GO:0002118

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Name aggressive behavior
Categary Process
Go Slim No
Go Link GO:0002118
Unique Molecular Interactions 89
Total Molecular Interactions 110
Total Single Events 1644
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aggressive behavior. They are ordered first by their pain relevance and then by number of times they were reported for aggressive behavior. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
2 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
3 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
4 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
5 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
6 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
7 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
8 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
9 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
10 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
11 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
12 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
13 INT339331 Binding of TACR1 and SFTPA1 1 0.04 0.12 1.14
14 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
15 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
16 INT94205 TACR1 Regulation of Gene_expression of SP5 1 0.04 0.72 1.06
17 INT339333 Binding of TACR1 and TAC4 1 0.48 0.32 1.05
18 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
19 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
20 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
21 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
22 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
23 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
24 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
25 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
26 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
27 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
28 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
29 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
30 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82
31 INT84103 TACR1 Regulation of Nka1 1 0.00 0 0.81
32 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
33 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
34 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
35 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79
36 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
37 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77
38 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
39 INT95458 Nka1 Positive_regulation of Positive_regulation of Tacr1 1 0.52 0.16 0.77
40 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77
41 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
42 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
43 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
44 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
45 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
46 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65
47 INT189020 Tacr1 Positive_regulation of Pla2g1b 1 0.14 0.13 0.65
48 INT124904 Binding of Tacr1 and Adarb1 2 0.01 0.5 0.63
49 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
50 INT167859 Tac1 Regulation of Gene_expression of Tacr1 1 0.09 0 0.6
51 INT81606 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.29 0 0.6
52 INT81605 PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.43 0 0.57
53 INT339337 Binding of SARDH and TACR1 1 0.01 0.06 0.57
54 INT339335 Binding of MET and TACR1 1 0.06 0.06 0.57
55 INT69898 Binding of Olfr19 and Tacr1 1 0.00 0.1 0.55
56 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
57 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52
58 INT15273 Calca Regulation of Tacr1 1 0.22 0 0.5
59 INT157003 Gal Regulation of Localization of Tacr1 1 0.01 0.1 0.49
60 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
61 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
62 INT127395 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Tacr1 1 0.07 0.71 0.45
63 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42
64 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42
65 INT151633 Binding of Npy and Tacr1 1 0.16 0.39 0.4
66 INT282820 Binding of TACR1 and NCOR2 1 0.00 0.88 0.39
67 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38
68 INT63706 TACR1 Negative_regulation of B3GAT1 1 0.02 0.12 0.37
69 INT63707 TACR1 Negative_regulation of TAC1 1 0.03 0.12 0.37
70 INT207408 Il6 Positive_regulation of Gene_expression of Tacr1 1 0.08 0.56 0.33
71 INT207409 Ptger2 Positive_regulation of Gene_expression of Tacr1 1 0.04 0.56 0.32
72 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
73 INT75108 Binding of Tac2 and Tacr1 1 0.18 0.1 0.29
74 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
75 INT124340 Tacr1 Positive_regulation of Tac2 1 0.48 0 0.27
76 INT208936 Tac1 Positive_regulation of Tacr1 1 0.13 0.39 0.25
77 INT278581 Tacr2 Positive_regulation of Tacr1 1 0.55 0 0.24
78 INT278578 Tacr3 Positive_regulation of Tacr1 1 0.55 0 0.24
79 INT278570 Nka1 Positive_regulation of Tacr1 1 0.06 0 0.24
80 INT65525 Tacr1 Regulation of Regulation of Spn 1 0.15 0.36 0.22
81 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21
82 INT107032 Binding of Tacr1 and Oprm1 1 0.31 0.5 0.21
83 INT330485 MSR1 Negative_regulation of TACR1 1 0.01 0.23 0.13
84 INT271478 Tacr1 Regulation of Binding of Mthfd1 1 0.09 0.48 0.13
85 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
86 INT208939 Positive_regulation of Tacr1 Positive_regulation of Nfkb1 1 0.19 0 0.1
87 INT275800 Binding of Sh2d1a and Tacr1 1 0.01 0.29 0.07
88 INT346529 Binding of PTH1R and TACR1 1 0.00 0 0.05
89 INT78911 TACR1 Positive_regulation of Localization of Nka1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for aggressive behavior. They are ordered first by their pain relevance and then by number of times they were reported in aggressive behavior. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
2 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
3 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
4 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
5 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
6 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
7 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
8 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
9 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
10 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
11 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
12 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
13 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
14 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
15 INT57580 Positive_regulation of TACR1 18 0.69 9.35 12.47
16 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
17 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
18 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
19 INT51168 Localization of TACR1 10 0.80 7.66 9.83
20 INT53547 Binding of TACR1 22 0.48 5.03 9.48
21 INT51837 Negative_regulation of TACR1 17 0.43 6.5 9.12
22 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
23 INT81610 Phosphorylation of TACR1 1 0.81 0.76 8.38
24 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
25 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
26 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
27 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
28 INT14388 Regulation of TACR1 12 0.45 3.1 5.58
29 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
30 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
31 INT81609 Positive_regulation of Phosphorylation of TACR1 1 0.60 0.33 4.91
32 INT92446 Positive_regulation of Gene_expression of TACR1 4 0.35 2.68 4.5
33 INT14936 Negative_regulation of Binding of Tacr1 4 0.58 0.75 3.67
34 INT107950 Regulation of Gene_expression of Tacr1 6 0.61 1.13 2.84
35 INT65126 Transcription of Tacr1 5 0.63 3.44 2.77
36 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73
37 INT122367 Positive_regulation of Positive_regulation of Tacr1 5 0.46 1.47 2.4
38 INT94814 Negative_regulation of Positive_regulation of TACR1 2 0.26 1.98 2.35
39 INT91046 Negative_regulation of Regulation of Tacr1 3 0.40 1.33 2.31
40 INT98898 Localization of Tacr1 6 0.72 2.47 2.25
41 INT136471 Phosphorylation of Tacr1 4 0.46 1.03 1.99
42 INT37220 Regulation of Gene_expression of TACR1 2 0.43 0.46 1.73
43 INT14856 Regulation of Negative_regulation of Tacr1 1 0.20 0.21 1.46
44 INT100569 Positive_regulation of Binding of Tacr1 1 0.50 0.66 1.37
45 INT49204 Protein_catabolism of Tacr1 3 0.50 0.84 1.24
46 INT65124 Negative_regulation of Positive_regulation of Tacr1 3 0.53 0.9 1.18
47 INT105916 Negative_regulation of Gene_expression of TACR1 1 0.03 0.53 1.13
48 INT78812 Transcription of TACR1 4 0.68 0.93 1.05
49 INT219031 Positive_regulation of Regulation of Tacr1 1 0.26 0.65 0.95
50 INT14935 Regulation of Binding of Tacr1 1 0.24 0 0.88
51 INT132587 Negative_regulation of Gene_expression of Tacr1 3 0.57 1.22 0.85
52 INT165240 Negative_regulation of Transcription of Tacr1 3 0.42 0.81 0.74
53 INT81611 Regulation of Phosphorylation of TACR1 1 0.45 0.08 0.59
54 INT167854 Positive_regulation of Regulation of Tacr1 1 0.41 0 0.59
55 INT51159 Positive_regulation of Binding of Tacr1 1 0.34 0.17 0.59
56 INT167857 Positive_regulation of Localization of Tacr1 1 0.44 0 0.59
57 INT99832 Regulation of Negative_regulation of Tacr1 2 0.27 1.28 0.56
58 INT51157 Regulation of Binding of Tacr1 1 0.31 0.2 0.56
59 INT219033 Regulation of Transcription of Tacr1 1 0.15 0.62 0.46
60 INT131108 Positive_regulation of Positive_regulation of TACR1 1 0.12 0.84 0.35
61 INT84195 Negative_regulation of Binding of Tacr1 1 0.02 0 0.32
62 INT67725 Positive_regulation of Binding of TACR1 1 0.04 0.09 0.28
63 INT113391 Regulation of Positive_regulation of Tacr1 2 0.35 0.5 0.27
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