GO:0001932

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Name regulation of protein phosphorylation
Categary Process
Go Slim No
Go Link GO:0001932
Unique Molecular Interactions 888
Total Molecular Interactions 1255
Total Single Events 10270
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
3 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
4 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
5 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
6 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
7 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
8 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
9 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
10 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
11 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
12 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
13 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
14 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
15 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
16 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
17 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
18 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
19 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
20 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
21 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
22 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
23 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
24 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
25 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
26 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
27 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
28 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
29 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
30 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
31 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
32 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
33 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
34 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
35 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
36 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
37 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
38 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
39 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
40 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
41 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23
42 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
43 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
44 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
45 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
46 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
47 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
48 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
49 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
50 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
51 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
52 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
53 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
54 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
55 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
56 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
57 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
58 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
59 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
60 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
61 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
62 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
63 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
64 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
65 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
66 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
67 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
68 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
69 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
70 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
71 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
72 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
73 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
74 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
75 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
76 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
77 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
78 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
79 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
80 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
81 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
82 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
83 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
84 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
85 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
86 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
87 INT168456 Arr3 Positive_regulation of Nos2 1 0.21 1.98 0.79
88 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
89 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
90 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
91 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77
92 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
93 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
94 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
95 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
96 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
97 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
98 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
99 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
100 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
101 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
102 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
103 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
104 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
105 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
106 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
107 INT354249 Binding of Mtap6 and Ppp1r9b 1 0.24 0.07 0.67
108 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
109 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
110 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
111 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
112 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
113 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
114 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
115 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
116 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
117 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
118 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63
119 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
120 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
121 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
122 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
123 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
124 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
125 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
126 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
127 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
128 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
129 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
130 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
131 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
132 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
133 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
134 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
135 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
136 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
137 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
138 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
139 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
140 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
141 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
142 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
143 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
144 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
145 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
146 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
147 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
148 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
149 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
150 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
151 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
152 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54
153 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
154 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54
155 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53
156 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
157 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
158 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53
159 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
160 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
161 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
162 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
163 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
164 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
165 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
166 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
167 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
168 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
169 INT184105 Il6 Positive_regulation of Socs3 2 0.42 1.34 0.48
170 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48
171 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
172 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48
173 INT67440 Pdyn Regulation of Gene_expression of Tnf 1 0.23 0.19 0.48
174 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
175 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
176 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48
177 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
178 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
179 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46
180 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
181 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46
182 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46
183 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45
184 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
185 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
186 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
187 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
188 INT148635 Abat Negative_regulation of Gene_expression of Tnf 1 0.10 0.53 0.44
189 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44
190 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
191 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
192 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43
193 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43
194 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43
195 INT107694 Tnf Positive_regulation of Gene_expression of Cxcl1 1 0.60 0.63 0.43
196 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
197 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43
198 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43
199 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
200 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
2 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
3 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
4 INT10166 Localization of Tnf 237 0.81 153.95 88.64
5 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
6 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
7 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
8 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
9 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
10 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
11 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
12 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
13 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
14 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
15 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
16 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
17 INT35406 Localization of Tnf 94 0.81 64.63 31.65
18 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
19 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
20 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
21 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
22 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
23 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
24 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
25 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
26 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
27 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
28 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
29 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
30 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
31 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
32 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
33 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
34 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34
35 INT75908 Regulation of LEP 77 0.60 60.16 15.19
36 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
37 INT10173 Binding of Tnf 45 0.48 35.6 14.32
38 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
39 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
40 INT73641 Regulation of Lep 45 0.62 26.2 12.59
41 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
42 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
43 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
44 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
45 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
46 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
47 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
48 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
49 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
50 INT34777 Localization of IGF1 82 0.80 42.68 8.62
51 INT82082 Localization of Lep 63 0.81 26.41 8.56
52 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
53 INT75907 Binding of LEP 53 0.46 46.65 8.44
54 INT142462 Positive_regulation of Gene_expression of Socs3 23 0.68 23.27 8.27
55 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
56 INT68299 Binding of Tnf 17 0.39 12.55 7.49
57 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
58 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
59 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
60 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
61 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
62 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
63 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
64 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
65 INT53871 Gene_expression of Socs1 32 0.71 22.83 6.21
66 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
67 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
68 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
69 INT151032 Localization of Igf1 49 0.76 26.32 5.71
70 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
71 INT42378 Positive_regulation of Socs3 21 0.67 15.81 5.71
72 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
73 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
74 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
75 INT65356 Localization of LEP 46 0.79 41.17 5.43
76 INT91338 Binding of Lep 31 0.48 26.86 5.39
77 INT102935 Regulation of Lep 31 0.60 18.47 5.24
78 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
79 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
80 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
81 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
82 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
83 INT97391 Binding of Lep 18 0.48 8.97 4.47
84 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
85 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
86 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
87 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
88 INT49360 Localization of Igf1 22 0.76 6.96 4.26
89 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
90 INT163581 Localization of Lep 27 0.79 18.99 4.08
91 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
92 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
93 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
94 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
95 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
96 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
97 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
98 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
99 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
100 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
101 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
102 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
103 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
104 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
105 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
106 INT16130 Binding of IGF1 67 0.48 27.43 2.95
107 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
108 INT184005 Negative_regulation of Gene_expression of Socs3 6 0.48 8.76 2.74
109 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
110 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
111 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
112 INT142465 Negative_regulation of Socs3 8 0.48 8.31 2.62
113 INT169798 Positive_regulation of Rapgef3 1 0.45 1.7 2.56
114 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
115 INT66544 Binding of Igf1 23 0.46 8.33 2.44
116 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
117 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
118 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
119 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
120 INT184054 Negative_regulation of Gene_expression of Socs1 7 0.53 9.18 2.22
121 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
122 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
123 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08
124 INT83392 Transcription of Lep 6 0.54 5.07 2.04
125 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
126 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
127 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
128 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
129 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
130 INT184042 Negative_regulation of Socs1 9 0.46 8.1 1.88
131 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
132 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
133 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
134 INT184068 Positive_regulation of Socs1 7 0.51 4.03 1.73
135 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
136 INT254250 Regulation of Socs1 5 0.06 3.04 1.66
137 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
138 INT97062 Binding of PML 10 0.41 11.63 1.65
139 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
140 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
141 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
142 INT184052 Localization of Socs1 3 0.59 4.07 1.54
143 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
144 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
145 INT184032 Regulation of Socs3 6 0.37 4.08 1.48
146 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
147 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
148 INT169799 Binding of Rapgef3 1 0.30 1.04 1.43
149 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
150 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
151 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
152 INT9888 Gene_expression of Arr3 2 0.51 3.34 1.38
153 INT144805 Regulation of Negative_regulation of Ppp2ca 1 0.28 0.24 1.38
154 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
155 INT90491 Binding of Igf1 25 0.44 9.75 1.36
156 INT184056 Regulation of Gene_expression of Socs3 4 0.45 4.24 1.22
157 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
158 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
159 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
160 INT196785 Regulation of Ppp2ca 5 0.54 2.1 1.17
161 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
162 INT213465 Transcription of Lep 4 0.68 2.11 1.15
163 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
164 INT179884 Gene_expression of SOCS3 10 0.67 16.57 1.14
165 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
166 INT354243 Negative_regulation of Ppp1r9b 1 0.28 0.28 1.12
167 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
168 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
169 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
170 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
171 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
172 INT184020 Localization of Socs3 3 0.75 4.05 1.06
173 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
174 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
175 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
176 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
177 INT90278 Localization of Ppp2ca 4 0.66 1.12 0.94
178 INT196754 Binding of Ppp2ca 5 0.37 0.42 0.89
179 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
180 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
181 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
182 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
183 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
184 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
185 INT184014 Binding of Socs1 2 0.34 0.97 0.84
186 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
187 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
188 INT184026 Binding of Socs3 7 0.42 1.93 0.81
189 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
190 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
191 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
192 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
193 INT156533 Transcription of LEP 9 0.69 4.35 0.74
194 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
195 INT254249 Transcription of Socs1 2 0.29 1.6 0.74
196 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
197 INT262726 Localization of PML 6 0.57 7.13 0.72
198 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7
199 INT196742 Positive_regulation of Positive_regulation of Ppp2ca 4 0.44 0.05 0.68
200 INT218815 Localization of Ppp1r9b 1 0.47 1.2 0.65
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