GO:0001957

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Name intramembranous ossification
Categary Process
Go Slim No
Go Link GO:0001957
Unique Molecular Interactions 182
Total Molecular Interactions 213
Total Single Events 2190
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intramembranous ossification. They are ordered first by their pain relevance and then by number of times they were reported for intramembranous ossification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
2 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
3 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
4 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22
5 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
6 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
7 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
8 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
9 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
10 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
11 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
12 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
13 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
14 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85
15 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
16 INT106808 RECK Negative_regulation of MMP2 1 0.40 0.5 0.83
17 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
18 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
19 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
20 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
21 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
22 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
23 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
24 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
25 INT99602 ZNF398 Negative_regulation of MMP2 1 0.14 0.85 0.63
26 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
27 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
28 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
29 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
30 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
31 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
32 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57
33 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
34 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
35 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
36 INT150790 ZNF398 Positive_regulation of Localization of MMP2 1 0.04 0.51 0.53
37 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
38 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52
39 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
40 INT150792 THBS3 Negative_regulation of MMP2 1 0.11 0.49 0.51
41 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51
42 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51
43 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
44 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
45 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
46 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
47 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
48 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
49 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
50 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
51 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
52 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
53 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43
54 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
55 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
56 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
57 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37
58 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
59 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37
60 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
61 INT99603 ZNF398 Regulation of Transcription of MMP2 1 0.15 0.44 0.33
62 INT99598 ZNF398 Negative_regulation of Gene_expression of MMP2 1 0.10 0.44 0.33
63 INT340615 COL4A4 Regulation of MMP2 1 0.11 0.95 0.32
64 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
65 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
66 INT99601 ZNF398 Negative_regulation of Transcription of MMP2 1 0.10 0.41 0.3
67 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
68 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
69 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
70 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
71 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
72 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
73 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27
74 INT148223 CXCL14 Regulation of Localization of Mmp2 1 0.01 0.71 0.26
75 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
76 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
77 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24
78 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
79 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
80 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23
81 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
82 INT173558 CTSK Positive_regulation of Protein_catabolism of COL5A2 1 0.00 0.53 0.22
83 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
84 INT205057 MMP3 Negative_regulation of MMP2 1 0.35 3.02 0.2
85 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
86 INT304279 ETS1 Positive_regulation of MMP2 1 0.05 1.83 0.17
87 INT185810 Binding of MMP2 and SPP1 1 0.14 0.34 0.17
88 INT304282 ETS1 Positive_regulation of Gene_expression of MMP2 1 0.05 1.83 0.17
89 INT220531 Atf3 Negative_regulation of Gene_expression of Mmp2 1 0.02 1.09 0.16
90 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16
91 INT85274 SGCG Positive_regulation of Mmp2 1 0.09 0.46 0.16
92 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
93 INT245314 Binding of HYAL1 and MMP2 1 0.16 0.29 0.15
94 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15
95 INT245312 Negative_regulation of Binding of HYAL1 and MMP2 1 0.19 0.29 0.15
96 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15
97 INT34484 FPR1 Positive_regulation of Localization of MMP2 1 0.36 0.15 0.15
98 INT195443 MMP2 Positive_regulation of Protein_catabolism of Mmp9 1 0.15 0.95 0.14
99 INT181997 TNFRSF11B Negative_regulation of CTSK 1 0.05 0.58 0.14
100 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14
101 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14
102 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13
103 INT290443 Gene_expression of TIMP2 Negative_regulation of MMP2 1 0.06 1.56 0.13
104 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
105 INT163404 Negative_regulation of VEGFA Positive_regulation of MMP2 1 0.48 0.07 0.12
106 INT343472 Epo Positive_regulation of Gene_expression of Mmp2 1 0.15 0.62 0.12
107 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12
108 INT245313 Negative_regulation of Binding of MMP2 and TIMP1 1 0.01 0.45 0.11
109 INT264409 MMP2 Regulation of MMP3 1 0.07 0.06 0.11
110 INT264398 MMP9 Regulation of MMP2 1 0.07 0.06 0.11
111 INT264402 MMP2 Regulation of MMP14 1 0.10 0.06 0.11
112 INT264390 MMP3 Regulation of MMP2 1 0.07 0.06 0.11
113 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1
114 INT183797 IL17A Positive_regulation of Positive_regulation of MMP2 1 0.03 0.24 0.1
115 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
116 INT294457 KLK4 Negative_regulation of MMP2 1 0.01 0 0.1
117 INT58630 Calca Negative_regulation of Positive_regulation of COL1A1 1 0.02 0.23 0.08
118 INT222983 TNF Positive_regulation of Positive_regulation of COL1A1 1 0.01 0.71 0.08
119 INT218710 MMP1 Regulation of Positive_regulation of Col1a1 1 0.00 0.15 0.07
120 INT264300 CTSK Positive_regulation of CYP27A1 1 0.03 0.69 0.07
121 INT205160 Binding of CD44 and MMP2 1 0.09 0.61 0.07
122 INT343480 Epo Positive_regulation of Mmp2 1 0.15 0.31 0.06
123 INT302980 Mmp2 Positive_regulation of Smpd3 1 0.29 0.78 0.05
124 INT275463 ZNF69 Negative_regulation of MMP2 1 0.01 0 0.05
125 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
126 INT220081 Binding of COL1A1 and MMRN1 1 0.00 0.36 0.05
127 INT209157 MMP9 Negative_regulation of MMP2 1 0.00 0.16 0.05
128 INT66856 Rln1 Positive_regulation of Localization of Mmp2 1 0.30 0 0.05
129 INT209156 MMP2 Negative_regulation of TIMP1 1 0.00 0.17 0.05
130 INT275464 ZNF69 Negative_regulation of Gene_expression of MMP2 1 0.01 0 0.05
131 INT351423 Sparc Positive_regulation of Mmp2 1 0.02 1.31 0.04
132 INT222980 TNF Positive_regulation of Localization of COL1A1 1 0.01 0.56 0.04
133 INT301130 Binding of VEGFA and Mmp2 1 0.03 1.33 0.03
134 INT199526 Ceacam1 Negative_regulation of Col1a1 1 0.01 0.06 0.03
135 INT301126 Tgm7 Regulation of Localization of Mmp2 1 0.38 0.2 0.03
136 INT222977 Positive_regulation of COL1A1 Positive_regulation of MMP1 1 0.01 0.61 0.03
137 INT222987 Positive_regulation of COL1A1 Positive_regulation of Protein_catabolism of MMP1 1 0.01 0.61 0.03
138 INT170329 Binding of Col4a1 and Col1a1 1 0.03 0.14 0.03
139 INT180565 HEYL Positive_regulation of Negative_regulation of COL1A1 1 0.01 0 0.03
140 INT180571 HEYL Positive_regulation of Protein_catabolism of COL1A1 1 0.01 0 0.03
141 INT170331 Binding of Col7a1 and Col1a1 1 0.00 0.14 0.03
142 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0
143 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
144 INT335303 Binding of IRF6 and MMP2 1 0.01 0 0
145 INT67563 TNF Positive_regulation of Localization of MMP2 1 0.00 0 0
146 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0
147 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0
148 INT180847 Binding of COL1A1 and NID2 1 0.05 0.91 0
149 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
150 INT171757 Binding of MMP2 and SLC7A5 1 0.03 0.29 0
151 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
152 INT252773 ROS1 Positive_regulation of COL1A1 1 0.05 0.57 0
153 INT283361 AXIN2 Negative_regulation of GSK 1 0.09 1.67 0
154 INT252800 ROS1 Regulation of COL1A1 1 0.05 0.57 0
155 INT335301 Binding of MMP2 and SLC15A4 1 0.00 0 0
156 INT327403 Bcl2 Positive_regulation of Localization of Mmp2 1 0.19 0.93 0
157 INT244688 Binding of Mmp16 and Mmp2 1 0.31 0.69 0
158 INT67561 TNF Positive_regulation of MMP2 1 0.00 0 0
159 INT252813 ELANE Positive_regulation of COL1A1 1 0.01 0.57 0
160 INT118660 Binding of COL1A1 and GAPDH 1 0.16 0.09 0
161 INT347123 Binding of Axin2 and Lrp1 1 0.08 0.2 0
162 INT96782 FAM176C Regulation of Gene_expression of COL1A1 1 0.32 0.05 0
163 INT180859 Binding of COL1A1 and NID1 1 0.01 0.9 0
164 INT335297 IRF6 Positive_regulation of Gene_expression of MMP2 1 0.01 0.07 0
165 INT252802 ROS1 Regulation of Gene_expression of COL1A1 1 0.05 0.58 0
166 INT252776 ELANE Regulation of Gene_expression of COL1A1 1 0.01 0.58 0
167 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
168 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0
169 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0
170 INT67562 Negative_regulation of TNF Positive_regulation of MMP2 1 0.00 0.05 0
171 INT301123 Tgm7 Regulation of Positive_regulation of Mmp2 1 0.23 1.47 0
172 INT244689 Mmp16 Regulation of Mmp2 1 0.18 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intramembranous ossification. They are ordered first by their pain relevance and then by number of times they were reported in intramembranous ossification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
2 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
3 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
4 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
5 INT34487 Localization of MMP2 56 0.81 31.41 23.61
6 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
7 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72
8 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
9 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16
10 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
11 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
12 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
13 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49
14 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42
15 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
16 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42
17 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
18 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79
19 INT108628 Regulation of MMP2 27 0.60 14.85 6.06
20 INT123551 Regulation of Mmp2 17 0.57 11.6 6
21 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
22 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
23 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41
24 INT90374 Positive_regulation of Positive_regulation of MMP2 14 0.50 10.12 5.08
25 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
26 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
27 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
28 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
29 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
30 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
31 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
32 INT106468 Regulation of Gene_expression of MMP2 11 0.50 3.53 2.77
33 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
34 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
35 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
36 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
37 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
38 INT55736 Transcription of MMP2 11 0.68 5.78 2.28
39 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
40 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
41 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
42 INT185829 Negative_regulation of Positive_regulation of MMP2 7 0.40 4.93 2.02
43 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
44 INT46332 Binding of Mmp2 10 0.34 5.63 2
45 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
46 INT153775 Positive_regulation of CTSK 9 0.52 5.44 1.9
47 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
48 INT91396 Positive_regulation of Negative_regulation of MMP2 3 0.33 0.97 1.8
49 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
50 INT47889 Binding of MMP2 9 0.41 6.37 1.68
51 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
52 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
53 INT34486 Regulation of Localization of MMP2 4 0.35 2.19 1.54
54 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
55 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
56 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
57 INT109105 Positive_regulation of Protein_catabolism of MMP2 3 0.46 1.98 1.38
58 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
59 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
60 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
61 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
62 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
63 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
64 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
65 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15
66 INT182005 Positive_regulation of Gene_expression of CTSK 7 0.52 4.01 1.08
67 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04
68 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
69 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
70 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
71 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
72 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
73 INT55738 Positive_regulation of Transcription of MMP2 3 0.65 1.79 0.92
74 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
75 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8
76 INT152290 Regulation of Transcription of Mmp2 1 0.27 0.15 0.8
77 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75
78 INT265557 Protein_catabolism of Mmp2 3 0.55 3.15 0.73
79 INT266797 Negative_regulation of Negative_regulation of Mmp2 1 0.05 0.96 0.7
80 INT143953 Regulation of Positive_regulation of MMP2 3 0.44 2.25 0.69
81 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
82 INT153773 Regulation of Gene_expression of CTSK 2 0.34 1.36 0.62
83 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56
84 INT244679 Binding of Mmp2 4 0.30 3.75 0.54
85 INT342614 Positive_regulation of Binding of Mmp2 1 0.46 0.6 0.54
86 INT68092 Negative_regulation of Localization of COL1A1 1 0.48 0 0.53
87 INT108629 Negative_regulation of Regulation of MMP2 1 0.41 0.7 0.52
88 INT96580 Negative_regulation of Protein_catabolism of MMP2 2 0.55 0.6 0.51
89 INT166100 Phosphorylation of MMP2 1 0.32 0.56 0.51
90 INT8886 Regulation of Transcription of Col1a1 1 0.04 0 0.5
91 INT145144 Positive_regulation of Negative_regulation of Mmp2 1 0.11 0.7 0.46
92 INT133316 Localization of CTSK 5 0.52 2.43 0.43
93 INT244683 Regulation of Positive_regulation of Mmp2 2 0.36 0.78 0.43
94 INT320812 Positive_regulation of Localization of COL1A1 1 0.05 1.04 0.4
95 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34
96 INT254811 Localization of Col1a1 3 0.29 1.39 0.3
97 INT291615 Negative_regulation of Localization of Col1a1 1 0.06 1.28 0.3
98 INT153774 Regulation of CTSK 2 0.28 0.1 0.29
99 INT126512 Negative_regulation of Gene_expression of Col1a1 3 0.39 2.2 0.27
100 INT176464 Protein_catabolism of Col1a1 1 0.19 0.83 0.26
101 INT29504 Negative_regulation of Localization of Mmp2 1 0.58 0.13 0.26
102 INT148219 Regulation of Localization of Mmp2 1 0.02 0.69 0.25
103 INT271432 Positive_regulation of Regulation of Col1a1 1 0.10 0.61 0.24
104 INT194876 Negative_regulation of Gene_expression of CTSK 1 0.03 0.75 0.23
105 INT225109 Regulation of Localization of COL1A1 1 0.05 0.41 0.23
106 INT218694 Binding of Col1a1 2 0.21 1.52 0.21
107 INT291081 Positive_regulation of Protein_catabolism of Mmp2 1 0.29 0.96 0.2
108 INT291083 Negative_regulation of Protein_catabolism of Mmp2 1 0.24 0.96 0.2
109 INT182004 Regulation of Localization of CTSK 1 0.20 0.58 0.18
110 INT120859 Positive_regulation of Localization of Col1a1 1 0.16 0.05 0.18
111 INT187816 Positive_regulation of Transcription of Col1a1 1 0.06 0.82 0.17
112 INT275479 Negative_regulation of Transcription of MMP2 2 0.25 0.43 0.16
113 INT130000 Positive_regulation of Protein_catabolism of Col1a1 1 0.49 1.15 0.15
114 INT187815 Transcription of Col1a1 1 0.09 0.76 0.15
115 INT73297 Positive_regulation of Transcription of Col1a1 2 0.32 3.12 0.14
116 INT257290 Negative_regulation of Transcription of COL1A1 3 0.27 1.64 0.13
117 INT180590 Protein_catabolism of CTSK 1 0.64 0.25 0.12
118 INT265543 Negative_regulation of Transcription of Mmp2 1 0.09 1.27 0.1
119 INT337690 Regulation of Protein_catabolism of MMP2 1 0.02 0.26 0.09
120 INT265553 Negative_regulation of Transcription of Mmp2 2 0.30 1.18 0.08
121 INT327398 Negative_regulation of Regulation of Mmp2 1 0.28 1.25 0.07
122 INT301115 Negative_regulation of Positive_regulation of Mmp2 3 0.38 3.04 0.06
123 INT325665 Positive_regulation of Axin2 1 0.36 0.59 0.06
124 INT347118 Binding of Axin2 1 0.32 1.63 0.06
125 INT268298 Gene_expression of Fgf18 1 0.22 0.44 0.05
126 INT268307 Positive_regulation of Fgf18 1 0.25 0.44 0.05
127 INT179886 Negative_regulation of Negative_regulation of COL1A1 1 0.05 0.5 0.05
128 INT325670 Negative_regulation of Axin2 1 0.31 0.34 0.04
129 INT325666 Regulation of Axin2 1 0.32 0.31 0.04
130 INT325669 Gene_expression of Axin2 4 0.57 1.42 0.03
131 INT180589 Phosphorylation of COL1A1 3 0.34 0.37 0.03
132 INT222999 Positive_regulation of Positive_regulation of COL1A1 1 0.04 0.61 0.03
133 INT180582 Negative_regulation of Phosphorylation of COL1A1 1 0.07 0 0.03
134 INT180579 Negative_regulation of Protein_catabolism of COL1A1 1 0.07 0 0.03
135 INT226885 Regulation of Regulation of Mmp2 1 0.17 0.32 0.03
136 INT275481 Negative_regulation of Binding of MMP2 1 0.28 0.07 0.03
137 INT206617 Regulation of Gene_expression of Col1a1 2 0.06 0.49 0
138 INT257285 Positive_regulation of Transcription of COL1A1 2 0.29 1.23 0
139 INT205099 Positive_regulation of Gene_expression of AXIN2 1 0.48 3.48 0
140 INT245725 Positive_regulation of Negative_regulation of Col1a1 1 0.21 0.7 0
141 INT205105 Gene_expression of AXIN2 1 0.74 6.6 0
142 INT91528 Transcription of CTSK 1 0.69 0 0
143 INT252761 Positive_regulation of Regulation of COL1A1 1 0.08 0.17 0
144 INT349649 Negative_regulation of Localization of Col1a1 1 0.04 0 0
145 INT264310 Regulation of Col1a1 1 0.19 0 0
146 INT277704 Regulation of Regulation of COL1A1 1 0.08 0.61 0
147 INT349907 Negative_regulation of Gene_expression of Axin2 1 0.32 0 0
148 INT283562 Positive_regulation of Protein_catabolism of Mmp2 1 0.05 0.34 0
149 INT209434 Negative_regulation of Protein_catabolism of Col1a1 1 0.10 0 0
150 INT343454 Phosphorylation of Mmp2 1 0.19 0.1 0
151 INT145371 Negative_regulation of AXIN2 1 0.34 0 0
152 INT342613 Negative_regulation of Binding of Mmp2 1 0.40 0.08 0
153 INT251046 Localization of Axin2 1 0.53 0 0
154 INT254803 Positive_regulation of Localization of Col1a1 1 0.10 0.11 0
155 INT165561 Negative_regulation of Negative_regulation of Mmp2 1 0.00 0.07 0
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