GO:0001892

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Name embryonic placenta development
Categary Process
Go Slim No
Go Link GO:0001892
Unique Molecular Interactions 764
Total Molecular Interactions 1039
Total Single Events 8955
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryonic placenta development. They are ordered first by their pain relevance and then by number of times they were reported for embryonic placenta development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
2 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
3 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
4 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
5 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
6 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
7 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
8 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44
9 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
10 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
11 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
12 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
13 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
14 INT51388 Binding of CSF2 and RPLP0 1 0.11 1.8 1.27
15 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25
16 INT62018 CSF2 Regulation of ACOT1 1 0.12 0.47 1.21
17 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
18 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18
19 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18
20 INT282712 Binding of MUC5AC and Csf2 1 0.01 2.63 1.07
21 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
22 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05
23 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
24 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
25 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
26 INT48381 CSF2 Positive_regulation of ITGAM 2 0.30 0.38 0.95
27 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
28 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
29 INT45279 Binding of CSF2 and GHR 1 0.05 0.07 0.93
30 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
31 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
32 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
33 INT82120 IK Positive_regulation of CEBPB 1 0.00 0 0.92
34 INT124742 ARSA Positive_regulation of Localization of CSF2 1 0.10 0.15 0.91
35 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
36 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
37 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
38 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
39 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
40 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
41 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
42 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
43 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88
44 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
45 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
46 INT48384 CSF2 Regulation of Gene_expression of SELL 1 0.17 0.4 0.83
47 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
48 INT131793 Binding of Slco1c1 and Csf2 1 0.02 0 0.81
49 INT131794 Binding of Csf2 and Gpm6a 1 0.17 0 0.81
50 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
51 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75
52 INT170658 Binding of Ntf3 and Csf2 1 0.33 0.8 0.74
53 INT75937 MLXIPL Regulation of Csf2 1 0.01 0.68 0.74
54 INT209037 Il4 Positive_regulation of Csf2 1 0.03 0.38 0.73
55 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73
56 INT209062 Il3 Positive_regulation of Csf2 1 0.02 0.38 0.73
57 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72
58 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
59 INT209045 Il10 Positive_regulation of Csf2 1 0.03 0.37 0.72
60 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
61 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
62 INT48387 CSF2 Positive_regulation of SELL 1 0.18 0.24 0.71
63 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
64 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
65 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
66 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
67 INT48386 CSF2 Positive_regulation of Positive_regulation of ITGAM 1 0.16 0.24 0.7
68 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
69 INT48385 CSF2 Regulation of Gene_expression of ITGAM 2 0.16 0.29 0.68
70 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
71 INT75936 Csf2 Positive_regulation of Oprk1 1 0.25 0.78 0.67
72 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
73 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
74 INT76877 Binding of Slc3a1 and Slc8a1 1 0.02 0 0.64
75 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
76 INT98955 Positive_regulation of Binding of SP3 and CFHR4 1 0.00 0 0.62
77 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
78 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
79 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
80 INT98952 Binding of SP3 and CFHR4 1 0.00 0 0.61
81 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
82 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59
83 INT81915 HSF1 Negative_regulation of IL1B 1 0.51 0.65 0.59
84 INT45496 Binding of CSF2 and C6orf25 1 0.03 1.08 0.59
85 INT81917 HSF1 Positive_regulation of IL1B 1 0.41 0.65 0.59
86 INT172145 IL10 Negative_regulation of Gene_expression of CSF2 1 0.04 0.69 0.59
87 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59
88 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58
89 INT149480 CEBPD Positive_regulation of CEBPB 1 0.50 0.15 0.58
90 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
91 INT184242 Mthfd1 Negative_regulation of Gene_expression of Csf2 1 0.03 0.87 0.56
92 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
93 INT176340 CHI3L1 Positive_regulation of Localization of CSF2 1 0.11 1.86 0.55
94 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54
95 INT282711 Binding of Csf2 and Mmp9 1 0.16 1.35 0.54
96 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
97 INT194915 Csf2 Positive_regulation of Gene_expression of Mmp1a 1 0.01 0.85 0.52
98 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
99 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
100 INT263976 Binding of CSF2 and FPR2 1 0.07 0.81 0.51
101 INT263973 Binding of CSF2 and FPR1 1 0.08 0.81 0.51
102 INT340212 Csf2 Positive_regulation of Pttg1ip 1 0.02 0.46 0.49
103 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
104 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
105 INT48382 CSF2 Positive_regulation of Gene_expression of ITGAM 1 0.23 0.25 0.49
106 INT135584 CSF2 Regulation of PTGS2 1 0.06 1.28 0.49
107 INT135591 CSF2 Regulation of IL8 1 0.09 1.27 0.48
108 INT48379 CSF2 Negative_regulation of Gene_expression of SELL 1 0.22 0.2 0.48
109 INT68691 Positive_regulation of Binding of CSF2 and IL3 1 0.49 2.63 0.48
110 INT135589 CSF2 Regulation of IL6 1 0.08 1.27 0.48
111 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
112 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
113 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
114 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45
115 INT236832 CSF2 Regulation of CXCL13 1 0.09 0.34 0.45
116 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45
117 INT48383 CSF2 Regulation of Gene_expression of ITGB2 1 0.11 0.2 0.44
118 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44
119 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
120 INT80415 Binding of Csf2 and Gnptab 1 0.02 0 0.43
121 INT170657 Ntf3 Regulation of Csf2 1 0.31 0.46 0.43
122 INT170157 NPPC Regulation of CSF2 1 0.12 1.36 0.42
123 INT118519 Slc8a1 Negative_regulation of Positive_regulation of Nfkb1 1 0.16 0.59 0.42
124 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
125 INT41657 IL31RA Positive_regulation of CSF2 1 0.22 0.4 0.41
126 INT95206 Binding of CSF2 and IL2 1 0.40 1.81 0.4
127 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
128 INT181443 Csf2 Positive_regulation of Cxcl10 1 0.02 1.69 0.39
129 INT345006 CSF2 Regulation of GSN 1 0.16 0.82 0.39
130 INT36914 PPAP2A Regulation of Positive_regulation of CSF2 1 0.02 0.16 0.39
131 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39
132 INT345007 CSF2 Regulation of DBP 1 0.14 0.82 0.39
133 INT245503 SST Regulation of Gene_expression of CSF2 1 0.06 0.67 0.39
134 INT200313 Sp3 Regulation of Oprm1 1 0.10 0.07 0.38
135 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38
136 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
137 INT200301 Sp3 Regulation of Rorb 1 0.00 0.07 0.38
138 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
139 INT202810 Pin1 Regulation of Csf2 1 0.03 0.82 0.36
140 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
141 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36
142 INT167551 Binding of MECP2 and SP3 1 0.01 0.06 0.35
143 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
144 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
145 INT165305 CSF2 Positive_regulation of Localization of CCBE1 1 0.06 1.34 0.35
146 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
147 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
148 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34
149 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33
150 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
151 INT244325 Csf2 Regulation of Positive_regulation of Aliq1 1 0.03 1.02 0.33
152 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33
153 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33
154 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32
155 INT253576 Binding of Lpl and Sp3 1 0.22 0.85 0.32
156 INT303106 CAMK4 Positive_regulation of Csf2 1 0.26 0.17 0.31
157 INT85119 CSF2 Regulation of CDCP1 1 0.01 0.66 0.31
158 INT85118 CSF2 Regulation of Gene_expression of CDCP1 1 0.00 0.66 0.31
159 INT85116 CSF2 Regulation of IL3 1 0.05 0.6 0.3
160 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
161 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
162 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
163 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
164 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
165 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29
166 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
167 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29
168 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29
169 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
170 INT166093 Negative_regulation of ROS1 Negative_regulation of Positive_regulation of EGFR 1 0.12 0.33 0.28
171 INT327337 MIR29A Negative_regulation of Ttpa 1 0.04 1.14 0.28
172 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
173 INT166094 Negative_regulation of CSK Negative_regulation of Positive_regulation of EGFR 1 0.02 0.33 0.28
174 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 0.07 0.37 0.28
175 INT329529 Tnfaip8 Positive_regulation of Gene_expression of Csf2 1 0.07 0.35 0.28
176 INT213816 Binding of Tcf12 and Tfeb 1 0.01 1.91 0.27
177 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
178 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
179 INT118928 Csf2 Regulation of Cpe 1 0.04 0.27 0.27
180 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27
181 INT172140 CSF2 Positive_regulation of Gene_expression of TIMP1 1 0.07 0.72 0.27
182 INT96787 SP1 Positive_regulation of GDF15 1 0.08 0.27 0.27
183 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
184 INT213799 Sh2b2 Regulation of Tfeb 1 0.26 0.54 0.27
185 INT96790 SP3 Positive_regulation of GDF15 1 0.20 0.26 0.27
186 INT125515 SP1 Regulation of GDF15 1 0.14 0.47 0.26
187 INT311046 Binding of CSF2 and IL33 1 0.00 1.86 0.26
188 INT169837 Sp1 Positive_regulation of Gene_expression of Kcnq3 1 0.04 0.08 0.26
189 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
190 INT345008 Binding of ACTN1 and CSF2 1 0.02 0.53 0.26
191 INT123468 IL6 Regulation of CSF2 1 0.25 1.22 0.26
192 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
193 INT169836 Sp1 Positive_regulation of Gene_expression of Kcnq2 1 0.05 0.08 0.26
194 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
195 INT209879 CSF2 Positive_regulation of Gene_expression of TNFRSF11B 1 0.10 0.76 0.26
196 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
197 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25
198 INT164636 Negative_regulation of CSF2 Positive_regulation of ITGAM 1 0.26 0.14 0.25
199 INT355983 CSF2 Regulation of Gene_expression of DCPS 1 0.02 0.84 0.25
200 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryonic placenta development. They are ordered first by their pain relevance and then by number of times they were reported in embryonic placenta development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89
2 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73
3 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32
4 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77
5 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07
6 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22
7 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44
8 INT14690 Localization of CSF2 124 0.80 85.17 27.26
9 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
10 INT11685 Regulation of CSF2 99 0.59 58.82 15.9
11 INT41558 Localization of Sp1 9 0.48 0.56 14.9
12 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
13 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24
14 INT18720 Localization of Csf2 72 0.67 13.65 13.41
15 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
16 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
17 INT3521 Regulation of Csf2 38 0.54 11.09 12.73
18 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
19 INT9945 Negative_regulation of Csf2 35 0.51 17.85 11.22
20 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
21 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
22 INT25381 Localization of Csf2 62 0.76 47.48 9.03
23 INT14301 Binding of CSF2 82 0.48 67.95 8.98
24 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
25 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36
26 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32
27 INT75932 Binding of Csf2 45 0.37 33.2 8.01
28 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
29 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
30 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88
31 INT48555 Binding of SP1 30 0.46 11.38 6.53
32 INT11154 Binding of EGFR 149 0.48 96.23 6.29
33 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28
34 INT46721 Regulation of Csf2 26 0.45 20.4 6.18
35 INT48393 Positive_regulation of Localization of CSF2 14 0.60 8.92 6.1
36 INT3520 Binding of Csf2 27 0.43 9.68 6.08
37 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
38 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
39 INT25394 Negative_regulation of Gene_expression of Csf2 22 0.52 13.18 5.84
40 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
41 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
42 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
43 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
44 INT198736 Binding of Sp3 23 0.40 4.77 4.42
45 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
46 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
47 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
48 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
49 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
50 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
51 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
52 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
53 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
54 INT279383 Negative_regulation of Ttpa 2 0.06 16.02 3.37
55 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28
56 INT66919 Positive_regulation of HSF1 27 0.69 14.78 3.24
57 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
58 INT151123 Negative_regulation of Gene_expression of Csf2 21 0.53 21.76 3.22
59 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
60 INT123409 Binding of Sp1 20 0.39 3.18 3.15
61 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
62 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
63 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
64 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
65 INT103607 Binding of Sp1 7 0.42 1.26 2.92
66 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
67 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
68 INT68576 Positive_regulation of Positive_regulation of CSF2 8 0.40 8.1 2.83
69 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69
70 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
71 INT89336 Binding of SP3 6 0.47 1.75 2.63
72 INT69007 Binding of Cebpb 10 0.48 2.21 2.6
73 INT118518 Positive_regulation of Slc8a1 7 0.56 5.31 2.59
74 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58
75 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
76 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
77 INT327227 Gene_expression of Ttpa 1 0.08 12.08 2.52
78 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
79 INT103917 Positive_regulation of Phosphorylation of Egfr 12 0.68 7.23 2.18
80 INT181396 Transcription of Csf2 15 0.48 6.38 2.17
81 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
82 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
83 INT103608 Negative_regulation of Binding of Sp1 4 0.35 0.69 2.1
84 INT213788 Gene_expression of Tfeb 18 0.66 7.9 2.07
85 INT82557 Positive_regulation of Localization of Csf2 6 0.41 1.11 2.07
86 INT41495 Regulation of Sp1 7 0.42 2.96 2.05
87 INT41557 Gene_expression of Sp1 5 0.68 1.17 2.04
88 INT96881 Gene_expression of ARNT 8 0.50 3.27 1.98
89 INT160634 Gene_expression of Slc8a1 2 0.64 2.12 1.92
90 INT70538 Regulation of Localization of CSF2 4 0.54 3.08 1.9
91 INT65545 Localization of EGFR 35 0.79 20.8 1.88
92 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85
93 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82
94 INT25835 Binding of Slc8a1 3 0.36 0.47 1.79
95 INT151273 Negative_regulation of Localization of Csf2 2 0.18 0 1.79
96 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77
97 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
98 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7
99 INT81928 Positive_regulation of Binding of HSF1 4 0.49 3.04 1.67
100 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
101 INT163613 Transcription of CSF2 16 0.60 12.98 1.62
102 INT25384 Positive_regulation of Localization of Csf2 11 0.66 7.81 1.62
103 INT159489 Positive_regulation of Positive_regulation of Csf2 6 0.42 6.02 1.61
104 INT73355 Negative_regulation of Slc8a1 5 0.47 2.35 1.61
105 INT183761 Phosphorylation of Csf2 6 0.80 4.04 1.58
106 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
107 INT41605 Positive_regulation of Localization of Sp1 1 0.05 0 1.58
108 INT231917 Gene_expression of Cebpb 10 0.25 4.45 1.56
109 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54
110 INT82122 Positive_regulation of CEBPB 3 0.67 0.51 1.54
111 INT81926 Binding of HSF1 10 0.47 5.05 1.53
112 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
113 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
114 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
115 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
116 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
117 INT136459 Gene_expression of Sp3 6 0.64 1.97 1.47
118 INT46722 Regulation of Gene_expression of Csf2 8 0.45 4.84 1.45
119 INT75933 Positive_regulation of Binding of Csf2 4 0.49 2.7 1.42
120 INT194912 Regulation of Binding of Csf2 3 0.10 3.03 1.41
121 INT123414 Transcription of Sp1 5 0.48 2.2 1.38
122 INT96993 Positive_regulation of Phosphorylation of EGFR 15 0.59 5.44 1.37
123 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
124 INT213772 Positive_regulation of Tfeb 1 0.39 3.5 1.35
125 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
126 INT71304 Binding of CEBPB 3 0.36 2.69 1.32
127 INT127725 Negative_regulation of Positive_regulation of EGFR 6 0.57 2.69 1.3
128 INT67006 Positive_regulation of TTPA 5 0.49 2.31 1.29
129 INT94692 Positive_regulation of Gene_expression of Sp1 3 0.17 0.39 1.28
130 INT24000 Regulation of Sp1 2 0.22 1.25 1.27
131 INT18478 Protein_catabolism of CSF2 6 0.88 1.75 1.26
132 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
133 INT327244 Negative_regulation of Gene_expression of Ttpa 1 0.06 5.23 1.22
134 INT48554 Positive_regulation of SP1 12 0.49 3.64 1.2
135 INT16427 Negative_regulation of Positive_regulation of Csf2 2 0.43 1.5 1.2
136 INT92826 Gene_expression of Esrrb 3 0.75 1.58 1.18
137 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
138 INT327285 Phosphorylation of Ttpa 1 0.09 4.72 1.15
139 INT93216 Negative_regulation of Phosphorylation of Sp1 2 0.14 0.4 1.13
140 INT60720 Localization of Esrrb 6 0.70 0.61 1.1
141 INT118293 Regulation of Phosphorylation of EGFR 2 0.61 1.01 1.1
142 INT81921 Gene_expression of HSF1 17 0.76 9.19 1.08
143 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
144 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
145 INT80500 Localization of Slc8a1 4 0.61 1.37 1.02
146 INT86384 Negative_regulation of Localization of EGFR 4 0.43 2.5 0.97
147 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96
148 INT123408 Positive_regulation of Gene_expression of Sp1 2 0.62 0.9 0.96
149 INT62195 Positive_regulation of Hsf1 17 0.70 11.51 0.95
150 INT123407 Negative_regulation of Binding of Sp1 6 0.47 0.72 0.93
151 INT136458 Negative_regulation of Sp3 3 0.39 1.53 0.93
152 INT200272 Localization of Sp1 3 0.57 0.06 0.93
153 INT81930 Positive_regulation of Gene_expression of HSF1 4 0.66 4.07 0.88
154 INT39269 Positive_regulation of Negative_regulation of CSF2 3 0.28 1.28 0.88
155 INT47490 Regulation of Positive_regulation of CSF2 2 0.39 1.42 0.88
156 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
157 INT129678 Gene_expression of Hsf1 13 0.78 8.57 0.85
158 INT117347 Positive_regulation of Positive_regulation of EGFR 15 0.69 11.17 0.84
159 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
160 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
161 INT123410 Negative_regulation of Gene_expression of Sp1 3 0.38 1.01 0.82
162 INT171361 Regulation of Egfr 16 0.62 8.36 0.81
163 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
164 INT155052 Regulation of Gene_expression of Csf2 6 0.37 7.75 0.8
165 INT142016 Negative_regulation of Gene_expression of CEBPA 1 0.41 0.67 0.8
166 INT142018 Gene_expression of CEBPA 1 0.75 0.66 0.8
167 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
168 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
169 INT131286 Binding of Egfr 26 0.44 13.58 0.78
170 INT138955 Transcription of EGFR 18 0.71 11.39 0.78
171 INT80122 Gene_expression of ESRRB 4 0.41 2.21 0.78
172 INT181415 Regulation of Regulation of Csf2 1 0.07 2.42 0.77
173 INT186119 Protein_catabolism of EGFR 6 0.98 3.68 0.76
174 INT88814 Gene_expression of TTPA 5 0.14 2.35 0.76
175 INT56703 Negative_regulation of Negative_regulation of Csf2 1 0.38 0 0.76
176 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
177 INT232588 Negative_regulation of Binding of Csf2 4 0.38 1.47 0.74
178 INT81923 Negative_regulation of Gene_expression of HSF1 2 0.42 1.17 0.73
179 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
180 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72
181 INT68281 Positive_regulation of Positive_regulation of Csf2 5 0.67 2.17 0.72
182 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
183 INT3522 Positive_regulation of Binding of Csf2 3 0.40 0 0.71
184 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
185 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7
186 INT327246 Binding of Ttpa 1 0.05 2.48 0.7
187 INT186117 Negative_regulation of Protein_catabolism of EGFR 1 0.42 0.67 0.68
188 INT186118 Positive_regulation of Protein_catabolism of EGFR 1 0.68 0.66 0.68
189 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
190 INT187071 Localization of ESRRB 2 0.04 0.9 0.67
191 INT98967 Localization of SP1 2 0.60 0.15 0.66
192 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
193 INT24905 Negative_regulation of Gene_expression of SP1 4 0.39 2.05 0.65
194 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
195 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
196 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
197 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
198 INT187077 Positive_regulation of Localization of ESRRB 1 0.03 0.74 0.63
199 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
200 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
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