GO:0001947

From wiki-pain
Jump to: navigation, search
Name heart looping
Categary Process
Go Slim No
Go Link GO:0001947
Unique Molecular Interactions 518
Total Molecular Interactions 697
Total Single Events 4699
Pain Genes Associated 48

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for heart looping. They are ordered first by their pain relevance and then by number of times they were reported for heart looping. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
3 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
4 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
5 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
6 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
7 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
8 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
9 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
10 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
11 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
12 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
13 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
14 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
15 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
16 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
17 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
18 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
19 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
20 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98
21 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
22 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
23 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
24 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
25 INT153370 LBX1 Positive_regulation of Gene_expression of Slc6a5 1 0.02 0 0.88
26 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
27 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
28 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
29 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
30 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
31 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
32 INT32719 ENG Regulation of LH 2 0.00 0 0.64
33 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
34 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
35 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
36 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
37 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
38 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55
39 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
40 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
41 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54
42 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
43 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
44 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
45 INT32291 ENG Negative_regulation of LH 2 0.00 0 0.52
46 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
47 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
48 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5
49 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
50 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
51 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
52 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
53 INT60871 ENG Regulation of Localization of LH 1 0.00 0 0.49
54 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48
55 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
56 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
57 INT60870 ENG Negative_regulation of Localization of LH 1 0.00 0 0.47
58 INT102213 Binding of ENG and HP 1 0.01 0 0.47
59 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
60 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
61 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
62 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
63 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
64 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
65 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42
66 INT202516 Positive_regulation of Binding of ENG and Penk 1 0.03 0.58 0.42
67 INT202515 Binding of ENG and Penk 1 0.02 0.57 0.41
68 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
69 INT32720 Negative_regulation of ENG Regulation of LH 1 0.00 0 0.41
70 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
71 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
72 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
73 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
74 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
75 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
76 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
77 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33
78 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
79 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
80 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
81 INT112018 Binding of Hand1 and IgG2a 2 0.22 0.84 0.32
82 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
83 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
84 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
85 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32
86 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
87 INT112022 Binding of Hand1 and Ifng 1 0.09 0.3 0.32
88 INT241138 Ighg1 Positive_regulation of Hand1 1 0.06 0.64 0.32
89 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
90 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
91 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
92 INT188707 Binding of IFNA1 and Hand1 1 0.01 0.56 0.32
93 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
94 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
95 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
96 INT243631 Binding of Hand1 and Nfatc1 1 0.04 0.76 0.3
97 INT55404 Binding of ENG and Th 1 0.02 0 0.3
98 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
99 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
100 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
101 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
102 INT252604 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Hand1 1 0.24 0.5 0.29
103 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
104 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
105 INT29137 ENG Regulation of POMC 1 0.00 0 0.28
106 INT185076 Bpifa2 Positive_regulation of Hand2 1 0.16 0.36 0.28
107 INT278209 Ciita Regulation of Hand2 1 0.36 1.53 0.28
108 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
109 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
110 INT29139 ENG Regulation of Oprl1 1 0.00 0 0.28
111 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
112 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
113 INT278216 Ciita Regulation of Gene_expression of Hand2 1 0.36 1.53 0.28
114 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
115 INT246439 Hand1 Positive_regulation of Gene_expression of Cd79a 1 0.04 0.78 0.27
116 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 0.03 0.78 0.27
117 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
118 INT32156 Binding of ENG and Oprd1 1 0.00 0 0.26
119 INT32149 Binding of ENG and LLGL1 1 0.11 0 0.26
120 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26
121 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
122 INT294514 Safb Positive_regulation of Localization of Hand1 1 0.08 0.38 0.25
123 INT331767 Hand1 Positive_regulation of Nos2 1 0.08 0.48 0.23
124 INT43713 ENG Regulation of Prl 1 0.00 0 0.23
125 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
126 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
127 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
128 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22
129 INT333758 Hand1 Positive_regulation of Eae1 1 0.05 1.6 0.22
130 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22
131 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
132 INT163863 Binding of MIB1 and Vim 1 0.02 1.06 0.21
133 INT163864 Binding of MIB1 and Ema 1 0.04 1.07 0.21
134 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21
135 INT311987 Binding of Cd40 and Negative_regulation of Regulation of Hand1 1 0.28 0.27 0.21
136 INT276241 Slc11a1 Positive_regulation of Gene_expression of Hand1 1 0.02 1.24 0.21
137 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2
138 INT348970 Binding of MOG and HAND1 1 0.03 1.28 0.2
139 INT188698 Hand1 Positive_regulation of Localization of Mthfd1 1 0.06 0.71 0.2
140 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2
141 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 0.07 0.5 0.2
142 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
143 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2
144 INT175464 Hand2 Positive_regulation of Gene_expression of Sftpd 1 0.19 1.05 0.2
145 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
146 INT238010 Binding of Cxcr3 and Hand1 1 0.12 1.55 0.19
147 INT228737 Rae1 Negative_regulation of Hand2 1 0.08 1.07 0.19
148 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
149 INT284889 Gene_expression of Hand1 Positive_regulation of Gene_expression of Il4 1 0.21 0.4 0.18
150 INT329841 Il4 Regulation of Hand1 1 0.04 0.87 0.18
151 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
152 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
153 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18
154 INT252600 Ppig Regulation of Hand1 1 0.06 0.43 0.17
155 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17
156 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17
157 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
158 INT252598 Ppig Regulation of Gene_expression of Hand1 1 0.06 0.43 0.17
159 INT244848 Lbx1 Negative_regulation of Cdca3 1 0.07 0.09 0.17
160 INT244858 Lbx1 Negative_regulation of C6 1 0.28 0.09 0.17
161 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
162 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16
163 INT244840 Lbx1 Negative_regulation of C9 1 0.13 0.09 0.16
164 INT244843 Lbx1 Negative_regulation of Hoxd10 1 0.02 0.09 0.16
165 INT244850 Lbx1 Negative_regulation of Hoxd8 1 0.01 0.09 0.16
166 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
167 INT244844 Lbx1 Negative_regulation of Hoxd9 1 0.01 0.09 0.16
168 INT244842 Lbx1 Negative_regulation of Hoxc13 1 0.02 0.09 0.16
169 INT244845 Lbx1 Negative_regulation of Grcc10 1 0.09 0.09 0.16
170 INT244855 Lbx1 Negative_regulation of Dio1 1 0.03 0.09 0.16
171 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
172 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15
173 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
174 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
175 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
176 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
177 INT279102 Renbp Regulation of Hand1 1 0.02 0.27 0.14
178 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14
179 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14
180 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
181 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
182 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14
183 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14
184 INT294761 Binding of Hand1 and Cerk 1 0.23 0.36 0.14
185 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14
186 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13
187 INT225989 Il10 Negative_regulation of Gene_expression of Hand1 1 0.11 0.68 0.13
188 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
189 INT347019 Cd80 Regulation of Hand1 1 0.01 0.05 0.13
190 INT347007 Cd86 Regulation of Hand2 1 0.06 0.05 0.13
191 INT32294 ENG Positive_regulation of Trh 1 0.01 0 0.13
192 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
193 INT347014 Cd86 Regulation of Hand1 1 0.02 0.05 0.13
194 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
195 INT223539 Binding of HAND1 and Szf1 1 0.33 0.92 0.13
196 INT244847 Lbx1 Positive_regulation of Skor1 1 0.47 0.08 0.13
197 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
198 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
199 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
200 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for heart looping. They are ordered first by their pain relevance and then by number of times they were reported in heart looping. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
2 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
3 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
4 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
5 INT10799 Localization of ENG 63 0.78 18.67 27.28
6 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
7 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
8 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
9 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
10 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
11 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
12 INT7674 Regulation of ENG 42 0.30 11.41 14.44
13 INT173505 Localization of Hand2 63 0.57 45.32 13.66
14 INT20378 Localization of Hand1 53 0.71 41.96 13.31
15 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39
16 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88
17 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
18 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
19 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
20 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
21 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
22 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
23 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
24 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
25 INT23375 Binding of ENG 17 0.47 6.02 6.46
26 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
27 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
28 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
29 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
30 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
31 INT141275 Negative_regulation of Gene_expression of Hand1 18 0.34 15.83 5.05
32 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
33 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
34 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
35 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
36 INT151736 Binding of Hand1 15 0.26 9.77 4.04
37 INT156131 Binding of Hand2 14 0.25 10.35 3.99
38 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
39 INT15844 Positive_regulation of Localization of ENG 7 0.67 4.2 3.47
40 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
41 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
42 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
43 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
44 INT32222 Negative_regulation of Gene_expression of ENG 9 0.37 2.23 2.89
45 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
46 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
47 INT94463 Regulation of Gene_expression of Hand1 10 0.36 5.17 2.72
48 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
49 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
50 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62
51 INT163544 Binding of Psen1 40 0.36 15.28 2.42
52 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31
53 INT12133 Regulation of Localization of ENG 3 0.03 0.57 2.24
54 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
55 INT87778 Positive_regulation of Gene_expression of Gja1 6 0.69 1.46 2.14
56 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
57 INT228061 Positive_regulation of Localization of Hand1 8 0.26 6.39 2.06
58 INT112015 Negative_regulation of Regulation of Hand1 5 0.33 3.48 2.05
59 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
60 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99
61 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
62 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
63 INT87779 Positive_regulation of Gja1 4 0.53 0.9 1.95
64 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
65 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
66 INT87776 Positive_regulation of Phosphorylation of Gja1 3 0.62 0.71 1.86
67 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
68 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
69 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
70 INT15845 Negative_regulation of Localization of ENG 3 0.05 0.76 1.71
71 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
72 INT285510 Regulation of Localization of Hand1 6 0.14 6.13 1.61
73 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
74 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
75 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
76 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
77 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
78 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
79 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
80 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
81 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
82 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
83 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
84 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
85 INT32717 Negative_regulation of Regulation of ENG 3 0.00 0.43 1.25
86 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24
87 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
88 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
89 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
90 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
91 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
92 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
93 INT51863 Negative_regulation of Negative_regulation of ENG 2 0.04 0.51 1.13
94 INT237456 Gene_expression of MESP1 1 0.03 1.33 1.12
95 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
96 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
97 INT237904 Negative_regulation of Localization of Hand1 5 0.24 3.52 1.09
98 INT325047 Gene_expression of Hand1 1 0.07 6.42 1.06
99 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
100 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
101 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
102 INT67097 Gene_expression of MIB1 20 0.75 21.06 1.03
103 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
104 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
105 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
106 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
107 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
108 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
109 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
110 INT134822 Gene_expression of Gja1 18 0.72 4.2 1
111 INT235516 Positive_regulation of Localization of Hand2 4 0.36 3.04 0.97
112 INT226419 Negative_regulation of Localization of Hand2 4 0.30 3.17 0.96
113 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
114 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
115 INT26531 Regulation of Srf 3 0.18 0.62 0.9
116 INT153360 Positive_regulation of LBX1 1 0.20 0 0.88
117 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
118 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86
119 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
120 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
121 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
122 INT103362 Gene_expression of Lbx1 3 0.78 0.14 0.81
123 INT87777 Regulation of Gja1 1 0.62 0.76 0.81
124 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
125 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
126 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
127 INT270447 Binding of Smo 2 0.07 2.61 0.78
128 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
129 INT45293 Transcription of Srf 2 0.47 0.79 0.76
130 INT143306 Positive_regulation of Gja1 3 0.50 0.42 0.75
131 INT128402 Negative_regulation of Phosphorylation of Gja1 1 0.58 0.73 0.73
132 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
133 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
134 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
135 INT185049 Transcription of Hand1 5 0.47 1.84 0.71
136 INT152909 Regulation of Gene_expression of Gja1 1 0.61 0.46 0.69
137 INT174517 Localization of AHI1 2 0.24 1.62 0.68
138 INT95337 Negative_regulation of AHI1 2 0.02 0.75 0.68
139 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
140 INT271488 Negative_regulation of Negative_regulation of Hand2 3 0.18 2.36 0.67
141 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
142 INT87781 Regulation of Phosphorylation of Gja1 1 0.27 0 0.67
143 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
144 INT80025 Positive_regulation of MIB1 5 0.40 5.41 0.64
145 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
146 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
147 INT11763 Positive_regulation of Regulation of ENG 1 0.01 0.97 0.64
148 INT231131 Regulation of HAND1 5 0.27 1.81 0.63
149 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
150 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
151 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
152 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
153 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
154 INT181529 Regulation of Positive_regulation of Hand1 2 0.16 2.62 0.61
155 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
156 INT113042 Localization of IHH 1 0.70 0.77 0.61
157 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
158 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
159 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
160 INT132588 Positive_regulation of Negative_regulation of Hand2 1 0.03 0.47 0.58
161 INT325055 Binding of Hand1 1 0.04 2.15 0.58
162 INT90939 Positive_regulation of Eng 9 0.64 4.62 0.57
163 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
164 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
165 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
166 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
167 INT154837 Regulation of Gja1 2 0.45 1.42 0.53
168 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
169 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
170 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
171 INT279099 Regulation of Regulation of Hand1 3 0.20 1.31 0.5
172 INT154268 Gene_expression of LBX1 2 0.12 0.27 0.5
173 INT134820 Positive_regulation of Gene_expression of Gja1 3 0.64 0.84 0.49
174 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
175 INT87774 Binding of Gja1 2 0.48 0.19 0.48
176 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
177 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
178 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
179 INT206484 Localization of Shh 2 0.75 1.14 0.46
180 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
181 INT231129 Positive_regulation of HAND1 5 0.30 2.73 0.45
182 INT103360 Positive_regulation of Lbx1 2 0.50 0.07 0.45
183 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
184 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
185 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
186 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
187 INT67098 Regulation of MIB1 3 0.24 4.23 0.42
188 INT193856 Localization of Psen1 19 0.73 9.79 0.41
189 INT325217 Regulation of Positive_regulation of Hand2 1 0.21 0.32 0.41
190 INT237457 Positive_regulation of Gene_expression of MESP1 1 0.02 0.45 0.4
191 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
192 INT194745 Regulation of Regulation of Hand2 1 0.03 0.95 0.39
193 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
194 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
195 INT103361 Negative_regulation of Lbx1 2 0.57 0 0.37
196 INT226424 Negative_regulation of Transcription of Hand2 1 0.08 0.66 0.37
197 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
198 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
199 INT252590 Regulation of Transcription of Hand1 1 0.36 0.76 0.36
200 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox