GO:0001933

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Name negative regulation of protein phosphorylation
Categary Process
Go Slim No
Go Link GO:0001933
Unique Molecular Interactions 896
Total Molecular Interactions 1148
Total Single Events 10811
Pain Genes Associated 52

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
2 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
3 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
4 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
5 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
6 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
7 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
8 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
9 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
10 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96
11 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
12 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
13 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
14 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
15 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
16 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
17 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
18 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
19 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
20 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
21 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
22 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
23 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
24 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
25 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
26 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
27 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
28 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
29 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
30 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
31 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
32 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3
33 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
34 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
35 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
36 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
37 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
38 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
39 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
40 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
41 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16
42 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
43 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
44 INT88614 Penk Negative_regulation of Il2 1 0.23 0 1.08
45 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
46 INT54501 beta-End6-31 Positive_regulation of Gene_expression of Il2 1 0.03 0 1.06
47 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 0.00 0.27 1
48 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
49 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
50 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
51 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
52 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
53 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
54 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
55 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
56 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
57 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
58 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
59 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
60 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
61 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
62 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
63 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
64 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
65 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
66 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
67 INT161306 POMC Negative_regulation of Transcription of IL2 1 0.24 0.27 0.85
68 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
69 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
70 INT127240 Bdkrb1 Regulation of Ssr1 1 0.01 0.08 0.84
71 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
72 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
73 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
74 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
75 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
76 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
77 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
78 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
79 INT12883 Binding of IL2 and POMC 1 0.01 0 0.81
80 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
81 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
82 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
83 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
84 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
85 INT8411 IL2 Regulation of Gene_expression of Vip 1 0.00 0.27 0.8
86 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
87 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
88 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
89 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
90 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
91 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
92 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
93 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
94 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
95 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
96 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
97 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
98 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
99 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
100 INT21535 Binding of Il2 and Il1f5 1 0.13 0 0.73
101 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
102 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73
103 INT209053 Il2 Positive_regulation of Elf1 1 0.06 0.38 0.73
104 INT209036 Il2 Positive_regulation of Cxcl1 1 0.04 0.38 0.73
105 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73
106 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72
107 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72
108 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
109 INT317586 Binding of SCLY and Ppap2b 1 0.00 0.78 0.72
110 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
111 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72
112 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
113 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
114 INT27034 HERPUD1 Regulation of Gene_expression of IL2 1 0.38 0 0.71
115 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
116 INT151681 Il2 Negative_regulation of Art2a-ps 1 0.00 1.23 0.7
117 INT151678 Il2 Negative_regulation of Oas1b 1 0.13 1.23 0.7
118 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
119 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
120 INT54502 Pomc Positive_regulation of Gene_expression of Il2 1 0.16 0 0.68
121 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68
122 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
123 INT169217 Binding of Pebp1 and Coc 1 0.00 0.22 0.67
124 INT56308 POMC Negative_regulation of Gene_expression of Il2 1 0.01 0.1 0.67
125 INT274871 Positive_regulation of Cbr2 Positive_regulation of Positive_regulation of Dusp6 1 0.02 0.72 0.67
126 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
127 INT82382 Penk Positive_regulation of Gene_expression of Il2 1 0.10 0 0.66
128 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
129 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
130 INT72504 IgG Negative_regulation of Il2 1 0.37 0 0.65
131 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
132 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
133 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
134 INT86171 Oprl1 Positive_regulation of Gene_expression of Il2 1 0.30 0 0.64
135 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
136 INT65256 Pebp1 Regulation of Gene_expression of Basp1 1 0.00 0.05 0.64
137 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
138 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
139 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
140 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6
141 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
142 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
143 INT13238 POMC Regulation of Gene_expression of IL2 1 0.09 0.26 0.59
144 INT60375 Il2 Regulation of Localization of Penk 1 0.03 0 0.59
145 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
146 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58
147 INT120349 Binding of BDKRB1 and DES 1 0.05 0.17 0.58
148 INT60374 Il2 Positive_regulation of Pomc 1 0.07 0 0.58
149 INT60372 Il2 Positive_regulation of Localization of Pomc 1 0.08 0 0.58
150 INT60373 Il2 Positive_regulation of Localization of Penk 1 0.52 0 0.58
151 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
152 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
153 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
154 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
155 INT144598 Hrh2 Positive_regulation of IL2 1 0.01 0.08 0.56
156 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
157 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
158 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
159 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
160 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
161 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
162 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53
163 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
164 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
165 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52
166 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
167 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
168 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
169 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
170 INT303720 Prkaca Regulation of Bdkrb1 1 0.02 0.33 0.52
171 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
172 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
173 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
174 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
175 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
176 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
177 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
178 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
179 INT32597 Pomc Regulation of Gene_expression of Il2 1 0.29 0 0.49
180 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
181 INT254638 Bdkrb2 Positive_regulation of Positive_regulation of Bdkrb1 1 0.09 0.96 0.48
182 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47
183 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
184 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
185 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
186 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
187 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46
188 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
189 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
190 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46
191 INT242401 Negative_regulation of Bdkrb1 Negative_regulation of Gene_expression of Mcpt1 1 0.16 1.45 0.46
192 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46
193 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
194 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45
195 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
196 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
197 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
198 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
199 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
200 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
2 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
3 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
4 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
5 INT11807 Gene_expression of Il2 266 0.78 112 64.97
6 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
7 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
8 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
9 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
10 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
11 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
12 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
13 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21
14 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
15 INT10763 Localization of IL2 157 0.80 81.11 33.21
16 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
17 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
18 INT8691 Localization of Insr 85 0.80 9.27 30.32
19 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
20 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
21 INT5300 Regulation of Insr 54 0.60 11.33 29.26
22 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
23 INT28834 Positive_regulation of Bdkrb1 38 0.69 30.48 26.89
24 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
25 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
26 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
27 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
28 INT117527 Binding of Prkca 25 0.48 6.43 21.05
29 INT15796 Regulation of IL2 66 0.61 25.43 20.62
30 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
31 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
32 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96
33 INT30517 Negative_regulation of Bdkrb1 16 0.58 16.52 16.88
34 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2
35 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1
36 INT59987 Gene_expression of BDKRB1 25 0.77 11.95 15.93
37 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
38 INT78827 Gene_expression of Bdkrb1 34 0.78 18.48 15.81
39 INT79458 Localization of Prkca 30 0.81 11.13 15.78
40 INT61301 Positive_regulation of Gene_expression of Bdkrb1 7 0.68 16.95 15.44
41 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
42 INT22098 Positive_regulation of Il2 27 0.69 14.77 14.1
43 INT6645 Positive_regulation of BDKRB1 14 0.66 12.17 13.79
44 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
45 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
46 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34
47 INT20381 Localization of Il2 71 0.77 34.23 13.03
48 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
49 INT51014 Transcription of IL2 42 0.71 21.56 12.7
50 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56
51 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
52 INT14334 Negative_regulation of Il2 31 0.58 18.63 11.08
53 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
54 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
55 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23
56 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
57 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
58 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
59 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
60 INT7104 Binding of Bdkrb1 6 0.37 6.54 9.02
61 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
62 INT22383 Binding of IL2 59 0.48 39.06 8.56
63 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
64 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19
65 INT113038 Positive_regulation of Gene_expression of Bdkrb1 12 0.69 7.11 7.93
66 INT32596 Regulation of Gene_expression of Il2 13 0.61 6.85 7.83
67 INT62452 Regulation of Il2 14 0.61 12.11 7.64
68 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
69 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
70 INT3928 Localization of Bdkrb1 15 0.75 4.06 7.23
71 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22
72 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
73 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
74 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
75 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
76 INT98260 Negative_regulation of Gene_expression of Bdkrb1 4 0.57 5.98 6.7
77 INT70139 Regulation of Bdkrb1 6 0.52 8.41 6.66
78 INT33781 Binding of Pebp1 11 0.44 1.76 6.61
79 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54
80 INT25385 Positive_regulation of Localization of Il2 17 0.45 9.53 6.45
81 INT1280 Negative_regulation of Pebp1 7 0.28 2.12 6.45
82 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
83 INT52464 Negative_regulation of Bdkrb1 9 0.57 8.71 5.87
84 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
85 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
86 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
87 INT12066 Localization of Il2 16 0.75 3.06 5.7
88 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
89 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
90 INT69572 Localization of Prnp 96 0.81 38.11 5.45
91 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
92 INT11805 Regulation of Gene_expression of Il2 19 0.62 6.62 5.2
93 INT125396 Positive_regulation of Positive_regulation of Bdkrb1 5 0.69 5.14 5.2
94 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
95 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
96 INT59983 Regulation of BDKRB1 12 0.45 10.69 5.11
97 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
98 INT59320 Transcription of Il2 32 0.69 6.39 4.95
99 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
100 INT58459 Negative_regulation of Localization of IL2 13 0.41 6.46 4.88
101 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
102 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
103 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
104 INT113037 Transcription of Bdkrb1 4 0.69 3.89 4.82
105 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81
106 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78
107 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
108 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
109 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
110 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
111 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
112 INT113039 Binding of Bdkrb1 9 0.48 5.71 4.51
113 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
114 INT69570 Binding of Prnp 75 0.48 44.26 4.37
115 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
116 INT103037 Transcription of Bdkrb1 8 0.70 4.76 4.33
117 INT51084 Binding of Insr 13 0.30 4.25 4.23
118 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
119 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
120 INT83035 Binding of INSR 16 0.47 9.29 4.11
121 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
122 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
123 INT29138 Positive_regulation of Localization of IL2 25 0.50 10.06 3.89
124 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
125 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
126 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
127 INT133788 Negative_regulation of Gene_expression of Bdkrb1 7 0.58 3.49 3.75
128 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
129 INT61300 Negative_regulation of Binding of Bdkrb1 3 0.42 3 3.69
130 INT76229 Binding of BDKRB1 5 0.33 1.46 3.66
131 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
132 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
133 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
134 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
135 INT10116 Localization of INSR 11 0.57 5.43 3.48
136 INT59984 Regulation of Gene_expression of BDKRB1 2 0.45 2.08 3.47
137 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
138 INT59986 Localization of BDKRB1 5 0.61 1.69 3.45
139 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
140 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
141 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
142 INT21572 Gene_expression of Pebp1 9 0.71 2.52 3.3
143 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
144 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
145 INT102255 Regulation of Prnp 35 0.62 18.97 3.25
146 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
147 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
148 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
149 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
150 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
151 INT192676 Binding of PTEN 14 0.46 10.58 3.06
152 INT123595 Regulation of Snca 7 0.62 4.3 3.06
153 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
154 INT66716 Negative_regulation of BDKRB1 4 0.48 1.31 3
155 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
156 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
157 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
158 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
159 INT11815 Regulation of Il2 16 0.59 4.81 2.83
160 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
161 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
162 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
163 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
164 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62
165 INT22831 Negative_regulation of Positive_regulation of IL2 7 0.55 1.7 2.62
166 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
167 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
168 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
169 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
170 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45
171 INT51279 Regulation of IGFBP3 17 0.49 15.89 2.45
172 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43
173 INT163544 Binding of Psen1 40 0.36 15.28 2.42
174 INT303703 Positive_regulation of Transcription of Bdkrb1 2 0.21 2.91 2.41
175 INT133789 Regulation of Gene_expression of Bdkrb1 5 0.39 3 2.38
176 INT25382 Binding of Il2 16 0.37 11.69 2.32
177 INT72531 Binding of Il2 2 0.48 0.18 2.32
178 INT28833 Localization of Bdkrb1 3 0.81 2.17 2.28
179 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
180 INT20289 Regulation of Localization of IL2 7 0.26 1.23 2.24
181 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
182 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
183 INT227153 Negative_regulation of PEBP1 1 0.12 0.51 2.17
184 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
185 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
186 INT317583 Positive_regulation of Ppap2b 1 0.09 2.14 2.09
187 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
188 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
189 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
190 INT28832 Negative_regulation of Positive_regulation of Bdkrb1 3 0.23 1.36 2.04
191 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
192 INT60723 Localization of Psen2 5 0.68 2.11 2.02
193 INT62556 Positive_regulation of Gene_expression of BDKRB1 3 0.46 0.65 1.98
194 INT149761 Negative_regulation of MAS1 5 0.29 1.91 1.95
195 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
196 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
197 INT49371 Positive_regulation of Gene_expression of IGFBP3 27 0.70 23.13 1.9
198 INT52789 Regulation of Localization of Il2 9 0.30 1.9 1.88
199 INT127125 Localization of Snca 6 0.81 8.24 1.88
200 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
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