GO:0002193

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Name MAML1-RBP-Jkappa- ICN1 complex
Categary Component
Go Slim No
Go Link GO:0002193
Unique Molecular Interactions 64
Total Molecular Interactions 85
Total Single Events 455
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for MAML1-RBP-Jkappa- ICN1 complex. They are ordered first by their pain relevance and then by number of times they were reported for MAML1-RBP-Jkappa- ICN1 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
3 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
4 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
5 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
6 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
7 INT316064 Binding of RBPJ and Csl 1 0.16 0.33 0.2
8 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
9 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
10 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
11 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
12 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
13 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
14 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
15 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
16 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
17 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
18 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
19 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
20 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
21 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
22 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
23 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
24 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
25 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
26 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
27 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
28 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
29 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
30 INT327873 Postn Regulation of Notch1 1 0.41 0 0
31 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
32 INT356083 Binding of App and Notch1 1 0.02 0.2 0
33 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
34 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
35 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
36 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
37 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
38 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
39 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
40 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
41 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
42 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
43 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
44 INT299456 Binding of Gabpa and Notch1 1 0.21 0.09 0
45 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
46 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for MAML1-RBP-Jkappa- ICN1 complex. They are ordered first by their pain relevance and then by number of times they were reported in MAML1-RBP-Jkappa- ICN1 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
2 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
3 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
4 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
5 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
6 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
7 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
8 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
9 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
10 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
11 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
12 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
13 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
14 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
15 INT110780 Localization of Notch1 2 0.06 0.47 1.19
16 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
17 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
18 INT6833 Binding of Notch1 4 0.36 0.05 0.94
19 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
20 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
21 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
22 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
23 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
24 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
25 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
26 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
27 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
28 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
29 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
30 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
31 INT193945 Binding of Notch1 7 0.15 1.28 0.19
32 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
33 INT297239 Positive_regulation of Gene_expression of Notch1 2 0.40 1.31 0.13
34 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
35 INT316042 Negative_regulation of Gene_expression of Notch1 1 0.27 1.7 0.12
36 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
37 INT327728 Regulation of Gene_expression of Notch1 2 0.27 0.73 0.07
38 INT193845 Localization of Notch1 2 0.78 0.32 0.05
39 INT193850 Regulation of Localization of Notch1 1 0.14 0.33 0.05
40 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
41 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
42 INT232397 Protein_catabolism of Notch1 3 0.64 1.56 0
43 INT297242 Transcription of Notch1 1 0.19 0.25 0
44 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
45 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
46 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
47 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
48 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0
49 INT327858 Positive_regulation of Protein_catabolism of Notch1 1 0.45 0.13 0
50 INT258553 Binding of RBPJ 1 0.11 1.06 0
51 INT327861 Positive_regulation of Localization of Notch1 1 0.67 0 0
52 INT273836 Positive_regulation of Regulation of Notch1 1 0.15 0.05 0
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