GO:0002080

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Name acrosomal membrane
Categary Component
Go Slim No
Go Link GO:0002080
Unique Molecular Interactions 111
Total Molecular Interactions 157
Total Single Events 1228
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for acrosomal membrane. They are ordered first by their pain relevance and then by number of times they were reported for acrosomal membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
2 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
3 INT190168 BSG Regulation of CDCP1 1 0.00 1.18 0.84
4 INT126598 Binding of BSG and OPRK1 1 0.01 0.05 0.72
5 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66
6 INT96282 Cav2 Regulation of Positive_regulation of Gabrg1 1 0.25 0 0.48
7 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
8 INT145954 Binding of BSG and MME 1 0.00 0.81 0.47
9 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
10 INT297314 Binding of Bsg and Sele 1 0.11 1.37 0.37
11 INT190173 BSG Regulation of MMRN1 1 0.00 0.29 0.35
12 INT177426 Izumo1 Positive_regulation of Positive_regulation of Fig4 1 0.16 0.59 0.34
13 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
14 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
15 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
16 INT177425 Binding of Fig4 and Izumo1 1 0.12 0.59 0.23
17 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
18 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
19 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21
20 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
21 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
22 INT121806 PHF21A Regulation of CAV2 1 0.00 0.24 0.2
23 INT343644 Grm5 Positive_regulation of Cav2 1 0.05 0 0.19
24 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
25 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
26 INT327700 Binding of Comt and 4930579C15Rik 1 0.08 0 0.15
27 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
28 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
29 INT52711 BSG Regulation of ADCY1 1 0.01 0.1 0.12
30 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
31 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
32 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
33 INT327704 Uts2r Positive_regulation of 4930579C15Rik 1 0.03 0.48 0.1
34 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
35 INT116788 Bsg Negative_regulation of Gene_expression of Ptges 1 0.00 0.17 0.09
36 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
37 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
38 INT116792 Bsg Positive_regulation of Protein_catabolism of NOS2 1 0.23 0.18 0.09
39 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
40 INT350909 Binding of Pcsk4 and Twist1 1 0.02 1.91 0.08
41 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
42 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
43 INT232590 Csf2 Positive_regulation of Serpina5 1 0.17 0.65 0.05
44 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
45 INT286187 Serpina5 Positive_regulation of Protein_catabolism of Slco1c1 1 0.01 0.41 0.03
46 INT340741 Binding of ATP5G3 and Gma3 1 0.00 0.96 0.03
47 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
48 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
49 INT258908 Binding of BSG and HLA-DQA1 1 0.00 0.1 0
50 INT279279 Binding of BSG and KLF1 1 0.00 0.65 0
51 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
52 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
53 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
54 INT283715 Lpin1 Regulation of 4930579C15Rik 1 0.35 0.74 0
55 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
56 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
57 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
58 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
59 INT280961 Binding of Cav1 and Cpox 1 0.04 0 0
60 INT305316 Binding of Hgf and Serpina5 1 0.21 1 0
61 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
62 INT250588 Binding of BSG and MCTS1 1 0.11 1.83 0
63 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
64 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
65 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
66 INT288590 Binding of Cav1 and Abhd14a 1 0.00 0 0
67 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
68 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
69 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
70 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
71 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
72 INT305317 Binding of HGF and Serpina5 1 0.04 0.28 0
73 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
74 INT286188 Twist1 Positive_regulation of Serpina5 1 0.02 0 0
75 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
76 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
77 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
78 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
79 INT286185 Slco1c1 Positive_regulation of Serpina5 1 0.01 0.23 0
80 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
81 INT283717 Id2 Regulation of 4930579C15Rik 1 0.15 0.75 0
82 INT214980 Binding of Cav2 and Sigmar1 1 0.02 0.07 0
83 INT298103 Binding of Cav1 and Ca2 1 0.03 0 0
84 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
85 INT220518 Cav1 Negative_regulation of Akt1 1 0.04 1.02 0
86 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
87 INT288592 Binding of Cav1 and Olfr1012 1 0.01 0 0
88 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
89 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
90 INT298104 Ca2 Negative_regulation of Cav1 1 0.04 0.09 0
91 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0
92 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
93 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
94 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
95 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
96 INT220526 Binding of Akt1 and Cav1 1 0.03 1.02 0
97 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0
98 INT351159 CAV1 Positive_regulation of AKT1 1 0.11 0.87 0
99 INT183854 Regulation of CAV1 Positive_regulation of RHOC 1 0.41 0.26 0
100 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for acrosomal membrane. They are ordered first by their pain relevance and then by number of times they were reported in acrosomal membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86
2 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
3 INT37764 Positive_regulation of Izumo1 21 0.61 8.75 5.79
4 INT187189 Positive_regulation of Gene_expression of BSG 1 0.61 6.21 5.02
5 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
6 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
7 INT114472 Regulation of Izumo1 13 0.48 7.95 3.2
8 INT292058 Positive_regulation of Cav2 7 0.67 3.43 2.89
9 INT187187 Regulation of Gene_expression of BSG 3 0.40 3.84 2.8
10 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76
11 INT72812 Positive_regulation of BSG 2 0.49 2.2 2.76
12 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
13 INT282270 Gene_expression of Cav2 11 0.57 3.53 2.72
14 INT37763 Negative_regulation of Izumo1 5 0.51 3.85 2.47
15 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
16 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17
17 INT287525 Localization of CAV2 5 0.47 5.32 2
18 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
19 INT292051 Negative_regulation of Cav2 6 0.41 2.52 1.9
20 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
21 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
22 INT114471 Negative_regulation of Positive_regulation of Izumo1 2 0.45 1.43 1.3
23 INT141862 Binding of Cav1 11 0.36 1.32 1.25
24 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
25 INT305307 Gene_expression of Serpina5 88 0.78 10.09 1
26 INT174839 Localization of BSG 4 0.68 2.91 0.98
27 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
28 INT174029 Protein_catabolism of BSG 5 0.01 2.5 0.95
29 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
30 INT292059 Positive_regulation of Gene_expression of Cav2 3 0.42 0.88 0.92
31 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
32 INT141335 Positive_regulation of Bsg 1 0.02 2.17 0.83
33 INT177422 Gene_expression of Izumo1 1 0.60 1.07 0.79
34 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
35 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
36 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74
37 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
38 INT151877 Positive_regulation of Gene_expression of CAV2 2 0.40 0.39 0.72
39 INT153667 Localization of CAV1 15 0.76 11.92 0.68
40 INT187185 Regulation of BSG 2 0.44 1.61 0.66
41 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
42 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
43 INT141338 Gene_expression of Bsg 1 0.04 1.75 0.59
44 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
45 INT121810 Positive_regulation of CAV2 2 0.28 0.55 0.57
46 INT79839 Positive_regulation of Serpina5 3 0.44 1.2 0.56
47 INT315028 Regulation of Cav2 2 0.43 0.86 0.54
48 INT141334 Positive_regulation of Transcription of Bsg 1 0.02 1.34 0.54
49 INT230676 Gene_expression of 4930579C15Rik 13 0.34 5.61 0.49
50 INT298539 Binding of CAV2 2 0.39 0.95 0.48
51 INT86702 Localization of Cav1 8 0.69 0.76 0.47
52 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
53 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
54 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
55 INT177423 Regulation of Regulation of Izumo1 1 0.21 0.95 0.42
56 INT32100 Negative_regulation of BSG 1 0.03 0 0.4
57 INT343628 Regulation of Positive_regulation of Cav2 1 0.19 0 0.4
58 INT220506 Binding of Cav1 13 0.45 5.46 0.38
59 INT187182 Binding of BSG 7 0.32 2.83 0.37
60 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
61 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
62 INT177420 Positive_regulation of Regulation of Izumo1 1 0.36 0.58 0.34
63 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
64 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
65 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
66 INT292064 Positive_regulation of Positive_regulation of Cav2 1 0.49 0.5 0.28
67 INT141337 Positive_regulation of Positive_regulation of Bsg 1 0.02 0.68 0.27
68 INT141336 Transcription of Bsg 1 0.03 0.65 0.26
69 INT78370 Phosphorylation of BSG 1 0.01 0.05 0.26
70 INT59964 Localization of Pcsk4 3 0.59 2.25 0.23
71 INT174027 Negative_regulation of Protein_catabolism of BSG 1 0.01 0.52 0.23
72 INT214664 Gene_expression of Serpina5 6 0.26 2.91 0.22
73 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
74 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
75 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
76 INT340730 Gene_expression of Gma3 1 0.01 6.67 0.21
77 INT121809 Regulation of Positive_regulation of CAV2 1 0.25 0.26 0.2
78 INT210033 Negative_regulation of Serpina5 4 0.21 3.99 0.19
79 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
80 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
81 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
82 INT177424 Positive_regulation of Gene_expression of Izumo1 1 0.39 0.1 0.16
83 INT329386 Positive_regulation of Localization of CAV2 1 0.17 0.19 0.16
84 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
85 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
86 INT305312 Regulation of Serpina5 3 0.39 1.85 0.14
87 INT214975 Localization of Cav1 7 0.75 2.7 0.13
88 INT50051 Regulation of Pcsk4 2 0.24 1.07 0.13
89 INT264283 Negative_regulation of Regulation of Izumo1 1 0.01 0.73 0.13
90 INT177421 Localization of Izumo1 1 0.58 0.13 0.13
91 INT210032 Binding of Serpina5 4 0.18 1.87 0.12
92 INT246703 Binding of Bsg 1 0.02 2.49 0.1
93 INT232589 Positive_regulation of Serpina5 4 0.19 0.8 0.09
94 INT214973 Binding of Cav2 2 0.03 0.57 0.08
95 INT220491 Transcription of Cav1 2 0.54 1.1 0.07
96 INT220500 Positive_regulation of Transcription of Cav1 1 0.16 0.9 0.07
97 INT305306 Negative_regulation of Gene_expression of Serpina5 1 0.51 0.79 0.06
98 INT220502 Positive_regulation of Positive_regulation of Cav1 1 0.24 0.21 0.05
99 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05
100 INT214968 Localization of Cav2 1 0.05 0.08 0.05
101 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04
102 INT340731 Regulation of Gma3 1 0.00 1.45 0.04
103 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
104 INT230658 Binding of 4930579C15Rik 5 0.17 1.35 0.03
105 INT183878 Negative_regulation of Positive_regulation of CAV1 1 0.41 0.16 0.03
106 INT327684 Positive_regulation of Gene_expression of 4930579C15Rik 1 0.10 0.43 0.03
107 INT286180 Protein_catabolism of Serpina5 1 0.29 0.41 0.03
108 INT283680 Regulation of Gene_expression of 4930579C15Rik 1 0.14 0.91 0.03
109 INT340732 Regulation of Gene_expression of Gma3 1 0.00 1.01 0.03
110 INT305308 Transcription of Serpina5 1 0.60 0.15 0.03
111 INT183883 Binding of CAV1 8 0.46 3.89 0
112 INT193828 Gene_expression of Bsg 3 0.16 0 0
113 INT59962 Gene_expression of Pcsk4 2 0.49 3 0
114 INT283550 Negative_regulation of Binding of Cav1 2 0.33 0.11 0
115 INT298115 Regulation of Binding of Cav1 1 0.12 0 0
116 INT305313 Binding of Serpina5 1 0.37 1.96 0
117 INT305305 Localization of Serpina5 1 0.70 0.31 0
118 INT286179 Regulation of Serpina5 1 0.17 0.13 0
119 INT183890 Regulation of Negative_regulation of CAV1 1 0.43 0.38 0
120 INT305311 Regulation of Gene_expression of Serpina5 1 0.45 0.21 0
121 INT282279 Regulation of Gene_expression of Cav2 1 0.05 0.39 0
122 INT288581 Negative_regulation of Binding of CAV1 1 0.03 0 0
123 INT332316 Negative_regulation of Positive_regulation of Cav2 1 0.22 0 0
124 INT340729 Binding of Gma3 1 0.00 0.47 0
125 INT315010 Negative_regulation of Transcription of Cav1 1 0.34 0.21 0
126 INT332317 Negative_regulation of Gene_expression of Cav2 1 0.25 0 0
127 INT286181 Positive_regulation of Binding of Serpina5 1 0.19 0.18 0
128 INT332315 Positive_regulation of Negative_regulation of Cav2 1 0.26 0 0
129 INT193889 Negative_regulation of Gene_expression of Bsg 1 0.07 0 0
130 INT230680 Regulation of 4930579C15Rik 1 0.16 0 0
131 INT350901 Positive_regulation of Pcsk4 1 0.08 1.59 0
132 INT356068 Positive_regulation of Negative_regulation of Bsg 1 0.12 0 0
133 INT305309 Negative_regulation of Serpina5 1 0.43 0.4 0
134 INT285587 Positive_regulation of Localization of Cav1 1 0.11 0.08 0
135 INT59963 Transcription of Pcsk4 1 0.39 0 0
136 INT356072 Negative_regulation of Bsg 1 0.10 0 0
137 INT288580 Regulation of Binding of CAV1 1 0.03 0 0
138 INT305310 Positive_regulation of Gene_expression of Serpina5 1 0.60 0.39 0
139 INT288574 Negative_regulation of Negative_regulation of Cav1 1 0.33 0.06 0
140 INT250601 Regulation of Binding of BSG 1 0.11 0.5 0
141 INT305304 Negative_regulation of Negative_regulation of Serpina5 1 0.38 0.23 0
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