GO:0002040

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Name sprouting angiogenesis
Categary Process
Go Slim No
Go Link GO:0002040
Unique Molecular Interactions 202
Total Molecular Interactions 301
Total Single Events 1580
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sprouting angiogenesis. They are ordered first by their pain relevance and then by number of times they were reported for sprouting angiogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
3 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
4 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
5 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
6 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
7 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
8 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
9 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
10 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
11 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
12 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
13 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
14 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
15 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
16 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
17 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
18 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
19 INT345012 GSN Regulation of CCBE1 1 0.00 0.82 0.36
20 INT345009 DBP Regulation of CCBE1 1 0.00 0.81 0.36
21 INT165305 CSF2 Positive_regulation of Localization of CCBE1 1 0.06 1.34 0.35
22 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
23 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34
24 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
25 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33
26 INT119333 Binding of Ramp2 and Positive_regulation of Gpr182 1 0.18 0.13 0.3
27 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
28 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
29 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
30 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
31 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
32 INT194404 Binding of RAMP2 and DCLK3 1 0.07 0 0.22
33 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
34 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
35 INT260827 Binding of Flt1 and Pgf 1 0.27 0.6 0.2
36 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19
37 INT197097 IL1B Regulation of FLT4 1 0.03 0.66 0.19
38 INT197098 TNF Regulation of FLT4 1 0.14 0.66 0.19
39 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
40 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
41 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
42 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
43 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
44 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
45 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
46 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
47 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
48 INT260834 Negative_regulation of Binding of VEGFA and Flt1 1 0.15 0.5 0.13
49 INT230760 VEGFA Positive_regulation of Flt1 1 0.03 0.96 0.12
50 INT289660 Tnfrsf1a Negative_regulation of Transcription of Flt4 1 0.03 0.62 0.12
51 INT289657 Tnfrsf1a Negative_regulation of Gene_expression of Flt4 1 0.03 0.63 0.12
52 INT236401 Binding of Flt1 and Mthfs 1 0.01 0.28 0.11
53 INT236403 Binding of Flt1 and Negative_regulation of Gene_expression of VEGFA 1 0.04 0.3 0.11
54 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
55 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
56 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1
57 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
58 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
59 INT318210 MUC5AC Negative_regulation of Phosphorylation of Flt1 1 0.07 0.98 0.09
60 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
61 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
62 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
63 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
64 INT320785 Binding of Flt1 and Kdr 1 0.15 0.67 0.08
65 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07
66 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
67 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
68 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
69 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
70 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
71 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
72 INT320795 Flt1 Negative_regulation of VEGFA 1 0.29 0.29 0.06
73 INT298699 Kdr Regulation of Tek 1 0.11 0.28 0.06
74 INT298701 Manea Regulation of Tek 1 0.03 0.28 0.06
75 INT203732 Thbs1 Regulation of Gene_expression of Ppara 1 0.33 0.94 0.05
76 INT345371 Binding of Flt4 and Kdr 1 0.10 1.12 0.05
77 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
78 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
79 INT292094 Binding of FLT4 and TXK 1 0.02 1.53 0.04
80 INT292093 Negative_regulation of Binding of FLT4 and TXK 1 0.03 1.53 0.04
81 INT178501 Angpt1 Positive_regulation of Tek 1 0.06 0.78 0.04
82 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
83 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03
84 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
85 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
86 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
87 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
88 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
89 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
90 INT300448 Binding of VEGFA and Flt1 3 0.10 1.93 0
91 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
92 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
93 INT329648 Flt1 Positive_regulation of Positive_regulation of VEGFA 1 0.03 0.58 0
94 INT291199 Binding of VEGFA and Angpt1 1 0.08 0.69 0
95 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
96 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
97 INT312330 Binding of Kdr and Flt1 1 0.12 0.37 0
98 INT300444 Flt1 Regulation of VEGFA 1 0.03 0.26 0
99 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
100 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
101 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
102 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
103 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
104 INT327873 Postn Regulation of Notch1 1 0.41 0 0
105 INT292088 Binding of AMELX and ANGPT1 1 0.00 0.9 0
106 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
107 INT99770 Thbs1 Regulation of PGR 1 0.01 0 0
108 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
109 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
110 INT356083 Binding of App and Notch1 1 0.02 0.2 0
111 INT51875 CCBE1 Regulation of POMC 1 0.00 1.06 0
112 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
113 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
114 INT324663 Negative_regulation of Flt1 Positive_regulation of Vash1 1 0.44 0.55 0
115 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
116 INT337262 PRB1 Negative_regulation of THBS1 1 0.18 0.61 0
117 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
118 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0
119 INT294066 ANGPT1 Positive_regulation of VEGFA 1 0.01 0.1 0
120 INT99769 Thbs1 Regulation of THBS1 1 0.00 0 0
121 INT277490 Binding of F2 and Thbs1 1 0.09 0 0
122 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
123 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
124 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
125 INT109817 Ace2 Positive_regulation of Angpt1 1 0.05 0.31 0
126 INT268524 MYC Regulation of THBS1 1 0.02 1.85 0
127 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
128 INT351679 Fut1 Negative_regulation of Gene_expression of Flt1 1 0.00 1.01 0
129 INT300437 Kdr Regulation of Gene_expression of Flt1 1 0.42 0.26 0
130 INT51876 CCBE1 Regulation of GHRH 1 0.01 1.07 0
131 INT197096 VEGFA Positive_regulation of FLT4 1 0.04 1.43 0
132 INT345374 VEGFA Positive_regulation of Flt4 1 0.01 2.95 0
133 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
134 INT197099 Negative_regulation of Binding of FLT4 and VEGFA 1 0.04 1.04 0
135 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
136 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
137 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
138 INT298702 Tek Regulation of Kdr 1 0.03 0.33 0
139 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0
140 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
141 INT300436 Flt1 Negative_regulation of Kdr 1 0.35 0.4 0
142 INT268887 Binding of ANGPT1 and Tek 1 0.10 0 0
143 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0
144 INT176096 Regulation of Binding of Angpt1 and Tek 1 0.07 0.54 0
145 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
146 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
147 INT176097 Binding of Angpt1 and Tek 1 0.06 0.48 0
148 INT277489 Binding of Thbs1 and Gopc 1 0.14 0 0
149 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
150 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0
151 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0
152 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0
153 INT51878 CCBE1 Regulation of CRH 1 0.01 1.06 0
154 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
155 INT99771 Oxtr Regulation of THBS1 1 0.01 0 0
156 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
157 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
158 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
159 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
160 INT312331 Binding of Flt1 and Pgf 1 0.08 0.31 0
161 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
162 INT51877 CCBE1 Regulation of NPY 1 0.01 1.06 0
163 INT255691 Positive_regulation of Binding of VEGFA and Flt1 1 0.02 0 0
164 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
165 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
166 INT299456 Binding of Gabpa and Notch1 1 0.21 0.09 0
167 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
168 INT298704 Tek Regulation of Manea 1 0.02 0.33 0
169 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0
170 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0
171 INT200558 Flt1 Regulation of Aliq1 1 0.02 0.97 0
172 INT268511 MIR19B1 Regulation of THBS1 1 0.20 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sprouting angiogenesis. They are ordered first by their pain relevance and then by number of times they were reported in sprouting angiogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
2 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
3 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
4 INT43707 Positive_regulation of CCBE1 11 0.07 8.22 4.86
5 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
6 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
7 INT102452 Gene_expression of RAMP2 6 0.69 7.11 3.77
8 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
9 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
10 INT22949 Gene_expression of CCBE1 8 0.19 4.27 3.25
11 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
12 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
13 INT31875 Regulation of CCBE1 8 0.04 4.18 2.64
14 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
15 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
16 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
17 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13
18 INT100371 Positive_regulation of Flt1 11 0.63 6.42 2.02
19 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
20 INT134628 Gene_expression of Flt4 9 0.48 7.52 1.94
21 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
22 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
23 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
24 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
25 INT255663 Binding of Flt1 11 0.32 6.92 1.64
26 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
27 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
28 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
29 INT123926 Gene_expression of Angpt1 28 0.54 21.74 1.47
30 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
31 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37
32 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37
33 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
34 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
35 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
36 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
37 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
38 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
39 INT11553 Negative_regulation of CCBE1 3 0.03 1.1 1.25
40 INT150805 Localization of THBS1 4 0.46 2.88 1.23
41 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
42 INT109078 Positive_regulation of ANGPT1 7 0.22 3.08 1.21
43 INT110780 Localization of Notch1 2 0.06 0.47 1.19
44 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
45 INT134627 Positive_regulation of Gene_expression of Flt1 9 0.49 7.16 1.12
46 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
47 INT203729 Binding of Thbs1 1 0.27 3.83 1.1
48 INT130928 Positive_regulation of Gene_expression of Thbs1 7 0.62 5.62 1.08
49 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
50 INT6833 Binding of Notch1 4 0.36 0.05 0.94
51 INT197105 Negative_regulation of FLT4 13 0.42 11.48 0.92
52 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91
53 INT109080 Negative_regulation of ANGPT1 8 0.14 3.17 0.82
54 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
55 INT130363 Localization of Thbs1 9 0.75 4.99 0.76
56 INT119331 Gene_expression of Ramp2 2 0.60 0.19 0.75
57 INT289649 Regulation of Gene_expression of Flt4 1 0.21 0.66 0.72
58 INT123927 Positive_regulation of Gene_expression of Angpt1 12 0.48 10.18 0.71
59 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
60 INT100374 Positive_regulation of Positive_regulation of Flt1 1 0.09 0.99 0.62
61 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
62 INT289655 Regulation of Flt4 1 0.29 0.63 0.6
63 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
64 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59
65 INT346182 Positive_regulation of Gene_expression of RAMP2 1 0.14 1.51 0.58
66 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57
67 INT181790 Gene_expression of FLT4 13 0.72 11.73 0.56
68 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
69 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
70 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
71 INT150808 Negative_regulation of Localization of THBS1 1 0.25 0.5 0.53
72 INT18475 Protein_catabolism of CCBE1 1 0.01 0 0.53
73 INT134629 Positive_regulation of Gene_expression of Flt4 3 0.32 2.13 0.52
74 INT255665 Localization of Flt1 5 0.63 7.65 0.51
75 INT109390 Regulation of Gene_expression of Flt1 4 0.41 4.08 0.51
76 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
77 INT43898 Regulation of Gene_expression of CCBE1 1 0.01 0.17 0.5
78 INT119326 Positive_regulation of Ramp2 1 0.42 0.2 0.48
79 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47
80 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
81 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
82 INT96909 Regulation of Angpt1 2 0.17 0.37 0.43
83 INT203728 Regulation of Binding of Thbs1 1 0.33 2.76 0.42
84 INT346192 Negative_regulation of RAMP2 1 0.12 0.92 0.42
85 INT203726 Regulation of Thbs1 2 0.33 1.41 0.41
86 INT176085 Regulation of Tek 6 0.37 3.36 0.4
87 INT255662 Regulation of Positive_regulation of Flt1 1 0.29 2.57 0.4
88 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39
89 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
90 INT196002 Positive_regulation of Flt4 4 0.22 3.51 0.37
91 INT130927 Negative_regulation of Thbs1 19 0.59 3.72 0.36
92 INT176079 Positive_regulation of Tek 6 0.41 3.15 0.36
93 INT254367 Transcription of TEK 1 0.14 1.08 0.36
94 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
95 INT165306 Localization of CCBE1 1 0.09 1.34 0.35
96 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
97 INT181921 Binding of TEK 2 0.09 1.88 0.32
98 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31
99 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
100 INT119325 Binding of Ramp2 1 0.33 0.12 0.29
101 INT200550 Regulation of Flt1 7 0.45 5.22 0.27
102 INT196006 Regulation of FLT4 2 0.25 2.24 0.27
103 INT236397 Binding of Flt1 5 0.33 1.91 0.24
104 INT96908 Protein_catabolism of Angpt1 1 0.41 0.26 0.24
105 INT220396 Negative_regulation of Angpt1 4 0.26 1.64 0.23
106 INT130368 Transcription of Thbs1 2 0.69 1.39 0.23
107 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
108 INT130360 Positive_regulation of Transcription of Thbs1 1 0.46 1.41 0.23
109 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
110 INT40062 Binding of CCBE1 1 0.03 1.3 0.21
111 INT222635 Gene_expression of Thbs1 4 0.39 15.2 0.2
112 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
113 INT181791 Positive_regulation of Gene_expression of ANGPT1 1 0.29 1.27 0.2
114 INT181788 Positive_regulation of Gene_expression of TEK 1 0.27 1.26 0.2
115 INT193945 Binding of Notch1 7 0.15 1.28 0.19
116 INT324639 Transcription of Flt1 5 0.45 2.67 0.19
117 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
118 INT178481 Binding of Tek 2 0.28 1.55 0.19
119 INT178504 Positive_regulation of Localization of THBS1 2 0.05 1.9 0.19
120 INT197104 Positive_regulation of Gene_expression of FLT4 1 0.56 3.45 0.19
121 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
122 INT176091 Regulation of Positive_regulation of Tek 1 0.37 0.22 0.18
123 INT197102 Localization of FLT4 4 0.65 2.89 0.17
124 INT231474 Binding of THBS1 4 0.34 2.04 0.16
125 INT156590 Negative_regulation of Negative_regulation of ANGPT1 1 0.10 0.33 0.16
126 INT105044 Negative_regulation of Flt1 4 0.39 2.99 0.15
127 INT348150 Binding of Thbs1 1 0.24 2.06 0.15
128 INT290923 Positive_regulation of Angpt1 3 0.48 3.62 0.14
129 INT236400 Regulation of Flt1 3 0.25 1.84 0.14
130 INT298697 Negative_regulation of Tek 2 0.35 0.85 0.14
131 INT197103 Binding of FLT4 2 0.29 3.08 0.14
132 INT297239 Positive_regulation of Gene_expression of Notch1 2 0.40 1.31 0.13
133 INT130572 Positive_regulation of Gene_expression of Flt1 2 0.46 3.24 0.13
134 INT340571 Positive_regulation of Localization of Flt1 1 0.10 0.88 0.13
135 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
136 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
137 INT316042 Negative_regulation of Gene_expression of Notch1 1 0.27 1.7 0.12
138 INT289653 Negative_regulation of Transcription of Flt4 1 0.20 0.62 0.12
139 INT289652 Transcription of Flt4 1 0.34 0.62 0.12
140 INT226281 Regulation of TEK 1 0.60 1.33 0.11
141 INT348149 Regulation of Gene_expression of Thbs1 1 0.31 1.94 0.1
142 INT354414 Localization of ANGPT1 1 0.10 0 0.1
143 INT348145 Localization of Thbs1 1 0.41 6.72 0.1
144 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
145 INT315145 Phosphorylation of Flt1 4 0.40 2.88 0.09
146 INT222603 Negative_regulation of Gene_expression of Ramp2 1 0.09 0 0.09
147 INT196007 Positive_regulation of FLT4 2 0.56 5.44 0.08
148 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
149 INT291188 Regulation of Gene_expression of Angpt1 1 0.31 1.78 0.08
150 INT291183 Negative_regulation of Angpt1 1 0.30 0.89 0.08
151 INT222588 Negative_regulation of Gene_expression of Thbs1 2 0.30 7.93 0.07
152 INT327728 Regulation of Gene_expression of Notch1 2 0.27 0.73 0.07
153 INT291195 Negative_regulation of Gene_expression of Angpt1 1 0.41 2.29 0.07
154 INT292803 Negative_regulation of Phosphorylation of Flt1 1 0.10 0.46 0.06
155 INT178495 Negative_regulation of Positive_regulation of Tek 1 0.14 1.05 0.06
156 INT200861 Negative_regulation of Binding of Tek 1 0.32 0.3 0.06
157 INT292801 Phosphorylation of Flt1 1 0.19 0.46 0.06
158 INT197101 Positive_regulation of Localization of FLT4 1 0.38 0.77 0.06
159 INT290930 Localization of Angpt1 1 0.21 0 0.06
160 INT193845 Localization of Notch1 2 0.78 0.32 0.05
161 INT320783 Binding of Flt4 2 0.26 0.98 0.05
162 INT193850 Regulation of Localization of Notch1 1 0.14 0.33 0.05
163 INT220802 Binding of LEF1 7 0.36 3.86 0.04
164 INT222624 Negative_regulation of Thbs1 2 0.30 8.42 0.04
165 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
166 INT255664 Regulation of Gene_expression of Flt1 2 0.44 1.67 0.04
167 INT289110 Localization of LEF1 2 0.32 1.19 0.04
168 INT99763 Regulation of Thbs1 2 0.23 2.08 0.04
169 INT290916 Regulation of Angpt1 2 0.31 1.01 0.04
170 INT258065 Protein_catabolism of ANGPT1 1 0.01 0.47 0.04
171 INT178484 Positive_regulation of Phosphorylation of Tek 1 0.23 0.79 0.04
172 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
173 INT291193 Binding of Angpt1 1 0.26 1.87 0.04
174 INT178486 Phosphorylation of Tek 1 0.27 0.73 0.04
175 INT348152 Positive_regulation of Localization of Thbs1 1 0.24 0.85 0.04
176 INT348157 Regulation of Transcription of Thbs1 1 0.14 0.96 0.04
177 INT348147 Transcription of Thbs1 1 0.27 0.96 0.04
178 INT200553 Negative_regulation of Gene_expression of Flt1 11 0.33 6.79 0.03
179 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
180 INT294469 Transcription of THBS1 2 0.66 0.46 0.03
181 INT231690 Negative_regulation of Binding of THBS1 1 0.16 0.37 0.03
182 INT319335 Transcription of FLT4 1 0.18 0.99 0.03
183 INT312928 Localization of Tek 1 0.31 0.66 0.03
184 INT294078 Regulation of ANGPT1 3 0.04 1.25 0
185 INT268882 Binding of ANGPT1 3 0.07 0.89 0
186 INT232397 Protein_catabolism of Notch1 3 0.64 1.56 0
187 INT265555 Transcription of Flt1 2 0.49 0.96 0
188 INT200683 Gene_expression of PTK2B 2 0.67 1.02 0
189 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
190 INT294081 Negative_regulation of Gene_expression of ANGPT1 2 0.04 0.19 0
191 INT222611 Protein_catabolism of Flt1 1 0.13 0 0
192 INT297242 Transcription of Notch1 1 0.19 0.25 0
193 INT337281 Regulation of Gene_expression of THBS1 1 0.57 0.48 0
194 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
195 INT277482 Negative_regulation of Transcription of Thbs1 1 0.43 0 0
196 INT252974 Positive_regulation of Negative_regulation of THBS1 1 0.03 0.09 0
197 INT179110 Regulation of Localization of Flt1 1 0.13 0.49 0
198 INT348156 Positive_regulation of Gene_expression of Thbs1 1 0.24 0.9 0
199 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
200 INT347528 Negative_regulation of Flt4 1 0.29 0.13 0
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