GO:0002062

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Name chondrocyte differentiation
Categary Process
Go Slim No
Go Link GO:0002062
Unique Molecular Interactions 755
Total Molecular Interactions 897
Total Single Events 7845
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chondrocyte differentiation. They are ordered first by their pain relevance and then by number of times they were reported for chondrocyte differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
2 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
3 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
4 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
5 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
6 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
7 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
8 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
9 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
10 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
11 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
12 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
13 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
14 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
15 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
16 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
17 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
18 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
19 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
20 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
21 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
22 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
23 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
24 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
25 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
26 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
27 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
28 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
29 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
30 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
31 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
32 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
33 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
34 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15
35 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
36 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
37 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
38 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
39 INT134487 Positive_regulation of TGFBI Positive_regulation of Ltp 1 0.03 1.19 1.11
40 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
41 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
42 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
43 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
44 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
45 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
46 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
47 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
48 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
49 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
50 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
51 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
52 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
53 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
54 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
55 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
56 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
57 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
58 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
59 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
60 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
61 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
62 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
63 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
64 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
65 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
66 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
67 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
68 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
69 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
70 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
71 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84
72 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
73 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
74 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
75 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
76 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82
77 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
78 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
79 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
80 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
81 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
82 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
83 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
84 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
85 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
86 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
87 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
88 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
89 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
90 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
91 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
92 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
93 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
94 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
95 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
96 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
97 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
98 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
99 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
100 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
101 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
102 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
103 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72
104 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
105 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
106 INT306263 Binding of NFIB and TFAM 1 0.00 1.74 0.7
107 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
108 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
109 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
110 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
111 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
112 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
113 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
114 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
115 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65
116 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65
117 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
118 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
119 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
120 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
121 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63
122 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
123 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
124 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61
125 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
126 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
127 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61
128 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
129 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
130 INT65285 TGFBI Negative_regulation of Pc 1 0.20 0.79 0.59
131 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
132 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
133 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57
134 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
135 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55
136 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
137 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
138 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55
139 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
140 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
141 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
142 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
143 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
144 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
145 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53
146 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
147 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
148 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
149 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
150 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
151 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
152 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
153 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
154 INT104960 Ephb1 Regulation of Positive_regulation of Mapk14 1 0.15 0.42 0.5
155 INT313375 Cnr2 Positive_regulation of Phosphorylation of Mapk14 1 0.18 0.39 0.5
156 INT104961 Mapk14 Regulation of Positive_regulation of Ephb1 1 0.15 0.42 0.5
157 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
158 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
159 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
160 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
161 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
162 INT88889 Binding of HSPG2 and CALCRL 1 0.00 0 0.48
163 INT110031 Positive_regulation of Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
164 INT110030 Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
165 INT110034 Negative_regulation of Adra2c Positive_regulation of Mapk14 1 0.23 0 0.48
166 INT131504 Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.14 0.2 0.47
167 INT131507 Ngf Positive_regulation of Mapk14 1 0.13 0.2 0.47
168 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
169 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
170 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
171 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
172 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
173 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46
174 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
175 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
176 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
177 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45
178 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
179 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
180 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
181 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
182 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44
183 INT343642 Adp Positive_regulation of Localization of Hspg2 1 0.01 0 0.44
184 INT343643 Adp Positive_regulation of Positive_regulation of Hspg2 1 0.01 0 0.43
185 INT264479 Il1a Positive_regulation of Gene_expression of Mapk14 1 0.02 0 0.43
186 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
187 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
188 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
189 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42
190 INT275089 Pde4a Negative_regulation of stm 1 0.02 0.51 0.42
191 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
192 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
193 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41
194 INT319313 Socs4 Positive_regulation of Mapk14 1 0.02 0.68 0.41
195 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
196 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
197 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
198 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
199 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
200 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39

Single Events

The table below shows the top 100 pain related interactions that have been reported for chondrocyte differentiation. They are ordered first by their pain relevance and then by number of times they were reported in chondrocyte differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
2 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
3 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
4 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
5 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
6 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
7 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
8 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
9 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
10 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
11 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
12 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
13 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
14 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
15 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
16 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
17 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
18 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
19 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
20 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
21 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
22 INT117527 Binding of Prkca 25 0.48 6.43 21.05
23 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
24 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
25 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
26 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65
27 INT79458 Localization of Prkca 30 0.81 11.13 15.78
28 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78
29 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
30 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
31 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
32 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
33 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
34 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32
35 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
36 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
37 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
38 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
39 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
40 INT7411 Localization of FGFR3 40 0.78 4.77 10.24
41 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
42 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
43 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
44 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
45 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06
46 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
47 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
48 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03
49 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
50 INT233812 Gene_expression of PTH1R 32 0.77 18.15 6.15
51 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
52 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
53 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
54 INT88784 Negative_regulation of stm 11 0.56 0.51 5.33
55 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
56 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
57 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
58 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
59 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
60 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95
61 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
62 INT17312 Binding of HSPG2 30 0.41 33.01 4.88
63 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
64 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
65 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
66 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
67 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
68 INT115927 Negative_regulation of Hspg2 27 0.57 4.16 4.53
69 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
70 INT107771 Localization of HSPG2 10 0.78 8.47 4.3
71 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
72 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21
73 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
74 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
75 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
76 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
77 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
78 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86
79 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
80 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
81 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
82 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
83 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56
84 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
85 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
86 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
87 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
88 INT236824 Negative_regulation of Gene_expression of PTH1R 10 0.58 9.3 3.42
89 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
90 INT7408 Negative_regulation of FGFR3 12 0.43 2.38 3.33
91 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
92 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
93 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
94 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
95 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
96 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
97 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
98 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
99 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
100 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
101 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
102 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
103 INT7409 Negative_regulation of Localization of FGFR3 12 0.37 2.24 2.92
104 INT126323 Regulation of TGFBI 6 0.59 3.17 2.9
105 INT155453 Protein_catabolism of Mapk14 6 0.36 4.24 2.85
106 INT90094 Gene_expression of Cytl1 14 0.75 12.75 2.81
107 INT96901 Regulation of Negative_regulation of Mapk14 3 0.45 4.07 2.79
108 INT53733 Positive_regulation of FGFR3 6 0.45 1.32 2.76
109 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
110 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
111 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
112 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
113 INT125439 Positive_regulation of NFIB 4 0.67 6.71 2.52
114 INT172592 Positive_regulation of PTH1R 9 0.28 6.25 2.5
115 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
116 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
117 INT7410 Positive_regulation of Localization of FGFR3 9 0.45 1.97 2.36
118 INT36314 Gene_expression of FGFR3 11 0.73 6.21 2.23
119 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
120 INT88783 Positive_regulation of stm 4 0.39 0 1.98
121 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
122 INT120407 Positive_regulation of Localization of HSPG2 2 0.49 2.11 1.92
123 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
124 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
125 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
126 INT118907 Negative_regulation of Negative_regulation of Mapk14 2 0.57 2.09 1.77
127 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74
128 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
129 INT168686 Transcription of Mapk14 6 0.52 2.96 1.67
130 INT248253 Positive_regulation of Gene_expression of HSPG2 3 0.44 4.61 1.65
131 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
132 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
133 INT204277 Positive_regulation of Cytl1 3 0.67 2.56 1.64
134 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
135 INT126322 Negative_regulation of TGFBI 4 0.41 2.12 1.63
136 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
137 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
138 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
139 INT219259 Binding of Nfib 1 0.36 1.46 1.46
140 INT53735 Regulation of FGFR3 4 0.26 0.76 1.45
141 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
142 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
143 INT262545 Positive_regulation of Positive_regulation of Hspg2 4 0.49 1.39 1.41
144 INT145809 Gene_expression of stm 9 0.65 3.66 1.4
145 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
146 INT159378 Localization of Hspg2 6 0.80 0.9 1.35
147 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
148 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
149 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
150 INT202365 Regulation of Gene_expression of Mapk14 6 0.45 4.89 1.26
151 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
152 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
153 INT81235 Regulation of Localization of FGFR3 2 0.26 0 1.12
154 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
155 INT126525 Regulation of Negative_regulation of Mapk14 2 0.41 0.81 1.11
156 INT151261 Negative_regulation of Nfib 2 0.47 2.12 1.11
157 INT90093 Localization of Cytl1 9 0.78 4.85 1.07
158 INT54835 Regulation of Col2a1 5 0.59 2.08 1.07
159 INT233816 Negative_regulation of PTH1R 2 0.58 4.08 1.07
160 INT151260 Gene_expression of Nfib 5 0.75 1.83 1.06
161 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
162 INT120395 Regulation of HSPG2 4 0.26 5.96 1.03
163 INT151262 Binding of Nfib 1 0.36 1.02 1.03
164 INT168233 Positive_regulation of Transcription of Col2a1 2 0.45 1.78 0.99
165 INT178391 Localization of Mapk14 9 0.68 5.27 0.97
166 INT306295 Regulation of NFIB 1 0.13 2.43 0.97
167 INT145028 Positive_regulation of Localization of Mapk14 2 0.20 0.85 0.96
168 INT43484 Binding of Runx2 7 0.37 3.22 0.95
169 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
170 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
171 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
172 INT231494 Regulation of Phosphorylation of Mapk14 2 0.24 2.59 0.93
173 INT235828 Binding of Hspg2 4 0.25 2.24 0.89
174 INT309781 Positive_regulation of Gene_expression of PTH1R 2 0.46 1.88 0.87
175 INT317485 Regulation of Binding of Prkca 1 0.17 0.17 0.87
176 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
177 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
178 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
179 INT275075 Localization of stm 1 0.08 0.06 0.85
180 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
181 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
182 INT168089 Regulation of Localization of HSPG2 2 0.20 0.86 0.81
183 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
184 INT219268 Negative_regulation of Negative_regulation of Mapk14 2 0.38 0.99 0.8
185 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
186 INT148894 Binding of Cytl1 2 0.47 0.99 0.77
187 INT53734 Regulation of Positive_regulation of FGFR3 1 0.26 0 0.77
188 INT306276 Binding of NFIB 1 0.14 1.73 0.77
189 INT180361 Positive_regulation of AMELX 7 0.12 6.03 0.76
190 INT173506 Positive_regulation of Col2a1 4 0.20 3.42 0.76
191 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
192 INT211315 Binding of FGFR3 7 0.35 0.97 0.75
193 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
194 INT120239 Gene_expression of NFIB 3 0.65 1.01 0.72
195 INT37617 Regulation of Gene_expression of Col2a1 3 0.31 1.48 0.7
196 INT166537 Localization of Fgfr1 5 0.40 2.69 0.69
197 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
198 INT314190 Negative_regulation of Localization of Mapk14 1 0.36 0.91 0.69
199 INT272706 Negative_regulation of Localization of Hspg2 2 0.18 0 0.68
200 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
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