GO:0001960

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Name negative regulation of cytokine-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0001960
Unique Molecular Interactions 251
Total Molecular Interactions 365
Total Single Events 3198
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
2 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
3 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
4 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64
5 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
6 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
7 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
8 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
9 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88
10 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
11 INT187226 Vip Positive_regulation of Gene_expression of Il1rn 1 0.04 0.96 0.82
12 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68
13 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
14 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
15 INT92872 SON Positive_regulation of IL1RN 1 0.06 0.64 0.65
16 INT279398 Binding of IL1RN and Il1rn 1 0.00 0.51 0.63
17 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63
18 INT255997 Binding of Il1rn and H7 1 0.01 1.21 0.63
19 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61
20 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61
21 INT179850 Binding of Ecm1 and Il11 1 0.02 0 0.6
22 INT327166 RETNLB Regulation of IL36RN 1 0.00 2.25 0.59
23 INT85487 IL1RN Negative_regulation of IL1R1 1 0.02 0 0.57
24 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57
25 INT143940 Il1rn Negative_regulation of Il1f5 1 0.00 0.51 0.57
26 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
27 INT85265 Binding of Il1rn and Insrr 1 0.01 0 0.54
28 INT171896 Binding of Ifnar1 and Il1rn 1 0.00 0.81 0.54
29 INT316735 Il1 Positive_regulation of Gene_expression of Il1rn 1 0.00 0.53 0.53
30 INT130726 Negative_regulation of Binding of IL1B and Il1rn 1 0.01 0.6 0.48
31 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
32 INT130723 Binding of IL1A and Il1rn 1 0.01 0.59 0.47
33 INT130724 Negative_regulation of Binding of IL1A and Il1rn 1 0.01 0.59 0.47
34 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47
35 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
36 INT339493 Binding of Irak1 and Irak3 1 0.02 0.17 0.41
37 INT171898 Il1rn Regulation of Gene_expression of Il1 1 0.02 0.92 0.4
38 INT279392 SFTPA1 Positive_regulation of IL1RN 1 0.00 0.19 0.4
39 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
40 INT237415 Il1rn Regulation of Il10 1 0.03 0.96 0.39
41 INT237417 Il1rn Regulation of Il4 1 0.02 0.96 0.39
42 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
43 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
44 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
45 INT230499 Gene_expression of Il1rn Negative_regulation of Gene_expression of Icam1 1 0.01 0.85 0.36
46 INT224584 Binding of IL1RN and SIGMAR1 1 0.00 0.73 0.36
47 INT87023 ZAK Positive_regulation of Gene_expression of IL36RN 1 0.03 0.62 0.36
48 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35
49 INT242363 Binding of Il1a and Il1rn 1 0.05 0.19 0.35
50 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35
51 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35
52 INT328043 Binding of PTPRC and Enox2 1 0.00 0.88 0.34
53 INT328044 Positive_regulation of Binding of PTPRC and Enox2 1 0.00 0.89 0.34
54 INT92871 Positive_regulation of SON Positive_regulation of IL1RN 1 0.06 0.33 0.34
55 INT328045 Binding of PTPRC and Tag 1 0.00 0.88 0.34
56 INT206609 Binding of Col7a1 and Ecm1 1 0.00 0.47 0.33
57 INT206608 Binding of Ecm1 and Itgb5 1 0.02 0.41 0.33
58 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
59 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
60 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
61 INT256001 Ang Negative_regulation of Il1rn 1 0.11 0.25 0.27
62 INT255996 H7 Negative_regulation of Il1rn 1 0.01 0.25 0.27
63 INT222986 PTPRC Positive_regulation of SMN1 1 0.01 0.46 0.26
64 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
65 INT222975 PTPRC Positive_regulation of VIM 1 0.05 0.46 0.26
66 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
67 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
68 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
69 INT111313 IL36RN Positive_regulation of Gene_expression of MGST1 1 0.07 0.66 0.22
70 INT180670 Cpd Regulation of Protein_catabolism of Ecm1 1 0.04 0.14 0.22
71 INT220243 IL1RN Negative_regulation of Gene_expression of DPEP1 1 0.20 0.22 0.19
72 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
73 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17
74 INT173938 Il1rn Negative_regulation of Il1 1 0.00 0.18 0.17
75 INT96559 Binding of PTPRC and KRT20 2 0.33 1.99 0.16
76 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16
77 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
78 INT259628 Cxcl10 Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.64 0.15
79 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
80 INT153154 OPN1MW Regulation of PTPRF 1 0.03 0.51 0.14
81 INT222783 Binding of MR1 and PTPRC 1 0.00 0.46 0.14
82 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
83 INT250857 Gene_expression of Mmp3 Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.17 0.13
84 INT250869 Mia Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.25 0.12
85 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12
86 INT220240 IL1RN Negative_regulation of Gene_expression of MOCS1 1 0.01 0 0.12
87 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12
88 INT277984 Negative_regulation of Epo Positive_regulation of Localization of Ptprc 1 0.02 0.77 0.12
89 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
90 INT186243 IL36RN Positive_regulation of B4GALNT1 1 0.00 0.43 0.12
91 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
92 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
93 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
94 INT306925 IL36RN Positive_regulation of HAMP 1 0.01 1.39 0.1
95 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
96 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
97 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09
98 INT33808 IL36RN Regulation of Regulation of LIPE 1 0.13 0.09 0.09
99 INT324829 ROS1 Positive_regulation of Gene_expression of Ecm1 1 0.00 0.66 0.09
100 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 0.02 0.17 0.09
101 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09
102 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
103 INT253300 Itgam Positive_regulation of Gene_expression of Ptprc 1 0.19 0.11 0.09
104 INT37238 Nono Positive_regulation of IL36RN 1 0.00 0.32 0.09
105 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
106 INT336634 Fbln1 Positive_regulation of Ecm1 1 0.06 1.26 0.09
107 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
108 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09
109 INT226044 Lta Positive_regulation of Ecm1 1 0.02 0.44 0.08
110 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08
111 INT220248 IL1RN Regulation of Gene_expression of LONP1 1 0.04 0 0.08
112 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
113 INT220241 IL1RN Regulation of Gene_expression of DPEP1 1 0.24 0 0.08
114 INT179847 Binding of Ecm1 and Sparc 1 0.04 0 0.08
115 INT103810 Binding of PTPRC and RPL26 1 0.09 1.01 0.08
116 INT220238 IL1RN Regulation of Protein_catabolism of DPEP1 1 0.14 0 0.08
117 INT231507 Binding of Ptprc and Tlr4 2 0.21 1.22 0.06
118 INT236363 Regulation of Binding of Ptprc and Tlr4 1 0.25 1.23 0.06
119 INT179852 Binding of PTPRC and Ecm1 1 0.00 0 0.05
120 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
121 INT226043 Epo Positive_regulation of Ecm1 1 0.04 1.35 0.05
122 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
123 INT227072 Binding of LTF and PTPRC 1 0.00 0.51 0.04
124 INT179836 Il11 Regulation of Gene_expression of Ecm1 1 0.05 0 0.04
125 INT336639 PTPRC Positive_regulation of Ecm1 1 0.00 0.62 0.04
126 INT219230 Binding of Ecm1 and Ighv10-3 1 0.00 0.26 0.04
127 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
128 INT288199 Binding of Ptprc and Trav6-3 1 0.00 0.05 0.03
129 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
130 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
131 INT220236 Positive_regulation of IL1RN Negative_regulation of Gene_expression of MOCS1 1 0.01 0 0.03
132 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
133 INT336637 Binding of PTPRC and Fn1 1 0.00 0.32 0
134 INT321102 Binding of F5 and PTPRC 1 0.01 0.35 0
135 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
136 INT340423 Il1rn Regulation of Binding of Ccl2 1 0.21 0.99 0
137 INT318544 Paics Regulation of Ecm1 1 0.00 1.43 0
138 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0
139 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
140 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
141 INT349219 PTPRC Positive_regulation of Gene_expression of SLC3A2 1 0.11 0.53 0
142 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
143 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
144 INT164244 Binding of IL1RN and Mmp3 1 0.01 0 0
145 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
146 INT179848 Binding of Ecm1 and Gtf3a 1 0.00 0.19 0
147 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
148 INT280961 Binding of Cav1 and Cpox 1 0.04 0 0
149 INT296211 Binding of Ptprc and Tg(CAG-EGFP)D4Nagy 1 0.01 0.13 0
150 INT222474 Binding of Fgf1 and Ecm1 1 0.00 0.62 0
151 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
152 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
153 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
154 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
155 INT180672 Sgk1 Regulation of Ecm1 1 0.03 0 0
156 INT288590 Binding of Cav1 and Abhd14a 1 0.00 0 0
157 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
158 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0
159 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
160 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
161 INT314374 Binding of Ptprc and Thy1 1 0.04 0.85 0
162 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
163 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
164 INT164240 Negative_regulation of Il1rn Negative_regulation of Mmp3 1 0.00 0 0
165 INT228288 Binding of ENG and Ptprc 1 0.06 0.25 0
166 INT336640 Binding of PTPRC and Fbln1 1 0.01 0.32 0
167 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
168 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0
169 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0
170 INT313079 SIGIRR Regulation of Tlr2 1 0.18 0.09 0
171 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
172 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
173 INT164245 Negative_regulation of Binding of IL1RN and Mmp3 1 0.01 0 0
174 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
175 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
176 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
177 INT228285 Binding of Ptprc and Nt5e 1 0.06 0.25 0
178 INT313081 SIGIRR Regulation of Tlr4 1 0.41 0.09 0
179 INT351678 Nrp1 Regulation of Binding of Ecm1 1 0.00 1.55 0
180 INT298103 Binding of Cav1 and Ca2 1 0.03 0 0
181 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
182 INT220518 Cav1 Negative_regulation of Akt1 1 0.04 1.02 0
183 INT245865 Binding of Cd34 and Ptprc 1 0.04 0 0
184 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
185 INT288592 Binding of Cav1 and Olfr1012 1 0.01 0 0
186 INT351681 Binding of Ecm1 and Fn1 1 0.00 1.14 0
187 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0
188 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
189 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
190 INT208517 Binding of PAEP and PTPRC 1 0.02 0 0
191 INT298104 Ca2 Negative_regulation of Cav1 1 0.04 0.09 0
192 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0
193 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
194 INT231510 Binding of Ptprc and Gopc 1 0.07 0.17 0
195 INT186415 IL1RN Regulation of Gene_expression of IL1B 1 0.25 0.67 0
196 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
197 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
198 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
199 INT180673 Trib3 Regulation of Ecm1 1 0.02 0 0
200 INT220526 Binding of Akt1 and Cav1 1 0.03 1.02 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62
2 INT33542 Gene_expression of Il1rn 41 0.76 32.47 18.08
3 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66
4 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82
5 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83
6 INT72565 Localization of IL1RN 45 0.80 23.59 13.17
7 INT87844 Binding of IL1RN 40 0.41 24.37 11.92
8 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
9 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
10 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31
11 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99
12 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16
13 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
14 INT5864 Localization of IL36RN 19 0.44 14.5 6.87
15 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7
16 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
17 INT126395 Positive_regulation of Gene_expression of Il1rn 11 0.41 7.66 6.25
18 INT73902 Regulation of Gene_expression of IL1RN 6 0.61 4.59 6.14
19 INT107441 Positive_regulation of Gene_expression of Il1rn 7 0.46 3.24 5.95
20 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75
21 INT114180 Negative_regulation of Il1rn 22 0.57 11.06 5.44
22 INT73905 Transcription of IL1RN 10 0.71 9.16 5.04
23 INT114183 Positive_regulation of Il1rn 17 0.55 11.31 4.83
24 INT92199 Negative_regulation of Gene_expression of IL1RN 14 0.58 10.11 4.71
25 INT81485 Negative_regulation of IL1RN 19 0.57 8.3 4.69
26 INT36041 Negative_regulation of Gene_expression of IL36RN 11 0.11 9.47 4.46
27 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41
28 INT134968 Localization of Ecm1 20 0.32 27.27 4.31
29 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
30 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
31 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68
32 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52
33 INT83646 Binding of Il1rn 12 0.37 4.41 3.51
34 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
35 INT40232 Transcription of Il1rn 8 0.53 9.6 3.37
36 INT171233 Binding of Ecm1 25 0.07 12.41 3.36
37 INT16976 Negative_regulation of IL36RN 6 0.49 5.08 3.31
38 INT8246 Positive_regulation of IL36RN 13 0.43 9.15 3.16
39 INT171888 Binding of Il1rn 13 0.38 5.53 3.13
40 INT25601 Binding of IL36RN 5 0.35 1.93 2.9
41 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
42 INT76679 Positive_regulation of Transcription of Il1rn 1 0.37 9.13 2.55
43 INT187454 Binding of Ptprc 34 0.38 9.66 2.54
44 INT62064 Negative_regulation of Gene_expression of Il1rn 6 0.32 4.81 2.53
45 INT69981 Positive_regulation of Negative_regulation of Il1rn 2 0.09 3.28 2.48
46 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
47 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37
48 INT160080 Localization of Ecm1 6 0.15 4.86 2.36
49 INT131928 Localization of Il1rn 3 0.74 2.22 2.24
50 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
51 INT145196 Gene_expression of Irak3 5 0.23 4.23 2.13
52 INT145195 Positive_regulation of Irak3 4 0.15 3.65 2.12
53 INT21013 Regulation of Gene_expression of IL36RN 4 0.11 1.71 2.11
54 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
55 INT173931 Regulation of Gene_expression of Il1rn 3 0.60 2.68 1.84
56 INT38930 Regulation of IL36RN 4 0.21 2.14 1.8
57 INT134965 Negative_regulation of Ecm1 7 0.18 7.86 1.7
58 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
59 INT38266 Localization of PTPRC 30 0.68 17.05 1.68
60 INT53835 Negative_regulation of Localization of IL36RN 3 0.17 1.27 1.63
61 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
62 INT206528 Negative_regulation of Gene_expression of Ptprc 8 0.34 3.91 1.61
63 INT180678 Negative_regulation of Protein_catabolism of Ecm1 6 0.08 2.69 1.61
64 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59
65 INT16917 Positive_regulation of Gene_expression of IL36RN 8 0.12 6.17 1.56
66 INT25600 Regulation of Binding of IL36RN 2 0.05 1.31 1.55
67 INT21012 Regulation of Localization of IL36RN 2 0.10 0.46 1.48
68 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45
69 INT159102 Regulation of Ecm1 9 0.16 1.28 1.41
70 INT73904 Positive_regulation of Localization of IL1RN 2 0.69 1.5 1.38
71 INT92873 Positive_regulation of Positive_regulation of IL1RN 3 0.47 1.82 1.28
72 INT90771 Positive_regulation of Ptprc 20 0.48 8.43 1.27
73 INT74254 Binding of PTPRC 16 0.36 8.37 1.27
74 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26
75 INT141862 Binding of Cav1 11 0.36 1.32 1.25
76 INT206515 Regulation of Gene_expression of Ptprc 6 0.39 3.4 1.22
77 INT101022 Regulation of Il1rn 5 0.44 2.15 1.21
78 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
79 INT238377 Gene_expression of SIGIRR 1 0.65 8.59 1.12
80 INT62237 Gene_expression of Ptprf 2 0.65 1.63 1.08
81 INT180683 Positive_regulation of Protein_catabolism of Ecm1 9 0.09 2.25 1.03
82 INT147464 Binding of Ptprc 13 0.36 15.18 0.98
83 INT292529 Phosphorylation of Il1rn 1 0.09 1 0.97
84 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
85 INT145851 Negative_regulation of Positive_regulation of Il1rn 1 0.08 0.7 0.95
86 INT173929 Regulation of Il1rn 5 0.26 3.02 0.93
87 INT145852 Negative_regulation of Negative_regulation of Il1rn 1 0.08 0.69 0.93
88 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
89 INT248774 Positive_regulation of Localization of Ecm1 4 0.05 8.46 0.92
90 INT165401 Phosphorylation of IL1RN 2 0.09 1.51 0.91
91 INT255990 Localization of Il1rn 6 0.73 1.74 0.9
92 INT171889 Negative_regulation of Gene_expression of Il1rn 3 0.08 2.31 0.9
93 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88
94 INT73903 Positive_regulation of Transcription of IL1RN 2 0.69 1.15 0.87
95 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
96 INT179814 Positive_regulation of Protein_catabolism of Ecm1 5 0.06 3.38 0.85
97 INT116032 Transcription of Il1rn 4 0.70 2.19 0.84
98 INT151907 Binding of Ecm1 6 0.11 2.48 0.83
99 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
100 INT250847 Negative_regulation of Ecm1 1 0.03 1.72 0.78
101 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
102 INT238378 Negative_regulation of Gene_expression of SIGIRR 1 0.41 5.67 0.76
103 INT187381 Regulation of Localization of IL1RN 1 0.00 1.05 0.74
104 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
105 INT153667 Localization of CAV1 15 0.76 11.92 0.68
106 INT88190 Negative_regulation of Binding of Il1rn 1 0.36 0.46 0.68
107 INT171692 Regulation of Protein_catabolism of Ecm1 4 0.12 1.5 0.65
108 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
109 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
110 INT179337 Positive_regulation of Gene_expression of Ecm1 14 0.05 3.73 0.58
111 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
112 INT109505 Regulation of Ptprc 3 0.32 2.45 0.58
113 INT53841 Positive_regulation of SIGIRR 1 0.47 0.17 0.58
114 INT171693 Positive_regulation of Ecm1 5 0.09 2.14 0.55
115 INT132186 Negative_regulation of Gene_expression of Ecm1 2 0.06 1.73 0.54
116 INT143131 Regulation of Ptprc 4 0.27 2.56 0.5
117 INT114182 Negative_regulation of Positive_regulation of Il1rn 1 0.15 0 0.49
118 INT86702 Localization of Cav1 8 0.69 0.76 0.47
119 INT267615 Positive_regulation of Localization of PTPRC 3 0.01 3.41 0.46
120 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
121 INT255986 Negative_regulation of Negative_regulation of Il1rn 1 0.34 0.26 0.45
122 INT15718 Negative_regulation of Positive_regulation of IL36RN 1 0.01 0.6 0.45
123 INT15716 Positive_regulation of Localization of IL36RN 1 0.01 0.6 0.45
124 INT250837 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.1 0.44
125 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
126 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
127 INT187463 Positive_regulation of Gene_expression of Ptprc 9 0.44 2.8 0.42
128 INT323910 Negative_regulation of Positive_regulation of IL1RN 1 0.05 0.57 0.42
129 INT339480 Negative_regulation of Positive_regulation of Irak3 1 0.05 0.12 0.41
130 INT205725 Regulation of Regulation of Ecm1 1 0.03 0.1 0.4
131 INT220506 Binding of Cav1 13 0.45 5.46 0.38
132 INT168101 Positive_regulation of PTPRF 2 0.45 1.04 0.37
133 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
134 INT238374 Negative_regulation of SIGIRR 1 0.42 2.89 0.36
135 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
136 INT250834 Negative_regulation of Localization of Ecm1 1 0.04 0.58 0.34
137 INT231497 Negative_regulation of Binding of Ptprc 2 0.34 0.99 0.33
138 INT344829 Positive_regulation of Positive_regulation of Il1rn 1 0.02 0.53 0.33
139 INT147463 Positive_regulation of Binding of Ptprc 2 0.35 0.95 0.3
140 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
141 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
142 INT116035 Negative_regulation of Transcription of Il1rn 1 0.57 0.1 0.29
143 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
144 INT212615 Localization of PTPRF 2 0.68 0.34 0.28
145 INT255991 Negative_regulation of Binding of Il1rn 1 0.34 0.26 0.27
146 INT323609 Positive_regulation of Binding of Il1rn 1 0.21 0.63 0.26
147 INT80059 Negative_regulation of Ptprc 8 0.41 1.85 0.25
148 INT187465 Localization of Ptprc 8 0.62 3.71 0.25
149 INT187460 Transcription of Ptprc 2 0.44 0.51 0.25
150 INT255985 Protein_catabolism of Il1rn 1 0.52 0.37 0.25
151 INT343565 Positive_regulation of Gene_expression of Ecm1 1 0.07 0.94 0.25
152 INT254818 Positive_regulation of Positive_regulation of Ecm1 4 0.06 5.27 0.24
153 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
154 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
155 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
156 INT245156 Negative_regulation of Gene_expression of PTPRC 4 0.41 0.89 0.21
157 INT171231 Regulation of Binding of Ecm1 2 0.06 0.2 0.19
158 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
159 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
160 INT254804 Negative_regulation of Protein_catabolism of Ecm1 2 0.04 0.97 0.17
161 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
162 INT351417 Regulation of Protein_catabolism of Ecm1 1 0.00 0.98 0.17
163 INT208524 Regulation of PTPRC 7 0.11 3.22 0.16
164 INT280906 Negative_regulation of Ptprc 2 0.15 2.26 0.16
165 INT152889 Transcription of PTPRC 1 0.69 0.31 0.16
166 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
167 INT35101 Positive_regulation of Protein_catabolism of IL36RN 1 0.50 0.07 0.15
168 INT285224 Positive_regulation of Transcription of Il1rn 1 0.45 0.72 0.15
169 INT35100 Protein_catabolism of IL36RN 1 0.99 0.07 0.15
170 INT187456 Regulation of Binding of Ptprc 1 0.29 0.51 0.15
171 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
172 INT96224 Positive_regulation of Ptprf 1 0.11 0.36 0.14
173 INT214975 Localization of Cav1 7 0.75 2.7 0.13
174 INT175046 Negative_regulation of Gene_expression of Ptprc 2 0.30 0.8 0.13
175 INT187313 Regulation of PTPRF 1 0.01 0 0.11
176 INT187312 Regulation of Positive_regulation of PTPRF 1 0.03 0 0.11
177 INT294132 Positive_regulation of Positive_regulation of PTPRC 1 0.18 0.08 0.11
178 INT171221 Regulation of Gene_expression of Ecm1 1 0.06 0.08 0.1
179 INT231491 Regulation of Positive_regulation of Ptprc 1 0.35 0.18 0.1
180 INT218593 Regulation of Gene_expression of Ecm1 1 0.04 1.49 0.1
181 INT175042 Localization of Ptprc 2 0.53 1.41 0.09
182 INT231493 Positive_regulation of Binding of Ptprc 1 0.39 0.19 0.09
183 INT252746 Phosphorylation of PTPRC 2 0.24 0.41 0.08
184 INT179824 Regulation of Transcription of Ecm1 1 0.08 0 0.08
185 INT321438 Regulation of Binding of PTPRC 1 0.29 0.76 0.08
186 INT179790 Transcription of Ecm1 1 0.10 0 0.08
187 INT220491 Transcription of Cav1 2 0.54 1.1 0.07
188 INT254792 Regulation of Positive_regulation of Ecm1 2 0.06 1.86 0.07
189 INT220500 Positive_regulation of Transcription of Cav1 1 0.16 0.9 0.07
190 INT340415 Regulation of Gene_expression of Il1rn 1 0.27 1.02 0.07
191 INT231501 Negative_regulation of Positive_regulation of Ptprc 1 0.34 0.38 0.06
192 INT175044 Positive_regulation of Gene_expression of Ptprc 1 0.35 3.61 0.06
193 INT220502 Positive_regulation of Positive_regulation of Cav1 1 0.24 0.21 0.05
194 INT243416 Negative_regulation of Binding of PTPRC 1 0.42 0.45 0.05
195 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05
196 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04
197 INT298571 Positive_regulation of Binding of Ecm1 1 0.05 0 0.04
198 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
199 INT262794 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.07 0.04
200 INT348683 Positive_regulation of Positive_regulation of Ecm1 1 0.09 0.3 0.04
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