GO:0001968

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Name fibronectin binding
Categary Function
Go Slim No
Go Link GO:0001968
Unique Molecular Interactions 923
Total Molecular Interactions 1379
Total Single Events 11838
Pain Genes Associated 33

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fibronectin binding. They are ordered first by their pain relevance and then by number of times they were reported for fibronectin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
2 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
3 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
4 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
5 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
6 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
7 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
8 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
9 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
10 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
11 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
12 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
13 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
14 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
15 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
16 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
17 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
18 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
19 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
20 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
21 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
22 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
23 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
24 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
25 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
26 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
27 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
28 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
29 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
30 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
31 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
32 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
33 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
34 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91
35 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
36 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
37 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
38 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
39 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
40 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
41 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
42 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
43 INT16507 Binding of LPA and Crp 1 0.00 0.78 0.78
44 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
45 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
46 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
47 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
48 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
49 INT16506 Positive_regulation of Binding of LPA and Crp 1 0.00 0.78 0.78
50 INT16498 Binding of ADRA1D and LPA 1 0.10 0.78 0.78
51 INT16497 Positive_regulation of Binding of ADRA1D and LPA 1 0.10 0.78 0.78
52 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
53 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
54 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73
55 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
56 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
57 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
58 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
59 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
60 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
61 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69
62 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
63 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
64 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
65 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
66 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
67 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66
68 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
69 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66
70 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
71 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
72 INT224683 Mmp14 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
73 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
74 INT224684 Binding of Mmp14 and Mmp9 1 0.01 0.81 0.64
75 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64
76 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63
77 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
78 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
79 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
80 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
81 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
82 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
83 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
84 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
85 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
86 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
87 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
88 INT95434 Mmp9 Positive_regulation of Positive_regulation of Il1a 1 0.42 0.23 0.61
89 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
90 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
91 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
92 INT95432 Il1a Positive_regulation of Positive_regulation of Mmp9 1 0.37 0.25 0.6
93 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
94 INT95430 Mmp9 Positive_regulation of Mmp3 1 0.38 0.24 0.6
95 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
96 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
97 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
98 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
99 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
100 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
101 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
102 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
103 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
104 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
105 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56
106 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
107 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
108 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
109 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
110 INT282711 Binding of Csf2 and Mmp9 1 0.16 1.35 0.54
111 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
112 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
113 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
114 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
115 INT205728 Mmp9 Positive_regulation of Gene_expression of Mmp3 1 0.29 0 0.52
116 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
117 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
118 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52
119 INT205727 Mmp3 Positive_regulation of Gene_expression of Mmp9 1 0.29 0 0.52
120 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
121 INT167583 ENPP2 Positive_regulation of Gene_expression of LPA 1 0.08 0.93 0.51
122 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
123 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
124 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
125 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
126 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
127 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
128 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
129 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
130 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
131 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
132 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
133 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
134 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
135 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
136 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
137 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
138 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
139 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
140 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
141 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
142 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
143 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
144 INT173293 LPA Positive_regulation of OR1S1 1 0.03 0.15 0.47
145 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
146 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47
147 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
148 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
149 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
150 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
151 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
152 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
153 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
154 INT224674 S100a4 Positive_regulation of Gene_expression of Mmp9 1 0.03 0.85 0.45
155 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
156 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 1 0.05 0.85 0.45
157 INT314044 THL Negative_regulation of Transcription of Mmp9 1 0.20 0.81 0.45
158 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
159 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
160 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
161 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
162 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
163 INT54135 Binding of F13A1 and LPA 2 0.00 0.71 0.42
164 INT54136 Negative_regulation of Binding of F13A1 and LPA 1 0.00 0.42 0.42
165 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
166 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
167 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
168 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
169 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
170 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
171 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
172 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4
173 INT314046 THL Negative_regulation of Localization of Mmp9 1 0.13 0.95 0.39
174 INT226072 Binding of MMP9 and SHBG 1 0.15 1.02 0.39
175 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
176 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
177 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
178 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
179 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
180 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
181 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
182 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
183 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
184 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
185 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
186 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
187 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
188 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
189 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35
190 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
191 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35
192 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
193 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
194 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
195 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
196 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
197 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
198 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
199 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33
200 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33

Single Events

The table below shows the top 100 pain related interactions that have been reported for fibronectin binding. They are ordered first by their pain relevance and then by number of times they were reported in fibronectin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
5 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
6 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
7 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
8 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
9 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
10 INT99610 Localization of MMP9 126 0.79 48.46 32.67
11 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
12 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
13 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
14 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
15 INT9650 Gene_expression of LPA 141 0.75 104.57 29
16 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
17 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
18 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
19 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
20 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
21 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
22 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
23 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
24 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
25 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
26 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
27 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
28 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
29 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
30 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
31 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89
32 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
33 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
34 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
35 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
36 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
37 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
38 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
39 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16
40 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
41 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
42 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
43 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
44 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
45 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
46 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
47 INT153814 Localization of LPA 19 0.65 18.25 7.68
48 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
49 INT168600 Binding of Mmp9 14 0.44 12.79 6.92
50 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84
51 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
52 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
53 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27
54 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01
55 INT123551 Regulation of Mmp2 17 0.57 11.6 6
56 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
57 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
58 INT13170 Gene_expression of Comp 25 0.74 8.68 5.62
59 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
60 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54
61 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
62 INT1285 Localization of Mmp13 12 0.78 8.98 4.93
63 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
64 INT11030 Binding of LPA 70 0.48 40.35 4.81
65 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
66 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
67 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
68 INT160914 Positive_regulation of Positive_regulation of Mmp9 7 0.57 4.69 4.52
69 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
70 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
71 INT129964 Negative_regulation of MMP13 23 0.55 6.48 4.21
72 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18
73 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
74 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
75 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07
76 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
77 INT133312 Binding of MMP9 25 0.42 16.79 3.83
78 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
79 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75
80 INT149614 Localization of MMP13 13 0.81 6.12 3.65
81 INT32464 Regulation of Mmp13 12 0.44 6.46 3.61
82 INT161206 Negative_regulation of Localization of Mmp9 10 0.59 9.68 3.59
83 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55
84 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
85 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
86 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41
87 INT68974 Localization of Mmp9 10 0.80 4.84 3.35
88 INT43985 Regulation of LPA 29 0.62 20.79 3.29
89 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
90 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
91 INT105985 Transcription of Mmp9 11 0.66 8.55 3.02
92 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
93 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
94 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91
95 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
96 INT170305 Regulation of Gene_expression of Mmp9 11 0.33 5.7 2.8
97 INT73836 Regulation of Comp 4 0.19 4.2 2.79
98 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73
99 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
100 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
101 INT183810 Positive_regulation of Positive_regulation of MMP9 9 0.52 4.15 2.46
102 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
103 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
104 INT168603 Negative_regulation of Positive_regulation of Mmp9 3 0.37 2.32 2.42
105 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
106 INT75756 Phosphorylation of LPA 5 0.68 0.67 2.35
107 INT195080 Positive_regulation of Tnc 4 0.45 26.67 2.34
108 INT71273 Positive_regulation of Comp 8 0.42 3.8 2.32
109 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
110 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
111 INT184305 Gene_expression of Comp 53 0.77 31.66 2.2
112 INT289775 Negative_regulation of Comp 4 0.41 5.69 2.2
113 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
114 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15
115 INT27437 Negative_regulation of Comp 5 0.24 2.8 2.15
116 INT67332 Negative_regulation of ITGA4 8 0.51 7.95 2.14
117 INT50676 Regulation of ITGA4 2 0.07 0.6 2.13
118 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
119 INT125246 Negative_regulation of Positive_regulation of Mmp9 5 0.27 5.34 2.09
120 INT120106 Negative_regulation of Mmp13 8 0.51 2.25 2.08
121 INT116280 Transcription of Mmp13 11 0.67 6.52 2.06
122 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
123 INT145235 Protein_catabolism of Mmp13 3 0.89 2.46 2.03
124 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
125 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01
126 INT46332 Binding of Mmp2 10 0.34 5.63 2
127 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
128 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
129 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91
130 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
131 INT182295 Regulation of MMP13 6 0.27 3.33 1.77
132 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
133 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
134 INT168599 Phosphorylation of Mmp9 2 0.71 1.09 1.73
135 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72
136 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
137 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
138 INT168601 Negative_regulation of Phosphorylation of Mmp9 1 0.50 0.45 1.66
139 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
140 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
141 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
142 INT141147 Negative_regulation of Gene_expression of Mmp13 5 0.12 1.37 1.59
143 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57
144 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51
145 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
146 INT120111 Regulation of Mmp13 4 0.29 2.65 1.48
147 INT240359 Binding of Tnc 2 0.35 11.67 1.48
148 INT92685 Transcription of Ctgf 7 0.72 3.92 1.44
149 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
150 INT61068 Gene_expression of Igfbp3 15 0.75 8.48 1.41
151 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
152 INT168683 Localization of ITGA4 2 0.12 0.61 1.4
153 INT168685 Regulation of Localization of ITGA4 1 0.07 0.61 1.4
154 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
155 INT129963 Regulation of Gene_expression of MMP13 8 0.42 2.84 1.39
156 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
157 INT148740 Regulation of Gene_expression of Mmp13 1 0.03 2.58 1.37
158 INT123778 Positive_regulation of Positive_regulation of MMP13 4 0.25 2.51 1.34
159 INT105983 Positive_regulation of Transcription of Mmp9 3 0.48 2.82 1.34
160 INT195724 Gene_expression of SDC4 8 0.28 3.99 1.32
161 INT125897 Binding of Mmp9 3 0.36 2.36 1.32
162 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
163 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
164 INT170294 Regulation of Gene_expression of Mmp13 5 0.44 4.25 1.26
165 INT184313 Positive_regulation of Comp 4 0.55 4.23 1.24
166 INT150805 Localization of THBS1 4 0.46 2.88 1.23
167 INT120108 Transcription of Mmp13 3 0.51 0.22 1.22
168 INT317972 Positive_regulation of Transcription of Mmp13 5 0.41 3.83 1.21
169 INT333999 Protein_catabolism of Comp 1 0.72 1.77 1.19
170 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
171 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
172 INT187123 Negative_regulation of Positive_regulation of MMP9 7 0.42 2.54 1.17
173 INT86063 Positive_regulation of Positive_regulation of Mmp9 4 0.35 2.34 1.17
174 INT158565 Regulation of Ctgf 3 0.61 3.93 1.14
175 INT158563 Negative_regulation of Ctgf 6 0.56 4.31 1.12
176 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
177 INT143956 Regulation of Positive_regulation of MMP9 5 0.40 2.61 1.11
178 INT203729 Binding of Thbs1 1 0.27 3.83 1.1
179 INT220926 Transcription of MMP13 12 0.67 3.03 1.09
180 INT170321 Binding of Mmp13 3 0.36 2.54 1.09
181 INT130928 Positive_regulation of Gene_expression of Thbs1 7 0.62 5.62 1.08
182 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04
183 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
184 INT67156 Binding of ITGA4 6 0.14 2.63 1.03
185 INT206140 Negative_regulation of Gene_expression of LPA 5 0.43 3.71 1.03
186 INT173552 Protein_catabolism of Mmp13 5 0.96 3.05 1.01
187 INT105986 Positive_regulation of Transcription of Ctgf 2 0.69 2.43 1.01
188 INT316724 Negative_regulation of Localization of Mmp13 1 0.13 0.63 1
189 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
190 INT218776 Negative_regulation of Ccdc80 2 0.02 0.97 0.99
191 INT299153 Negative_regulation of Tnc 2 0.42 8.14 0.98
192 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
193 INT130005 Protein_catabolism of MMP13 4 0.36 3.02 0.95
194 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
195 INT167465 Regulation of Ccdc80 1 0.01 0.87 0.94
196 INT187135 Positive_regulation of Negative_regulation of MMP9 3 0.43 1.87 0.92
197 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
198 INT215202 Localization of Igfbp3 3 0.62 2.5 0.91
199 INT164079 Regulation of Gene_expression of CTGF 4 0.44 2 0.9
200 INT289785 Negative_regulation of Gene_expression of Comp 4 0.37 3.14 0.88
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