GO:0001934

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Name positive regulation of protein phosphorylation
Categary Process
Go Slim No
Go Link GO:0001934
Unique Molecular Interactions 4695
Total Molecular Interactions 6670
Total Single Events 51876
Pain Genes Associated 168

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
3 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
4 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
5 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
6 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
7 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
8 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
9 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
10 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
11 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
12 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
13 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
14 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
15 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
16 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
17 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
18 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
19 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
20 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
21 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
22 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
23 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
24 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
25 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
26 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
27 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
28 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
29 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
30 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
31 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
32 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
33 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
34 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
35 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
36 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
37 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
38 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
39 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
40 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
41 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
42 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
43 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
44 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
45 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
46 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
47 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
48 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
49 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
50 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
51 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
52 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
53 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
54 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
55 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
56 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
57 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
58 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
59 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
60 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
61 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
62 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
63 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
64 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
65 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
66 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
67 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
68 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
69 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
70 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
71 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
72 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
73 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
74 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
75 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
76 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
77 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
78 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
79 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
80 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
81 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
82 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
83 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
84 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
85 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
86 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
87 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
88 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
89 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
90 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
91 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
92 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
93 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
94 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
95 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
96 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
97 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
98 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
99 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
100 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
101 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
102 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
103 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
104 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
105 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
106 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
107 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
108 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
109 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
110 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
111 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
112 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
113 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
114 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
115 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
116 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
117 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
118 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
119 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
120 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
121 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
122 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
123 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
124 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
125 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
126 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
127 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
128 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
129 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
130 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
131 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
132 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
133 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
134 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
135 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
136 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
137 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
138 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
139 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
140 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
141 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
142 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
143 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
144 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
145 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
146 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
147 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
148 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
149 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
150 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
151 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
152 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
153 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
154 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
155 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
156 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
157 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
158 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
159 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
160 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
161 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
162 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
163 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
164 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
165 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
166 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
167 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
168 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
169 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
170 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
171 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
172 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
173 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
174 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
175 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
176 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
177 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
178 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
179 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
180 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
181 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
182 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
183 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
184 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
185 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
186 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
187 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
188 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
189 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
190 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
191 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
192 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
193 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
194 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
195 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
196 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
197 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
198 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
199 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
200 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT1562 Localization of Crh 499 0.81 126.74 236.68
8 INT6481 Binding of TNF 624 0.48 510.2 214.82
9 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
10 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
11 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
12 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
13 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
14 INT9660 Regulation of TNF 363 0.62 312.94 139.99
15 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
16 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
17 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
18 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
19 INT1898 Regulation of Crh 220 0.62 61.33 102.64
20 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
21 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
22 INT10166 Localization of Tnf 237 0.81 153.95 88.64
23 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
24 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
25 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
26 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
27 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
28 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
29 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
30 INT6849 Localization of IL1B 229 0.81 112.56 69.63
31 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
32 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
33 INT11807 Gene_expression of Il2 266 0.78 112 64.97
34 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
35 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
36 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
37 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
38 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
39 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
40 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
41 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
42 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
43 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
44 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
45 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
46 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
47 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
48 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
49 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
50 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
51 INT13354 Transcription of TNF 108 0.72 85.81 42.32
52 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
53 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
54 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
55 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
56 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
57 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
58 INT6484 Binding of IL1B 122 0.47 75.84 35.07
59 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
60 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
61 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
62 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
63 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68
64 INT10763 Localization of IL2 157 0.80 81.11 33.21
65 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
66 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
67 INT35406 Localization of Tnf 94 0.81 64.63 31.65
68 INT9347 Localization of Il1b 58 0.81 26.13 31.53
69 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
70 INT8691 Localization of Insr 85 0.80 9.27 30.32
71 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
72 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
73 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
74 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
75 INT5300 Regulation of Insr 54 0.60 11.33 29.26
76 INT16879 Binding of Crh 72 0.48 21.65 28.43
77 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
78 INT116737 Localization of Mif 63 0.81 52.97 28.11
79 INT21379 Transcription of Crh 65 0.72 15.64 27.92
80 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
81 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
82 INT10799 Localization of ENG 63 0.78 18.67 27.28
83 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
84 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
85 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
86 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
87 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
88 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
89 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
90 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
91 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
92 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
93 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
94 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
95 INT48081 Localization of Il1b 46 0.80 21.59 22.4
96 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
97 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
98 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
99 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
100 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
101 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
102 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
103 INT117527 Binding of Prkca 25 0.48 6.43 21.05
104 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
105 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
106 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
107 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
108 INT15796 Regulation of IL2 66 0.61 25.43 20.62
109 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
110 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
111 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
112 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
113 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
114 INT8075 Localization of Crh 64 0.81 25.41 19.45
115 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
116 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
117 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
118 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
119 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
120 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
121 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
122 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
123 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
124 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96
125 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
126 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
127 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
128 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
129 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
130 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2
131 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
132 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
133 INT79458 Localization of Prkca 30 0.81 11.13 15.78
134 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
135 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
136 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
137 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
138 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
139 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66
140 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
141 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
142 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
143 INT7674 Regulation of ENG 42 0.30 11.41 14.44
144 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
145 INT10173 Binding of Tnf 45 0.48 35.6 14.32
146 INT22098 Positive_regulation of Il2 27 0.69 14.77 14.1
147 INT133156 Binding of Cd40 77 0.48 45.92 13.77
148 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
149 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
150 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
151 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
152 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
153 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
154 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
155 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
156 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
157 INT20381 Localization of Il2 71 0.77 34.23 13.03
158 INT7585 Regulation of Crh 24 0.58 9.88 12.97
159 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
160 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
161 INT51014 Transcription of IL2 42 0.71 21.56 12.7
162 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
163 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
164 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56
165 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
166 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
167 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
168 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
169 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
170 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
171 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
172 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
173 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
174 INT72949 Binding of Mif 31 0.46 23.12 11.65
175 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
176 INT14334 Negative_regulation of Il2 31 0.58 18.63 11.08
177 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
178 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
179 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
180 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
181 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
182 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
183 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
184 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23
185 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
186 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
187 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
188 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
189 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
190 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
191 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
192 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
193 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
194 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
195 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
196 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
197 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03
198 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
199 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
200 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
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