GO:0002011

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Name morphogenesis of an epithelial sheet
Categary Process
Go Slim No
Go Link GO:0002011
Unique Molecular Interactions 64
Total Molecular Interactions 116
Total Single Events 505
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for morphogenesis of an epithelial sheet. They are ordered first by their pain relevance and then by number of times they were reported for morphogenesis of an epithelial sheet. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
2 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
3 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
4 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
5 INT254206 Il10 Negative_regulation of Chuk 1 0.05 0.59 0.29
6 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
7 INT254208 Il10 Negative_regulation of Regulation of Chuk 1 0.05 0.59 0.29
8 INT324801 Positive_regulation of Binding of Chuk and Irak1 1 0.03 0.86 0.28
9 INT324825 Binding of Chuk and Myd88 1 0.03 0.86 0.28
10 INT324810 Binding of Chuk and Irak1 1 0.02 0.85 0.28
11 INT324806 Positive_regulation of Binding of Chuk and Myd88 1 0.04 0.86 0.28
12 INT143725 Chuk Negative_regulation of Phosphorylation of Nfkb1 1 0.17 0.71 0.26
13 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
14 INT311989 Binding of Chuk and Mthfd1 1 0.05 0.56 0.24
15 INT332968 Hoxb4 Positive_regulation of Ppara 1 0.02 0.25 0.16
16 INT222874 NDUFA6 Regulation of Chuk 1 0.01 1.57 0.15
17 INT222876 Binding of NDUFA6 and Chuk 1 0.02 2.02 0.13
18 INT222875 Binding of NDUFA6 and Positive_regulation of Chuk 1 0.01 0.74 0.13
19 INT243996 Binding of Dag1 and Dmd 1 0.04 0.08 0.11
20 INT222873 NDUFA6 Negative_regulation of Phosphorylation of Chuk 1 0.01 0.24 0.08
21 INT163618 Chuk Regulation of Rela 1 0.16 0.23 0.08
22 INT244027 Binding of Dag1 and Helt 1 0.00 0.05 0.08
23 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
24 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07
25 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
26 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07
27 INT132004 Binding of Col4a2 and Lama1 1 0.16 0.14 0.05
28 INT222878 NDUFA6 Negative_regulation of Chuk 1 0.01 2.06 0.05
29 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
30 INT303393 Binding of Jag1 and Tceb2 1 0.03 0.29 0.04
31 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
32 INT332483 Binding of JAG1 and SGPP2 1 0.21 0.23 0.04
33 INT348024 Binding of Chuk and Traf3 1 0.13 0.65 0.04
34 INT303389 Binding of Jag1 and Cul5 1 0.20 0.29 0.04
35 INT217106 Binding of Hoxa2 and Hoxb2 1 0.34 0.08 0.04
36 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
37 INT303397 Binding of Jag1 and Gopc 1 0.13 0 0
38 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
39 INT348018 Map3k7 Positive_regulation of Chuk 1 0.19 0.06 0
40 INT222868 Binding of Chuk and Pkn1 1 0.00 0 0
41 INT303398 Jag1 Positive_regulation of Protein_catabolism of Myh3 1 0.52 0 0
42 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
43 INT303405 Binding of NPAT and Jag1 1 0.39 0 0
44 INT227218 Binding of JAG1 and CD8A 1 0.05 0.5 0
45 INT163092 Notch2 Positive_regulation of Gene_expression of Fos 1 0.08 0.07 0
46 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
47 INT303404 Binding of TCAP and Jag1 1 0.39 0 0
48 INT222871 Binding of Chuk and Ikbkg 1 0.02 0 0
49 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
50 INT283122 Binding of Dag1 and Sptbn1 1 0.00 0.07 0
51 INT303399 Binding of Jag1 and Myh3 1 0.50 0.85 0
52 INT348035 Map3k7 Positive_regulation of Binding of Chuk 1 0.20 0.06 0
53 INT303391 Binding of Jag1 and Tceb1 1 0.44 0 0
54 INT222870 Traf2 Positive_regulation of Chuk 1 0.03 0.37 0
55 INT303386 Binding of Jag1 and Laptm5 1 0.02 0 0
56 INT303390 Binding of Jag1 and Myo1f 1 0.07 0 0
57 INT303400 Jag1 Positive_regulation of Protein_catabolism of Gopc 1 0.25 0 0
58 INT303395 Positive_regulation of Binding of Jag1 and Myo1f 1 0.07 0 0
59 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for morphogenesis of an epithelial sheet. They are ordered first by their pain relevance and then by number of times they were reported in morphogenesis of an epithelial sheet. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113700 Positive_regulation of Chuk 30 0.41 21.17 5.69
2 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
3 INT174958 Negative_regulation of Chuk 21 0.25 8.73 2.96
4 INT222845 Gene_expression of Chuk 27 0.52 25.15 2.67
5 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
6 INT132893 Binding of CHUK 1 0.00 0.63 2.25
7 INT132892 Positive_regulation of CHUK 3 0.08 1.62 2.01
8 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
9 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
10 INT132890 Positive_regulation of Binding of CHUK 1 0.00 0.44 1.6
11 INT132891 Gene_expression of CHUK 1 0.01 0.47 1.58
12 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
13 INT143716 Phosphorylation of Chuk 16 0.41 5.25 1.35
14 INT202817 Gene_expression of Dag1 16 0.75 7.82 1.3
15 INT217438 Binding of Chuk 24 0.25 7.29 1.29
16 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
17 INT35095 Negative_regulation of Notch2 3 0.36 0.06 1.15
18 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07
19 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
20 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
21 INT26531 Regulation of Srf 3 0.18 0.62 0.9
22 INT303347 Positive_regulation of Gene_expression of Jag1 6 0.65 4.06 0.77
23 INT45293 Transcription of Srf 2 0.47 0.79 0.76
24 INT57510 Regulation of Notch2 1 0.05 0 0.73
25 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
26 INT283119 Regulation of Dag1 4 0.44 1.98 0.65
27 INT74781 Regulation of JAG1 6 0.39 2.75 0.63
28 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63
29 INT283110 Localization of Dag1 5 0.73 3.14 0.61
30 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
31 INT151401 Localization of JAG1 4 0.65 1.88 0.58
32 INT143713 Positive_regulation of Phosphorylation of Chuk 4 0.25 1.38 0.58
33 INT223462 Binding of Hoxb4 1 0.01 0.08 0.58
34 INT79888 Gene_expression of Notch2 3 0.43 0.39 0.54
35 INT202494 Regulation of Chuk 5 0.20 2.17 0.46
36 INT222850 Positive_regulation of Gene_expression of Chuk 7 0.34 4.91 0.44
37 INT35096 Negative_regulation of Negative_regulation of Notch2 1 0.36 0 0.4
38 INT151400 Binding of JAG1 14 0.37 7.96 0.39
39 INT283120 Regulation of Gene_expression of Dag1 4 0.52 1.32 0.38
40 INT141493 Negative_regulation of CHUK 2 0.07 1.15 0.38
41 INT222838 Negative_regulation of Gene_expression of Chuk 5 0.25 3.43 0.31
42 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
43 INT278145 Positive_regulation of Positive_regulation of Chuk 2 0.29 1.45 0.28
44 INT7610 Localization of Srf 3 0.67 0.98 0.27
45 INT222844 Positive_regulation of Binding of Chuk 1 0.13 0.58 0.26
46 INT273867 Binding of Jag1 18 0.45 3.14 0.25
47 INT303374 Negative_regulation of Jag1 2 0.48 0.9 0.23
48 INT206047 Negative_regulation of Positive_regulation of Chuk 2 0.11 0.6 0.23
49 INT286203 Protein_catabolism of Dag1 2 0.26 1.56 0.22
50 INT223445 Localization of Hoxb4 1 0.01 0 0.22
51 INT316917 Negative_regulation of Protein_catabolism of Dag1 1 0.12 0.44 0.21
52 INT283102 Positive_regulation of Dag1 1 0.49 1.31 0.21
53 INT222836 Negative_regulation of Phosphorylation of Chuk 5 0.16 0.98 0.19
54 INT243937 Binding of Dag1 1 0.05 0.13 0.19
55 INT222837 Regulation of Binding of Chuk 1 0.12 1.18 0.18
56 INT283105 Positive_regulation of Gene_expression of Dag1 1 0.67 1.19 0.17
57 INT302181 Positive_regulation of Negative_regulation of Chuk 1 0.04 0.54 0.16
58 INT89766 Binding of SRF 1 0.17 0.89 0.15
59 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
60 INT243679 Protein_catabolism of Chuk 1 0.02 0 0.14
61 INT202645 Gene_expression of Hoxb4 3 0.67 0.05 0.13
62 INT283103 Regulation of Localization of Dag1 1 0.44 0.32 0.09
63 INT202489 Localization of Chuk 3 0.53 1.63 0.08
64 INT22789 Binding of Srf 1 0.37 0.07 0.07
65 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
66 INT190544 Transcription of Srf 1 0.19 0.43 0.06
67 INT190570 Localization of Srf 1 0.20 0.49 0.06
68 INT219231 Positive_regulation of Gene_expression of JAG1 1 0.40 1.18 0.05
69 INT217086 Binding of Hoxb2 1 0.40 0.08 0.04
70 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
71 INT268102 Transcription of SRF 1 0.53 0.85 0.03
72 INT225413 Binding of Srf 1 0.10 0.27 0.03
73 INT303349 Positive_regulation of Jag1 5 0.57 1.23 0
74 INT157800 Gene_expression of Srf 2 0.45 0.88 0
75 INT286388 Transcription of Jag1 2 0.65 0.64 0
76 INT163086 Positive_regulation of Notch2 2 0.31 1.29 0
77 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
78 INT202648 Positive_regulation of Gene_expression of Hoxb4 1 0.44 0.05 0
79 INT303366 Negative_regulation of Gene_expression of Jag1 1 0.55 0.48 0
80 INT163089 Negative_regulation of Gene_expression of Notch2 1 0.07 0.07 0
81 INT163088 Positive_regulation of Gene_expression of Notch2 1 0.08 0.07 0
82 INT283107 Transcription of Dag1 1 0.61 0.44 0
83 INT202479 Positive_regulation of Localization of Chuk 1 0.35 0.33 0
84 INT303370 Protein_catabolism of Jag1 1 0.62 0.05 0
85 INT257560 Regulation of Negative_regulation of JAG1 1 0.13 0.48 0
86 INT303356 Localization of Jag1 1 0.70 0.09 0
87 INT303348 Positive_regulation of Transcription of Jag1 1 0.44 0.64 0
88 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
89 INT303353 Negative_regulation of Binding of Jag1 1 0.40 0 0
90 INT283101 Negative_regulation of Gene_expression of Dag1 1 0.57 0.96 0
91 INT163087 Positive_regulation of Negative_regulation of Notch2 1 0.08 0.06 0
92 INT202650 Positive_regulation of Hoxb4 1 0.60 0 0
93 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
94 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
95 INT303367 Negative_regulation of Positive_regulation of Jag1 1 0.35 0.28 0
96 INT283113 Regulation of Transcription of Dag1 1 0.52 0.44 0
97 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
98 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
99 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
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