GO:0002027

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Name regulation of heart rate
Categary Process
Go Slim No
Go Link GO:0002027
Unique Molecular Interactions 852
Total Molecular Interactions 1335
Total Single Events 21637
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of heart rate. They are ordered first by their pain relevance and then by number of times they were reported for regulation of heart rate. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
9 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
10 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
11 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
12 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
13 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
14 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
15 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
16 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
17 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
18 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
19 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
20 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
21 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
22 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
23 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
24 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
25 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
26 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
27 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
28 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
29 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
30 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
31 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
32 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
33 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
34 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
35 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
36 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
37 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
38 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
39 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
40 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
41 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
42 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
43 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
44 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
45 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
46 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
47 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
48 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
49 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
50 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
51 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
52 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
53 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
54 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
55 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
56 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
57 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
58 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
59 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
60 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
61 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
62 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
63 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
64 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
65 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
66 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
67 INT42928 Penk Negative_regulation of Localization of Oxt 2 0.03 0 1.57
68 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
69 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
70 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
71 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
72 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
73 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
74 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
75 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
76 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
77 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
78 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
79 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
80 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
81 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
82 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
83 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
84 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
85 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
86 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
87 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
88 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
89 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
90 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
91 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
92 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
93 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
94 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
95 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
96 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
97 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
98 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
99 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
100 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
101 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
102 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
103 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
104 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
105 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
106 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
107 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
108 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
109 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
110 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
111 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
112 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
113 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
114 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
115 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
116 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
117 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
118 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
119 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
120 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
121 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
122 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
123 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
124 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
125 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
126 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
127 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
128 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
129 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
130 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
131 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
132 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
133 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
134 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
135 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
136 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
137 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
138 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
139 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
140 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
141 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
142 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
143 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
144 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
145 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
146 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
147 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
148 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
149 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
150 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
151 INT137441 Ngf Negative_regulation of Sema3a 1 0.46 2.07 1.01
152 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
153 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
154 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
155 INT334537 Sema3a Negative_regulation of Gene_expression of Plxna1 1 0.08 3.76 1
156 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
157 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
158 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
159 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
160 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
161 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
162 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96
163 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
164 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
165 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
166 INT51543 Positive_regulation of Binding of Oxt and Penk 1 0.56 0.05 0.94
167 INT12373 SCN5A Negative_regulation of Cpe 1 0.00 0 0.94
168 INT51544 Binding of Oxt and Penk 1 0.54 0.05 0.94
169 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94
170 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
171 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
172 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
173 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93
174 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 0.19 0 0.91
175 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
176 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
177 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
178 INT53153 fut10 Positive_regulation of Gene_expression of Calca 1 0.01 0 0.88
179 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
180 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
181 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
182 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
183 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86
184 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
185 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
186 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
187 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
188 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
189 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84
190 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
191 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
192 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
193 INT73032 Cck Negative_regulation of Localization of Oxt 1 0.44 0 0.82
194 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
195 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
196 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
197 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
198 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
199 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
200 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of heart rate. They are ordered first by their pain relevance and then by number of times they were reported in regulation of heart rate. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT3579 Localization of Oxt 555 0.81 43.35 292.44
8 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
9 INT626 Localization of CALCA 289 0.81 125.39 221.15
10 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
11 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
12 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
13 INT2541 Binding of Calca 200 0.48 67.14 134.62
14 INT5008 Localization of Calca 204 0.81 80.35 125.16
15 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
16 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
17 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
18 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
19 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
20 INT2893 Localization of Oxt 219 0.80 28.96 79.43
21 INT451 Regulation of Oxt 142 0.62 22.07 69.42
22 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
23 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
24 INT6761 Binding of CALCA 100 0.48 26.71 62.05
25 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
26 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
27 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
28 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
29 INT4891 Transcription of Calca 81 0.72 35.27 53.75
30 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
31 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
32 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
33 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3
34 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
35 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
36 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
37 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79
38 INT13501 Binding of Drd2 65 0.48 23.76 35.6
39 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
40 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
41 INT3117 Regulation of Oxt 103 0.61 17.93 32.28
42 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
43 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
44 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
45 INT22499 Regulation of Calca 42 0.62 17.32 28.02
46 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
47 INT12484 Binding of Drd2 45 0.48 15.17 24.72
48 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4
49 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
50 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73
51 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
52 INT2894 Negative_regulation of Localization of Oxt 43 0.58 4.59 20.85
53 INT49774 Binding of DRD2 48 0.48 17.42 20.73
54 INT5533 Binding of Oxt 43 0.48 8.69 18.35
55 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88
56 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
57 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
58 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
59 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
60 INT10340 Regulation of Localization of Oxt 30 0.60 2.55 14.3
61 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
62 INT17974 Positive_regulation of Localization of Oxt 34 0.69 4.45 12.9
63 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
64 INT26217 Binding of Calca 22 0.48 5.22 12.57
65 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
66 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
67 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
68 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
69 INT3546 Binding of Oxt 54 0.48 9.75 10.81
70 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
71 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
72 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
73 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
74 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1
75 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
76 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
77 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
78 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
79 INT26815 Regulation of OXT 15 0.46 5.38 8.31
80 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
81 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
82 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
83 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3
84 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
85 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
86 INT19302 Localization of OXT 31 0.79 3.39 6.92
87 INT2838 Positive_regulation of Gene_expression of Oxt 27 0.67 6.25 6.83
88 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55
89 INT24460 Localization of Drd2 12 0.73 2.96 6.46
90 INT38563 Negative_regulation of Gene_expression of Oxt 18 0.56 2.51 6.23
91 INT86772 Localization of Drd2 14 0.80 1.93 6.17
92 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06
93 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93
94 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
95 INT6681 Positive_regulation of Gene_expression of Drd2 10 0.65 1.78 5.78
96 INT86982 Transcription of Calca 9 0.69 2.98 5.74
97 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
98 INT23598 Binding of SCN5A 32 0.40 16 5.35
99 INT30209 Localization of SCN5A 24 0.72 7.95 5.35
100 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
101 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19
102 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11
103 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
104 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
105 INT14125 Positive_regulation of Positive_regulation of Drd2 3 0.35 0.85 4.78
106 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
107 INT58097 Transcription of Oxt 18 0.69 1.62 4.6
108 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
109 INT71676 Transcription of DRD2 5 0.69 1.19 4.47
110 INT36007 Negative_regulation of Binding of Drd2 7 0.57 3.22 4.36
111 INT13741 Positive_regulation of Positive_regulation of Oxt 13 0.56 0.44 4.29
112 INT153189 Gene_expression of Sema3a 19 0.75 14.37 4.21
113 INT10849 Negative_regulation of OXT 14 0.48 2.51 4.19
114 INT51540 Positive_regulation of Negative_regulation of Oxt 3 0.47 1.19 4.1
115 INT19300 Positive_regulation of OXT 34 0.43 4.43 4.07
116 INT36772 Positive_regulation of Positive_regulation of Oxt 11 0.69 1.73 3.94
117 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
118 INT52184 Gene_expression of Sema3a 8 0.55 3.97 3.72
119 INT74632 Transcription of Oxt 11 0.64 3.93 3.56
120 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47
121 INT102209 Negative_regulation of Gene_expression of Drd2 5 0.59 0.46 3.17
122 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
123 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
124 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
125 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
126 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
127 INT10854 Gene_expression of OXT 13 0.66 3.88 2.74
128 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
129 INT22161 Regulation of Gene_expression of Oxt 10 0.52 3.96 2.59
130 INT108468 Negative_regulation of Gene_expression of Drd2 3 0.41 0.67 2.58
131 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
132 INT26813 Negative_regulation of Localization of OXT 4 0.57 0.72 2.45
133 INT103881 Positive_regulation of Binding of DRD2 4 0.69 2.01 2.18
134 INT196176 Gene_expression of SEMA3A 3 0.75 4.75 2.17
135 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
136 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
137 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
138 INT25411 Positive_regulation of Positive_regulation of Drd2 2 0.48 0.5 1.98
139 INT26281 Negative_regulation of Negative_regulation of Oxt 5 0.43 0.31 1.91
140 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
141 INT127250 Positive_regulation of Positive_regulation of SCN5A 3 0.38 1.71 1.86
142 INT153190 Negative_regulation of Sema3a 7 0.56 7.94 1.76
143 INT74633 Positive_regulation of Negative_regulation of Oxt 1 0.40 0.85 1.74
144 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7
145 INT153762 Positive_regulation of Gene_expression of Sema3a 6 0.49 4.56 1.65
146 INT186144 Positive_regulation of Transcription of Oxt 3 0.29 2.07 1.65
147 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
148 INT38648 Regulation of Positive_regulation of Oxt 2 0.37 0.5 1.61
149 INT110136 Positive_regulation of Transcription of Oxt 10 0.39 0.48 1.57
150 INT2153 Negative_regulation of Positive_regulation of Oxt 9 0.42 1.14 1.52
151 INT72647 Positive_regulation of Gene_expression of Sema3a 3 0.40 1.98 1.52
152 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
153 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
154 INT75062 Regulation of Transcription of Drd2 1 0.51 0 1.41
155 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
156 INT7139 Regulation of Regulation of Oxt 3 0.44 0.09 1.34
157 INT143451 Negative_regulation of Gene_expression of Scn5a 2 0.43 4.63 1.34
158 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33
159 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
160 INT41470 Protein_catabolism of Oxt 2 0.85 0.31 1.27
161 INT109272 Negative_regulation of Binding of DRD2 2 0.36 0.76 1.26
162 INT92848 Gene_expression of Scn5a 3 0.73 0.23 1.25
163 INT15663 Regulation of Transcription of Drd2 2 0.26 0.1 1.25
164 INT28645 Negative_regulation of Regulation of Oxt 3 0.23 0.35 1.24
165 INT77216 Localization of DRD2 3 0.75 0 1.19
166 INT33861 Negative_regulation of Binding of Oxt 6 0.42 0.6 1.14
167 INT72822 Negative_regulation of Gene_expression of Oxt 6 0.41 2.48 1.12
168 INT265696 Negative_regulation of Transcription of Oxt 2 0.39 0.57 1.11
169 INT29825 Positive_regulation of Regulation of Oxt 1 0.49 0 1.05
170 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
171 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
172 INT93296 Gene_expression of Pmch 6 0.64 0.48 1
173 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99
174 INT19304 Positive_regulation of Localization of OXT 2 0.15 1 0.95
175 INT44841 Positive_regulation of Regulation of Oxt 1 0.50 0 0.9
176 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88
177 INT36773 Regulation of Positive_regulation of Oxt 3 0.44 0.15 0.86
178 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
179 INT11086 Regulation of Positive_regulation of Drd2 2 0.45 1.22 0.84
180 INT97673 Protein_catabolism of Calca 1 0.50 0.15 0.82
181 INT13692 Negative_regulation of Positive_regulation of Drd2 1 0.01 0 0.79
182 INT103879 Regulation of Binding of DRD2 1 0.23 0.13 0.79
183 INT16434 Regulation of Positive_regulation of Drd2 1 0.30 0 0.78
184 INT22421 Regulation of Regulation of Oxt 3 0.21 1.51 0.76
185 INT28278 Positive_regulation of Binding of Oxt 2 0.43 0.75 0.76
186 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72
187 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71
188 INT12885 Negative_regulation of Binding of Drd2 2 0.53 0.26 0.71
189 INT326603 Regulation of Positive_regulation of DRD2 1 0.44 0.8 0.69
190 INT15662 Positive_regulation of Transcription of Drd2 3 0.39 0 0.68
191 INT88815 Regulation of Negative_regulation of Oxt 1 0.07 0.09 0.68
192 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65
193 INT184840 Positive_regulation of Transcription of Drd2 2 0.35 1.03 0.65
194 INT89870 Localization of Myh6 1 0.26 0 0.65
195 INT72911 Positive_regulation of Negative_regulation of Calca 1 0.43 0.07 0.63
196 INT116175 Negative_regulation of Gene_expression of Sema3a 1 0.30 0.67 0.63
197 INT33281 Negative_regulation of Regulation of Oxt 1 0.04 0 0.62
198 INT89067 Regulation of Gene_expression of Sema3a 2 0.31 0.84 0.61
199 INT134304 Positive_regulation of Sema3a 1 0.50 1.23 0.59
200 INT72648 Localization of Sema3a 1 0.28 0.38 0.58
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