GO:0002149

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Name hypochlorous acid biosynthetic process
Categary Process
Go Slim No
Go Link GO:0002149
Unique Molecular Interactions 83
Total Molecular Interactions 101
Total Single Events 2243
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hypochlorous acid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for hypochlorous acid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9
2 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
3 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
4 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79
5 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
6 INT123556 Shfm1 Regulation of Mpo 1 0.09 0.88 0.76
7 INT158607 Ns5atp9 Positive_regulation of Mpo 1 0.35 1.85 0.75
8 INT109718 Tac1 Negative_regulation of Mpo 1 0.25 0.81 0.67
9 INT109717 Calca Negative_regulation of Mpo 1 0.16 0.8 0.67
10 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
11 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51
12 INT157709 CRX Positive_regulation of Mpo 1 0.08 1.11 0.5
13 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49
14 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
15 INT58633 Negative_regulation of Il1f5 Negative_regulation of Mpo 1 0.15 0.98 0.48
16 INT58634 Negative_regulation of Il1 Negative_regulation of Mpo 1 0.20 0.98 0.47
17 INT222923 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of Mpo 1 0.04 0.59 0.45
18 INT99160 Binding of Mpo and Nrm 1 0.38 0.92 0.45
19 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38
20 INT158606 Negative_regulation of Ns5atp9 Positive_regulation of Mpo 1 0.30 0.93 0.38
21 INT158608 Positive_regulation of Ns5atp9 Positive_regulation of Mpo 1 0.25 0.93 0.37
22 INT161517 Mpo Positive_regulation of Gene_expression of Il17a 1 0.22 1.42 0.36
23 INT99159 Nrm Positive_regulation of Mpo 1 0.44 0.85 0.36
24 INT138015 Binding of Paf and Positive_regulation of Mpo 1 0.23 0.53 0.33
25 INT138014 Gm2170 Negative_regulation of Positive_regulation of Mpo 1 0.01 0.53 0.32
26 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29
27 INT319753 Mpo Positive_regulation of Timp1 1 0.14 2.13 0.29
28 INT70096 Csrp3 Positive_regulation of Mpo 1 0.10 0.19 0.28
29 INT85531 Rian Negative_regulation of Mpo 1 0.03 1.36 0.27
30 INT156589 Hst1 Negative_regulation of Mpo 1 0.41 0.95 0.26
31 INT228703 MPO Regulation of Positive_regulation of CRP 1 0.40 1.63 0.2
32 INT273658 Dss1 Positive_regulation of Mpo 1 0.16 0.98 0.19
33 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19
34 INT2433 Mrf Positive_regulation of Mpo 1 0.33 0.65 0.18
35 INT229421 Atp6v0a2 Negative_regulation of Positive_regulation of Mpo 1 0.03 2.8 0.16
36 INT229422 Atp6v0a2 Regulation of Mpo 1 0.03 3.39 0.15
37 INT2927 Positive_regulation of Mpo Positive_regulation of Localization of LH 1 0.26 0.28 0.14
38 INT96801 Nxnl1 Negative_regulation of Mpo 1 0.01 0.62 0.13
39 INT5651 Ptger1 Negative_regulation of Positive_regulation of Mpo 1 0.00 0.34 0.13
40 INT46469 Mpo Positive_regulation of Localization of LH 1 0.45 0.95 0.1
41 INT303123 Gpt Positive_regulation of Gene_expression of Mpo 1 0.22 0.99 0.08
42 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08
43 INT303125 Nos2 Positive_regulation of Gene_expression of Mpo 1 0.34 0.99 0.08
44 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08
45 INT355641 Positive_regulation of MPO Positive_regulation of Gene_expression of ROS1 1 0.24 0.84 0.07
46 INT21446 Ambp Negative_regulation of Positive_regulation of Mpo 1 0.01 0 0.07
47 INT76965 Mpo Negative_regulation of DLD 1 0.26 0.91 0.07
48 INT227353 Binding of Cat and Mpo 1 0.18 0.56 0.07
49 INT255166 Binding of MOCS1 and MPO 1 0.00 0.7 0.05
50 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
51 INT191760 NFASC Positive_regulation of Localization of MPO 1 0.00 0.55 0.04
52 INT191761 FPR1 Regulation of Localization of MPO 1 0.02 0.52 0.03
53 INT120548 Binding of Crp and Mpo 1 0.13 0.05 0
54 INT120549 Binding of ESR1 and Mpo 1 0.26 0.05 0
55 INT285403 Binding of CAT and MPO 1 0.30 0.9 0
56 INT96046 Rasgrp1 Negative_regulation of Mpo 1 0.23 0.06 0
57 INT229418 Mpo Positive_regulation of Sod1 1 0.20 0.71 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hypochlorous acid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in hypochlorous acid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
2 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
3 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42
4 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99
5 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51
6 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22
7 INT5904 Localization of MPO 62 0.81 36.37 14.64
8 INT4460 Regulation of Mpo 44 0.62 31.16 12.11
9 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92
10 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
11 INT12563 Localization of Mpo 33 0.81 20.99 9.58
12 INT127378 Localization of Mpo 21 0.78 26.36 8.28
13 INT56223 Positive_regulation of MPO 35 0.70 43 8.2
14 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99
15 INT2925 Positive_regulation of Positive_regulation of Mpo 21 0.70 16.76 6.36
16 INT5903 Negative_regulation of Localization of MPO 10 0.59 5.71 5.45
17 INT25634 Binding of Mpo 21 0.48 14.78 4.39
18 INT111514 Positive_regulation of Gene_expression of Mpo 20 0.49 15.13 3.88
19 INT14994 Positive_regulation of Localization of MPO 12 0.70 6.85 3.37
20 INT117476 Negative_regulation of Gene_expression of Mpo 10 0.43 8.25 3.33
21 INT24983 Binding of MPO 18 0.42 17.56 3.29
22 INT124606 Positive_regulation of Gene_expression of Mpo 14 0.49 12.66 3.24
23 INT84320 Negative_regulation of Positive_regulation of Mpo 11 0.46 8 3.09
24 INT58302 Regulation of Mpo 13 0.62 11.14 3.04
25 INT111516 Transcription of Mpo 7 0.68 7.97 2.82
26 INT108263 Negative_regulation of Gene_expression of Mpo 12 0.52 12.89 2.22
27 INT228707 Positive_regulation of Gene_expression of MPO 10 0.57 17.85 2.1
28 INT56221 Regulation of MPO 8 0.61 8.44 1.84
29 INT57207 Protein_catabolism of Mpo 9 1.00 3.89 1.7
30 INT127381 Regulation of Localization of Mpo 3 0.54 1.81 1.63
31 INT204563 Binding of Mpo 16 0.37 12.1 1.56
32 INT124604 Positive_regulation of Negative_regulation of Mpo 3 0.47 1.67 1.24
33 INT162970 Regulation of Gene_expression of Mpo 8 0.41 9.1 1.21
34 INT111517 Positive_regulation of Transcription of Mpo 4 0.50 4.5 1.05
35 INT228706 Negative_regulation of Gene_expression of MPO 4 0.43 5.95 0.98
36 INT121823 Negative_regulation of Negative_regulation of Mpo 4 0.39 2.37 0.97
37 INT228705 Regulation of Gene_expression of MPO 2 0.45 5.59 0.94
38 INT127380 Protein_catabolism of Mpo 5 0.86 2.82 0.88
39 INT70696 Positive_regulation of Localization of Mpo 2 0.44 2.17 0.82
40 INT127382 Negative_regulation of Protein_catabolism of Mpo 1 0.41 0.69 0.8
41 INT14000 Positive_regulation of Negative_regulation of Mpo 3 0.40 2.07 0.69
42 INT354978 Negative_regulation of Localization of Mpo 1 0.52 1.32 0.66
43 INT138011 Positive_regulation of Positive_regulation of Mpo 3 0.42 3.84 0.65
44 INT50512 Negative_regulation of Binding of Mpo 2 0.43 2.11 0.61
45 INT283301 Positive_regulation of Localization of Mpo 2 0.44 2.38 0.54
46 INT2430 Negative_regulation of Negative_regulation of Mpo 2 0.37 2.44 0.5
47 INT129857 Regulation of Gene_expression of Mpo 4 0.42 4.36 0.47
48 INT177469 Transcription of MPO 3 0.69 3.08 0.44
49 INT178806 Transcription of Mpo 6 0.64 4.73 0.42
50 INT165630 Positive_regulation of Regulation of Mpo 2 0.39 1.49 0.42
51 INT229392 Negative_regulation of Positive_regulation of MPO 2 0.20 2.18 0.32
52 INT57206 Negative_regulation of Protein_catabolism of Mpo 1 0.43 0.37 0.27
53 INT347412 Negative_regulation of Localization of Mpo 1 0.05 0.59 0.24
54 INT281349 Positive_regulation of Binding of Mpo 1 0.50 1.62 0.22
55 INT204567 Negative_regulation of Binding of Mpo 1 0.42 0.93 0.15
56 INT155372 Negative_regulation of Transcription of Mpo 1 0.35 0.75 0.12
57 INT228704 Negative_regulation of Transcription of MPO 1 0.43 1.47 0.09
58 INT21445 Regulation of Regulation of Mpo 1 0.09 0 0.09
59 INT153827 Phosphorylation of Mpo 2 0.71 0.84 0.08
60 INT222920 Negative_regulation of Transcription of Mpo 1 0.33 0.24 0.08
61 INT169412 Regulation of Binding of Mpo 1 0.62 0.84 0.06
62 INT204565 Regulation of Transcription of Mpo 1 0.26 0.46 0.03
63 INT178794 Positive_regulation of Transcription of Mpo 1 0.40 0.76 0
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