GO:0002133

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Name polycystin complex
Categary Component
Go Slim No
Go Link GO:0002133
Unique Molecular Interactions 43
Total Molecular Interactions 65
Total Single Events 221
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for polycystin complex. They are ordered first by their pain relevance and then by number of times they were reported for polycystin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
2 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
3 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
4 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
5 INT241250 Binding of Pkd2 and Trpc1 1 0.23 0.3 0.17
6 INT126943 Binding of Pkd1 and ZACN 1 0.00 0.69 0.14
7 INT148329 Pkd1 Positive_regulation of Trpv1 1 0.55 0.39 0.13
8 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1
9 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1
10 INT241252 Binding of Pkd1 and Tbpl1 1 0.02 0.79 0.1
11 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1
12 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09
13 INT241249 Pkd2 Regulation of Trpc1 1 0.21 0.14 0.09
14 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09
15 INT131130 Binding of PKD1 and Krt16 1 0.01 1 0.08
16 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
17 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06
18 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
19 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
20 INT241251 Pkd2 Negative_regulation of Gene_expression of Gopc 1 0.12 0.24 0.03
21 INT245158 AD5 Regulation of PKD1 1 0.00 0.44 0
22 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
23 INT286571 Binding of Prkd1 and Pkd1 1 0.05 0.76 0
24 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
25 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
26 INT286574 Gene_expression of Pkd1 Negative_regulation of Cdk2 1 0.10 0.09 0
27 INT286570 Pkd2 Positive_regulation of Binding of Pkd1 1 0.21 0.73 0
28 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0
29 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
30 INT286593 Binding of Pkd1 and GOPC 1 0.02 1.13 0
31 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
32 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0
33 INT286573 Pkd2 Regulation of Pkd1 1 0.12 0.25 0
34 INT286564 Pkd1 Regulation of Mtor 1 0.00 0.51 0
35 INT286569 Binding of Pkd1 and Tsc2 1 0.06 1.01 0
36 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
37 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
38 INT286594 Binding of LILRB1 and Pkd1 1 0.01 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for polycystin complex. They are ordered first by their pain relevance and then by number of times they were reported in polycystin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148326 Gene_expression of Pkd1 7 0.76 5.38 1.85
2 INT148321 Positive_regulation of Gene_expression of Pkd1 5 0.68 2.93 1.21
3 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
4 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
5 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
6 INT241235 Binding of Pkd2 11 0.48 2.43 0.55
7 INT241243 Gene_expression of Pkd2 30 0.77 9.05 0.53
8 INT148322 Localization of Pkd1 1 0.79 1.07 0.41
9 INT241236 Negative_regulation of Pkd2 11 0.43 1.82 0.39
10 INT150826 Positive_regulation of Pkd1 9 0.37 3.65 0.35
11 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27
12 INT241238 Positive_regulation of Pkd2 5 0.46 1.44 0.24
13 INT241244 Localization of Pkd2 1 0.74 0.35 0.24
14 INT208476 Binding of Pkd1 13 0.39 7.23 0.17
15 INT199521 Protein_catabolism of PKD1 2 0.96 0.39 0.15
16 INT148323 Binding of Pkd1 1 0.37 0.5 0.15
17 INT354535 Regulation of Negative_regulation of Pkd2 1 0.15 1.03 0.14
18 INT148324 Phosphorylation of Pkd1 1 0.81 0.52 0.14
19 INT307335 Positive_regulation of Binding of Pkd1 1 0.35 0.23 0.12
20 INT286583 Localization of PKD2 1 0.35 0.17 0.06
21 INT354537 Positive_regulation of Positive_regulation of Pkd1 1 0.29 1.7 0.06
22 INT211006 Binding of PKD1 6 0.22 2.69 0.05
23 INT261879 Binding of PKD2 3 0.13 2.59 0.05
24 INT286543 Localization of Pkd1 5 0.52 3.74 0.04
25 INT241241 Positive_regulation of Gene_expression of Pkd2 3 0.50 1.3 0.03
26 INT271915 Negative_regulation of Pkd1 8 0.36 6.44 0
27 INT150827 Regulation of Pkd1 4 0.32 2.18 0
28 INT241239 Regulation of Pkd2 2 0.27 0.55 0
29 INT175892 Negative_regulation of PKD1 2 0.42 1.03 0
30 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
31 INT286546 Negative_regulation of Gene_expression of Pkd2 2 0.27 0.57 0
32 INT352724 Regulation of Gene_expression of Pkd2 1 0.10 0 0
33 INT352716 Negative_regulation of Regulation of Pkd2 1 0.15 0.08 0
34 INT286545 Positive_regulation of Gene_expression of Pkd1 1 0.42 1.55 0
35 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
36 INT175898 Positive_regulation of PKD1 1 0.50 1.24 0
37 INT261880 Negative_regulation of Binding of PKD1 1 0.16 0.6 0
38 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
39 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
40 INT286554 Negative_regulation of Gene_expression of Pkd1 1 0.35 1.77 0
41 INT175896 Transcription of PKD1 1 0.53 1.22 0
42 INT175890 Negative_regulation of Gene_expression of PKD1 1 0.42 0.11 0
43 INT214908 Positive_regulation of Gene_expression of PKD1 1 0.35 0.86 0
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