GO:0002089

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Name lens morphogenesis in camera-type eye
Categary Process
Go Slim No
Go Link GO:0002089
Unique Molecular Interactions 57
Total Molecular Interactions 63
Total Single Events 529
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lens morphogenesis in camera-type eye. They are ordered first by their pain relevance and then by number of times they were reported for lens morphogenesis in camera-type eye. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
2 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
3 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
4 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
5 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
6 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
7 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
8 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
9 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
10 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
11 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
12 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
13 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
14 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
15 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
16 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
17 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
18 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
19 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
20 INT208207 Binding of Cadm1 and Pvrl3 1 0.12 1.06 0.12
21 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
22 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
23 INT133998 Pou2f1 Regulation of Meis1 1 0.02 0 0.04
24 INT134002 Meis1 Regulation of Pou2f1 1 0.02 0 0.04
25 INT133997 Meis1 Regulation of Gene_expression of Npff 1 0.16 0 0.04
26 INT185388 Binding of PVRL1 and TLR2 1 0.15 0.75 0.04
27 INT133988 Kcnip3 Regulation of Meis1 1 0.02 0 0.04
28 INT133990 Meis1 Regulation of Pdx1 1 0.05 0 0.04
29 INT133993 Meis1 Regulation of Pou1f1 1 0.02 0 0.04
30 INT133995 Meis1 Regulation of Kcnip3 1 0.02 0 0.04
31 INT133986 Pou1f1 Regulation of Meis1 1 0.02 0 0.04
32 INT133996 Pdx1 Regulation of Meis1 1 0.05 0 0.04
33 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
34 INT152135 TDRD7 Positive_regulation of Gene_expression of SELP 1 0.26 0 0
35 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
36 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
37 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
38 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
39 INT234985 Binding of Dsg3 and Pitx3 1 0.00 0.3 0
40 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
41 INT233269 Binding of Hoxa10 and Meis1 1 0.38 0.42 0
42 INT233282 Binding of HOXA9 and Meis1 1 0.41 0.21 0
43 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
44 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
45 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
46 INT185268 Binding of Fgf2 and Sox1 1 0.19 0 0
47 INT185272 Binding of Egf and Sox1 1 0.21 0 0
48 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
49 INT233270 Meis1 Regulation of Gene_expression of Itgb3 1 0.47 0 0
50 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
51 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
52 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lens morphogenesis in camera-type eye. They are ordered first by their pain relevance and then by number of times they were reported in lens morphogenesis in camera-type eye. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131308 Gene_expression of Pitx3 11 0.74 3.69 3.5
2 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
3 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
4 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
5 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
6 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
7 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
8 INT185396 Gene_expression of PVRL1 17 0.34 15.18 1.18
9 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
10 INT233237 Gene_expression of Meis1 1 0.77 9.69 1.06
11 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
12 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
13 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
14 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
15 INT118469 Gene_expression of Fgfr3 5 0.72 6.98 0.75
16 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
17 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
18 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
19 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
20 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
21 INT133972 Binding of Meis1 3 0.48 0.53 0.54
22 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
23 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
24 INT185393 Regulation of PVRL1 4 0.24 1.48 0.45
25 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
26 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
27 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
28 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
29 INT131311 Negative_regulation of Pitx3 1 0.56 0.5 0.34
30 INT185401 Regulation of Gene_expression of PVRL1 1 0.27 4.69 0.34
31 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
32 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
33 INT233220 Regulation of Gene_expression of Meis1 1 0.61 1.26 0.3
34 INT328583 Transcription of Pitx3 1 0.21 0.49 0.27
35 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
36 INT328588 Negative_regulation of Gene_expression of Pitx3 1 0.12 0 0.23
37 INT115160 Gene_expression of CITED2 1 0.04 0.45 0.2
38 INT115153 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
39 INT328585 Regulation of Pitx3 1 0.13 0.16 0.18
40 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
41 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
42 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
43 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
44 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
45 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
46 INT233248 Positive_regulation of Gene_expression of Meis1 1 0.69 1.31 0.16
47 INT233233 Positive_regulation of Meis1 1 0.69 0.97 0.15
48 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
49 INT185243 Gene_expression of Sox1 6 0.61 0.91 0.12
50 INT233219 Negative_regulation of Gene_expression of Meis1 1 0.58 1.79 0.1
51 INT185394 Binding of PVRL1 5 0.14 2.94 0.09
52 INT233255 Regulation of Positive_regulation of Meis1 1 0.45 0.35 0.09
53 INT283695 Binding of Sox11 1 0.32 0.18 0.08
54 INT250839 Binding of Fgfr3 1 0.16 0.19 0.08
55 INT185395 Regulation of Regulation of PVRL1 1 0.17 0.53 0.08
56 INT208205 Binding of Pvrl3 1 0.11 0.53 0.06
57 INT185257 Positive_regulation of Sox1 1 0.39 0 0.05
58 INT283696 Localization of Sox11 1 0.65 0.37 0.05
59 INT263800 Positive_regulation of Gene_expression of PVRL1 1 0.22 1.14 0.05
60 INT289614 Positive_regulation of CITED2 1 0.37 0.41 0.03
61 INT233241 Regulation of Meis1 1 0.61 0.48 0.03
62 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
63 INT234879 Binding of Pitx3 2 0.11 1.21 0
64 INT276327 Positive_regulation of Gene_expression of Fgfr3 2 0.43 1.83 0
65 INT243057 Positive_regulation of Fgfr3 1 0.46 0.79 0
66 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
67 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
68 INT303553 Regulation of Gene_expression of Fgfr3 1 0.25 0.3 0
69 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
70 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
71 INT233244 Regulation of Regulation of Meis1 1 0.45 0 0
72 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
73 INT243058 Positive_regulation of Positive_regulation of Fgfr3 1 0.46 0.8 0
74 INT185259 Negative_regulation of Gene_expression of Sox1 1 0.34 0 0
75 INT328584 Positive_regulation of Gene_expression of Pitx3 1 0.13 0.06 0
76 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
77 INT313601 Regulation of CITED2 1 0.00 0.8 0
78 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0
79 INT185402 Negative_regulation of Gene_expression of PVRL1 1 0.17 1.11 0
80 INT233229 Localization of Meis1 1 0.74 0 0
81 INT233214 Transcription of Meis1 1 0.68 0 0
82 INT301359 Positive_regulation of Fgfr3 1 0.19 0.64 0
83 INT233226 Negative_regulation of Localization of Meis1 1 0.42 0 0
84 INT233242 Negative_regulation of Transcription of Meis1 1 0.42 0 0
85 INT301357 Negative_regulation of Positive_regulation of Fgfr3 1 0.16 0.35 0
86 INT311630 Negative_regulation of Tfap2a 1 0.34 0.23 0
87 INT185249 Positive_regulation of Gene_expression of Sox1 1 0.39 0 0
88 INT233230 Regulation of Localization of Meis1 1 0.45 0 0
89 INT319128 Positive_regulation of Binding of Tfap2a 1 0.23 0.5 0
90 INT311626 Negative_regulation of Gene_expression of Tfap2a 1 0.34 0.29 0
91 INT234878 Localization of Pitx3 1 0.01 0.25 0
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