GO:0002026

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Name regulation of the force of heart contraction
Categary Process
Go Slim No
Go Link GO:0002026
Unique Molecular Interactions 448
Total Molecular Interactions 537
Total Single Events 4246
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of the force of heart contraction. They are ordered first by their pain relevance and then by number of times they were reported for regulation of the force of heart contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
2 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
3 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
4 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
5 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
6 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
7 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
8 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
9 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
10 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
11 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
12 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
13 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
14 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
15 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
16 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
17 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
18 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
19 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
20 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
21 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
22 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
23 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
24 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
25 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
26 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
27 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
28 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
29 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
30 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
31 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
32 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
33 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
34 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
35 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
36 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
37 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
38 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
39 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
40 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
41 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
42 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
43 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
44 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
45 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
46 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
47 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
48 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
49 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
50 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
51 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
52 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89
53 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
54 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
55 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
56 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86
57 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
58 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
59 INT291581 Pde5a Regulation of Localization of Abat 1 0.03 0 0.83
60 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
61 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
62 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
63 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
64 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
65 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
66 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
67 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
68 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
69 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
70 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
71 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
72 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
73 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
74 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75
75 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
76 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
77 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
78 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
79 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
80 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
81 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
82 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
83 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7
84 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
85 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
86 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
87 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
88 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68
89 INT169217 Binding of Pebp1 and Coc 1 0.00 0.22 0.67
90 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
91 INT89875 Pdyn Positive_regulation of Localization of Myh6 1 0.09 0 0.66
92 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
93 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
94 INT76877 Binding of Slc3a1 and Slc8a1 1 0.02 0 0.64
95 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
96 INT65256 Pebp1 Regulation of Gene_expression of Basp1 1 0.00 0.05 0.64
97 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
98 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
99 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
100 INT291579 Pde12 Regulation of Binding of Pde5a 1 0.02 0.41 0.6
101 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
102 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
103 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
104 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
105 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
106 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58
107 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
108 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
109 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
110 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
111 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
112 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
113 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
114 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
115 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
116 INT106392 ADRBK1 Regulation of Negative_regulation of OPRL1 1 0.27 0.06 0.52
117 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
118 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
119 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
120 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
121 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
122 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 0.31 0.65 0.51
123 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
124 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
125 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
126 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5
127 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
128 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
129 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
130 INT142155 Ifng Positive_regulation of Il5 1 0.08 0 0.48
131 INT291580 Pde5a Regulation of Abat 1 0.04 0.39 0.48
132 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
133 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
134 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
135 INT99790 Ifng Positive_regulation of Cxcr2 1 0.12 0.28 0.46
136 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
137 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
138 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
139 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
140 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
141 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
142 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
143 INT126338 Insrr Regulation of Gene_expression of Ifng 1 0.00 0.56 0.43
144 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43
145 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
146 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42
147 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
148 INT118519 Slc8a1 Negative_regulation of Positive_regulation of Nfkb1 1 0.16 0.59 0.42
149 INT17305 Ifng Positive_regulation of RT1-CE1 1 0.06 0.46 0.41
150 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
151 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41
152 INT17308 Ifng Positive_regulation of Atp8a1 1 0.64 0.45 0.41
153 INT257229 Binding of PRKG1 and Pde5a 1 0.01 0.17 0.41
154 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
155 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
156 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
157 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
158 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
159 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
160 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
161 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
162 INT244046 Binding of Gabrg1 and Prkca 1 0.06 0 0.39
163 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
164 INT141016 Il18 Positive_regulation of Gene_expression of Ifng 1 0.39 0.27 0.39
165 INT50624 Binding of Pebp1 and Opcml 2 0.13 0 0.38
166 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
167 INT272726 Mdk Regulation of Negative_regulation of Prkca 1 0.00 0 0.38
168 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
169 INT152361 Binding of Ifng and T2dm2 1 0.00 0.86 0.37
170 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
171 INT221259 Pde5a Positive_regulation of Localization of PRKG1 1 0.00 0.06 0.37
172 INT140569 Ifng Positive_regulation of Gene_expression of Il6 1 0.00 0.82 0.36
173 INT140571 Ifng Positive_regulation of Ifnb1 1 0.01 0.82 0.36
174 INT88192 IFNG Regulation of Gene_expression of ZAK 1 0.01 0.75 0.36
175 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
176 INT140572 Ifng Positive_regulation of Gene_expression of Ifnb1 1 0.01 0.82 0.36
177 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36
178 INT140573 Positive_regulation of Ifng Positive_regulation of Ifnb1 1 0.01 0.83 0.36
179 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
180 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
181 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
182 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35
183 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35
184 INT275094 Pde5a Regulation of Ltp 1 0.05 0 0.35
185 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
186 INT189492 Ifng Positive_regulation of Localization of Darc 1 0.00 0.53 0.34
187 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
188 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
189 INT112023 Binding of Ifng and Il10 1 0.03 0.31 0.33
190 INT112019 Binding of Ifng and Ighg1 1 0.10 0.3 0.33
191 INT137168 IFNG Positive_regulation of Gene_expression of CXCR3 1 0.32 0.34 0.32
192 INT167596 Il23a Positive_regulation of Gene_expression of Ifng 1 0.13 0.94 0.32
193 INT112022 Binding of Hand1 and Ifng 1 0.09 0.3 0.32
194 INT98013 Il18 Positive_regulation of Gene_expression of IFNG 1 0.66 0.44 0.32
195 INT106397 Positive_regulation of OPRL1 Positive_regulation of ADRBK1 1 0.46 0.09 0.31
196 INT102976 Binding of ADRBK1 and Rbm39 1 0.00 0 0.31
197 INT207631 Hspg2 Positive_regulation of Gene_expression of Prkca 1 0.03 0.08 0.31
198 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31
199 INT265138 Adrbk1 Positive_regulation of Localization of Chrm1 1 0.07 0 0.31
200 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of the force of heart contraction. They are ordered first by their pain relevance and then by number of times they were reported in regulation of the force of heart contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
2 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
3 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
4 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
5 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
6 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
7 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
8 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
9 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
10 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
11 INT8518 Localization of Ifng 53 0.81 36.68 24.13
12 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
13 INT117527 Binding of Prkca 25 0.48 6.43 21.05
14 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
15 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
16 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
17 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
18 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
19 INT19509 Localization of Ifng 55 0.78 28.25 18.67
20 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
21 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
22 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65
23 INT209 Positive_regulation of Pde5a 30 0.21 2.54 16.31
24 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
25 INT79458 Localization of Prkca 30 0.81 11.13 15.78
26 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
27 INT4931 Localization of IFNG 53 0.78 33.25 13.65
28 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
29 INT94861 Gene_expression of Pde5a 40 0.69 14.73 13.27
30 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
31 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
32 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
33 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
34 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
35 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
36 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28
37 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
38 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14
39 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
40 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
41 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
42 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
43 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
44 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
45 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
46 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
47 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
48 INT33781 Binding of Pebp1 11 0.44 1.76 6.61
49 INT1280 Negative_regulation of Pebp1 7 0.28 2.12 6.45
50 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
51 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
52 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
53 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
54 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
55 INT94862 Positive_regulation of Gene_expression of Pde5a 10 0.20 4.23 5.18
56 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92
57 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
58 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
59 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
60 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
61 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
62 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27
63 INT88182 Gene_expression of Atp2a2 40 0.78 22.91 4.26
64 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
65 INT102654 Positive_regulation of Pln 10 0.48 3.53 4.19
66 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
67 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
68 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
69 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
70 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
71 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
72 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
73 INT73127 Gene_expression of Pde5a 18 0.76 5.25 3.31
74 INT21572 Gene_expression of Pebp1 9 0.71 2.52 3.3
75 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
76 INT54709 Positive_regulation of Gene_expression of Adrbk1 6 0.49 0.18 3.12
77 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
78 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09
79 INT131472 Regulation of Pde5a 11 0.42 6.95 3.06
80 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04
81 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04
82 INT102969 Positive_regulation of Gene_expression of ADRBK1 7 0.46 1.21 2.87
83 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84
84 INT67078 Binding of Ifng 7 0.48 4.84 2.73
85 INT76875 Positive_regulation of Adm 12 0.58 3.36 2.72
86 INT136675 Transcription of Pde5a 6 0.63 4.74 2.71
87 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7
88 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
89 INT110503 Negative_regulation of ADRBK1 4 0.53 0.71 2.69
90 INT158157 Phosphorylation of Csrp3 1 0.03 1.28 2.68
91 INT94860 Negative_regulation of Gene_expression of Pde5a 2 0.33 3.2 2.64
92 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
93 INT118518 Positive_regulation of Slc8a1 7 0.56 5.31 2.59
94 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
95 INT257298 Regulation of Positive_regulation of Pde5a 1 0.19 2.03 2.54
96 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
97 INT94978 Negative_regulation of Adrbk1 6 0.38 0.13 2.47
98 INT16964 Binding of IFNG 27 0.48 14.31 2.45
99 INT257299 Binding of Pde5a 14 0.27 4.31 2.45
100 INT114011 Negative_regulation of ATP1A2 5 0.45 6.12 2.41
101 INT73980 Transcription of Ifng 12 0.72 5.42 2.4
102 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33
103 INT67437 Negative_regulation of Localization of Ifng 7 0.47 2.23 2.28
104 INT257301 Protein_catabolism of Pde5a 5 0.30 1.97 2.26
105 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
106 INT88183 Localization of Atp2a2 6 0.63 2.1 2.22
107 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
108 INT227153 Negative_regulation of PEBP1 1 0.12 0.51 2.17
109 INT72842 Phosphorylation of Adrbk1 5 0.47 0.58 2.16
110 INT146491 Binding of Adrbk1 3 0.48 1.58 2.09
111 INT108422 Binding of Pde5a 11 0.36 3.07 2.07
112 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06
113 INT111530 Positive_regulation of Regulation of Ifng 1 0.41 0.32 2.01
114 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
115 INT99426 Negative_regulation of Gene_expression of Atp2a2 19 0.59 13.7 1.96
116 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
117 INT165648 Negative_regulation of Transcription of Pde5a 1 0.41 3.6 1.93
118 INT160634 Gene_expression of Slc8a1 2 0.64 2.12 1.92
119 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89
120 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
121 INT13707 Positive_regulation of Pebp1 3 0.41 0.24 1.88
122 INT102970 Localization of ADRBK1 4 0.66 0.45 1.85
123 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
124 INT25835 Binding of Slc8a1 3 0.36 0.47 1.79
125 INT102449 Binding of ADM 12 0.33 5.85 1.73
126 INT1347 Localization of Pebp1 2 0.48 0.17 1.69
127 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68
128 INT73870 Positive_regulation of Regulation of Adrbk1 1 0.47 0.17 1.66
129 INT267806 Negative_regulation of Pln 8 0.40 4.01 1.63
130 INT73355 Negative_regulation of Slc8a1 5 0.47 2.35 1.61
131 INT113716 Positive_regulation of Transcription of Ifng 1 0.53 2.56 1.61
132 INT94965 Transcription of Adrbk1 2 0.22 0.13 1.52
133 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46
134 INT291576 Positive_regulation of Protein_catabolism of Pde5a 1 0.12 1.15 1.43
135 INT118988 Negative_regulation of Adm 3 0.10 1.05 1.41
136 INT118581 Positive_regulation of ATP1A2 3 0.21 1.81 1.4
137 INT56228 Positive_regulation of Positive_regulation of Ifng 2 0.43 2.83 1.4
138 INT102228 Localization of Adm 9 0.69 1.58 1.34
139 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
140 INT73126 Positive_regulation of Gene_expression of Pde5a 3 0.59 0.55 1.31
141 INT85765 Localization of PEBP1 3 0.73 0.83 1.3
142 INT151216 Positive_regulation of Adrbk1 2 0.46 0.9 1.3
143 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
144 INT13705 Regulation of Pebp1 2 0.26 0.85 1.3
145 INT242945 Localization of PDE5A 9 0.75 4.57 1.28
146 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26
147 INT19923 Regulation of Localization of Ifng 3 0.22 1.1 1.25
148 INT48037 Regulation of Adm 8 0.44 3.96 1.24
149 INT296914 Regulation of Pln 2 0.19 3.08 1.23
150 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
151 INT94967 Localization of Adrbk1 2 0.26 0.33 1.21
152 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
153 INT111536 Positive_regulation of Negative_regulation of Ifng 1 0.41 0.35 1.18
154 INT79598 Regulation of PDE5A 16 0.60 8.68 1.17
155 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
156 INT99427 Positive_regulation of Gene_expression of Atp2a2 5 0.64 4.13 1.14
157 INT112931 Negative_regulation of Localization of Adrbk1 1 0.37 0 1.13
158 INT103043 Binding of PDE5A 16 0.37 7.79 1.12
159 INT112932 Localization of Adrbk1 1 0.69 0 1.12
160 INT150838 Positive_regulation of Gene_expression of Adm 4 0.06 1.98 1.11
161 INT106404 Positive_regulation of Positive_regulation of ADRBK1 2 0.41 0.31 1.08
162 INT108347 Regulation of Adm 5 0.26 2.55 1.04
163 INT98849 Binding of Adrbk1 3 0.36 0.18 1.04
164 INT98855 Negative_regulation of Binding of Adrbk1 2 0.41 0.18 1.04
165 INT122884 Positive_regulation of Transcription of Ifng 1 0.39 1.08 1.03
166 INT80500 Localization of Slc8a1 4 0.61 1.37 1.02
167 INT146492 Positive_regulation of Negative_regulation of Adrbk1 1 0.50 0.74 1
168 INT33217 Positive_regulation of Csrp3 1 0.08 0.85 0.95
169 INT257200 Phosphorylation of Pde5a 1 0.25 0 0.94
170 INT33218 Gene_expression of Csrp3 1 0.24 0.84 0.94
171 INT111883 Negative_regulation of Transcription of Adrbk1 1 0.33 0 0.93
172 INT111887 Transcription of Adrbk1 1 0.56 0 0.92
173 INT225094 Localization of ADM 5 0.63 3.89 0.91
174 INT165644 Regulation of Transcription of Pde5a 1 0.44 1.65 0.91
175 INT106495 Positive_regulation of Localization of Atp2a2 1 0.37 0.19 0.91
176 INT164144 Phosphorylation of Pde5a 4 0.19 1.15 0.87
177 INT317485 Regulation of Binding of Prkca 1 0.17 0.17 0.87
178 INT118987 Localization of Adm 4 0.50 0.34 0.84
179 INT103303 Negative_regulation of Transcription of Ifng 6 0.43 2.7 0.83
180 INT43488 Regulation of Positive_regulation of Ifng 1 0.42 0.71 0.83
181 INT64635 Binding of Ifng 2 0.36 0.57 0.81
182 INT177532 Localization of Pde5a 2 0.56 0.96 0.81
183 INT11138 Regulation of Localization of Ifng 2 0.56 0.8 0.77
184 INT110511 Regulation of ADRBK1 1 0.22 0.22 0.76
185 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76
186 INT110505 Positive_regulation of Negative_regulation of ADRBK1 1 0.38 0.22 0.76
187 INT73429 Negative_regulation of Atp2a2 20 0.20 9.05 0.74
188 INT165645 Positive_regulation of Negative_regulation of Pde5a 3 0.37 1.58 0.74
189 INT54710 Regulation of Regulation of Adrbk1 1 0.37 0 0.69
190 INT165647 Negative_regulation of Negative_regulation of Pde5a 1 0.31 1.22 0.67
191 INT116009 Regulation of Negative_regulation of Ifng 1 0.44 0.09 0.67
192 INT94211 Positive_regulation of Negative_regulation of Prkca 1 0.43 0 0.67
193 INT257202 Protein_catabolism of Pde5a 2 0.38 0.36 0.66
194 INT165646 Positive_regulation of Transcription of Pde5a 1 0.33 1.21 0.66
195 INT208 Negative_regulation of Positive_regulation of Pde5a 3 0.17 2.02 0.65
196 INT89870 Localization of Myh6 1 0.26 0 0.65
197 INT61622 Positive_regulation of Transcription of IFNG 1 0.26 0.29 0.63
198 INT56231 Regulation of Positive_regulation of Ifng 1 0.39 0.33 0.62
199 INT116247 Positive_regulation of Localization of Adm 1 0.04 0.17 0.62
200 INT224102 Negative_regulation of Localization of Adrbk1 1 0.19 0.44 0.61
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