GO:0001950

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Name plasma membrane enriched fraction
Categary Component
Go Slim No
Go Link GO:0001950
Unique Molecular Interactions 40
Total Molecular Interactions 46
Total Single Events 1010
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for plasma membrane enriched fraction. They are ordered first by their pain relevance and then by number of times they were reported for plasma membrane enriched fraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT45376 Binding of Cpe and Mme 1 0.07 0.32 2.13
2 INT45665 Fpr1 Negative_regulation of Mme 1 0.13 0 1
3 INT34837 Maob Regulation of Negative_regulation of Mme 1 0.48 0.15 0.92
4 INT92423 EC3 Negative_regulation of Mme 1 0.02 0.28 0.86
5 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
6 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
7 INT36219 Mme Positive_regulation of Protein_catabolism of Penk 1 0.39 0 0.72
8 INT31243 Binding of Mme and Cpe 1 0.01 0 0.72
9 INT29380 Binding of gp and Mme 1 0.01 0 0.71
10 INT29381 gp Regulation of Mme 1 0.01 0 0.65
11 INT29382 Positive_regulation of gp Regulation of Mme 1 0.02 0 0.65
12 INT79210 Hps4 Negative_regulation of Mme 1 0.00 0 0.62
13 INT47284 Binding of Mme and Ctsa 1 0.21 0 0.57
14 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
15 INT54239 Binding of Mme and Nts 1 0.21 0 0.54
16 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
17 INT88696 Tac1 Regulation of Regulation of Mme 1 0.00 0.39 0.48
18 INT41039 Thop1 Positive_regulation of Mme 1 0.01 0 0.45
19 INT92422 Mme Negative_regulation of EC3 1 0.01 0.14 0.43
20 INT37328 Binding of PDYN and Mme 1 0.02 0 0.34
21 INT24127 Cast Positive_regulation of Mme 1 0.15 0 0.33
22 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
23 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
24 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
25 INT160464 Binding of Mme and Lnpep 1 0.31 0.37 0.24
26 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
27 INT118127 Binding of STXBP3 and Stx4 1 0.01 0.24 0.15
28 INT118126 Binding of STXBP3 and Snap23 1 0.18 0.24 0.15
29 INT270355 Vcsa1 Positive_regulation of Negative_regulation of Mme 1 0.13 0.52 0.12
30 INT43095 Binding of Ace and Mme 1 0.26 0 0.12
31 INT36128 Binding of Scd1 and Mme 1 0.00 0 0.09
32 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06
33 INT185388 Binding of PVRL1 and TLR2 1 0.15 0.75 0.04
34 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
35 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0
36 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
37 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0
38 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0
39 INT97223 Gm9902 Regulation of Negative_regulation of Mme 1 0.00 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for plasma membrane enriched fraction. They are ordered first by their pain relevance and then by number of times they were reported in plasma membrane enriched fraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9
2 INT5539 Negative_regulation of Mme 75 0.59 28.91 41.84
3 INT11292 Gene_expression of Mme 77 0.78 20.98 35.85
4 INT9490 Regulation of Mme 44 0.56 6.69 19.21
5 INT15237 Protein_catabolism of Mme 31 0.96 10.26 16.69
6 INT15166 Positive_regulation of Mme 40 0.70 13.01 16.24
7 INT14453 Localization of Mme 44 0.80 2.46 14.75
8 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63
9 INT8603 Binding of Mme 28 0.48 1.42 7.64
10 INT28389 Negative_regulation of Ptpra 5 0.37 0.4 3.69
11 INT35910 Binding of Mme 8 0.37 4.79 3.16
12 INT37111 Regulation of Negative_regulation of Mme 7 0.44 2.61 3.13
13 INT35548 Regulation of Mme 9 0.45 10.62 2.97
14 INT12887 Positive_regulation of Mme 9 0.60 15.41 2.93
15 INT11291 Positive_regulation of Gene_expression of Mme 6 0.61 5.93 2.81
16 INT7148 Negative_regulation of Negative_regulation of Mme 6 0.42 2.19 2.74
17 INT9721 Gene_expression of Ptpra 3 0.26 5.97 2.38
18 INT26514 Regulation of Gene_expression of Mme 2 0.41 1.18 2.27
19 INT51980 Protein_catabolism of Mme 6 0.89 2.49 2.06
20 INT71870 Positive_regulation of Gene_expression of Mme 6 0.48 4.27 2
21 INT23668 Binding of Stx3 1 0.01 0 1.31
22 INT43941 Transcription of Mme 6 0.68 0.78 1.26
23 INT43940 Regulation of Transcription of Mme 1 0.44 0 1.22
24 INT185396 Gene_expression of PVRL1 17 0.34 15.18 1.18
25 INT34704 Positive_regulation of Negative_regulation of Mme 6 0.47 0.17 1.17
26 INT25401 Negative_regulation of Gene_expression of Mme 2 0.43 0.08 1.1
27 INT7149 Phosphorylation of Mme 3 0.60 0.34 0.97
28 INT21842 Regulation of Protein_catabolism of Mme 1 0.19 0.58 0.97
29 INT9722 Negative_regulation of Gene_expression of Ptpra 1 0.15 0.8 0.96
30 INT43648 Positive_regulation of Binding of Mme 3 0.50 0.24 0.94
31 INT37377 Negative_regulation of Binding of Mme 2 0.38 1.79 0.88
32 INT47740 Regulation of Regulation of Mme 2 0.24 0.52 0.8
33 INT23671 Negative_regulation of Stx3 1 0.01 0 0.75
34 INT15055 Regulation of Negative_regulation of Mme 2 0.42 0.24 0.67
35 INT37329 Regulation of Binding of Mme 1 0.27 0 0.65
36 INT37094 Positive_regulation of Negative_regulation of Mme 2 0.50 1.15 0.51
37 INT217393 Negative_regulation of Gene_expression of Mme 3 0.43 5.98 0.46
38 INT185393 Regulation of PVRL1 4 0.24 1.48 0.45
39 INT77688 Transcription of Mme 2 0.53 4.01 0.45
40 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44
41 INT35545 Negative_regulation of Protein_catabolism of Mme 1 0.31 0 0.43
42 INT77687 Regulation of Gene_expression of Mme 3 0.44 2.75 0.4
43 INT71869 Localization of Mme 2 0.70 2.13 0.37
44 INT185401 Regulation of Gene_expression of PVRL1 1 0.27 4.69 0.34
45 INT110365 Negative_regulation of Positive_regulation of Mme 1 0.39 0.09 0.32
46 INT37120 Negative_regulation of Localization of Mme 1 0.42 0.07 0.32
47 INT84037 Negative_regulation of Regulation of Mme 1 0.37 0.64 0.26
48 INT120216 Regulation of RYR2 2 0.28 1.03 0.22
49 INT329792 Positive_regulation of Positive_regulation of Mme 1 0.23 1.17 0.13
50 INT165787 Positive_regulation of RYR2 2 0.23 1.3 0.11
51 INT185394 Binding of PVRL1 5 0.14 2.94 0.09
52 INT185395 Regulation of Regulation of PVRL1 1 0.17 0.53 0.08
53 INT192016 Localization of RYR2 5 0.25 4.18 0.05
54 INT192012 Binding of RYR2 2 0.30 3.61 0.05
55 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05
56 INT263800 Positive_regulation of Gene_expression of PVRL1 1 0.22 1.14 0.05
57 INT352210 Negative_regulation of Transcription of Mme 1 0.43 1.16 0.04
58 INT352204 Negative_regulation of Positive_regulation of Mme 1 0.38 1.59 0.04
59 INT352212 Positive_regulation of Transcription of Mme 1 0.46 1.16 0.04
60 INT192023 Negative_regulation of RYR2 1 0.15 1.86 0.04
61 INT352209 Regulation of Regulation of Mme 1 0.27 0.63 0
62 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0
63 INT321380 Positive_regulation of Gene_expression of Ptpra 1 0.04 1 0
64 INT352203 Positive_regulation of Positive_regulation of Mme 1 0.41 0.94 0
65 INT185402 Negative_regulation of Gene_expression of PVRL1 1 0.17 1.11 0
66 INT192020 Regulation of Localization of RYR2 1 0.15 0.27 0
67 INT352206 Regulation of Transcription of Mme 1 0.24 0.63 0
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