GO:0001961

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Name positive regulation of cytokine-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0001961
Unique Molecular Interactions 27
Total Molecular Interactions 45
Total Single Events 243
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
2 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
3 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
4 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
5 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
6 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
7 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35
8 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
9 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31
10 INT55252 Binding of CCK and RIPK2 1 0.40 0 0.2
11 INT40819 Binding of ADRB3 and AGPAT1 1 0.24 0 0.18
12 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
13 INT43495 Cd74 Regulation of Gene_expression of Ifng 1 0.47 0 0.14
14 INT298052 Binding of Cd74 and Vip 1 0.00 1.05 0.13
15 INT87839 Binding of Cd74 and Dcn 1 0.36 0.21 0.13
16 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
17 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
18 INT348820 Cd74 Regulation of Gene_expression of TFDP3 1 0.07 0.16 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cytokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cytokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
2 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
3 INT20459 Regulation of Ripk2 5 0.44 0 4.53
4 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
5 INT187168 Binding of Cd74 13 0.27 11.2 3.44
6 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
7 INT6025 Negative_regulation of RIPK2 4 0.57 0.96 2.82
8 INT19421 Positive_regulation of RIPK2 6 0.49 5.63 2.72
9 INT243350 Binding of CD74 2 0.11 4.86 2.72
10 INT61004 Negative_regulation of Regulation of Ripk2 1 0.41 0 2.68
11 INT37977 Negative_regulation of Ripk2 3 0.42 0.92 2.03
12 INT253975 Binding of Cd74 4 0.27 4.57 1.88
13 INT37978 Localization of Ripk2 4 0.78 0.57 1.73
14 INT55511 Positive_regulation of Binding of Ripk2 1 0.49 0.19 1.69
15 INT271443 Regulation of Cd74 1 0.33 2.73 1.4
16 INT39144 Gene_expression of RIPK2 5 0.75 2.56 1.27
17 INT38502 Gene_expression of Ripk2 3 0.65 0.17 1.16
18 INT19422 Protein_catabolism of RIPK2 2 0.86 0.62 0.97
19 INT36850 Negative_regulation of Negative_regulation of RIPK2 1 0.57 0 0.97
20 INT38426 Regulation of RIPK2 3 0.60 0.62 0.91
21 INT42076 Regulation of Negative_regulation of RIPK2 1 0.44 0.91 0.91
22 INT116058 Gene_expression of Cd74 2 0.56 0.55 0.89
23 INT55512 Positive_regulation of Localization of Ripk2 1 0.67 0.09 0.85
24 INT40227 Regulation of Positive_regulation of Ripk2 1 0.44 0 0.82
25 INT174420 Positive_regulation of Gene_expression of Cd74 3 0.20 1.92 0.81
26 INT37975 Negative_regulation of Binding of Ripk2 1 0.57 0 0.75
27 INT116060 Negative_regulation of Gene_expression of Cd74 1 0.12 0 0.61
28 INT271439 Positive_regulation of Localization of Cd74 1 0.36 1.01 0.52
29 INT40820 Binding of AGPAT1 1 0.32 0 0.51
30 INT19420 Positive_regulation of Positive_regulation of RIPK2 1 0.49 0.59 0.5
31 INT271435 Localization of Cd74 1 0.54 0.95 0.49
32 INT174418 Regulation of Gene_expression of Cd74 1 0.04 0.9 0.46
33 INT38738 Localization of RIPK2 2 0.68 0.07 0.45
34 INT254172 Negative_regulation of Gene_expression of Cd74 1 0.24 1.03 0.44
35 INT62874 Gene_expression of CD74 1 0.00 0.64 0.37
36 INT40821 Negative_regulation of Binding of AGPAT1 1 0.39 0 0.18
37 INT201691 Binding of RIPK2 2 0.18 1.51 0.17
38 INT240596 Negative_regulation of Gene_expression of RIPK2 1 0.06 0.91 0.15
39 INT136002 Positive_regulation of Gene_expression of RIPK2 1 0.67 0.52 0.15
40 INT131015 Negative_regulation of Cd74 1 0.17 0.25 0.12
41 INT144094 Negative_regulation of Localization of Ripk2 1 0.42 0.49 0.09
42 INT324127 Positive_regulation of Cd74 2 0.07 1.34 0.04
43 INT194148 Positive_regulation of CD74 2 0.27 0.68 0
44 INT324126 Negative_regulation of Binding of Cd74 1 0.08 0.31 0
45 INT324125 Positive_regulation of Binding of Cd74 1 0.09 0.62 0
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