GO:0002230

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Name positive regulation of defense response to virus by host
Categary Process
Go Slim No
Go Link GO:0002230
Unique Molecular Interactions 154
Total Molecular Interactions 217
Total Single Events 1783
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of defense response to virus by host. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of defense response to virus by host. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
4 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
5 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
6 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
7 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
8 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93
9 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
10 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89
11 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
12 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
13 INT163946 Binding of ERAP1 and Il23r 1 0.23 0.56 0.72
14 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
15 INT160716 Binding of KIR3DL1 and Il23r 1 0.20 0.72 0.72
16 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
17 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
18 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
19 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
20 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
21 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
22 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
23 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
24 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6
25 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57
26 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
27 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
28 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
29 INT341593 Binding of HLA-E and IL23R 1 0.15 1.15 0.5
30 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
31 INT348173 Binding of HLA-B and IL23R 1 0.15 0.92 0.49
32 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45
33 INT339648 Binding of IL23A and Il23a 1 0.04 0.13 0.44
34 INT246024 IL23A Positive_regulation of SOCS2 1 0.01 0.99 0.43
35 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39
36 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39
37 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39
38 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39
39 INT217028 Adp Negative_regulation of Il12b 1 0.00 0 0.37
40 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36
41 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34
42 INT167596 Il23a Positive_regulation of Gene_expression of Ifng 1 0.13 0.94 0.32
43 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31
44 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29
45 INT300548 Napa Positive_regulation of Gene_expression of Il23a 1 0.05 0.86 0.28
46 INT237088 Binding of Cxcl9 and Ccl5 1 0.29 1.51 0.26
47 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
48 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 0.13 0.83 0.26
49 INT300546 Binding of Il23a and Il1 1 0.01 0.5 0.25
50 INT325313 IL23A Positive_regulation of Gene_expression of IL22 1 0.20 0.48 0.23
51 INT318994 Il17a Regulation of Il23a 1 0.00 1.38 0.22
52 INT306714 IL23A Positive_regulation of TNF 1 0.29 0.5 0.21
53 INT263007 Binding of HLA-DRB6 and IL23R 1 0.01 1.09 0.21
54 INT219153 IL6 Positive_regulation of IL23A 1 0.02 0.45 0.21
55 INT306744 IL23A Positive_regulation of Il12a 1 0.13 0.59 0.2
56 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19
57 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18
58 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17
59 INT306747 IL23A Positive_regulation of Il17a 1 0.05 0.51 0.16
60 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 0.27 1.28 0.16
61 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15
62 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
63 INT346450 Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
64 INT316535 Il23a Regulation of Il12a 1 0.07 1.15 0.15
65 INT290314 MAVS Positive_regulation of DDX58 1 0.06 0.63 0.13
66 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13
67 INT313913 Binding of Il23a and Il23r 1 0.24 0.43 0.13
68 INT313914 Binding of Il12a and Il23r 1 0.14 0.44 0.13
69 INT289253 Il23a Positive_regulation of Stat3 1 0.04 0.37 0.12
70 INT217027 Adp Positive_regulation of Gene_expression of Il23a 1 0.00 0 0.12
71 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
72 INT296032 IL6 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
73 INT265211 Il4 Negative_regulation of Il23a 1 0.01 0.07 0.1
74 INT286964 IL23A Positive_regulation of STAT3 1 0.05 0.57 0.09
75 INT338432 Il23a Positive_regulation of Gene_expression of IL8 1 0.01 1.63 0.09
76 INT296035 IL21 Positive_regulation of Gene_expression of IL23R 1 0.01 0.05 0.08
77 INT186767 Ccl11 Regulation of Ccl5 1 0.01 0 0.07
78 INT186766 Il5 Regulation of Ccl5 1 0.01 0 0.07
79 INT246441 Ccl5 Positive_regulation of Gene_expression of Aif1 1 0.03 0.71 0.06
80 INT246436 Ccl5 Regulation of Aif1 1 0.01 0.67 0.06
81 INT317426 Binding of CSF2 and PML 1 0.08 1.25 0.06
82 INT186375 TNF Negative_regulation of Gene_expression of Il12b 1 0.03 0.78 0.06
83 INT243633 Il23a Positive_regulation of Gene_expression of Twist1 1 0.14 0.11 0.05
84 INT247774 Binding of Ccl5 and Ccrl2 1 0.14 0.29 0.04
85 INT247766 Binding of Ccl2 and Ccl5 1 0.14 0.28 0.04
86 INT346453 Binding of DDX58 and IFIH1 1 0.00 1.04 0.03
87 INT233387 Binding of SPINK1 and Il12b 1 0.04 0.33 0
88 INT204997 Ppp1r15b Regulation of Mavs 1 0.00 0.87 0
89 INT283979 TLR2 Positive_regulation of Gene_expression of IL23A 1 0.09 0.96 0
90 INT316537 Binding of Tlr1 and Il23a 1 0.12 0.78 0
91 INT152401 Binding of Il1a and Il23r 1 0.00 0.06 0
92 INT331685 IRF6 Positive_regulation of IL23A 1 0.03 0.14 0
93 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
94 INT229176 LILRB1 Negative_regulation of KIR3DL1 1 0.02 0.29 0
95 INT217314 IFNA1 Positive_regulation of MAVS 1 0.01 1.47 0
96 INT316536 Binding of Tlr2 and Il23a 1 0.11 0.78 0
97 INT286594 Binding of LILRB1 and Pkd1 1 0.01 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of defense response to virus by host. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of defense response to virus by host. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15
2 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
3 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67
4 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
5 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
6 INT226463 Positive_regulation of IL23A 23 0.45 21.58 9.18
7 INT213886 Binding of IL23R 7 0.46 16.79 6.94
8 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
9 INT150023 Positive_regulation of Il23a 25 0.38 18.33 6.32
10 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
11 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05
12 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
13 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
14 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
15 INT160565 Gene_expression of Il23r 6 0.56 10.01 4.51
16 INT204783 Positive_regulation of Gene_expression of Il23a 17 0.36 15.53 4.42
17 INT139533 Binding of Il23r 17 0.47 7.67 4.14
18 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
19 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
20 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
21 INT181378 Negative_regulation of Gene_expression of Ccl5 12 0.46 9.64 3.59
22 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37
23 INT250884 Binding of IL23A 5 0.19 7.17 3.17
24 INT163269 Binding of Il23a 11 0.44 7.2 3.14
25 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
26 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19
27 INT250888 Negative_regulation of IL23A 4 0.30 6.13 2.15
28 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04
29 INT258780 Regulation of Il23a 6 0.13 4.77 1.96
30 INT92056 Transcription of Il12b 8 0.69 4.75 1.95
31 INT133170 Negative_regulation of Il12b 12 0.05 5.32 1.86
32 INT151039 Binding of Il23r 8 0.42 3.01 1.86
33 INT97062 Binding of PML 10 0.41 11.63 1.65
34 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56
35 INT250890 Gene_expression of IL23R 2 0.12 3.11 1.53
36 INT8707 Localization of LILRB1 2 0.60 1.5 1.5
37 INT97142 Localization of IL12B 5 0.73 1.73 1.46
38 INT202035 Gene_expression of LILRB1 5 0.75 4.78 1.41
39 INT237772 Localization of Il23a 5 0.42 4.16 1.34
40 INT157817 Negative_regulation of Il23a 6 0.39 3.34 1.33
41 INT135406 Transcription of Il23a 3 0.32 3.15 1.31
42 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
43 INT236329 Regulation of IL12B 3 0.02 0.78 1.2
44 INT92055 Positive_regulation of Transcription of Il12b 4 0.49 2.77 1.16
45 INT246028 Positive_regulation of IL23R 3 0.46 2.74 1.15
46 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
47 INT233357 Localization of Il12b 7 0.16 3.4 1.12
48 INT162384 Gene_expression of Il23r 4 0.77 1.03 1.12
49 INT250886 Positive_regulation of Gene_expression of IL23R 2 0.08 1.91 1.07
50 INT306735 Positive_regulation of Positive_regulation of IL23A 4 0.26 3.25 1.04
51 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01
52 INT231560 Negative_regulation of Gene_expression of IL23A 3 0.11 2.41 0.99
53 INT233349 Regulation of Il12b 5 0.05 3.71 0.98
54 INT133173 Regulation of Negative_regulation of Il12b 2 0.04 0.52 0.97
55 INT258782 Regulation of Regulation of Il23a 1 0.13 0.77 0.92
56 INT181351 Transcription of Ccl5 5 0.64 2.19 0.9
57 INT140904 Negative_regulation of Gene_expression of Il23a 3 0.06 2.69 0.86
58 INT92649 Negative_regulation of Gene_expression of IL12B 3 0.03 2.23 0.86
59 INT181390 Negative_regulation of Positive_regulation of Ccl5 2 0.31 2.31 0.77
60 INT186283 Negative_regulation of Gene_expression of Il12b 2 0.13 7.92 0.74
61 INT262726 Localization of PML 6 0.57 7.13 0.72
62 INT158303 Transcription of IL23A 2 0.52 0.81 0.72
63 INT346122 Positive_regulation of Gene_expression of Il23r 1 0.14 1.03 0.7
64 INT306740 Localization of IL23A 3 0.58 2.66 0.69
65 INT116007 Negative_regulation of Mavs 1 0.03 0.08 0.69
66 INT48970 Positive_regulation of LILRB1 7 0.67 11.38 0.67
67 INT74155 Transcription of Il12b 3 0.60 1.45 0.66
68 INT156544 Regulation of Il12b 2 0.44 1.29 0.66
69 INT181394 Gene_expression of Il12rb1 2 0.25 2.01 0.64
70 INT181349 Positive_regulation of Localization of Ccl5 2 0.37 0.89 0.62
71 INT204767 Negative_regulation of Transcription of Il23a 2 0.19 2.24 0.62
72 INT162383 Positive_regulation of Il23r 1 0.69 0.41 0.59
73 INT150817 Protein_catabolism of Il23r 1 0.69 1.7 0.58
74 INT150818 Localization of Il23r 1 0.58 1.68 0.57
75 INT186277 Binding of Il12b 4 0.20 2.15 0.55
76 INT194225 Positive_regulation of Positive_regulation of Ccl5 1 0.07 1.13 0.55
77 INT134418 Regulation of LILRB1 3 0.44 2.7 0.5
78 INT84573 Regulation of Mavs 1 0.01 1.37 0.49
79 INT330393 Positive_regulation of Gene_expression of Il12b 2 0.49 1.24 0.48
80 INT8706 Positive_regulation of Localization of LILRB1 1 0.00 0.69 0.47
81 INT166728 Regulation of MAVS 1 0.32 0.15 0.44
82 INT233355 Positive_regulation of Localization of Il12b 2 0.11 0.99 0.43
83 INT185318 Negative_regulation of Transcription of Il12b 2 0.06 1.03 0.43
84 INT346479 Positive_regulation of DDX58 1 0.06 5.3 0.42
85 INT204768 Regulation of Gene_expression of Il23a 3 0.11 1.25 0.41
86 INT133569 Regulation of IL23A 2 0.12 0.86 0.41
87 INT268760 Positive_regulation of Binding of Ccl5 1 0.13 0.91 0.39
88 INT233356 Negative_regulation of Positive_regulation of Il12b 3 0.13 0.85 0.38
89 INT233350 Regulation of Gene_expression of Il12b 1 0.06 3.03 0.37
90 INT250885 Regulation of Gene_expression of IL23A 1 0.12 0.87 0.37
91 INT92652 Negative_regulation of Positive_regulation of IL12B 1 0.03 0.99 0.36
92 INT348180 Localization of IL23R 1 0.34 0.91 0.36
93 INT348181 Phosphorylation of IL23R 1 0.27 0.91 0.36
94 INT246029 Regulation of IL23R 1 0.21 2.83 0.35
95 INT240529 Regulation of Gene_expression of Il12rb1 1 0.11 0.22 0.33
96 INT348183 Binding of IL12B 1 0.46 0.97 0.33
97 INT346492 Protein_catabolism of MAVS 1 0.06 1.74 0.31
98 INT181343 Negative_regulation of Gene_expression of Il12rb1 1 0.05 1.8 0.31
99 INT230527 Regulation of Gene_expression of LILRB1 1 0.44 1.73 0.3
100 INT204786 Positive_regulation of Transcription of Il23a 1 0.17 1.08 0.29
101 INT167594 Regulation of Gene_expression of Il23r 1 0.25 0.88 0.29
102 INT336951 Positive_regulation of Binding of PML 1 0.09 2.02 0.28
103 INT216976 Positive_regulation of Positive_regulation of Il23a 3 0.08 0.16 0.27
104 INT329823 Negative_regulation of Il12b 1 0.42 0.57 0.27
105 INT289317 Positive_regulation of Localization of PML 1 0.23 1.09 0.26
106 INT278513 Regulation of Localization of PML 1 0.34 1.73 0.24
107 INT306742 Negative_regulation of Positive_regulation of IL23A 1 0.22 0.52 0.24
108 INT355279 Positive_regulation of Il12rb1 1 0.01 1.75 0.21
109 INT294675 Localization of Il12b 2 0.78 1.15 0.19
110 INT149051 Regulation of Il23r 1 0.26 0.37 0.17
111 INT119167 Positive_regulation of Transcription of Il12b 1 0.09 0.77 0.17
112 INT204974 Positive_regulation of Mavs 1 0.02 3.77 0.16
113 INT204989 Gene_expression of Mavs 3 0.02 0.86 0.15
114 INT230524 Binding of LILRB1 2 0.35 2.14 0.15
115 INT230522 Regulation of Regulation of LILRB1 1 0.44 0.87 0.15
116 INT233838 Regulation of Binding of Ccl5 1 0.21 1 0.15
117 INT346493 Binding of MAVS 1 0.03 0.54 0.15
118 INT274485 Gene_expression of IL12RB1 1 0.02 0.39 0.14
119 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12
120 INT237761 Phosphorylation of Il12b 1 0.09 0.49 0.11
121 INT349072 Positive_regulation of Gene_expression of PML 1 0.13 1.49 0.1
122 INT306733 Negative_regulation of Transcription of IL23A 1 0.22 0.31 0.1
123 INT282824 Regulation of PML 3 0.44 2.66 0.09
124 INT246434 Negative_regulation of Negative_regulation of Ccl5 1 0.40 1.72 0.09
125 INT217383 Regulation of Regulation of Mavs 1 0.01 0.79 0.08
126 INT316525 Regulation of Negative_regulation of Il23a 1 0.20 0.98 0.08
127 INT233354 Positive_regulation of Positive_regulation of Il12b 1 0.06 2.91 0.07
128 INT296069 Negative_regulation of Gene_expression of IL23R 1 0.07 0 0.07
129 INT186310 Positive_regulation of Binding of Il12b 1 0.15 1.07 0.07
130 INT97135 Positive_regulation of Localization of IL12B 2 0.49 0.92 0.05
131 INT298569 Negative_regulation of LILRB1 2 0.05 1.97 0.05
132 INT316528 Protein_catabolism of Il23a 1 0.39 0.69 0.05
133 INT290325 Binding of DDX58 1 0.04 0.52 0.05
134 INT217374 Positive_regulation of Regulation of Mavs 1 0.01 0.37 0.05
135 INT356186 Positive_regulation of Regulation of PML 1 0.49 1.14 0.04
136 INT230526 Positive_regulation of Positive_regulation of LILRB1 1 0.49 0.67 0.04
137 INT204980 Regulation of Gene_expression of Mavs 1 0.01 0.3 0.03
138 INT305355 Transcription of IL12B 1 0.52 0.46 0.03
139 INT346490 Phosphorylation of DDX58 1 0.07 1.03 0.03
140 INT164375 Negative_regulation of Il23r 1 0.30 0.08 0
141 INT330665 Negative_regulation of PML 1 0.13 1.15 0
142 INT273927 Transcription of Mavs 1 0.00 0 0
143 INT163943 Positive_regulation of Gene_expression of Il23r 1 0.39 0.09 0
144 INT189478 Regulation of Transcription of Ccl5 1 0.38 0.63 0
145 INT97143 Regulation of Localization of IL12B 1 0.08 0 0
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