GO:0002070

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Name epithelial cell maturation
Categary Process
Go Slim No
Go Link GO:0002070
Unique Molecular Interactions 66
Total Molecular Interactions 87
Total Single Events 1003
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for epithelial cell maturation. They are ordered first by their pain relevance and then by number of times they were reported for epithelial cell maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
2 INT231027 LOC100366054 Negative_regulation of Gene_expression of Pgr 1 0.02 0 0.62
3 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
4 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53
5 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
6 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
7 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
8 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
9 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
10 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
11 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29
12 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
13 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
14 INT103280 PGR Negative_regulation of Positive_regulation of ATF4 1 0.02 0.31 0.26
15 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25
16 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
17 INT318679 Atf4 Positive_regulation of Gene_expression of Xbp1 1 0.53 0.77 0.23
18 INT63193 POMC Positive_regulation of PGR 1 0.17 0.3 0.23
19 INT63199 INS Positive_regulation of PGR 1 0.11 0.3 0.23
20 INT63194 PTH Positive_regulation of PGR 1 0.25 0.29 0.22
21 INT35151 PLOD1 Regulation of PGR 1 0.09 0 0.21
22 INT35152 GH1 Regulation of PGR 1 0.08 0 0.21
23 INT35156 FSHR Regulation of PGR 1 0.18 0 0.21
24 INT318677 Xbp1 Positive_regulation of Ddit3 1 0.73 1.72 0.18
25 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17
26 INT201865 Binding of PGR and NCOA1 1 0.03 0 0.17
27 INT18043 Binding of SIGMAR1 and Pgr 1 0.00 0.06 0.16
28 INT201867 Binding of PGR and PASK 1 0.02 0.23 0.14
29 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09
30 INT341825 Binding of TNC and PGR 1 0.14 0.63 0.09
31 INT287174 Binding of PGR and SHBG 1 0.18 0.11 0.08
32 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07
33 INT201866 Binding of AR and PGR 1 0.07 0.34 0.06
34 INT197586 Esr2 Regulation of Pgr 1 0.09 0 0.06
35 INT215882 Atf4 Regulation of Xbp1 1 0.28 0.43 0.04
36 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03
37 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0
38 INT197615 Esr1 Regulation of Gene_expression of Pgr 1 0.01 0.21 0
39 INT99770 Thbs1 Regulation of PGR 1 0.01 0 0
40 INT208017 Col4a4 Regulation of Gene_expression of Pgr 1 0.04 0.69 0
41 INT218973 Gen1 Regulation of Gene_expression of Pgr 1 0.06 0.09 0
42 INT313596 ESR1 Positive_regulation of Gene_expression of PGR 1 0.05 1 0
43 INT314687 ESR1 Regulation of PGR 1 0.27 0.88 0
44 INT99768 Oxtr Regulation of PGR 1 0.20 0 0
45 INT197614 Esr1 Regulation of Pgr 1 0.01 0.07 0
46 INT191166 Regulation of DBT Positive_regulation of PGR 1 0.01 0 0
47 INT197912 Dlst Positive_regulation of Gene_expression of Pgr 1 0.01 0.34 0
48 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
49 INT191169 DBT Positive_regulation of PGR 1 0.02 0 0
50 INT191170 DBT Positive_regulation of Positive_regulation of PGR 1 0.02 0 0
51 INT256705 Binding of Wfs1 and Xbp1 1 0.19 0.39 0
52 INT197676 ESR1 Regulation of Gene_expression of Pgr 1 0.06 0.1 0
53 INT256704 Xbp1 Positive_regulation of Positive_regulation of Wfs1 1 0.26 0.4 0
54 INT197588 Dlat Regulation of Pgr 1 0.04 0.26 0
55 INT201799 PGR Regulation of HSD17B2 1 0.12 0.08 0
56 INT97181 Tm2d1 Positive_regulation of Transcription of Pgr 1 0.06 0 0
57 INT178628 Igf1 Regulation of Gene_expression of Pgr 1 0.24 0.19 0
58 INT197595 Ppt1 Regulation of Pgr 1 0.08 0.26 0
59 INT186023 Binding of PCA and PGR 1 0.06 0.28 0
60 INT341792 Binding of PLAU and Pgr 1 0.02 0.34 0
61 INT99773 Pgr Regulation of PGR 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for epithelial cell maturation. They are ordered first by their pain relevance and then by number of times they were reported in epithelial cell maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
2 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79
3 INT96218 Positive_regulation of Pgr 17 0.68 5.23 6.57
4 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
5 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67
6 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39
7 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
8 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33
9 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28
10 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85
11 INT136105 Regulation of Pgr 4 0.45 1.93 2.62
12 INT34830 Regulation of PGR 14 0.45 6.99 2.32
13 INT22605 Regulation of Pgr 22 0.62 7.1 2.26
14 INT178632 Regulation of Gene_expression of Pgr 11 0.35 1.56 2.26
15 INT83236 Localization of PGR 14 0.73 8.26 2.23
16 INT13267 Binding of Pgr 15 0.40 3.5 2.22
17 INT87778 Positive_regulation of Gene_expression of Gja1 6 0.69 1.46 2.14
18 INT68496 Binding of PGR 26 0.48 16.36 2.09
19 INT87779 Positive_regulation of Gja1 4 0.53 0.9 1.95
20 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89
21 INT87776 Positive_regulation of Phosphorylation of Gja1 3 0.62 0.71 1.86
22 INT96216 Negative_regulation of Positive_regulation of Pgr 2 0.37 0.74 1.72
23 INT132761 Negative_regulation of Pgr 6 0.50 3.07 1.58
24 INT45711 Localization of Pgr 7 0.61 1.27 1.56
25 INT144671 Gene_expression of Xbp1 4 0.75 8.48 1.4
26 INT184696 Positive_regulation of Xbp1 12 0.60 13.6 1.06
27 INT27938 Negative_regulation of Pgr 12 0.38 1.98 1.05
28 INT172529 Negative_regulation of Gene_expression of PGR 24 0.48 16.69 1.04
29 INT134822 Gene_expression of Gja1 18 0.72 4.2 1
30 INT158737 Localization of Pgr 4 0.10 1.24 0.98
31 INT118558 Gene_expression of Xbp1 13 0.72 7.98 0.91
32 INT178633 Negative_regulation of Gene_expression of Pgr 2 0.21 0.26 0.86
33 INT87777 Regulation of Gja1 1 0.62 0.76 0.81
34 INT143306 Positive_regulation of Gja1 3 0.50 0.42 0.75
35 INT128402 Negative_regulation of Phosphorylation of Gja1 1 0.58 0.73 0.73
36 INT147493 Phosphorylation of Pgr 1 0.69 1.4 0.72
37 INT118567 Regulation of Gene_expression of Xbp1 1 0.23 0.89 0.69
38 INT152909 Regulation of Gene_expression of Gja1 1 0.61 0.46 0.69
39 INT87781 Regulation of Phosphorylation of Gja1 1 0.27 0 0.67
40 INT132759 Positive_regulation of Gene_expression of Pgr 9 0.38 5.12 0.64
41 INT158738 Binding of Pgr 9 0.28 3.49 0.61
42 INT154837 Regulation of Gja1 2 0.45 1.42 0.53
43 INT134820 Positive_regulation of Gene_expression of Gja1 3 0.64 0.84 0.49
44 INT147492 Negative_regulation of Gene_expression of Pgr 2 0.50 0.98 0.49
45 INT87774 Binding of Gja1 2 0.48 0.19 0.48
46 INT140949 Positive_regulation of Positive_regulation of Pgr 4 0.59 1.23 0.42
47 INT202189 Transcription of PGR 5 0.51 0.8 0.4
48 INT157034 Positive_regulation of Xbp1 2 0.45 3.44 0.38
49 INT158739 Positive_regulation of Localization of Pgr 1 0.07 0.36 0.36
50 INT318668 Negative_regulation of Gene_expression of Xbp1 1 0.56 1.53 0.32
51 INT97179 Transcription of Pgr 17 0.67 4.54 0.3
52 INT197602 Negative_regulation of Transcription of Pgr 1 0.25 0.09 0.24
53 INT300941 Regulation of Localization of PGR 1 0.04 1.02 0.24
54 INT306713 Regulation of Positive_regulation of Pgr 1 0.06 0.39 0.24
55 INT92079 Negative_regulation of Binding of Pgr 1 0.34 0 0.22
56 INT126761 Negative_regulation of Gja1 1 0.33 0.08 0.22
57 INT257540 Transcription of Pgr 2 0.04 0.82 0.16
58 INT318673 Negative_regulation of Xbp1 3 0.41 1.51 0.15
59 INT157035 Negative_regulation of Positive_regulation of Xbp1 1 0.15 1.27 0.15
60 INT71905 Regulation of Gene_expression of PGR 6 0.50 1.3 0.14
61 INT184693 Positive_regulation of Gene_expression of Xbp1 3 0.47 4.42 0.13
62 INT208015 Positive_regulation of Positive_regulation of Pgr 2 0.35 0.96 0.13
63 INT257541 Positive_regulation of Transcription of Pgr 1 0.03 0.22 0.13
64 INT344066 Positive_regulation of Binding of PGR 1 0.03 0.63 0.12
65 INT314168 Transcription of Xbp1 4 0.69 1.54 0.1
66 INT155667 Negative_regulation of Gene_expression of Gja1 3 0.42 1.16 0.1
67 INT294171 Regulation of Gene_expression of Pgr 2 0.15 0.93 0.1
68 INT314169 Regulation of Gene_expression of Xbp1 2 0.59 0.69 0.07
69 INT209177 Positive_regulation of Transcription of PGR 1 0.50 0.05 0.07
70 INT263578 Localization of Xbp1 1 0.58 0 0.07
71 INT197611 Regulation of Regulation of Pgr 1 0.16 0 0.06
72 INT318670 Localization of Xbp1 1 0.72 0.58 0.05
73 INT257689 Negative_regulation of Gja1 1 0.37 0.58 0.05
74 INT228786 Regulation of Gene_expression of Gja1 2 0.29 0.49 0.04
75 INT312983 Protein_catabolism of PGR 1 0.11 0.9 0.04
76 INT338876 Binding of Xbp1 1 0.18 0.32 0.04
77 INT228802 Negative_regulation of Gene_expression of Gja1 4 0.37 0.87 0.03
78 INT256691 Binding of Xbp1 4 0.32 1.63 0.03
79 INT216569 Localization of Gja1 2 0.36 0.35 0.03
80 INT291953 Positive_regulation of Binding of Xbp1 1 0.23 0.13 0.03
81 INT27939 Positive_regulation of Negative_regulation of Pgr 6 0.27 1.44 0
82 INT97180 Regulation of Transcription of Pgr 5 0.38 2.2 0
83 INT247813 Localization of Gja1 2 0.45 0.47 0
84 INT247793 Regulation of Localization of Gja1 2 0.17 0.47 0
85 INT218972 Positive_regulation of Binding of Pgr 2 0.28 0.46 0
86 INT197609 Positive_regulation of Transcription of Pgr 1 0.29 0.07 0
87 INT314161 Regulation of Transcription of Xbp1 1 0.24 0.17 0
88 INT296574 Positive_regulation of Positive_regulation of Xbp1 1 0.43 0.85 0
89 INT314160 Regulation of Xbp1 1 0.24 0.1 0
90 INT197610 Negative_regulation of Negative_regulation of Pgr 1 0.25 0.49 0
91 INT197604 Positive_regulation of Regulation of Pgr 1 0.29 0.49 0
92 INT197598 Negative_regulation of Localization of Pgr 1 0.21 0.28 0
93 INT236245 Negative_regulation of Localization of PGR 1 0.02 1.24 0
94 INT197597 Positive_regulation of Localization of Pgr 1 0.25 0.29 0
95 INT68495 Negative_regulation of Binding of PGR 1 0.43 0 0
96 INT314164 Positive_regulation of Transcription of Xbp1 1 0.42 0.19 0
97 INT274710 Positive_regulation of Positive_regulation of PGR 1 0.08 1.21 0
98 INT272385 Negative_regulation of Positive_regulation of Pgr 1 0.04 0.21 0
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