GO:0002039

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Name p53 binding
Categary Function
Go Slim No
Go Link GO:0002039
Unique Molecular Interactions 661
Total Molecular Interactions 894
Total Single Events 7244
Pain Genes Associated 55

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for p53 binding. They are ordered first by their pain relevance and then by number of times they were reported for p53 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
3 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
4 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
5 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
6 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
7 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
8 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
9 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1
10 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
11 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
12 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
13 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
14 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
15 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
16 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
17 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
18 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
19 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
20 INT172982 Binding of MUC1 and MUC4 1 0.30 2.46 0.78
21 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
22 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
23 INT40134 Binding of Pomc and Noc2l 1 0.01 0.08 0.7
24 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
25 INT132154 PSG7 Positive_regulation of Localization of MUC1 1 0.00 0 0.65
26 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
27 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
28 INT139189 Binding of Daxx and Fadd 1 0.03 0.27 0.57
29 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
30 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
31 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
32 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
33 INT324816 Hspd1 Positive_regulation of Gene_expression of Ik 1 0.00 1.59 0.5
34 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48
35 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
36 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
37 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
38 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
39 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
40 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
41 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
42 INT302824 Mapkapk5 Positive_regulation of Phosphorylation of Hspb2 1 0.11 0.64 0.4
43 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
44 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
45 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
46 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
47 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
48 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
49 INT291394 Gene_expression of HTT Negative_regulation of Gene_expression of Slc1a2 1 0.11 0.96 0.34
50 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
51 INT132174 PSG7 Positive_regulation of Gene_expression of Muc1 1 0.00 0 0.34
52 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
53 INT132169 PSG7 Positive_regulation of Muc1 1 0.00 0 0.34
54 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33
55 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
56 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
57 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
58 INT132155 PSG7 Positive_regulation of Gene_expression of MUC1 1 0.00 0 0.32
59 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
60 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
61 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
62 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
63 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
64 INT324830 Hspd1 Positive_regulation of IFNA1 1 0.04 0.46 0.3
65 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
66 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
67 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
68 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
69 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29
70 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
71 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
72 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
73 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
74 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
75 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
76 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
77 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
78 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
79 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
80 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
81 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
82 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
83 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
84 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
85 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
86 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
87 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
88 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
89 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
90 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
91 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
92 INT35178 Binding of STT3A and PSME3 1 0.01 0.38 0.25
93 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
94 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
95 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
96 INT111909 Binding of HSPD1 and CCT4 1 0.29 0.48 0.25
97 INT111908 Binding of HSPD1 and AP4B1 1 0.03 0.48 0.25
98 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
99 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
100 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
101 INT276952 Tlr2 Positive_regulation of Localization of Hspd1 1 0.25 0.16 0.24
102 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
103 INT324835 Hspd1 Positive_regulation of Gene_expression of IFNA1 1 0.15 0.31 0.23
104 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
105 INT147590 Binding of Muc1 and Mag 1 0.26 3.29 0.23
106 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
107 INT190827 KCNA1 Regulation of Localization of MUC1 1 0.05 0.08 0.22
108 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
109 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
110 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
111 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
112 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
113 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
114 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
115 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21
116 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
117 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
118 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
119 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
120 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
121 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
122 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
123 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19
124 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
125 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
126 INT276946 Hspd1 Positive_regulation of Tlr2 2 0.37 1.01 0.17
127 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
128 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17
129 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
130 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
131 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
132 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
133 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
134 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
135 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
136 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
137 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
138 INT231765 Binding of HSPD1 and TLR4 1 0.13 1.94 0.16
139 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
140 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
141 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
142 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
143 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15
144 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
145 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
146 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
147 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
148 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
149 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
150 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
151 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
152 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
153 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
154 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
155 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
156 INT185455 MUC1 Negative_regulation of Timp1 1 0.06 0.84 0.13
157 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
158 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
159 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
160 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
161 INT324804 Binding of Hspd1 and Tlr4 1 0.14 0.36 0.13
162 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
163 INT276950 Hspd1 Positive_regulation of Positive_regulation of Tlr2 1 0.22 1.25 0.13
164 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
165 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
166 INT185416 MUC1 Negative_regulation of TIMP1 1 0.18 0.84 0.13
167 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
168 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
169 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
170 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
171 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
172 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12
173 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
174 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
175 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
176 INT189559 STK11 Positive_regulation of SNRK 1 0.03 0.36 0.11
177 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
178 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
179 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
180 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
181 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
182 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
183 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
184 INT192358 CRP Regulation of Positive_regulation of HSPD1 1 0.15 2.46 0.1
185 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
186 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
187 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
188 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
189 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
190 INT317392 Negative_regulation of Binding of Stk11 and Amp1 1 0.05 0.34 0.1
191 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
192 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
193 INT192352 CRP Regulation of HSPD1 1 0.15 2.46 0.1
194 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
195 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
196 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
197 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
198 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
199 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
200 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for p53 binding. They are ordered first by their pain relevance and then by number of times they were reported in p53 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19
3 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
4 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
5 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
6 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
7 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
8 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
9 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
10 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
11 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
12 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
13 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
14 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
15 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
16 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
17 INT49802 Localization of MUC1 75 0.81 44.74 8.87
18 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
19 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
20 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
21 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
22 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
23 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
24 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
25 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
26 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
27 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
28 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
29 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
30 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
31 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
32 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
33 INT60585 Regulation of TP53 59 0.59 54.55 5.21
34 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
35 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
36 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
37 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
38 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56
39 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
40 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
41 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
42 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
43 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
44 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75
45 INT73981 Gene_expression of Hspd1 18 0.75 5.69 3.72
46 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69
47 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
48 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
49 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
50 INT12844 Binding of TP63 15 0.47 10.57 3.38
51 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
52 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
53 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
54 INT40128 Binding of Noc2l 7 0.27 0.67 3.03
55 INT8103 Binding of TP53 46 0.44 40.2 2.96
56 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
57 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
58 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
59 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
60 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
61 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
62 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
63 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
64 INT202341 Gene_expression of Mapkapk5 3 0.46 3.67 2.43
65 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
66 INT9473 Binding of MUC1 66 0.48 46.77 2.36
67 INT55952 Transcription of TP53 16 0.61 12.14 2.36
68 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
69 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
70 INT173005 Transcription of MUC1 11 0.63 10.15 2.24
71 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
72 INT123705 Gene_expression of SMARCB1 40 0.73 19.47 2.2
73 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
74 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
75 INT262317 Binding of TAF9 7 0.31 9.67 2.15
76 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
77 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
78 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06
79 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
80 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
81 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
82 INT65855 Localization of TP53 18 0.76 17.08 1.89
83 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
84 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
85 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
86 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
87 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
88 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
89 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
90 INT210455 Gene_expression of Noc2l 3 0.33 1.01 1.58
91 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
92 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
93 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
94 INT302790 Positive_regulation of Mapkapk5 1 0.25 2.6 1.55
95 INT132163 Positive_regulation of Localization of MUC1 9 0.19 8.96 1.54
96 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
97 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
98 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
99 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
100 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
101 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
102 INT172953 Binding of Trp53 33 0.37 20.76 1.41
103 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
104 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
105 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
106 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
107 INT53775 Gene_expression of Hspd1 21 0.78 31.25 1.38
108 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
109 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
110 INT145221 Binding of Tp53 10 0.37 8.59 1.37
111 INT319724 Binding of Crebbp 1 0.16 4.19 1.34
112 INT53776 Positive_regulation of Hspd1 17 0.70 10.64 1.23
113 INT73176 Positive_regulation of Hspd1 5 0.35 3.96 1.22
114 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
115 INT49804 Negative_regulation of Localization of MUC1 7 0.59 5.84 1.19
116 INT174156 Localization of Trp53 16 0.72 13.52 1.18
117 INT112891 Regulation of Gene_expression of HSPD1 2 0.43 3.98 1.17
118 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
119 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
120 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
121 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
122 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
123 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
124 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
125 INT108551 Gene_expression of MAPKAPK5 1 0.15 1.23 1.1
126 INT108553 Negative_regulation of Gene_expression of MAPKAPK5 1 0.09 1.23 1.1
127 INT108552 Regulation of MAPKAPK5 1 0.10 1.19 1.08
128 INT108997 Localization of Htt 28 0.77 3.76 1.07
129 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
130 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
131 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
132 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
133 INT114673 Regulation of Gene_expression of Mdm2 1 0.62 0.23 1.02
134 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
135 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99
136 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
137 INT156326 Positive_regulation of SMARCB1 20 0.67 8.77 0.97
138 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
139 INT117880 Negative_regulation of Crebbp 3 0.38 0.69 0.94
140 INT114922 Phosphorylation of Crebbp 2 0.21 0.92 0.94
141 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
142 INT133608 Regulation of Daxx 1 0.16 0.28 0.93
143 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
144 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
145 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
146 INT68692 Regulation of HTT 8 0.60 4.06 0.89
147 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
148 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
149 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
150 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
151 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
152 INT107161 Positive_regulation of MAPKAPK5 2 0.16 1.15 0.82
153 INT302768 Regulation of Mapkapk5 1 0.24 1.6 0.82
154 INT89290 Regulation of MUC1 19 0.45 10.4 0.81
155 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
156 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
157 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
158 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
159 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
160 INT302792 Transcription of Mapkapk5 1 0.38 1.37 0.8
161 INT173003 Negative_regulation of Gene_expression of MUC1 15 0.57 10.27 0.79
162 INT282916 Positive_regulation of Transcription of MUC1 2 0.45 0.47 0.79
163 INT121334 Binding of HTT 11 0.47 6.66 0.78
164 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
165 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
166 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
167 INT302771 Negative_regulation of Mapkapk5 1 0.23 1.46 0.77
168 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
169 INT44293 Regulation of TP63 6 0.24 2.88 0.76
170 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
171 INT114956 Gene_expression of CREBBP 5 0.31 1.56 0.75
172 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
173 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
174 INT144880 Negative_regulation of DAXX 4 0.23 2.15 0.73
175 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
176 INT188347 Localization of Hspd1 2 0.41 4.53 0.71
177 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
178 INT133603 Gene_expression of Daxx 1 0.28 0.27 0.7
179 INT133606 Regulation of Gene_expression of Daxx 1 0.16 0.27 0.7
180 INT242137 Negative_regulation of Positive_regulation of Gsk3b 7 0.39 2.99 0.67
181 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
182 INT132164 Gene_expression of Muc1 4 0.71 4.15 0.67
183 INT75043 Binding of Msx1 6 0.35 2.36 0.65
184 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
185 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
186 INT116838 Regulation of Gene_expression of Hspd1 1 0.18 0.19 0.62
187 INT123704 Binding of SMARCB1 12 0.36 5.49 0.61
188 INT114955 Positive_regulation of Gene_expression of CREBBP 2 0.23 0.24 0.61
189 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
190 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
191 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
192 INT53774 Positive_regulation of Gene_expression of Hspd1 7 0.70 6.99 0.6
193 INT204006 Negative_regulation of Localization of Gsk3b 6 0.40 1.66 0.6
194 INT121336 Positive_regulation of HTT 10 0.45 10.88 0.59
195 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
196 INT129771 Regulation of SMARCB1 5 0.58 8.92 0.58
197 INT230679 Positive_regulation of Binding of Gsk3b 3 0.42 1.42 0.58
198 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
199 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
200 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
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