GO:0002034

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Name regulation of blood vessel size by renin-angiotensin
Categary Process
Go Slim No
Go Link GO:0002034
Unique Molecular Interactions 96
Total Molecular Interactions 126
Total Single Events 984
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of blood vessel size by renin-angiotensin. They are ordered first by their pain relevance and then by number of times they were reported for regulation of blood vessel size by renin-angiotensin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
2 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
3 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
4 INT16488 Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
5 INT16491 Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
6 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
7 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
8 INT16493 Positive_regulation of Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
9 INT16489 Positive_regulation of Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
10 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
11 INT99736 Binding of PLG and Serpinf2 1 0.01 0.73 0.55
12 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
13 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
14 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52
15 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
16 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
17 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
18 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
19 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
20 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
21 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4
22 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
23 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
24 INT99738 Binding of F13A1 and Serpinf2 1 0.00 0.49 0.37
25 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
26 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
27 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
28 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28
29 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
30 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
31 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
32 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
33 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
34 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
35 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
36 INT99731 Binding of Serpinf2 and Ppp1r1a 1 0.00 0.24 0.19
37 INT99734 Binding of SERPINE1 and Serpinf2 1 0.00 0.25 0.19
38 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
39 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
40 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
41 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
42 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
43 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
44 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
45 INT347071 Negative_regulation of REN Negative_regulation of Positive_regulation of AGT 1 0.35 0.44 0.14
46 INT34430 AGT Positive_regulation of Localization of POMC 1 0.30 0.31 0.14
47 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14
48 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
49 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
50 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13
51 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
52 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
53 INT99737 Serpinf2 Negative_regulation of Localization of SERPINE1 1 0.00 0.24 0.12
54 INT99732 Serpinf2 Negative_regulation of PLG 1 0.01 0.24 0.12
55 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12
56 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12
57 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11
58 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
59 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
60 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1
61 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1
62 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
63 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 0.00 0 0.09
64 INT279706 Positive_regulation of AGTR1 Regulation of TRPC6 1 0.00 0 0.09
65 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08
66 INT267969 Binding of AGT and TRPV1 1 0.00 0.44 0.08
67 INT267970 Negative_regulation of Binding of AGT and TRPV1 1 0.00 0.44 0.08
68 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08
69 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
70 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 0.12 0.16 0.07
71 INT281909 Binding of AGT and AGTR1 1 0.09 0.16 0.06
72 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05
73 INT336132 Binding of AGTR1 and ANG 1 0.00 0.38 0.05
74 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04
75 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03
76 INT274285 AGT Positive_regulation of Gene_expression of VEGFA 1 0.01 0.98 0.03
77 INT351663 Binding of AGT and Agt 1 0.32 0.57 0.03
78 INT274288 AGT Positive_regulation of Gene_expression of Vegfa 1 0.07 0.98 0.03
79 INT321405 AGT Positive_regulation of MAPK8 1 0.00 0.94 0.03
80 INT274284 AGT Positive_regulation of Binding of VEGFA 1 0.01 0.99 0.03
81 INT88772 Negative_regulation of Binding of AGT and Agtrap 1 0.02 0.89 0.03
82 INT213160 AGT Positive_regulation of Gene_expression of LEP 1 0.08 1.29 0.03
83 INT35137 SPANXC Positive_regulation of Negative_regulation of SERPINF2 1 0.00 0 0
84 INT281902 Binding of AGT and AKR1A1 1 0.01 0.08 0
85 INT34763 Binding of AGT and PTGER2 1 0.04 0.24 0
86 INT265950 Clas4 Negative_regulation of Gene_expression of AGT 1 0.02 0.62 0
87 INT34764 Binding of AGT and PTGIR 1 0.08 0.24 0
88 INT333044 Positive_regulation of Binding of AGTR1 and Trpv4 1 0.48 0 0
89 INT288910 REN Regulation of Gene_expression of AGT 1 0.40 1.34 0
90 INT78634 ATM Positive_regulation of AGT 1 0.17 0.16 0
91 INT333045 Binding of AGTR1 and Gopc 1 0.05 0 0
92 INT172835 Binding of AGT and T2dm2 1 0.00 1.73 0
93 INT92824 AGT Regulation of Gene_expression of REN 1 0.05 0 0
94 INT333043 Binding of AGTR1 and Trpv4 1 0.50 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of blood vessel size by renin-angiotensin. They are ordered first by their pain relevance and then by number of times they were reported in regulation of blood vessel size by renin-angiotensin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
2 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
3 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
4 INT3962 Regulation of AGT 50 0.62 20.96 13.01
5 INT398 Localization of AGT 45 0.78 16.97 11.54
6 INT8065 Binding of AGT 54 0.48 20.54 10.85
7 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27
8 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
9 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29
10 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15
11 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
12 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
13 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
14 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06
15 INT16391 Regulation of Serpinf2 5 0.03 4.22 1.82
16 INT182505 Positive_regulation of Gene_expression of AGTR1 12 0.65 13.18 1.77
17 INT14405 Gene_expression of SERPINF2 14 0.65 3 1.64
18 INT182514 Binding of AGTR1 18 0.47 13.35 1.48
19 INT14404 Negative_regulation of SERPINF2 11 0.47 3.15 1.47
20 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
21 INT182511 Regulation of AGTR1 7 0.44 8.25 1.4
22 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
23 INT11241 Transcription of AGT 4 0.52 1.83 1.27
24 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
25 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
26 INT16393 Gene_expression of Serpinf2 4 0.08 3.39 1.09
27 INT5643 Positive_regulation of SERPINF2 3 0.35 0.94 1.09
28 INT101841 Localization of SERPINF2 4 0.68 1.27 1.01
29 INT182512 Positive_regulation of Positive_regulation of AGTR1 5 0.47 4.88 0.97
30 INT16479 Positive_regulation of Serpinf2 2 0.05 1.2 0.9
31 INT73030 Regulation of SERPINF2 10 0.39 5.69 0.8
32 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
33 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
34 INT102894 Localization of AGTR1 5 0.73 1.75 0.74
35 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
36 INT23348 Negative_regulation of Serpinf2 8 0.38 3.02 0.65
37 INT16392 Protein_catabolism of Serpinf2 1 0.03 1.38 0.64
38 INT142625 Negative_regulation of Localization of SERPINF2 1 0.31 0.16 0.59
39 INT267971 Regulation of Localization of AGTR1 1 0.16 1.46 0.57
40 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
41 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
42 INT107385 Regulation of Negative_regulation of AGTR1 2 0.15 1.26 0.42
43 INT182507 Negative_regulation of Gene_expression of AGTR1 1 0.40 1.13 0.4
44 INT330125 Transcription of AGTR1 1 0.52 1.29 0.39
45 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
46 INT102889 Positive_regulation of Localization of AGTR1 3 0.38 0.43 0.34
47 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
48 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
49 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
50 INT263255 Negative_regulation of Negative_regulation of AGTR1 2 0.30 2.88 0.25
51 INT288916 Negative_regulation of Positive_regulation of AGTR1 2 0.44 1.2 0.13
52 INT79414 Binding of Serpinf2 1 0.24 0.35 0.13
53 INT214619 Positive_regulation of Negative_regulation of AGT 1 0.04 0.98 0.13
54 INT28108 Protein_catabolism of SERPINF2 1 0.96 0 0.1
55 INT242222 Positive_regulation of Negative_regulation of AGTR1 1 0.35 1.77 0.1
56 INT50849 Negative_regulation of Regulation of AGT 2 0.42 1.26 0.08
57 INT288915 Regulation of Positive_regulation of AGT 1 0.41 0.82 0.08
58 INT24661 Positive_regulation of Gene_expression of SERPINF2 1 0.21 0.7 0.08
59 INT333041 Regulation of Positive_regulation of AGTR1 1 0.44 0 0.07
60 INT179198 Regulation of Gene_expression of AGTR1 2 0.25 2.04 0.04
61 INT35145 Negative_regulation of Gene_expression of SERPINF2 2 0.41 0 0
62 INT288912 Protein_catabolism of AGTR1 1 0.66 0.29 0
63 INT296133 Positive_regulation of Regulation of SERPINF2 1 0.02 0.76 0
64 INT333040 Regulation of Binding of AGTR1 1 0.44 0 0
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