GO:0001997

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Name positive regulation of the force of heart contraction by epinephrine-norepinephrine
Categary Process
Go Slim No
Go Link GO:0001997
Unique Molecular Interactions 36
Total Molecular Interactions 40
Total Single Events 947
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of the force of heart contraction by epinephrine-norepinephrine. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of the force of heart contraction by epinephrine-norepinephrine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1
2 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
3 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99
4 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
5 INT62250 Fdft1 Regulation of Adrb1 1 0.00 0 0.65
6 INT62249 Ghrh Regulation of Adrb1 1 0.00 0 0.62
7 INT108020 Binding of Adrb1 and Clec4d 1 0.00 1.19 0.61
8 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
9 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
10 INT47101 Adra1a Regulation of Localization of Gnrhr 1 0.02 0.24 0.44
11 INT84602 Binding of Adrb1 and Avp 1 0.00 0 0.36
12 INT35981 Adrb1 Regulation of Localization of Prl 1 0.00 0 0.36
13 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
14 INT44654 Phc1 Negative_regulation of Adra1a 1 0.00 0.4 0.33
15 INT59326 Binding of Adra1a and Positive_regulation of Binding of Npy 1 0.44 0 0.31
16 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21
17 INT75148 Binding of ADRA1B and ZNF594 1 0.00 0.16 0.18
18 INT83827 Negative_regulation of Binding of Adrb1 and Pnmt 1 0.02 0 0.1
19 INT83831 Binding of PNMT and Adrb1 1 0.02 0 0.1
20 INT83828 Binding of Adrb1 and Pnmt 1 0.01 0 0.1
21 INT83832 Negative_regulation of Binding of PNMT and Adrb1 1 0.02 0 0.1
22 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of the force of heart contraction by epinephrine-norepinephrine. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of the force of heart contraction by epinephrine-norepinephrine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
2 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
3 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
4 INT18658 Regulation of Adra1a 34 0.62 5.69 13.78
5 INT44 Positive_regulation of Adra1a 30 0.68 7.09 12.73
6 INT14124 Negative_regulation of Adra1a 34 0.59 7.48 10.85
7 INT348 Regulation of Adra1a 25 0.45 3.33 10.27
8 INT475 Negative_regulation of Adra1a 28 0.58 7.87 9.83
9 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
10 INT7697 Positive_regulation of Adra1a 22 0.68 2.3 9.16
11 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93
12 INT96 Binding of Adrb1 18 0.48 2.8 8.52
13 INT1448 Binding of Adra1a 23 0.48 1.41 8.01
14 INT26115 Gene_expression of Adrb1 14 0.64 5.13 7.78
15 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62
16 INT7842 Gene_expression of Adra1a 14 0.67 1.99 6.39
17 INT335 Binding of Adra1a 16 0.36 6.16 6
18 INT465 Binding of Adrb1 14 0.35 3.04 4.07
19 INT29394 Gene_expression of Adra1a 9 0.77 3.62 3.91
20 INT4495 Gene_expression of Adrb1 7 0.66 2.43 2.29
21 INT94 Positive_regulation of Negative_regulation of Adrb1 4 0.46 0.97 2.16
22 INT15211 Localization of Adra1a 3 0.16 0 2.08
23 INT45 Negative_regulation of Positive_regulation of Adra1a 4 0.43 0.84 1.97
24 INT23884 Negative_regulation of Negative_regulation of Adrb1 7 0.38 2.3 1.83
25 INT32176 Negative_regulation of Negative_regulation of Adrb1 2 0.40 0.4 1.77
26 INT110026 Localization of Adrb1 4 0.72 1.56 1.71
27 INT1731 Localization of Adrb1 5 0.43 0.31 1.67
28 INT29395 Positive_regulation of Gene_expression of Adra1a 2 0.50 1.64 1.57
29 INT14803 Positive_regulation of Positive_regulation of Adra1a 4 0.35 0.49 1.36
30 INT38312 Positive_regulation of Gene_expression of Adrb1 2 0.07 0.22 1.33
31 INT140159 Regulation of Gene_expression of Adrb1 1 0.00 0.17 1.07
32 INT42420 Negative_regulation of Binding of Adrb1 2 0.58 0.8 0.97
33 INT31828 Transcription of Adrb1 2 0.27 0.18 0.94
34 INT1732 Positive_regulation of Localization of Adrb1 2 0.22 0.06 0.8
35 INT125157 Negative_regulation of Gene_expression of Adra1a 1 0.18 0.54 0.8
36 INT32751 Regulation of Positive_regulation of Adrb1 2 0.36 0.07 0.77
37 INT6734 Localization of Adra1a 3 0.31 0.25 0.67
38 INT24095 Protein_catabolism of Adrb1 2 0.10 0.59 0.61
39 INT83826 Negative_regulation of Binding of Adrb1 3 0.25 0.67 0.6
40 INT29111 Negative_regulation of Positive_regulation of Adrb1 1 0.37 0.14 0.58
41 INT18657 Negative_regulation of Binding of Adra1a 2 0.43 0.17 0.56
42 INT56708 Positive_regulation of Positive_regulation of Adra1a 1 0.25 0 0.55
43 INT13738 Negative_regulation of Positive_regulation of Adra1a 3 0.29 0.08 0.52
44 INT21090 Regulation of Negative_regulation of Adra1a 1 0.18 0.35 0.52
45 INT42184 Positive_regulation of Binding of Adrb1 1 0.31 0.19 0.5
46 INT56662 Regulation of Protein_catabolism of Adrb1 1 0.05 0.27 0.5
47 INT56661 Positive_regulation of Protein_catabolism of Adrb1 1 0.06 0.27 0.49
48 INT66593 Regulation of Gene_expression of Adra1a 2 0.05 0 0.39
49 INT102164 Positive_regulation of Binding of Adra1a 1 0.35 0.19 0.37
50 INT34162 Regulation of Regulation of Adra1a 1 0.02 0 0.36
51 INT63924 Regulation of Binding of Adrb1 1 0.16 0.27 0.34
52 INT52207 Positive_regulation of Positive_regulation of Adrb1 1 0.09 0 0.33
53 INT69187 Regulation of Positive_regulation of Adrb1 1 0.25 0 0.33
54 INT44623 Positive_regulation of Regulation of Adra1a 1 0.04 0.64 0.29
55 INT10857 Regulation of Negative_regulation of Adrb1 2 0.45 0.65 0.28
56 INT42351 Regulation of Positive_regulation of Adra1a 1 0.01 0 0.26
57 INT118118 Positive_regulation of Binding of Adra1a 1 0.18 0.3 0.26
58 INT122590 Transcription of Adra1a 1 0.03 0.73 0.24
59 INT39288 Regulation of Binding of Adra1a 1 0.20 0.35 0.2
60 INT74928 Gene_expression of ADRA1B 1 0.04 0 0.18
61 INT31927 Positive_regulation of Localization of Adra1a 1 0.10 0.17 0.16
62 INT40871 Regulation of Negative_regulation of Adrb1 1 0.24 0.32 0.1
63 INT44040 Negative_regulation of Gene_expression of Adrb1 1 0.35 0.34 0.09
64 INT74929 Positive_regulation of Gene_expression of ADRA1B 1 0.02 0 0.09
65 INT45551 Regulation of Regulation of Adrb1 1 0.22 0.29 0.08
66 INT125793 Protein_catabolism of Adra1a 1 0.39 0.24 0.05
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