GO:0002051

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Name osteoblast fate commitment
Categary Process
Go Slim No
Go Link GO:0002051
Unique Molecular Interactions 20
Total Molecular Interactions 26
Total Single Events 185
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for osteoblast fate commitment. They are ordered first by their pain relevance and then by number of times they were reported for osteoblast fate commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26
2 INT223963 Binding of Bglap and Runx2 1 0.14 1.74 0.13
3 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13
4 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12
5 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
6 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03
7 INT319219 Bmpr2 Positive_regulation of Smad1 1 0.18 0.29 0.03
8 INT319217 Bmpr2 Positive_regulation of Gene_expression of Smad1 1 0.19 0.11 0.03
9 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0
10 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0
11 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0
12 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0
13 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0
14 INT329746 ENG Positive_regulation of SMAD1 1 0.15 0.44 0
15 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0
16 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0
17 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
18 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0
19 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for osteoblast fate commitment. They are ordered first by their pain relevance and then by number of times they were reported in osteoblast fate commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
2 INT43484 Binding of Runx2 7 0.37 3.22 0.95
3 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65
4 INT197832 Localization of MEN1 1 0.80 11.01 0.63
5 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
6 INT285501 Gene_expression of Smad1 6 0.42 3.09 0.41
7 INT311882 Negative_regulation of Smad1 1 0.25 0.99 0.39
8 INT142117 Regulation of Runx2 6 0.61 2.75 0.22
9 INT171614 Positive_regulation of Runx2 13 0.63 3.04 0.19
10 INT311891 Phosphorylation of Smad1 4 0.51 1.34 0.18
11 INT171605 Negative_regulation of Runx2 4 0.46 2.14 0.17
12 INT310174 Positive_regulation of Smad1 9 0.45 2.16 0.14
13 INT211942 Transcription of Runx2 3 0.69 2.46 0.08
14 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07
15 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06
16 INT311890 Binding of Smad1 2 0.23 0.46 0.04
17 INT311888 Negative_regulation of Phosphorylation of Smad1 1 0.25 0.48 0.03
18 INT142118 Regulation of Gene_expression of Runx2 2 0.61 2.92 0
19 INT211944 Regulation of Transcription of Runx2 1 0.34 0.32 0
20 INT329771 Positive_regulation of SMAD1 1 0.36 2.3 0
21 INT329780 Negative_regulation of Positive_regulation of SMAD1 1 0.22 0.51 0
22 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0
23 INT197843 Regulation of Localization of MEN1 1 0.45 0.24 0
24 INT197838 Transcription of MEN1 1 0.69 0.13 0
25 INT265814 Localization of Runx2 1 0.75 0.84 0
26 INT197824 Positive_regulation of Transcription of MEN1 1 0.50 0.13 0
27 INT277589 Regulation of Negative_regulation of Runx2 1 0.36 0.78 0
28 INT265813 Regulation of Binding of Runx2 1 0.27 0.19 0
29 INT171613 Positive_regulation of Positive_regulation of Runx2 1 0.01 0 0
30 INT197834 Binding of MEN1 1 0.48 3.32 0
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