GO:0001970

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Name positive regulation of activation of membrane attack complex
Categary Process
Go Slim No
Go Link GO:0001970
Unique Molecular Interactions 59
Total Molecular Interactions 74
Total Single Events 823
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of activation of membrane attack complex. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of activation of membrane attack complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67
2 INT46964 C3 Positive_regulation of Tcm 1 0.00 1.26 0.66
3 INT30129 Binding of C3 and Gast 1 0.06 0.09 0.62
4 INT149479 CEBPD Positive_regulation of C3 1 0.30 0.14 0.57
5 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46
6 INT155166 Binding of C2 and C3 1 0.40 0 0.34
7 INT116358 Binding of C3 and ELANE 1 0.12 0 0.29
8 INT116356 Positive_regulation of Binding of C3 and ELANE 1 0.16 0 0.29
9 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27
10 INT24223 Ifng Negative_regulation of Gene_expression of C3 1 0.01 0 0.26
11 INT238260 Positive_regulation of pma Negative_regulation of Transcription of C3 1 0.02 0.12 0.23
12 INT218510 Binding of C3 and Cfb 1 0.02 0.53 0.2
13 INT181082 Binding of C3 and C3ar1 1 0.03 1.31 0.19
14 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19
15 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19
16 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17
17 INT244858 Lbx1 Negative_regulation of C6 1 0.28 0.09 0.17
18 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17
19 INT344590 Binding of IFN1@ and C3 1 0.32 0.3 0.16
20 INT238258 C7 Negative_regulation of C6 1 0.09 0.24 0.13
21 INT238259 Regulation of C7 Negative_regulation of C6 1 0.06 0.24 0.13
22 INT220905 Cfb Positive_regulation of C3 1 0.06 0.91 0.11
23 INT45452 Binding of C2 and C3 1 0.34 0.08 0.08
24 INT41831 Binding of ALB and C3 1 0.22 0.07 0.08
25 INT218503 Cfb Positive_regulation of C3 1 0.01 0.29 0.06
26 INT229982 Binding of C3 and amd 1 0.02 1.14 0.06
27 INT171543 IL4 Positive_regulation of Transcription of C3 1 0.28 0 0.05
28 INT171542 IL4 Positive_regulation of Gene_expression of C3 1 0.19 0 0.05
29 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05
30 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04
31 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04
32 INT281652 GOPC Positive_regulation of C3 1 0.22 0.22 0.04
33 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03
34 INT289410 Binding of C3 and Cfb 1 0.01 0.36 0.03
35 INT279533 CFH Positive_regulation of C3 1 0.07 1.8 0
36 INT229934 Binding of C3 and GPI 1 0.01 0 0
37 INT289412 Binding of C4A and C3 1 0.11 0.26 0
38 INT325596 Ly6 Positive_regulation of C6 1 0.04 0 0
39 INT254866 Positive_regulation of C3 Negative_regulation of Rock1 1 0.02 0 0
40 INT353106 Binding of amd and C3 1 0.09 1.69 0
41 INT218508 Negative_regulation of Binding of C3 and Cfb 1 0.01 0 0
42 INT254851 C3 Negative_regulation of Rhoa 1 0.06 0 0
43 INT279501 C3ar1 Positive_regulation of C3 1 0.01 0 0
44 INT254854 Positive_regulation of C3 Negative_regulation of Rhoa 1 0.05 0 0
45 INT254861 C3 Negative_regulation of Rock1 1 0.02 0 0
46 INT279530 MBL2 Positive_regulation of Positive_regulation of C3 1 0.26 1.71 0
47 INT289296 Binding of CD59 and C6 1 0.02 0.5 0
48 INT218531 Binding of C6 and TCN2 1 0.00 0 0
49 INT229930 C3AR1 Positive_regulation of C3 1 0.00 0 0
50 INT289297 Negative_regulation of Binding of CD59 and C6 1 0.02 0.51 0
51 INT229932 C4B Positive_regulation of C3 1 0.07 0 0
52 INT345059 Binding of C3 and C2 1 0.00 0 0
53 INT265546 Gla Regulation of C6 1 0.01 0.98 0
54 INT279537 ICAM3 Positive_regulation of C3 1 0.06 0.85 0
55 INT299708 Binding of C3 and PSMC2 1 0.00 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of activation of membrane attack complex. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of activation of membrane attack complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT756 Gene_expression of C3 138 0.75 100.6 19.2
2 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63
3 INT573 Negative_regulation of C3 60 0.59 41.37 7.78
4 INT178198 Gene_expression of C3 62 0.78 39.5 7.69
5 INT1120 Gene_expression of C3 33 0.67 22.86 7.56
6 INT179542 Positive_regulation of C3 27 0.52 19.39 3.83
7 INT184365 Negative_regulation of C3 19 0.43 13.86 2.89
8 INT9460 Positive_regulation of C3 6 0.69 3.96 2.81
9 INT155160 Binding of C3 20 0.47 7.77 2.61
10 INT29094 Binding of C3 39 0.37 12.65 2.27
11 INT33848 Binding of C6 6 0.36 0.88 2.04
12 INT35689 Localization of C3 17 0.75 5.3 1.98
13 INT16385 Regulation of C3 20 0.41 9.98 1.92
14 INT53493 Negative_regulation of C6 3 0.53 2.68 1.77
15 INT157719 Gene_expression of C6 8 0.67 3.41 1.74
16 INT182037 Localization of C3 10 0.68 6.69 1.54
17 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35
18 INT179539 Positive_regulation of Gene_expression of C3 9 0.70 5.98 1.32
19 INT148212 Negative_regulation of Gene_expression of C3 2 0.43 5.47 1.24
20 INT93055 Regulation of C3 4 0.40 1.81 1.12
21 INT46044 Positive_regulation of Gene_expression of C3 23 0.53 20.07 1.06
22 INT116360 Protein_catabolism of C3 19 0.64 4.4 1
23 INT238250 Regulation of Gene_expression of C3 2 0.27 2.16 0.98
24 INT110076 Regulation of C6 2 0.22 1.14 0.96
25 INT111668 Binding of C3 4 0.36 3.84 0.87
26 INT79956 Positive_regulation of Positive_regulation of C3 4 0.35 4.17 0.86
27 INT131066 Binding of C6 4 0.31 1.81 0.86
28 INT28689 Negative_regulation of Positive_regulation of C3 4 0.23 1.28 0.85
29 INT149485 Regulation of Gene_expression of C3 5 0.60 3.39 0.75
30 INT16132 Positive_regulation of C6 4 0.23 0.34 0.73
31 INT179530 Transcription of C3 4 0.69 2.59 0.7
32 INT116361 Positive_regulation of Protein_catabolism of C3 6 0.45 1.86 0.69
33 INT148686 Localization of C6 5 0.31 4.27 0.64
34 INT46173 Transcription of C3 4 0.61 3.54 0.53
35 INT22509 Positive_regulation of C6 3 0.43 0.48 0.51
36 INT58938 Gene_expression of C6 10 0.33 0.97 0.5
37 INT45447 Positive_regulation of Gene_expression of C3 2 0.42 0.9 0.49
38 INT570 Negative_regulation of C6 2 0.06 0.31 0.46
39 INT46045 Negative_regulation of Gene_expression of C3 5 0.30 3.15 0.45
40 INT220886 Regulation of C3 2 0.36 1.04 0.43
41 INT241407 Phosphorylation of C3 2 0.24 0.16 0.42
42 INT238253 Localization of C3 1 0.37 1.76 0.41
43 INT179532 Protein_catabolism of C3 5 0.26 1.61 0.34
44 INT1121 Protein_catabolism of C3 1 0.96 1.8 0.34
45 INT183446 Positive_regulation of C6 4 0.30 0.77 0.33
46 INT46174 Positive_regulation of Transcription of C3 1 0.13 0.25 0.3
47 INT279440 Binding of C6 2 0.22 0.85 0.25
48 INT238247 Transcription of C3 1 0.43 0.12 0.23
49 INT238248 Negative_regulation of Transcription of C3 1 0.26 0.12 0.23
50 INT238249 Positive_regulation of Localization of C6 1 0.20 1.2 0.22
51 INT181039 Negative_regulation of Positive_regulation of C3 1 0.32 1.42 0.22
52 INT236354 Negative_regulation of Negative_regulation of C3 2 0.25 2.19 0.21
53 INT245266 Positive_regulation of Localization of C3 1 0.23 1.11 0.21
54 INT325473 Regulation of C6 1 0.01 0.91 0.2
55 INT181041 Negative_regulation of Gene_expression of C3 1 0.32 1.37 0.2
56 INT220895 Negative_regulation of Binding of C3 3 0.28 0.95 0.16
57 INT43385 Gene_expression of C6 5 0.58 2.49 0.15
58 INT58939 Positive_regulation of Gene_expression of C6 1 0.00 0.32 0.15
59 INT79957 Regulation of Positive_regulation of C3 2 0.32 1.55 0.13
60 INT181582 Phosphorylation of C3 1 0.34 1.2 0.12
61 INT41757 Localization of C6 1 0.69 0 0.1
62 INT1122 Positive_regulation of Protein_catabolism of C3 1 0.45 0.45 0.09
63 INT334858 Positive_regulation of Phosphorylation of C3 1 0.13 0 0.06
64 INT218489 Negative_regulation of Localization of C3 1 0.08 0.24 0.04
65 INT218479 Negative_regulation of Protein_catabolism of C3 1 0.09 0.24 0.04
66 INT247840 Regulation of Gene_expression of C3 1 0.45 0.13 0.04
67 INT218481 Positive_regulation of Binding of C3 2 0.35 1.23 0.03
68 INT310104 Positive_regulation of Protein_catabolism of C6 1 0.16 0.93 0.03
69 INT334843 Negative_regulation of Phosphorylation of C3 1 0.15 0 0.03
70 INT246352 Positive_regulation of Regulation of C3 1 0.03 1.05 0.03
71 INT218480 Negative_regulation of Binding of C3 5 0.10 1.54 0
72 INT185949 Positive_regulation of Gene_expression of C6 2 0.19 0.43 0
73 INT310105 Protein_catabolism of C6 1 0.29 1.14 0
74 INT279566 Negative_regulation of Transcription of C3 1 0.30 1.49 0
75 INT218495 Negative_regulation of Negative_regulation of C3 1 0.08 0 0
76 INT73482 Protein_catabolism of C6 1 0.00 0 0
77 INT218491 Phosphorylation of C3 1 0.19 0 0
78 INT218476 Regulation of Protein_catabolism of C3 1 0.06 0 0
79 INT325555 Regulation of Gene_expression of C6 1 0.21 0 0
80 INT147305 Negative_regulation of C6 1 0.01 0 0
81 INT218483 Regulation of Binding of C3 1 0.10 0 0
82 INT279446 Regulation of Binding of C3 1 0.18 0 0
83 INT218475 Regulation of Phosphorylation of C3 1 0.10 0 0
84 INT325572 Positive_regulation of Positive_regulation of C6 1 0.23 0 0
85 INT147306 Negative_regulation of Gene_expression of C6 1 0.01 0 0
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