GO:0001922

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Name B-1 B cell homeostasis
Categary Process
Go Slim No
Go Link GO:0001922
Unique Molecular Interactions 94
Total Molecular Interactions 108
Total Single Events 1258
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for B-1 B cell homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for B-1 B cell homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
2 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
3 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
4 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
5 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
6 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
7 INT118919 Binding of FRTS and Sh2b2 1 0.24 0 0.39
8 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
9 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
10 INT213798 Sh2b2 Regulation of tf 1 0.12 0.53 0.27
11 INT213799 Sh2b2 Regulation of Tfeb 1 0.26 0.54 0.27
12 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
13 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
14 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
15 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
16 INT213812 Sh2b2 Positive_regulation of Tfeb 1 0.44 0.45 0.2
17 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
18 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
19 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
20 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
21 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
22 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
23 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
24 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
25 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
26 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
27 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
28 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
29 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12
30 INT207112 Sh2b2 Positive_regulation of Phosphorylation of Akt2 1 0.68 0.24 0.12
31 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12
32 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
33 INT207115 Sh2b2 Positive_regulation of Akt2 1 0.49 0.24 0.12
34 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
35 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
36 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11
37 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
38 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1
39 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
40 INT102245 TNF Positive_regulation of Binding of HIF1A 1 0.18 1.09 0.1
41 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
42 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
43 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1
44 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
45 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09
46 INT173062 Binding of HIF1A and VHLL 1 0.04 1.26 0.09
47 INT173057 Positive_regulation of HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.24 1.49 0.08
48 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
49 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
50 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 0.00 1 0.08
51 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
52 INT178103 Binding of DBP and HIF1A 1 0.00 0.99 0.07
53 INT247578 Hif1a Regulation of VEGFA 1 0.02 1.59 0.07
54 INT308328 Hif1a Regulation of Positive_regulation of Trib3 1 0.02 0.89 0.05
55 INT304322 Hif1a Positive_regulation of Positive_regulation of VEGFA 1 0.11 0.39 0.05
56 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
57 INT249921 Binding of Hif1a and Asph 1 0.05 0.41 0.04
58 INT102247 Binding of EPO and HIF1A 1 0.41 0.65 0.04
59 INT173060 Negative_regulation of VHLL Positive_regulation of Positive_regulation of HIF1A 1 0.04 0.66 0.04
60 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04
61 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
62 INT197296 Ahr Regulation of Bhlha15 1 0.48 0.47 0.03
63 INT297159 Gsta3 Negative_regulation of Hif1a 1 0.00 0.54 0.03
64 INT322471 Hif1a Positive_regulation of VEGFA 1 0.05 0.26 0.03
65 INT247576 Binding of Hif1a and Vbp1 1 0.01 0.6 0
66 INT189554 Binding of HIF1A and Positive_regulation of EGLN1 1 0.04 0.86 0
67 INT135174 Myst2 Positive_regulation of Binding of Hif1a 1 0.41 0 0
68 INT143438 HIF1A Regulation of Gene_expression of VEGFA 1 0.69 0.13 0
69 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0
70 INT247574 Ube2e3 Positive_regulation of Hif1a 1 0.04 0.62 0
71 INT241307 Positive_regulation of HIF1A Positive_regulation of Positive_regulation of EPO 1 0.12 0.64 0
72 INT247575 Binding of Epo and Hif1a 1 0.09 1.24 0
73 INT290478 Mitf Positive_regulation of HIF1A 1 0.57 0.61 0
74 INT135175 Myst2 Positive_regulation of Hif1a 1 0.41 0 0
75 INT189552 EGLN1 Positive_regulation of HIF1A 1 0.05 0.98 0
76 INT260496 Hif1a Regulation of Gene_expression of VEGFA 1 0.12 0.93 0
77 INT189127 Mch Positive_regulation of Ahr 1 0.18 0.29 0
78 INT249924 Cpox Positive_regulation of Hif1a 1 0.01 0.68 0
79 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
80 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
81 INT337352 Binding of ARNT and HIF1A 1 0.14 0.61 0
82 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0
83 INT262710 Binding of Crem and Hif1a 1 0.00 1.85 0
84 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0
85 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
86 INT143439 Positive_regulation of HIF1A Regulation of Gene_expression of VEGFA 1 0.30 0.13 0
87 INT290479 Binding of HIF1A and Mitf 1 0.30 1.29 0
88 INT119044 HIF1A Regulation of TCEAL1 1 0.02 1.06 0
89 INT313884 XRCC1 Positive_regulation of Localization of HIF1A 1 0.00 0.65 0
90 INT119047 HIF1A Regulation of Regulation of TCEAL1 1 0.08 1.06 0
91 INT345487 HIF1A Positive_regulation of PMAIP1 1 0.27 1.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for B-1 B cell homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in B-1 B cell homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
2 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
3 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
4 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
5 INT43524 Positive_regulation of Sh2b2 16 0.58 2.95 5.78
6 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
7 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
8 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
9 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8
10 INT48292 Negative_regulation of Sh2b2 9 0.26 2.14 3.26
11 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
12 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
13 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
14 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
15 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
16 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
17 INT182893 Gene_expression of Sh2b2 8 0.65 1.74 2.65
18 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
19 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
20 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
21 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
22 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
23 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
24 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
25 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
26 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
27 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
28 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
29 INT45079 Binding of Ahr 21 0.44 10.07 1
30 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
31 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
32 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
33 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
34 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
35 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
36 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
37 INT284739 Positive_regulation of Gene_expression of Sh2b2 2 0.26 0.83 0.71
38 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
39 INT182036 Gene_expression of Sh2b2 2 0.13 1.74 0.67
40 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
41 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
42 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
43 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
44 INT263996 Transcription of TNFAIP3 1 0.39 0.99 0.64
45 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
46 INT3501 Localization of Sh2b2 6 0.73 0.88 0.62
47 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
48 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
49 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
50 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
51 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
52 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
53 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
54 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
55 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
56 INT197880 Binding of Sh2b2 2 0.19 0 0.38
57 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
58 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
59 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
60 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
61 INT243808 Positive_regulation of Transcription of Sh2b2 1 0.29 0.86 0.33
62 INT243807 Transcription of Sh2b2 1 0.39 0.85 0.33
63 INT247563 Negative_regulation of Positive_regulation of Hif1a 1 0.16 9.12 0.32
64 INT313251 Negative_regulation of Positive_regulation of Sh2b2 1 0.12 0 0.29
65 INT173105 Transcription of HIF1A 6 0.67 4.47 0.28
66 INT232786 Positive_regulation of Localization of Hif1a 2 0.31 2.63 0.27
67 INT284738 Positive_regulation of Localization of Sh2b2 1 0.09 0.6 0.26
68 INT173103 Positive_regulation of Transcription of HIF1A 3 0.49 2.11 0.21
69 INT199771 Localization of Ahr 8 0.70 4.86 0.2
70 INT247564 Positive_regulation of Transcription of Hif1a 1 0.19 2.05 0.2
71 INT249919 Regulation of Regulation of Hif1a 2 0.29 1.81 0.14
72 INT249908 Binding of Hif1a 2 0.31 1.48 0.14
73 INT294583 Negative_regulation of Gene_expression of Ahr 2 0.38 1.01 0.14
74 INT249913 Regulation of Gene_expression of Hif1a 2 0.32 1.82 0.13
75 INT197287 Regulation of Gene_expression of Ahr 5 0.45 1 0.11
76 INT105392 Positive_regulation of Binding of HIF1A 5 0.45 3.83 0.1
77 INT153064 Positive_regulation of Regulation of Hif1a 1 0.45 1.52 0.1
78 INT260478 Negative_regulation of Positive_regulation of Hif1a 2 0.30 1.23 0.09
79 INT260462 Negative_regulation of Binding of Hif1a 1 0.30 1.13 0.09
80 INT260451 Positive_regulation of Positive_regulation of Hif1a 1 0.36 1.01 0.08
81 INT195858 Transcription of Ahr 2 0.69 1.33 0.07
82 INT195859 Positive_regulation of Transcription of Ahr 2 0.48 0.73 0.07
83 INT199780 Positive_regulation of Localization of Ahr 2 0.45 1.03 0.07
84 INT197288 Regulation of Positive_regulation of Ahr 1 0.59 0.45 0.07
85 INT297157 Negative_regulation of Negative_regulation of Hif1a 1 0.03 0.54 0.07
86 INT247560 Negative_regulation of Negative_regulation of Hif1a 1 0.16 2.06 0.07
87 INT143444 Positive_regulation of Localization of HIF1A 3 0.45 1.26 0.06
88 INT247553 Regulation of Negative_regulation of Hif1a 1 0.17 1.36 0.06
89 INT297158 Regulation of Localization of Hif1a 1 0.03 0.32 0.06
90 INT247559 Regulation of Positive_regulation of Hif1a 2 0.23 1.64 0.05
91 INT247555 Positive_regulation of Binding of Hif1a 2 0.31 1.15 0.05
92 INT297156 Localization of Hif1a 1 0.06 0.32 0.05
93 INT322464 Regulation of Localization of Hif1a 1 0.28 0.59 0.05
94 INT155174 Regulation of Regulation of HIF1A 3 0.24 1.57 0.04
95 INT173079 Positive_regulation of Regulation of HIF1A 1 0.26 0.64 0.04
96 INT249918 Regulation of Protein_catabolism of Hif1a 1 0.29 0.4 0.04
97 INT294584 Negative_regulation of Negative_regulation of Ahr 1 0.38 0.56 0.04
98 INT249916 Protein_catabolism of Hif1a 1 0.64 0.39 0.04
99 INT105389 Negative_regulation of Binding of HIF1A 4 0.42 3.2 0.03
100 INT217333 Positive_regulation of TNFAIP3 3 0.23 2.65 0
101 INT189607 Regulation of Binding of HIF1A 2 0.06 1.49 0
102 INT268145 Negative_regulation of Sh2b2 1 0.41 0.07 0
103 INT268165 Binding of Sh2b2 1 0.36 0.13 0
104 INT348456 Protein_catabolism of TNFAIP3 1 0.22 1.13 0
105 INT348453 Positive_regulation of Positive_regulation of TNFAIP3 1 0.17 1.06 0
106 INT189594 Negative_regulation of Transcription of HIF1A 1 0.05 0.94 0
107 INT249915 Regulation of Positive_regulation of Hif1a 1 0.29 0.85 0
108 INT112706 Negative_regulation of Gene_expression of Hif1a 1 0.08 0 0
109 INT322450 Negative_regulation of Binding of Hif1a 1 0.26 0.32 0
110 INT189606 Regulation of Transcription of HIF1A 1 0.06 0.46 0
111 INT117327 Negative_regulation of Negative_regulation of Sh2b2 1 0.25 0.13 0
112 INT249917 Regulation of Negative_regulation of Hif1a 1 0.29 0.29 0
113 INT117326 Positive_regulation of Negative_regulation of Sh2b2 1 0.27 0.16 0
114 INT247562 Negative_regulation of Transcription of Hif1a 1 0.16 2.39 0
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