GO:0001959

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Name regulation of cytokine-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0001959
Unique Molecular Interactions 31
Total Molecular Interactions 39
Total Single Events 315
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for regulation of cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59
2 INT339493 Binding of Irak1 and Irak3 1 0.02 0.17 0.41
3 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
4 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
5 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
6 INT206208 MRO Negative_regulation of CD24 1 0.02 1.87 0.32
7 INT324801 Positive_regulation of Binding of Chuk and Irak1 1 0.03 0.86 0.28
8 INT324810 Binding of Chuk and Irak1 1 0.02 0.85 0.28
9 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
10 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
11 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
12 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
13 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15
14 INT206209 MRO Negative_regulation of Transcription of CD24 1 0.02 0.76 0.14
15 INT334257 Binding of Irak1 and Irak4 1 0.33 0.49 0.12
16 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
17 INT339498 Binding of Il1rap and Positive_regulation of Irak1 1 0.01 0 0.1
18 INT334266 Binding of Irak1 and Myd88 2 0.35 0.16 0.09
19 INT334268 Irak4 Positive_regulation of Irak1 1 0.47 0.37 0.09
20 INT335771 MIR155 Regulation of IRAK1 1 0.04 0.29 0.09
21 INT334255 Irak4 Positive_regulation of Phosphorylation of Irak1 1 0.32 0.38 0.09
22 INT334259 Negative_regulation of Binding of Irak1 and Irak4 1 0.29 0.33 0.04
23 INT206207 Binding of SLEB1 and CD24 1 0.03 0.87 0.03
24 INT206211 MRO Regulation of Negative_regulation of CD24 1 0.01 0.1 0.03
25 INT348039 Binding of Myd88 and Irak2 1 0.22 0 0
26 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0
27 INT348020 Binding of Traf6 and Irak2 1 0.13 0.05 0
28 INT348037 Irak2 Positive_regulation of Binding of Traf6 1 0.18 0.05 0
29 INT191801 Binding of SELP and CD24 1 0.12 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in regulation of cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
2 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34
3 INT208890 Gene_expression of Irak1 7 0.65 2.42 1.87
4 INT206244 Binding of CD24 7 0.48 5.71 1.43
5 INT191804 Transcription of CD24 10 0.72 12.43 1.25
6 INT254188 Positive_regulation of Irak1 7 0.44 3.46 0.87
7 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
8 INT191806 Positive_regulation of Gene_expression of CD24 13 0.70 9.94 0.79
9 INT191811 Regulation of CD24 7 0.45 6 0.72
10 INT168411 Binding of Irak1 1 0.18 1.08 0.68
11 INT323751 Gene_expression of IRAK1 3 0.44 1.33 0.6
12 INT334219 Phosphorylation of Irak1 6 0.73 1.21 0.55
13 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53
14 INT334230 Negative_regulation of Irak1 2 0.38 0.3 0.51
15 INT64961 Binding of Cd24 4 0.15 0.64 0.5
16 INT326696 Regulation of Cd24a 2 0.44 0 0.48
17 INT191803 Positive_regulation of CD24 6 0.70 5.49 0.43
18 INT323739 Regulation of IRAK1 3 0.23 1.73 0.43
19 INT270000 Localization of IRAK1 3 0.73 0.82 0.43
20 INT343891 Positive_regulation of Gene_expression of IRAK1 1 0.23 0.3 0.42
21 INT334241 Binding of Irak1 1 0.43 1.09 0.38
22 INT324756 Regulation of Irak1 5 0.40 0.87 0.35
23 INT191805 Negative_regulation of CD24 4 0.58 0.61 0.32
24 INT191809 Regulation of Gene_expression of CD24 5 0.45 3.04 0.31
25 INT332501 Negative_regulation of Negative_regulation of CD24 1 0.24 0.23 0.22
26 INT334224 Positive_regulation of Phosphorylation of Irak1 1 0.44 0.12 0.19
27 INT324780 Localization of Irak1 1 0.33 1.03 0.19
28 INT206238 Negative_regulation of Transcription of CD24 1 0.43 1.1 0.18
29 INT206239 Regulation of Transcription of CD24 1 0.45 0.96 0.17
30 INT206805 Negative_regulation of Gene_expression of CD24 1 0.43 1.48 0.16
31 INT191810 Positive_regulation of Transcription of CD24 3 0.60 2.88 0.15
32 INT298988 Positive_regulation of Gene_expression of Irak1 2 0.44 0.25 0.14
33 INT323746 Phosphorylation of IRAK1 1 0.46 0.81 0.12
34 INT280912 Gene_expression of Irak2 1 0.36 0.88 0.12
35 INT323732 Regulation of Gene_expression of IRAK1 1 0.26 0.82 0.12
36 INT346495 Positive_regulation of Irak1 1 0.45 0.33 0.11
37 INT335789 Negative_regulation of Transcription of IRAK1 1 0.22 0.45 0.11
38 INT206251 Protein_catabolism of CD24 1 0.66 0.62 0.11
39 INT335817 Transcription of IRAK1 1 0.35 0.45 0.11
40 INT335806 Negative_regulation of IRAK1 1 0.30 0.36 0.1
41 INT270150 Positive_regulation of Positive_regulation of Irak1 3 0.25 0.91 0.09
42 INT270154 Regulation of Positive_regulation of Irak1 1 0.19 0.48 0.09
43 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09
44 INT254732 Localization of Cd24 1 0.12 0.46 0.09
45 INT334238 Positive_regulation of Binding of Irak1 1 0.44 0.14 0.09
46 INT355318 Positive_regulation of Gene_expression of Cd24a 1 0.47 1.17 0.09
47 INT334231 Positive_regulation of Regulation of Irak1 1 0.44 0.63 0.08
48 INT254740 Negative_regulation of Cd24 1 0.07 0.08 0.07
49 INT334235 Negative_regulation of Binding of Irak1 1 0.38 0.33 0.04
50 INT326709 Negative_regulation of Gene_expression of Cd24a 3 0.40 0.86 0
51 INT206806 Phosphorylation of CD24 2 0.63 1.35 0
52 INT200854 Transcription of Cd24a 2 0.66 0.4 0
53 INT355323 Negative_regulation of Cd24a 1 0.40 0.08 0
54 INT191808 Localization of CD24 1 0.74 1.6 0
55 INT302001 Positive_regulation of Binding of CD24 1 0.21 0.42 0
56 INT347997 Phosphorylation of Irak2 1 0.38 0 0
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