GO:0001994

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Name norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
Categary Process
Go Slim No
Go Link GO:0001994
Unique Molecular Interactions 44
Total Molecular Interactions 54
Total Single Events 928
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. They are ordered first by their pain relevance and then by number of times they were reported for norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
2 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1
3 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99
4 INT86960 ADRA1D Negative_regulation of Prl 1 0.00 0 0.97
5 INT106457 SPOP Positive_regulation of Negative_regulation of ADRA1D 1 0.02 0.56 0.84
6 INT16491 Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
7 INT16498 Binding of ADRA1D and LPA 1 0.10 0.78 0.78
8 INT16493 Positive_regulation of Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
9 INT16497 Positive_regulation of Binding of ADRA1D and LPA 1 0.10 0.78 0.78
10 INT18231 Binding of ADRA1D and HP 2 0.14 0.17 0.64
11 INT55873 Binding of ADRA1D and GNRH1 1 0.08 0 0.54
12 INT55872 Binding of ADRA1D and CRH 1 0.26 0 0.54
13 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
14 INT135799 Binding of Adra1d and Adra2b 1 0.02 0 0.48
15 INT47101 Adra1a Regulation of Localization of Gnrhr 1 0.02 0.24 0.44
16 INT10944 Binding of ADRA1D and TRPV1 1 0.01 0 0.35
17 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
18 INT44654 Phc1 Negative_regulation of Adra1a 1 0.00 0.4 0.33
19 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31
20 INT59326 Binding of Adra1a and Positive_regulation of Binding of Npy 1 0.44 0 0.31
21 INT39317 Binding of ADRA1D and PTAFR 1 0.54 0.54 0.3
22 INT123221 Binding of ADRA1D and TNFAIP6 1 0.03 0.76 0.25
23 INT119717 Binding of ADRA1D and F12 1 0.35 0.23 0.23
24 INT126791 RASL12 Positive_regulation of ADRA1D 1 0.24 2.62 0.22
25 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21
26 INT6697 Binding of GLUL and Positive_regulation of Positive_regulation of ADRA1D 1 0.23 0.16 0.19
27 INT28432 ADRA1D Positive_regulation of MPG 1 0.54 0.2 0.19
28 INT300563 Binding of Drd5 and ADHD1 1 0.01 1.13 0.19
29 INT45029 Binding of ADRA1D and CELA3B 1 0.32 0.17 0.17
30 INT22820 ADRA1D Regulation of ELANE 1 0.21 0 0.15
31 INT294106 Binding of DNASE1L3 and DRD5 1 0.02 0 0.14
32 INT59807 ADRA1D Positive_regulation of PLCB1 1 0.33 0 0.13
33 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
34 INT37489 Binding of ADRA1D and Alb 1 0.34 0.84 0.11
35 INT96563 Binding of ADRA1D and UCN2 1 0.19 1.34 0.1
36 INT87038 Binding of ADRA1D and Col5a3 1 0.03 0.48 0.09
37 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08
38 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03
39 INT98356 ADRA1D Positive_regulation of Positive_regulation of ESR1 1 0.02 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. They are ordered first by their pain relevance and then by number of times they were reported in norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11
2 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78
3 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87
4 INT6699 Positive_regulation of ADRA1D 65 0.70 22.72 20.31
5 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52
6 INT18658 Regulation of Adra1a 34 0.62 5.69 13.78
7 INT44 Positive_regulation of Adra1a 30 0.68 7.09 12.73
8 INT14124 Negative_regulation of Adra1a 34 0.59 7.48 10.85
9 INT348 Regulation of Adra1a 25 0.45 3.33 10.27
10 INT475 Negative_regulation of Adra1a 28 0.58 7.87 9.83
11 INT7697 Positive_regulation of Adra1a 22 0.68 2.3 9.16
12 INT1448 Binding of Adra1a 23 0.48 1.41 8.01
13 INT256 Localization of ADRA1D 11 0.78 2.91 6.85
14 INT7842 Gene_expression of Adra1a 14 0.67 1.99 6.39
15 INT335 Binding of Adra1a 16 0.36 6.16 6
16 INT29394 Gene_expression of Adra1a 9 0.77 3.62 3.91
17 INT27694 Positive_regulation of Positive_regulation of ADRA1D 10 0.70 1.52 3.57
18 INT19539 Positive_regulation of Gene_expression of ADRA1D 10 0.67 9.4 2.9
19 INT26705 Transcription of ADRA1D 6 0.67 3.99 2.74
20 INT63394 Gene_expression of Drd5 7 0.76 1.85 2.3
21 INT6521 Negative_regulation of Gene_expression of ADRA1D 4 0.57 3.19 2.14
22 INT63392 Positive_regulation of Drd5 5 0.46 1.73 2.08
23 INT15211 Localization of Adra1a 3 0.16 0 2.08
24 INT45 Negative_regulation of Positive_regulation of Adra1a 4 0.43 0.84 1.97
25 INT99387 Positive_regulation of Negative_regulation of ADRA1D 1 0.07 0.54 1.74
26 INT29395 Positive_regulation of Gene_expression of Adra1a 2 0.50 1.64 1.57
27 INT31052 Gene_expression of Adra1d 5 0.65 1.46 1.53
28 INT336571 Gene_expression of DRD5 1 0.06 0.73 1.41
29 INT14803 Positive_regulation of Positive_regulation of Adra1a 4 0.35 0.49 1.36
30 INT26703 Positive_regulation of Transcription of ADRA1D 3 0.49 1.99 1.34
31 INT6520 Regulation of Gene_expression of ADRA1D 5 0.44 1.15 1.18
32 INT103859 Positive_regulation of Drd5 2 0.49 0.81 1.14
33 INT103857 Gene_expression of Drd5 2 0.23 0.92 1.08
34 INT63393 Positive_regulation of Gene_expression of Drd5 3 0.49 1.21 1.02
35 INT26881 Regulation of Binding of ADRA1D 3 0.44 1.05 0.94
36 INT85999 Binding of Drd5 2 0.27 0.84 0.94
37 INT125157 Negative_regulation of Gene_expression of Adra1a 1 0.18 0.54 0.8
38 INT139092 Negative_regulation of Gene_expression of Adra1d 1 0.07 0 0.69
39 INT300588 Regulation of Drd5 1 0.32 0.67 0.69
40 INT139088 Positive_regulation of Gene_expression of Adra1d 1 0.05 0 0.69
41 INT184846 Negative_regulation of Drd5 1 0.19 2.28 0.68
42 INT6734 Localization of Adra1a 3 0.31 0.25 0.67
43 INT103858 Regulation of Gene_expression of Drd5 1 0.08 0.92 0.58
44 INT18657 Negative_regulation of Binding of Adra1a 2 0.43 0.17 0.56
45 INT56708 Positive_regulation of Positive_regulation of Adra1a 1 0.25 0 0.55
46 INT13738 Negative_regulation of Positive_regulation of Adra1a 3 0.29 0.08 0.52
47 INT157718 Binding of DRD5 1 0.33 0.57 0.52
48 INT21090 Regulation of Negative_regulation of Adra1a 1 0.18 0.35 0.52
49 INT61010 Negative_regulation of Regulation of ADRA1D 1 0.41 0 0.48
50 INT26917 Regulation of Adra1d 2 0.21 1.56 0.47
51 INT35592 Regulation of Regulation of ADRA1D 1 0.44 0 0.47
52 INT66593 Regulation of Gene_expression of Adra1a 2 0.05 0 0.39
53 INT102164 Positive_regulation of Binding of Adra1a 1 0.35 0.19 0.37
54 INT344086 Binding of Drd5 1 0.36 0.06 0.37
55 INT34162 Regulation of Regulation of Adra1a 1 0.02 0 0.36
56 INT19414 Positive_regulation of Localization of ADRA1D 2 0.49 0.89 0.35
57 INT113578 Negative_regulation of Adra1d 2 0.42 0.24 0.3
58 INT44623 Positive_regulation of Regulation of Adra1a 1 0.04 0.64 0.29
59 INT300593 Regulation of Gene_expression of Drd5 1 0.33 0.13 0.28
60 INT44766 Negative_regulation of Binding of ADRA1D 2 0.42 0.71 0.27
61 INT42351 Regulation of Positive_regulation of Adra1a 1 0.01 0 0.26
62 INT118118 Positive_regulation of Binding of Adra1a 1 0.18 0.3 0.26
63 INT39107 Positive_regulation of Binding of ADRA1D 1 0.49 0.52 0.25
64 INT1440 Binding of Adra1d 1 0.16 0 0.24
65 INT122590 Transcription of Adra1a 1 0.03 0.73 0.24
66 INT113577 Transcription of Adra1d 1 0.52 0.27 0.23
67 INT39288 Regulation of Binding of Adra1a 1 0.20 0.35 0.2
68 INT102528 Regulation of Positive_regulation of ADRA1D 1 0.44 0.09 0.18
69 INT31927 Positive_regulation of Localization of Adra1a 1 0.10 0.17 0.16
70 INT26455 Negative_regulation of Positive_regulation of ADRA1D 1 0.41 0.1 0.13
71 INT263872 Localization of Adra1d 1 0.01 2.5 0.11
72 INT24707 Protein_catabolism of ADRA1D 1 0.86 0.6 0.08
73 INT223763 Negative_regulation of DRD5 1 0.01 0.06 0.06
74 INT125793 Protein_catabolism of Adra1a 1 0.39 0.24 0.05
75 INT263879 Positive_regulation of Adra1d 1 0.00 0.47 0.04
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