binding of JUN 54 0.48 11.56 10.27
36 INT133210 Positive_regulation of Runx1 33 0.69 18.25 10.12
37 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
38 INT245538 Negative_regulation of Gene_expression of Runx1 20 0.58 11.68 9.97
39 INT149138 Binding of PDX1 27 0.37 32.62 9.33
40 INT25834 Positive_regulation of Dbp 59 0.68 24.34 9.32
41 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
42 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19
43 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
44 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
45 INT66213 Localization of RELA 63 0.78 14.71 8.77
46 INT61264 Regulation of Jun 36 0.61 18.42 8.71
47 INT64815 Binding of Jun 49 0.48 21.47 8.59
48 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4
49 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39
50 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37
51 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
52 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
53 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97
54 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
55 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84
56 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
57 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67
58 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
59 INT64816 Transcription of Jun 31 0.69 16.01 7.64
60 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
61 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
62 INT10344 Localization of Jun 23 0.73 6.36 7.46
63 INT70252 Gene_expression of Ugt1a6 20 0.77 3.89 7.45
64 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28
65 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
66 INT75497 Regulation of JUN 28 0.61 11.04 7.09
67 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
68 INT47540 Binding of Cp 20 0.41 15.54 7.01
69 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
70 INT18778 Gene_expression of Ugt1a2 17 0.35 9.91 6.87
71 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
72 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68
73 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
74 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
75 INT48555 Binding of SP1 30 0.46 11.38 6.53
76 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
77 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
78 INT86805 Localization of HGF 49 0.71 28.48 6.35
79 INT13683 Regulation of Ugt1a6 9 0.28 2.5 6.33
80 INT169596 Transcription of Runx1 12 0.71 5.55 6.27
81 INT245515 Regulation of Runx1 14 0.61 5.07 6.22
82 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
83 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
84 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
85 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
86 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
87 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
88 INT60475 Gene_expression of Ugt1a1 17 0.77 4.26 5.62
89 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59
90 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
91 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
92 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
93 INT35928 Positive_regulation of Baat 12 0.69 12.23 5.43
94 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
95 INT10888 Binding of Vwf 32 0.46 22.87 5.21
96 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
97 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
98 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
99 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
100 INT36256 Regulation of Ada 9 0.62 4.99 5.07
101 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06
102 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
103 INT245536 Regulation of Gene_expression of Runx1 11 0.58 6.22 4.88
104 INT28176 Localization of Cp 17 0.73 14.3 4.86
105 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
106 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66
107 INT68216 Binding of NF1 40 0.48 51.24 4.59
108 INT2213 Regulation of EP300 10 0.54 4.72 4.5
109 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
110 INT29231 Regulation of Dbp 44 0.53 10.08 4.47
111 INT198736 Binding of Sp3 23 0.40 4.77 4.42
112 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
113 INT28030 Binding of Otc 5 0.37 2.72 4.3
114 INT20052 Negative_regulation of UGT1A1 12 0.58 4.51 4.29
115 INT7725 Positive_regulation of Hgf 9 0.67 3.62 4.25
116 INT745 Gene_expression of Afp 65 0.78 52.89 4.24
117 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
118 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
119 INT67936 Transcription of JUN 18 0.52 9.52 4.13
120 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
121 INT192970 Negative_regulation of Hp 7 0.22 6.99 4.06
122 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
123 INT127681 Binding of Ugt1a6 7 0.47 0.79 4
124 INT134590 Localization of ADA 7 0.65 8.43 3.96
125 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
126 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
127 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
128 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
129 INT38033 Regulation of HGF 26 0.45 14.96 3.81
130 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
131 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
132 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
133 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
134 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
135 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
136 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
137 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69
138 INT187 Positive_regulation of Ephx1 17 0.69 0.51 3.69
139 INT15776 Localization of Jun 10 0.74 3.9 3.69
140 INT39199 Positive_regulation of Ugt1a1 9 0.45 1.78 3.69
141 INT78514 Gene_expression of Cast 6 0.64 4.48 3.69
142 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
143 INT21869 Negative_regulation of Otc 16 0.58 8.43 3.67
144 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
145 INT17716 Gene_expression of Aldh2 14 0.77 4.38 3.61
146 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
147 INT195527 Binding of Rela 17 0.25 4.42 3.56
148 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
149 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
150 INT59662 Localization of Ugt1a6 4 0.71 0.44 3.52
151 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48
152 INT13878 Negative_regulation of Ugt1a2 9 0.33 2.85 3.48
153 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
154 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
155 INT74946 Negative_regulation of Gene_expression of HGF 14 0.58 6.29 3.39
156 INT72798 Binding of ADA 12 0.47 7.84 3.39
157 INT133214 Regulation of PDX1 9 0.34 10.26 3.36
158 INT45324 Positive_regulation of Otc 8 0.59 3.94 3.36
159 INT65120 Regulation of Ugt1a1 3 0.45 1.07 3.29
160 INT184 Regulation of Ephx1 10 0.60 0.54 3.27
161 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
162 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
163 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
164 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
165 INT133557 Transcription of Rela 6 0.52 3.86 3.2
166 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17
167 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
168 INT123409 Binding of Sp1 20 0.39 3.18 3.15
169 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
170 INT8477 Negative_regulation of AFP 35 0.58 31.52 3.1
171 INT24873 Binding of KLF1 12 0.07 6.73 3.1
172 INT34604 Binding of Ada 11 0.31 4.15 3.1
173 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
174 INT9766 Positive_regulation of Ada 2 0.47 0.4 3.09
175 INT55409 Localization of VWF 17 0.80 8.99 3.06
176 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
177 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
178 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97
179 INT131494 Regulation of ADA 8 0.52 7.37 2.97
180 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
181 INT103607 Binding of Sp1 7 0.42 1.26 2.92
182 INT220335 Gene_expression of UROD 34 0.54 24.53 2.89
183 INT15288 Regulation of Hp 11 0.60 3.68 2.89
184 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
185 INT8670 Negative_regulation of Afp 27 0.58 19.85 2.87
186 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
187 INT10893 Binding of VWF 27 0.47 25.02 2.82
188 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
189 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
190 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
191 INT64819 Positive_regulation of Transcription of Jun 6 0.50 4.41 2.79
192 INT10516 Localization of Vwf 30 0.79 7.54 2.77
193 INT192964 Positive_regulation of Hp 7 0.28 2 2.75
194 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
195 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72
196 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
197 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
198 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
199 INT89336 Binding of SP3 6 0.47 1.75 2.63
200 INT34114 Positive_regulation of Ugt1a7c 4 0.56 1.94 2.61
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